JP2002529520A - プロピレングリコールおよびアルカン酸イソプロピルエステルを含む抗ウイルス製剤 - Google Patents
プロピレングリコールおよびアルカン酸イソプロピルエステルを含む抗ウイルス製剤Info
- Publication number
- JP2002529520A JP2002529520A JP2000582073A JP2000582073A JP2002529520A JP 2002529520 A JP2002529520 A JP 2002529520A JP 2000582073 A JP2000582073 A JP 2000582073A JP 2000582073 A JP2000582073 A JP 2000582073A JP 2002529520 A JP2002529520 A JP 2002529520A
- Authority
- JP
- Japan
- Prior art keywords
- weight
- composition
- composition according
- glucocorticoid
- hydrocortisone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- 230000008033 biological extinction Effects 0.000 description 1
- CJZGTCYPCWQAJB-UHFFFAOYSA-L calcium stearate Chemical compound [Ca+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O CJZGTCYPCWQAJB-UHFFFAOYSA-L 0.000 description 1
- 239000008116 calcium stearate Substances 0.000 description 1
- 235000013539 calcium stearate Nutrition 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 125000002091 cationic group Chemical group 0.000 description 1
- 229950009789 cetomacrogol 1000 Drugs 0.000 description 1
- 238000004040 coloring Methods 0.000 description 1
- 239000013066 combination product Substances 0.000 description 1
- 229940127555 combination product Drugs 0.000 description 1
- 238000002648 combination therapy Methods 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 125000002704 decyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])* 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 229940075882 denavir Drugs 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- UGMCXQCYOVCMTB-UHFFFAOYSA-K dihydroxy(stearato)aluminium Chemical compound CCCCCCCCCCCCCCCCCC(=O)O[Al](O)O UGMCXQCYOVCMTB-UHFFFAOYSA-K 0.000 description 1
- UYAAVKFHBMJOJZ-UHFFFAOYSA-N diimidazo[1,3-b:1',3'-e]pyrazine-5,10-dione Chemical compound O=C1C2=CN=CN2C(=O)C2=CN=CN12 UYAAVKFHBMJOJZ-UHFFFAOYSA-N 0.000 description 1
- 229940031578 diisopropyl adipate Drugs 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 230000006806 disease prevention Effects 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
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- 239000003974 emollient agent Substances 0.000 description 1
- 230000002996 emotional effect Effects 0.000 description 1
- UTBDYLQPXTWUDG-UHFFFAOYSA-N ethene;octadecanoic acid Chemical compound C=C.CCCCCCCCCCCCCCCCCC(O)=O UTBDYLQPXTWUDG-UHFFFAOYSA-N 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- MVPICKVDHDWCJQ-UHFFFAOYSA-N ethyl 3-pyrrolidin-1-ylpropanoate Chemical compound CCOC(=O)CCN1CCCC1 MVPICKVDHDWCJQ-UHFFFAOYSA-N 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 150000002191 fatty alcohols Chemical class 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000013355 food flavoring agent Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 230000004927 fusion Effects 0.000 description 1
- 239000003193 general anesthetic agent Substances 0.000 description 1
- 201000004946 genital herpes Diseases 0.000 description 1
- 125000005908 glyceryl ester group Chemical group 0.000 description 1
- 150000002334 glycols Chemical class 0.000 description 1
- 208000024963 hair loss Diseases 0.000 description 1
- 230000003676 hair loss Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
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- 229940078545 isocetyl stearate Drugs 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 229960003511 macrogol Drugs 0.000 description 1
- 235000019359 magnesium stearate Nutrition 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 239000004005 microsphere Substances 0.000 description 1
- 239000002480 mineral oil Substances 0.000 description 1
- 210000004877 mucosa Anatomy 0.000 description 1
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 description 1
- 230000001537 neural effect Effects 0.000 description 1
- 239000002736 nonionic surfactant Substances 0.000 description 1
- 229920000847 nonoxynol Polymers 0.000 description 1
- 125000003835 nucleoside group Chemical group 0.000 description 1
- 229920002113 octoxynol Polymers 0.000 description 1
- 229940066429 octoxynol Drugs 0.000 description 1
- 235000021313 oleic acid Nutrition 0.000 description 1
- 208000035824 paresthesia Diseases 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000037368 penetrate the skin Effects 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 229920001983 poloxamer Polymers 0.000 description 1
- 229920001992 poloxamer 407 Polymers 0.000 description 1
- 229940044476 poloxamer 407 Drugs 0.000 description 1
- 229920000136 polysorbate Polymers 0.000 description 1
- 229950008882 polysorbate Drugs 0.000 description 1
- 229920002451 polyvinyl alcohol Polymers 0.000 description 1
- 229940068984 polyvinyl alcohol Drugs 0.000 description 1
- 239000003755 preservative agent Substances 0.000 description 1
- 230000000069 prophylactic effect Effects 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 229940116423 propylene glycol diacetate Drugs 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- 238000005057 refrigeration Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- RYYKJJJTJZKILX-UHFFFAOYSA-M sodium octadecanoate Chemical compound [Na+].CCCCCCCCCCCCCCCCCC([O-])=O RYYKJJJTJZKILX-UHFFFAOYSA-M 0.000 description 1
- 229940080350 sodium stearate Drugs 0.000 description 1
- 229940045902 sodium stearyl fumarate Drugs 0.000 description 1
- 229960000776 sodium tetradecyl sulfate Drugs 0.000 description 1
- UPUIQOIQVMNQAP-UHFFFAOYSA-M sodium;tetradecyl sulfate Chemical compound [Na+].CCCCCCCCCCCCCCOS([O-])(=O)=O UPUIQOIQVMNQAP-UHFFFAOYSA-M 0.000 description 1
- 229940100515 sorbitan Drugs 0.000 description 1
- 229940114926 stearate Drugs 0.000 description 1
- 230000000475 sunscreen effect Effects 0.000 description 1
- 239000000516 sunscreening agent Substances 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
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- 239000007762 w/o emulsion Substances 0.000 description 1
- XOOUIPVCVHRTMJ-UHFFFAOYSA-L zinc stearate Chemical compound [Zn+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O XOOUIPVCVHRTMJ-UHFFFAOYSA-L 0.000 description 1
- 229940057977 zinc stearate Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Oncology (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9803929-0 | 1998-11-18 | ||
| SE9803929A SE9803929D0 (sv) | 1998-11-18 | 1998-11-18 | Antiviral formulation |
| PCT/SE1999/002043 WO2000029027A1 (en) | 1998-11-18 | 1999-11-12 | Antiviral formulations comprising propylene glycol and an isopropyl alkanoic acid ester |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011087438A Division JP5420583B2 (ja) | 1998-11-18 | 2011-04-11 | プロピレングリコールおよびアルカン酸イソプロピルエステルを含む抗ウイルス製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002529520A true JP2002529520A (ja) | 2002-09-10 |
| JP2002529520A5 JP2002529520A5 (enExample) | 2006-11-30 |
Family
ID=20413320
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000582073A Pending JP2002529520A (ja) | 1998-11-18 | 1999-11-12 | プロピレングリコールおよびアルカン酸イソプロピルエステルを含む抗ウイルス製剤 |
| JP2011087438A Expired - Lifetime JP5420583B2 (ja) | 1998-11-18 | 2011-04-11 | プロピレングリコールおよびアルカン酸イソプロピルエステルを含む抗ウイルス製剤 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011087438A Expired - Lifetime JP5420583B2 (ja) | 1998-11-18 | 2011-04-11 | プロピレングリコールおよびアルカン酸イソプロピルエステルを含む抗ウイルス製剤 |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP1131104B1 (enExample) |
| JP (2) | JP2002529520A (enExample) |
| KR (1) | KR100608963B1 (enExample) |
| CN (1) | CN1160128C (enExample) |
| AR (1) | AR023705A1 (enExample) |
| AT (1) | ATE288283T1 (enExample) |
| AU (1) | AU772435B2 (enExample) |
| CA (1) | CA2351463C (enExample) |
| DE (1) | DE69923584T2 (enExample) |
| DK (1) | DK1131104T3 (enExample) |
| EG (1) | EG23853A (enExample) |
| ES (1) | ES2233104T3 (enExample) |
| HK (1) | HK1042440B (enExample) |
| IL (2) | IL142702A0 (enExample) |
| MY (1) | MY122397A (enExample) |
| NZ (1) | NZ511832A (enExample) |
| PT (1) | PT1131104E (enExample) |
| SE (1) | SE9803929D0 (enExample) |
| TW (1) | TW589191B (enExample) |
| WO (1) | WO2000029027A1 (enExample) |
| ZA (1) | ZA200103335B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009221186A (ja) * | 2008-03-17 | 2009-10-01 | Medivir Ab | 抗ウイルス製剤 |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100956369B1 (ko) * | 2001-11-19 | 2010-05-10 | 메디진 아게 | 바이러스성 피부 질환 및 종양 질환 치료용 약제 |
| ZA200602544B (en) | 2003-10-09 | 2007-06-27 | Medigene Ag | The use of a polyphenol for the treatment of a cancerous or pre-cancerous lesion of the skin |
| ES2955089T3 (es) * | 2018-08-17 | 2023-11-28 | Ilko Ilac Sanayi Ve Ticaret Anonim Sirketi | Composición tópica estable en fase que comprende aciclovir e hidrocortisona |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996024355A1 (en) * | 1995-02-06 | 1996-08-15 | Astra Aktiebolag | Novel pharmaceutical combination |
| WO1998017316A1 (en) * | 1996-10-18 | 1998-04-30 | Cellegy Pharmaceuticals Inc. | Potent transdermal penetration enhancers |
-
1998
- 1998-11-18 SE SE9803929A patent/SE9803929D0/xx unknown
-
1999
- 1999-11-12 AU AU14364/00A patent/AU772435B2/en not_active Expired
- 1999-11-12 NZ NZ511832A patent/NZ511832A/en not_active IP Right Cessation
- 1999-11-12 EP EP99972109A patent/EP1131104B1/en not_active Expired - Lifetime
- 1999-11-12 DE DE69923584T patent/DE69923584T2/de not_active Expired - Lifetime
- 1999-11-12 HK HK02104279.2A patent/HK1042440B/zh not_active IP Right Cessation
- 1999-11-12 PT PT99972109T patent/PT1131104E/pt unknown
- 1999-11-12 CN CNB998133825A patent/CN1160128C/zh not_active Expired - Lifetime
- 1999-11-12 CA CA002351463A patent/CA2351463C/en not_active Expired - Lifetime
- 1999-11-12 ES ES99972109T patent/ES2233104T3/es not_active Expired - Lifetime
- 1999-11-12 JP JP2000582073A patent/JP2002529520A/ja active Pending
- 1999-11-12 IL IL14270299A patent/IL142702A0/xx active IP Right Grant
- 1999-11-12 KR KR1020017006232A patent/KR100608963B1/ko not_active Expired - Fee Related
- 1999-11-12 DK DK99972109T patent/DK1131104T3/da active
- 1999-11-12 AT AT99972109T patent/ATE288283T1/de active
- 1999-11-12 WO PCT/SE1999/002043 patent/WO2000029027A1/en not_active Ceased
- 1999-11-15 TW TW088119865A patent/TW589191B/zh not_active IP Right Cessation
- 1999-11-16 MY MYPI99004979A patent/MY122397A/en unknown
- 1999-11-16 EG EG146899A patent/EG23853A/xx active
- 1999-11-17 AR ARP990105846A patent/AR023705A1/es active IP Right Grant
-
2001
- 2001-04-19 IL IL142702A patent/IL142702A/en not_active IP Right Cessation
- 2001-04-24 ZA ZA200103335A patent/ZA200103335B/en unknown
-
2011
- 2011-04-11 JP JP2011087438A patent/JP5420583B2/ja not_active Expired - Lifetime
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1996024355A1 (en) * | 1995-02-06 | 1996-08-15 | Astra Aktiebolag | Novel pharmaceutical combination |
| WO1998017316A1 (en) * | 1996-10-18 | 1998-04-30 | Cellegy Pharmaceuticals Inc. | Potent transdermal penetration enhancers |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009221186A (ja) * | 2008-03-17 | 2009-10-01 | Medivir Ab | 抗ウイルス製剤 |
Also Published As
| Publication number | Publication date |
|---|---|
| HK1042440A1 (en) | 2002-08-16 |
| EG23853A (en) | 2007-11-06 |
| AU1436400A (en) | 2000-06-05 |
| AU772435B2 (en) | 2004-04-29 |
| TW589191B (en) | 2004-06-01 |
| CN1326364A (zh) | 2001-12-12 |
| DK1131104T3 (da) | 2005-03-14 |
| ES2233104T3 (es) | 2005-06-01 |
| IL142702A (en) | 2006-07-05 |
| HK1042440B (zh) | 2005-04-29 |
| EP1131104B1 (en) | 2005-02-02 |
| ZA200103335B (en) | 2002-07-24 |
| MY122397A (en) | 2006-04-29 |
| NZ511832A (en) | 2003-09-26 |
| ATE288283T1 (de) | 2005-02-15 |
| CN1160128C (zh) | 2004-08-04 |
| CA2351463C (en) | 2009-10-13 |
| DE69923584T2 (de) | 2006-03-23 |
| IL142702A0 (en) | 2002-03-10 |
| KR20010075720A (ko) | 2001-08-09 |
| PT1131104E (pt) | 2005-03-31 |
| EP1131104A1 (en) | 2001-09-12 |
| WO2000029027A1 (en) | 2000-05-25 |
| JP5420583B2 (ja) | 2014-02-19 |
| SE9803929D0 (sv) | 1998-11-18 |
| CA2351463A1 (en) | 2000-05-25 |
| AR023705A1 (es) | 2002-09-04 |
| JP2011157392A (ja) | 2011-08-18 |
| KR100608963B1 (ko) | 2006-08-09 |
| DE69923584D1 (de) | 2005-03-10 |
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