JP2002524457A - 抗不整脈薬として有用な置換ジヒドロベンゾピラン - Google Patents

抗不整脈薬として有用な置換ジヒドロベンゾピラン

Info

Publication number
JP2002524457A
JP2002524457A JP2000568842A JP2000568842A JP2002524457A JP 2002524457 A JP2002524457 A JP 2002524457A JP 2000568842 A JP2000568842 A JP 2000568842A JP 2000568842 A JP2000568842 A JP 2000568842A JP 2002524457 A JP2002524457 A JP 2002524457A
Authority
JP
Japan
Prior art keywords
alkyl
methyl
compound
trifluoromethyl
fluoroalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000568842A
Other languages
English (en)
Japanese (ja)
Inventor
ウィアード シュルツ マイケル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Publication of JP2002524457A publication Critical patent/JP2002524457A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000568842A 1998-09-04 1999-09-03 抗不整脈薬として有用な置換ジヒドロベンゾピラン Withdrawn JP2002524457A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9921898P 1998-09-04 1998-09-04
US60/099,218 1998-09-04
PCT/US1999/020306 WO2000014084A1 (en) 1998-09-04 1999-09-03 Substituted dihydrobenzopyrans useful as antiarrhythmic agents

Publications (1)

Publication Number Publication Date
JP2002524457A true JP2002524457A (ja) 2002-08-06

Family

ID=22273663

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000568842A Withdrawn JP2002524457A (ja) 1998-09-04 1999-09-03 抗不整脈薬として有用な置換ジヒドロベンゾピラン

Country Status (7)

Country Link
EP (1) EP1109801A1 (no)
JP (1) JP2002524457A (no)
AU (1) AU748612B2 (no)
CA (1) CA2341353A1 (no)
IL (1) IL141341A0 (no)
NO (1) NO20011038L (no)
WO (1) WO2000014084A1 (no)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536842A (ja) * 2005-04-12 2008-09-11 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング アミノアルキル−アミドメチル置換２−スルホニルアミノ）−３−ヒドロキシ−３，４−ジヒドロ−２ｈ−クロメン−６−イル誘導体およびそのカリウムチャンネル遮断薬としての使用
JP2009511551A (ja) * 2005-10-14 2009-03-19 プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ 心房細動の治療のための化合物
WO2010018867A1 (ja) * 2008-08-14 2010-02-18 日産化学工業株式会社 ジ置換ベンゾピラン化合物

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008536842A (ja) * 2005-04-12 2008-09-11 ゾルファイ ファーマスーティカルズ ゲゼルシャフト ミット ベシュレンクテル ハフツング アミノアルキル−アミドメチル置換２−スルホニルアミノ）−３−ヒドロキシ−３，４−ジヒドロ−２ｈ−クロメン−６−イル誘導体およびそのカリウムチャンネル遮断薬としての使用
JP2009511551A (ja) * 2005-10-14 2009-03-19 プロイェクト、デ、ビオメディシナ、シーマ、ソシエダッド、リミターダ 心房細動の治療のための化合物
WO2010018867A1 (ja) * 2008-08-14 2010-02-18 日産化学工業株式会社 ジ置換ベンゾピラン化合物
JPWO2010018867A1 (ja) * 2008-08-14 2012-01-26 日産化学工業株式会社 ジ置換ベンゾピラン化合物

Also Published As

Publication number Publication date
WO2000014084A1 (en) 2000-03-16
NO20011038L (no) 2001-05-04
AU748612B2 (en) 2002-06-06
AU5908599A (en) 2000-03-27
CA2341353A1 (en) 2000-03-16
IL141341A0 (en) 2002-03-10
NO20011038D0 (no) 2001-02-28
EP1109801A1 (en) 2001-06-27

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Legal Events

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A300 Application deemed to be withdrawn because no request for examination was validly filed

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Effective date: 20061107