NO20011038L - Substituerte dihydrobenzopyraner nyttige som antiarytmiske midler - Google Patents

Substituerte dihydrobenzopyraner nyttige som antiarytmiske midler

Info

Publication number
NO20011038L
NO20011038L NO20011038A NO20011038A NO20011038L NO 20011038 L NO20011038 L NO 20011038L NO 20011038 A NO20011038 A NO 20011038A NO 20011038 A NO20011038 A NO 20011038A NO 20011038 L NO20011038 L NO 20011038L
Authority
NO
Norway
Prior art keywords
useful
compounds
antiarrhythmic agents
formula
pharmaceutical compositions
Prior art date
Application number
NO20011038A
Other languages
English (en)
Other versions
NO20011038D0 (no
Inventor
Michael Wiard Scherz
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of NO20011038D0 publication Critical patent/NO20011038D0/no
Publication of NO20011038L publication Critical patent/NO20011038L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/70Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with two hydrocarbon radicals attached in position 2 and elements other than carbon and hydrogen in position 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)

Abstract

Beskrevet er nye dihydrobenzopyranforbindelser anvendbare som antiarytmi og mikrofibrillerende midler. Forbindelsene har en struktur i henhold til formel (A), eller et farma- søytisk akseptabelt salt, eller biohydrolyserbart amid, es- ter, eller imid derav, hvori Rl( Rj, R3, R,, R5, °9 R« er de- finert i spesifikasjonen. Formel (A) inkluderer også op- tiske isomerer, diastereomerer eller enantiomerer. Også be- skrevet er farmasøytiske sammensetninger og fremgangsmåter for å behandle forstyrrelser og tilstander karakterisert ved antiarytmi-aktivitet anvendende disse forbindelser el- ler de farmasøytiske sammensetninger inneholdende dem.
NO20011038A 1998-09-04 2001-02-28 Substituerte dihydrobenzopyraner nyttige som antiarytmiske midler NO20011038L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9921898P 1998-09-04 1998-09-04
PCT/US1999/020306 WO2000014084A1 (en) 1998-09-04 1999-09-03 Substituted dihydrobenzopyrans useful as antiarrhythmic agents

Publications (2)

Publication Number Publication Date
NO20011038D0 NO20011038D0 (no) 2001-02-28
NO20011038L true NO20011038L (no) 2001-05-04

Family

ID=22273663

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20011038A NO20011038L (no) 1998-09-04 2001-02-28 Substituerte dihydrobenzopyraner nyttige som antiarytmiske midler

Country Status (7)

Country Link
EP (1) EP1109801A1 (no)
JP (1) JP2002524457A (no)
AU (1) AU748612B2 (no)
CA (1) CA2341353A1 (no)
IL (1) IL141341A0 (no)
NO (1) NO20011038L (no)
WO (1) WO2000014084A1 (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7368582B2 (en) 2003-10-17 2008-05-06 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 2-(4-sulfonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl compounds, a process and intermediates for their production, and pharmaceutical compositions containing them
AU2006234295B2 (en) * 2005-04-12 2011-10-13 Solvay Pharmaceuticals Gmbh Aminoalkyl-amidomethyl-substituted 2-(4-sulphonylamino)-3-hydroxy-3,4-dihydro-2H-chromen-6-yl derivatives and their use as potassium channel blockers
ES2273599B1 (es) * 2005-10-14 2008-06-01 Universidad De Barcelona Compuestos para el tratamiento de la fibrilacion auricular.
JPWO2010018867A1 (ja) * 2008-08-14 2012-01-26 日産化学工業株式会社 ジ置換ベンゾピラン化合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19706675A1 (de) * 1997-02-20 1998-08-27 Hoechst Ag Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19742509A1 (de) * 1997-09-26 1999-04-01 Hoechst Marion Roussel De Gmbh Sulfonamid-substituierte Chromane, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltende pharmazeutische Zubereitungen

Also Published As

Publication number Publication date
AU748612B2 (en) 2002-06-06
IL141341A0 (en) 2002-03-10
AU5908599A (en) 2000-03-27
JP2002524457A (ja) 2002-08-06
NO20011038D0 (no) 2001-02-28
EP1109801A1 (en) 2001-06-27
CA2341353A1 (en) 2000-03-16
WO2000014084A1 (en) 2000-03-16

Similar Documents

Publication Publication Date Title
NO20024521L (no) Heterocyklisk sidekjede-inneholdende metalloproteaseinhibitorer
NO20001141L (no) Aromatisk C16-C20-substituert tetrahydro-prostaglandiner anvendbare som FP-agonister
CA2303801A1 (en) Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
CA2335285A1 (en) Bicyclic piperidine and piperazine compounds having 5-ht6 receptor affinity
DK0719253T3 (da) 3-amino-5-carboxy-substituerede piperidiner og 3-amino-4-carboxy-substituerede pyrrolidiner som tachykininantagonister
NO981415D0 (no) Nye N-arylpiperidin-forbindelser, en fremgangsmåte ved fremstilling derav og farmasöytiske preparater inneholdende slike
TR200000670T2 (tr) FP agonistleri olarak yararlı aromatik C16-C20- ikameli tetrahidro prostaglandinler.
NO963370L (no) Nye mercaptoacetylamido-1,3,4,5-tetrahydrobenzo[cÅazepin-3-on-disulfidderivater som er anvendbare som inhibitorer av enkefalinase og ACE
BR9909620A (pt) Inibidores de metaloproteases de hidroxamato de pirrolidina substituìdo
NO990896L (no) Bidentate metalloproteaseinhibitorer
NO984740L (no) Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler
NO20050612L (no) Pyrrolidinderivater som oksytocinantagonister
WO2000051993A3 (en) Dihetero-substituted metalloprotease inhibitors
NO20014241L (no) C16-umettede FP-selektive prostaglandinanaloger
DK1274685T3 (da) Et pyridin-N-oxid-derivat og fremgangsmåde til omdannelse deraf til farmaceutisk effektive forbindelser
DK0835868T3 (da) 2-aryl-3-aminoaryloxynaphthylforbindelser, mellemprodukter, sammensætninger og fremgangsmåder
PT1216245E (pt) Derivados sulfonil-hidrazida farmaceuticamente activos
CA2380326A1 (en) Novel 2-decarboxy-2-phosphinico prostaglandin f analogs
NO20011038L (no) Substituerte dihydrobenzopyraner nyttige som antiarytmiske midler
WO2001070720A3 (en) Carbocyclic side chain containing, n-substituted metalloprotease inhibitors
NO962360D0 (no) Nye indol, indazol-og benzisoksazolforbindelser, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem
HU9503775D0 (en) Benzene derivative useful for ischemic diseases
DK0421668T3 (da) 1,4-dihydro-4-oxo-3-quinolinderivater som selektivt toksiske, antibakterielle midler til pattedyr
NO970676D0 (no) Nye pseudopeptider avledet fra neurokininer, fremgangsmåte ved deres fremstilling og farmasöytiske sammensetninger inneholdende dem
DK0697404T3 (da) Nye, enantiomerrene pyridylcycloalkylethylaminer og deres salte, såvel som fremgangsmåder til deres fremstilling