JP2002521318A5 - - Google Patents

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Publication number
JP2002521318A5
JP2002521318A5 JP2000560859A JP2000560859A JP2002521318A5 JP 2002521318 A5 JP2002521318 A5 JP 2002521318A5 JP 2000560859 A JP2000560859 A JP 2000560859A JP 2000560859 A JP2000560859 A JP 2000560859A JP 2002521318 A5 JP2002521318 A5 JP 2002521318A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000560859A
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English (en)
Japanese (ja)
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JP2002521318A (ja
JP4719356B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US1999/016630 external-priority patent/WO2000004866A2/en
Publication of JP2002521318A publication Critical patent/JP2002521318A/ja
Publication of JP2002521318A5 publication Critical patent/JP2002521318A5/ja
Application granted granted Critical
Publication of JP4719356B2 publication Critical patent/JP4719356B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2000560859A 1998-07-23 1999-07-23 抗ガン剤及びdna複製阻害剤 Expired - Fee Related JP4719356B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9386998P 1998-07-23 1998-07-23
US60/093,869 1998-07-23
PCT/US1999/016630 WO2000004866A2 (en) 1998-07-23 1999-07-23 Preparation of thioarabinofuranosyl compounds and use thereof

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2010102499A Division JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Division JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びdna複製阻害剤

Publications (3)

Publication Number Publication Date
JP2002521318A JP2002521318A (ja) 2002-07-16
JP2002521318A5 true JP2002521318A5 (cg-RX-API-DMAC10.html) 2011-01-20
JP4719356B2 JP4719356B2 (ja) 2011-07-06

Family

ID=22241386

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2000560859A Expired - Fee Related JP4719356B2 (ja) 1998-07-23 1999-07-23 抗ガン剤及びdna複製阻害剤
JP2010102499A Pending JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Expired - Lifetime JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びdna複製阻害剤

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2010102499A Pending JP2010202655A (ja) 1998-07-23 2010-04-27 チオアラビノフラノシル化合物の製造方法
JP2010243705A Expired - Lifetime JP5357857B2 (ja) 1998-07-23 2010-10-29 抗ガン剤及びdna複製阻害剤

Country Status (9)

Country Link
US (5) US6576621B1 (cg-RX-API-DMAC10.html)
EP (3) EP1100512B1 (cg-RX-API-DMAC10.html)
JP (3) JP4719356B2 (cg-RX-API-DMAC10.html)
AT (1) ATE531376T1 (cg-RX-API-DMAC10.html)
AU (1) AU747012B2 (cg-RX-API-DMAC10.html)
CA (1) CA2338415C (cg-RX-API-DMAC10.html)
ES (3) ES2402799T3 (cg-RX-API-DMAC10.html)
NZ (1) NZ509405A (cg-RX-API-DMAC10.html)
WO (1) WO2000004866A2 (cg-RX-API-DMAC10.html)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4719356B2 (ja) * 1998-07-23 2011-07-06 サザン・リサーチ・インスティテュート 抗ガン剤及びdna複製阻害剤
AU2003257651A1 (en) * 2002-08-22 2004-03-11 Geneticlab Co., Ltd. 4'-thionucleotide
US7524831B2 (en) * 2005-03-02 2009-04-28 Schering Corporation Treatments for Flaviviridae virus infection
JP5417184B2 (ja) * 2007-03-23 2014-02-12 サザン リサーチ インスティテュート 関節炎を治療及び予防する方法
AR064165A1 (es) 2007-12-06 2009-03-18 Richmond Sa Com Ind Y Financie Un procedimiento para la preparacion de capecitabina e intermediarios utilizables en dicho procedimiento
WO2009158412A2 (en) * 2008-06-25 2009-12-30 Endo Pharmaceuticals Solutions Inc. Sustained delivery of exenatide and other polypeptides
US20110218170A1 (en) * 2010-03-02 2011-09-08 Southern Research Institute Use of 2'-deoxy-4'-thiocytidine and its analogues as dna hypomethylating anticancer agents
NZ701245A (en) 2012-03-28 2015-12-24 Fujifilm Corp Salt of 1-(2-deoxy-2-fluoro-4-thio-β-d-arabinofuranosyl)cytosine
WO2015125781A1 (ja) 2014-02-18 2015-08-27 富士フイルム株式会社 チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物
JP6351107B2 (ja) * 2014-02-18 2018-07-04 富士フイルム株式会社 チオラン骨格型糖化合物の製造方法およびチオラン骨格型糖化合物
JP6245527B2 (ja) * 2014-03-24 2017-12-13 富士フイルム株式会社 チオラン環もしくはチアン環骨格を有する化合物の製造方法
TWI678373B (zh) 2014-10-31 2019-12-01 日商富士軟片股份有限公司 硫代核苷衍生物或其鹽及醫藥組合物
WO2016189055A1 (en) * 2015-05-27 2016-12-01 Idenix Pharmaceuticals Llc Nucleotides for the treatment of cancer
WO2017091836A1 (en) * 2015-11-25 2017-06-01 University Of South Carolina Enhancement of cytarabine activity by inhibiting cdk8/19
KR102198656B1 (ko) 2016-08-31 2021-01-05 후지필름 가부시키가이샤 항종양제, 항종양 효과 증강제 및 항종양용 키트
CA3089728C (en) 2018-01-29 2023-01-10 Fujifilm Corporation Antitumor agent for biliary tract cancer and method for treating biliary tract cancer
CA3097003A1 (en) * 2018-04-19 2019-10-24 Southern Research Institute 4'-thio-nucleotide and -nucleoside prodrugs for the treatment of cancer
AU2020287343A1 (en) * 2019-06-05 2021-12-09 Southern Research Institute Thiarabine- and thiarabine prodrug-based treatments
CN115768432A (zh) 2020-04-23 2023-03-07 南方研究院 使用4’-硫代-5-氮杂-2’-脱氧胞苷来治疗血癌的组合物及其用途

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3207852B2 (ja) * 1989-09-15 2001-09-10 サザン リサーチ インスティテュート 抗ウィルス剤及び抗癌剤としての2′―デオキシ―4′―チオリボヌクレオシド
IE74701B1 (en) * 1989-10-04 1997-07-30 Univ Birmingham Further antiviral pyrimidine nucleosides
EP0461225B1 (en) * 1989-12-08 1998-03-18 City Of Hope Circumvention of human tumor drug resistance
JPH09249690A (ja) 1995-07-14 1997-09-22 Yamasa Shoyu Co Ltd 4’−チオアラビノプリンヌクレオシド
JPH0925289A (ja) 1995-07-14 1997-01-28 Yamasa Shoyu Co Ltd 4’−チオアラビノピリミジンヌクレオシドの製造方法
JP2943690B2 (ja) 1996-04-17 1999-08-30 日本電気株式会社 セル衝突検出装置
JP2001525667A (ja) 1997-05-09 2001-12-11 リボザイム・ファーマシューティカルズ・インコーポレーテッド C−rafの発現レベルに関係した疾患または状態の酵素核酸処置
US6548657B1 (en) * 1997-06-09 2003-04-15 Ribozyme Pharmaceuticals, Inc. Method for screening nucleic acid catalysts
WO1999043690A1 (en) 1998-02-25 1999-09-02 Rational Drug Design Laboratories L-4'-arabinofuranonucleoside compound and medicine composition comprising the same
JP4719356B2 (ja) * 1998-07-23 2011-07-06 サザン・リサーチ・インスティテュート 抗ガン剤及びdna複製阻害剤

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