JP2002520280A - トコトリエノールを使用した骨疾患を処置および予防するための組成物および方法 - Google Patents
トコトリエノールを使用した骨疾患を処置および予防するための組成物および方法Info
- Publication number
- JP2002520280A JP2002520280A JP2000558813A JP2000558813A JP2002520280A JP 2002520280 A JP2002520280 A JP 2002520280A JP 2000558813 A JP2000558813 A JP 2000558813A JP 2000558813 A JP2000558813 A JP 2000558813A JP 2002520280 A JP2002520280 A JP 2002520280A
- Authority
- JP
- Japan
- Prior art keywords
- tocotrienol
- bone
- composition
- vitamin
- tocotrienols
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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- 229930003802 tocotrienol Natural products 0.000 title claims abstract description 83
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- 238000000034 method Methods 0.000 title claims abstract description 34
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- GJJVAFUKOBZPCB-ZGRPYONQSA-N (r)-3,4-dihydro-2-methyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2h-1-benzopyran-6-ol Chemical class OC1=CC=C2OC(CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)(C)CCC2=C1 GJJVAFUKOBZPCB-ZGRPYONQSA-N 0.000 claims abstract description 40
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- 239000003826 tablet Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229940036555 thyroid hormone Drugs 0.000 description 1
- 239000005495 thyroid hormone Substances 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 230000000699 topical effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 229940046728 tumor necrosis factor alpha inhibitor Drugs 0.000 description 1
- 239000002451 tumor necrosis factor inhibitor Substances 0.000 description 1
- 230000004584 weight gain Effects 0.000 description 1
- 235000019786 weight gain Nutrition 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 description 1
- 229910000368 zinc sulfate Inorganic materials 0.000 description 1
- 229960001763 zinc sulfate Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9210198P | 1998-07-08 | 1998-07-08 | |
| US60/092,101 | 1998-07-08 | ||
| PCT/US1999/015452 WO2000002553A1 (fr) | 1998-07-08 | 1999-07-08 | Utilisation de procedes et de compositions a base de tocotrienols pour traiter et prevenir les maladies osseuses |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JP2002520280A true JP2002520280A (ja) | 2002-07-09 |
Family
ID=22231570
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000558813A Withdrawn JP2002520280A (ja) | 1998-07-08 | 1999-07-08 | トコトリエノールを使用した骨疾患を処置および予防するための組成物および方法 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP1109548A4 (fr) |
| JP (1) | JP2002520280A (fr) |
| CN (1) | CN1316903A (fr) |
| AU (1) | AU4732499A (fr) |
| ID (1) | ID28460A (fr) |
| WO (1) | WO2000002553A1 (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007506751A (ja) * | 2003-09-24 | 2007-03-22 | グラクソ グループ リミテッド | カルシウム拮抗化合物 |
| JP5967936B2 (ja) * | 2009-03-13 | 2016-08-10 | 株式会社明治 | 骨折リスクの低減及び／又は骨折の予防のための組成物 |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8669282B2 (en) * | 2000-10-31 | 2014-03-11 | Hill's Pet Nutrition, Inc. | Companion animal compositions including lipoic acid and methods of use thereof |
| US20020076470A1 (en) | 2000-10-31 | 2002-06-20 | Colgate-Palmolive Company | Composition and method |
| WO2002055071A1 (fr) * | 2001-01-15 | 2002-07-18 | Kgk Synergize | Compositions et methodes de regulation du taux de lipoproteines et de l'hypercholesterolemie au moyen de limonoides, de flavonoides et de tocotrienols |
| IL161162A0 (en) * | 2001-10-10 | 2004-08-31 | Pharmacia Italia Spa | Methods for preventing and treating bone loss with steroid compounds |
| EP1514540B1 (fr) * | 2002-05-01 | 2014-08-27 | Hayashibara Co., Ltd. | Agents de renforcement de tissus contenant du calcium et utilisation correspondante |
| FR2841472B1 (fr) * | 2002-06-28 | 2006-02-24 | Agronomique Inst Nat Rech | Composition nutritionnelle ou therapeutique contenant le compose hesperidine ou l'un de ses derives |
| FR2899106B1 (fr) * | 2002-11-19 | 2015-04-24 | Engelhard Lyon | Utilisation d'une substance pour limiter et/ou prevenir la modification d'au moins un parametre biologique modifie au cours d'une irradiation |
| WO2006024096A1 (fr) * | 2004-08-31 | 2006-03-09 | Chemgenex Pharmaceuticals Limited | Procédé servant à moduler l'ostéoclastogénèse |
| MX2007003968A (es) * | 2004-10-01 | 2008-03-04 | Ramscor Inc | Composiciones de farmaco de liberacion sostenida convenientemente implantables. |
| US20080038316A1 (en) | 2004-10-01 | 2008-02-14 | Wong Vernon G | Conveniently implantable sustained release drug compositions |
| CN104304671A (zh) | 2004-12-29 | 2015-01-28 | 希尔氏宠物营养品公司 | 抑制动物学习和/或记忆减退的方法 |
| DK1906912T3 (da) | 2005-07-14 | 2012-12-03 | Hills Pet Nutrition Inc | Fremgangsmåde til forlængelse af et dyrs levetid |
| US8288369B2 (en) * | 2006-06-27 | 2012-10-16 | University Of South Florida | Delta-tocotrienol treatment and prevention of pancreatic cancer |
| JP5337405B2 (ja) * | 2007-09-17 | 2013-11-06 | ザ・ホスピタル・フォー・シック・チルドレン | ゴーシェ病の治療方法 |
| AU2016200420B2 (en) * | 2008-12-30 | 2017-03-02 | Hill's Pet Nutrition, Inc. | Companion animal compositions including lipoic acid and methods of use thereof |
| NL2008294C2 (en) * | 2011-05-20 | 2013-08-19 | Friesland Brands Bv | Food composition comprising vitamin k and saturated fat. |
| US9132117B2 (en) | 2013-06-17 | 2015-09-15 | Kgk Synergize, Inc | Compositions and methods for glycemic control of subjects with impaired fasting glucose |
| AU2014293314B2 (en) * | 2013-07-22 | 2018-07-12 | Ohio State Innovation Foundation | Methods for reducing the occurrence of hot flashes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0645533B2 (ja) * | 1985-02-09 | 1994-06-15 | ライオン株式会社 | 化粧料 |
| US5574063A (en) * | 1989-10-12 | 1996-11-12 | Perricone; Nicholas V. | Method and compositions for topical application of ascorbic acid fatty acid esters for treatment and/or prevention of skin damage |
-
1999
- 1999-07-06 ID IDW20010301A patent/ID28460A/id unknown
- 1999-07-08 EP EP99930883A patent/EP1109548A4/fr not_active Withdrawn
- 1999-07-08 WO PCT/US1999/015452 patent/WO2000002553A1/fr not_active Application Discontinuation
- 1999-07-08 JP JP2000558813A patent/JP2002520280A/ja not_active Withdrawn
- 1999-07-08 CN CN99810684A patent/CN1316903A/zh active Pending
- 1999-07-08 AU AU47324/99A patent/AU4732499A/en not_active Abandoned
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007506751A (ja) * | 2003-09-24 | 2007-03-22 | グラクソ グループ リミテッド | カルシウム拮抗化合物 |
| JP5967936B2 (ja) * | 2009-03-13 | 2016-08-10 | 株式会社明治 | 骨折リスクの低減及び／又は骨折の予防のための組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU4732499A (en) | 2000-02-01 |
| CN1316903A (zh) | 2001-10-10 |
| ID28460A (id) | 2001-05-24 |
| EP1109548A1 (fr) | 2001-06-27 |
| EP1109548A4 (fr) | 2001-12-12 |
| WO2000002553A1 (fr) | 2000-01-20 |
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| Date | Code | Title | Description |
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| A300 | Application deemed to be withdrawn because no request for examination was validly filed |
Free format text: JAPANESE INTERMEDIATE CODE: A300 Effective date: 20061003 |