JP2002520101A - 電気的に補助される化粧用薬剤の局部送達法および装置 - Google Patents

電気的に補助される化粧用薬剤の局部送達法および装置

Info

Publication number
JP2002520101A
JP2002520101A JP2000558877A JP2000558877A JP2002520101A JP 2002520101 A JP2002520101 A JP 2002520101A JP 2000558877 A JP2000558877 A JP 2000558877A JP 2000558877 A JP2000558877 A JP 2000558877A JP 2002520101 A JP2002520101 A JP 2002520101A
Authority
JP
Japan
Prior art keywords
skin
pulse generator
composition
hand
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000558877A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002520101A5 (cg-RX-API-DMAC7.html
Inventor
ザン,レイ
ホフマン,ガンター,エー.
Original Assignee
ジェネトロニクス、インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ジェネトロニクス、インコーポレーテッド filed Critical ジェネトロニクス、インコーポレーテッド
Publication of JP2002520101A publication Critical patent/JP2002520101A/ja
Publication of JP2002520101A5 publication Critical patent/JP2002520101A5/ja
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0412Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
    • A61N1/0416Anode and cathode
    • A61N1/0424Shape of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/325Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0432Anode and cathode
    • A61N1/0436Material of the electrode
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0428Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
    • A61N1/0448Drug reservoir
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/02Details
    • A61N1/04Electrodes
    • A61N1/0404Electrodes for external use
    • A61N1/0408Use-related aspects
    • A61N1/0468Specially adapted for promoting wound healing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Electrotherapy Devices (AREA)
JP2000558877A 1998-07-13 1999-07-13 電気的に補助される化粧用薬剤の局部送達法および装置 Pending JP2002520101A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9254198P 1998-07-13 1998-07-13
US60/092,541 1998-07-13
PCT/US1999/015754 WO2000002620A1 (en) 1998-07-13 1999-07-13 Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications

Publications (2)

Publication Number Publication Date
JP2002520101A true JP2002520101A (ja) 2002-07-09
JP2002520101A5 JP2002520101A5 (cg-RX-API-DMAC7.html) 2006-08-24

Family

ID=22233728

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000558877A Pending JP2002520101A (ja) 1998-07-13 1999-07-13 電気的に補助される化粧用薬剤の局部送達法および装置

Country Status (6)

Country Link
US (2) US6302874B1 (cg-RX-API-DMAC7.html)
EP (1) EP1102608A4 (cg-RX-API-DMAC7.html)
JP (1) JP2002520101A (cg-RX-API-DMAC7.html)
AU (1) AU761522B2 (cg-RX-API-DMAC7.html)
CA (1) CA2337129A1 (cg-RX-API-DMAC7.html)
WO (1) WO2000002620A1 (cg-RX-API-DMAC7.html)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007521258A (ja) * 2003-06-23 2007-08-02 トランスファーマ メディカル リミテッド 化粧剤用経皮送達システム
JP2011041705A (ja) * 2009-08-21 2011-03-03 Kyushu Hitachi Maxell Ltd 美容装置
JP2011519640A (ja) * 2008-05-09 2011-07-14 フェンジアン・リミテッド 患者の健康の回復に用いる複数の電子
JP2013158441A (ja) * 2012-02-03 2013-08-19 Hitachi Maxell Ltd 唇用美容器具、および唇の美容方法
JP2020137720A (ja) * 2019-02-27 2020-09-03 パナソニックIpマネジメント株式会社 美容装置およびその経路形成機構

Families Citing this family (152)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2428250A1 (en) * 1998-07-13 2012-03-14 Genetronics, Inc. Skin and muscle-targeted gene therapy by pulsed electrical field
US6678556B1 (en) * 1998-07-13 2004-01-13 Genetronics, Inc. Electrical field therapy with reduced histopathological change in muscle
AU761522B2 (en) * 1998-07-13 2003-06-05 Genetronics, Inc. Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications
US7922709B2 (en) 1998-07-13 2011-04-12 Genetronics, Inc. Enhanced delivery of naked DNA to skin by non-invasive in vivo electroporation
US6887260B1 (en) * 1998-11-30 2005-05-03 Light Bioscience, Llc Method and apparatus for acne treatment
US20060212025A1 (en) * 1998-11-30 2006-09-21 Light Bioscience, Llc Method and apparatus for acne treatment
US6283956B1 (en) 1998-11-30 2001-09-04 David H. McDaniels Reduction, elimination, or stimulation of hair growth
US9192780B2 (en) 1998-11-30 2015-11-24 L'oreal Low intensity light therapy for treatment of retinal, macular, and visual pathway disorders
US6936044B2 (en) * 1998-11-30 2005-08-30 Light Bioscience, Llc Method and apparatus for the stimulation of hair growth
WO2000047274A1 (en) * 1999-02-10 2000-08-17 Gmp Drug Delivery, Inc. Iontophoresis, electroporation and combination patches for local drug delivery
US7197359B1 (en) 1999-10-14 2007-03-27 Pola Chemical Industries Inc. Compositions for electroporation
US7110826B2 (en) * 2000-01-18 2006-09-19 Shingo Motoi Cosmetic use alternating current wave forms and cosmetic device
US20020040203A1 (en) * 2000-02-25 2002-04-04 Arindam Sen Method for transdermal or intradermal delivery of molecules
US6882884B1 (en) * 2000-10-13 2005-04-19 Soundskin, L.L.C. Process for the stimulation of production of extracellular dermal proteins in human tissue
US20050274322A1 (en) * 2001-02-26 2005-12-15 Lee Chung J Reactor for producing reactive intermediates for low dielectric constant polymer thin films
US20040255862A1 (en) * 2001-02-26 2004-12-23 Lee Chung J. Reactor for producing reactive intermediates for low dielectric constant polymer thin films
US6881447B2 (en) * 2002-04-04 2005-04-19 Dielectric Systems, Inc. Chemically and electrically stabilized polymer films
US6980854B2 (en) * 2001-04-06 2005-12-27 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery of lidocaine and/or other drugs
US6748266B2 (en) * 2001-04-06 2004-06-08 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US7010343B2 (en) 2001-04-06 2006-03-07 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
AU2001290175B2 (en) * 2001-04-06 2006-03-16 Mattioli Engineering Ltd. Apparatus for skin absorption enhancement
US7496401B2 (en) * 2001-04-06 2009-02-24 Mattioli Engineering Ltd Method and apparatus for skin absorption enhancement and transdermal drug delivery
US6687537B2 (en) * 2001-04-06 2004-02-03 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and cellulite reduction
US6743215B2 (en) 2001-04-06 2004-06-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and cellulite reduction
US7083580B2 (en) * 2001-04-06 2006-08-01 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US7520875B2 (en) 2001-04-06 2009-04-21 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
ITTO20010534A1 (it) * 2001-06-04 2002-12-04 Igea Srl Dispositivo e metodo per elettroporazione che riduce la contrazione muscolare e la sensazione di dolore.
US7245963B2 (en) * 2002-03-07 2007-07-17 Advisys, Inc. Electrode assembly for constant-current electroporation and use
US8209006B2 (en) * 2002-03-07 2012-06-26 Vgx Pharmaceuticals, Inc. Constant current electroporation device and methods of use
FR2840533B1 (fr) * 2002-06-11 2005-04-15 Guinot Dispositif d'ionophorese transcutanee utilisant un champ electrique de surface
GB2390022A (en) * 2002-06-27 2003-12-31 Kieron Loy Hand-held iontophoresis device for application to skin pre-treated with a medicament or cosmetic
US7785623B2 (en) * 2002-10-01 2010-08-31 Keller Brian C Compositions and methods useful for the reduction of fine lines and wrinkles
US20050058701A1 (en) * 2003-01-29 2005-03-17 Yossi Gross Active drug delivery in the gastrointestinal tract
WO2004066903A2 (en) * 2003-01-29 2004-08-12 E-Pill Pharma Ltd. Active drug delivery in the gastrointestinal tract
US20040267240A1 (en) * 2003-01-29 2004-12-30 Yossi Gross Active drug delivery in the gastrointestinal tract
KR20060041161A (ko) 2003-04-10 2006-05-11 라이트 바이오사이언스, 엘엘씨 세포 증식 및 유전자 발현의 조절을 위한 광조절 방법 및광조절 장치
US8734421B2 (en) 2003-06-30 2014-05-27 Johnson & Johnson Consumer Companies, Inc. Methods of treating pores on the skin with electricity
US7477940B2 (en) * 2003-06-30 2009-01-13 J&J Consumer Companies, Inc. Methods of administering an active agent to a human barrier membrane with galvanic generated electricity
US7480530B2 (en) * 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Device for treatment of barrier membranes
US7477939B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of treating a wound with galvanic generated electricity
US7479133B2 (en) * 2003-06-30 2009-01-20 Johnson & Johnson Consumer Companies, Inc. Methods of treating acne and rosacea with galvanic generated electricity
US7486989B2 (en) * 2003-06-30 2009-02-03 Johnson & Johnson Consumer Companies, Inc. Device for delivery of oxidizing agents to barrier membranes
US7476222B2 (en) 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of reducing the appearance of pigmentation with galvanic generated electricity
US7477938B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Cosumer Companies, Inc. Device for delivery of active agents to barrier membranes
US7507228B2 (en) * 2003-06-30 2009-03-24 Johnson & Johnson Consumer Companies, Inc. Device containing a light emitting diode for treatment of barrier membranes
US20040265395A1 (en) * 2003-06-30 2004-12-30 Ying Sun Device for delivery of reducing agents to barrier membranes
US7477941B2 (en) * 2003-06-30 2009-01-13 Johnson & Johnson Consumer Companies, Inc. Methods of exfoliating the skin with electricity
ES2572976T3 (es) 2003-07-31 2016-06-03 Gentlewaves Llc Sistema y método para el tratamiento fotodinámico de la piel
US6962871B2 (en) * 2004-03-31 2005-11-08 Dielectric Systems, Inc. Composite polymer dielectric film
US7094661B2 (en) * 2004-03-31 2006-08-22 Dielectric Systems, Inc. Single and dual damascene techniques utilizing composite polymer dielectric film
US7309395B2 (en) 2004-03-31 2007-12-18 Dielectric Systems, Inc. System for forming composite polymer dielectric film
EP1740268A2 (en) * 2004-04-23 2007-01-10 Standen Ltd. Treating a tumor or the like with electric fields at different frequencies
US20060201426A1 (en) * 2004-05-25 2006-09-14 Lee Chung J Reactor for Producing Reactive Intermediates for Transport Polymerization
US7315758B2 (en) * 2004-06-03 2008-01-01 Lynntech, Inc. Transdermal delivery of therapeutic agent
CA2572870A1 (en) * 2004-07-06 2006-01-12 Transpharma Medical Ltd. Delivery system for transdermal immunization
US20060046044A1 (en) * 2004-08-24 2006-03-02 Lee Chung J Porous composite polymer dielectric film
US20060264804A1 (en) * 2005-04-07 2006-11-23 Yoram Karmon Device and kit for delivery of encapsulated substances and methods of use thereof
EP1885437A2 (en) * 2005-05-19 2008-02-13 E-Pill Pharma Ltd. Ingestible device for nitric oxide production in tissue
US20060274474A1 (en) * 2005-06-01 2006-12-07 Lee Chung J Substrate Holder
US20060275547A1 (en) * 2005-06-01 2006-12-07 Lee Chung J Vapor Phase Deposition System and Method
US20070009542A1 (en) * 2005-07-05 2007-01-11 Galit Levin Method and device for transdermal immunization
US20070021803A1 (en) * 2005-07-22 2007-01-25 The Foundry Inc. Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction
US20070185431A1 (en) * 2006-02-03 2007-08-09 Kern Dale G Galvanic Current Skin Treatment
PT3524316T (pt) 2006-10-17 2024-11-29 Inovio Pharmaceuticals Inc Dispositivos de eletroporação para eletroporação de células em mamíferos
EP2101863A2 (en) * 2006-11-24 2009-09-23 Koninklijke Philips Electronics N.V. Iontophoretic device
US7930036B1 (en) 2007-02-23 2011-04-19 Pravin Joshi Tactile application of herboelectrical stimulation to augment mammary glands
JP2011504111A (ja) * 2007-05-21 2011-02-03 サイト パルス サイエンシズ、インコーポレイテッド ポリヌクレオチドワクチンを哺乳類の皮膚に送達するための方法及び装置
WO2008146224A2 (en) 2007-05-25 2008-12-04 Compex Medical S.A. Wound healing electrode set
US8197844B2 (en) 2007-06-08 2012-06-12 Activatek, Inc. Active electrode for transdermal medicament administration
US9037229B2 (en) * 2007-10-09 2015-05-19 Syneron Medical Ltd Magnetic patch coupling
JP2011505899A (ja) 2007-12-05 2011-03-03 シネロン メディカル リミテッド 使い捨て可能な電磁気エネルギーアプリケータ及びそれを使用する方法
MX2010007860A (es) 2008-01-17 2010-11-30 Syneron Medical Ltd Un aparato de eliminacion de vello para uso personal y metodo para usarlo.
US8862223B2 (en) 2008-01-18 2014-10-14 Activatek, Inc. Active transdermal medicament patch and circuit board for same
KR20100115748A (ko) 2008-01-24 2010-10-28 시네론 메디컬 리미티드 지방 조직 치료 장치, 기기, 및 방법
US20090299266A1 (en) * 2008-06-02 2009-12-03 Mattioli Engineering Ltd. Method and apparatus for skin absorption enhancement and transdermal drug delivery
US20100030058A1 (en) * 2008-07-31 2010-02-04 Thomas Mammone Methods of Treating Wrinkles, Developing Wrinkle Treatments And Evaluating Treatment Efficacy, Based On Newly Discovered Similarities Between Wrinkles And Skin Wounds
US8150525B2 (en) 2008-08-27 2012-04-03 Johnson & Johnson Consumer Companies, Inc. Treatment of hyperhydrosis
EP2591745B1 (en) 2008-09-21 2015-01-21 Syneron Medical Ltd. Apparatus for personal skin treatment
TWM352263U (en) * 2008-10-29 2009-03-11 Hong-Jiang Shao Micro-current massage bra pad
US8606366B2 (en) 2009-02-18 2013-12-10 Syneron Medical Ltd. Skin treatment apparatus for personal use and method for using same
US20120089232A1 (en) 2009-03-27 2012-04-12 Jennifer Hagyoung Kang Choi Medical devices with galvanic particulates
US20100286587A1 (en) * 2009-05-07 2010-11-11 Yossi Gross Sublingual electrical drug delivery
US8414559B2 (en) 2009-05-07 2013-04-09 Rainbow Medical Ltd. Gastroretentive duodenal pill
KR20120091335A (ko) 2009-11-13 2012-08-17 존슨 앤드 존슨 컨수머 캄파니즈, 인코포레이티드 갈바닉 피부 치료 장치
US9227021B2 (en) 2010-06-29 2016-01-05 Genesis Biosystems, Inc. Microneedle roller (MNR) infusion system
US11191953B2 (en) * 2010-08-19 2021-12-07 Electrocore, Inc. Systems and methods for vagal nerve stimulation
EP2611500A4 (en) * 2010-09-05 2014-03-12 Venus Concept Ltd SELF-OPERATED AESTHETIC DEVICE WITH ONE SUBSTRATE
US20120076808A1 (en) 2010-09-27 2012-03-29 China Agricultural University Combined antigen and dna vaccine for preventing and treating autoimmune diseases
WO2013043267A1 (en) 2011-09-22 2013-03-28 Djo, Llc Devices and system for treating pain with electrical stimulation
RU2014119857A (ru) * 2011-10-19 2015-11-27 Ньюро Рисорс Груп, Инк. Самонаправляющийся электрод для стимуляции
WO2013096520A1 (en) * 2011-12-19 2013-06-27 David Jonathan Fluid skin treatment device
CN103239734B (zh) 2012-02-10 2016-02-24 北京艾棣维欣生物技术有限公司 用于预防和/或治疗呼吸道合胞病毒感染的疫苗
CN104812401B (zh) 2012-12-13 2017-10-13 宾夕法尼亚大学理事会 Wt1疫苗
US10364451B2 (en) 2013-05-30 2019-07-30 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
WO2014194244A1 (en) 2013-05-30 2014-12-04 Duke University Enzyme-catalyzed synthesis of site-specific and stoichiometric biomolecule-polymer conjugates
US10392611B2 (en) 2013-05-30 2019-08-27 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US11013917B2 (en) * 2013-06-21 2021-05-25 Newsouth Innovations Pty Limited Method and apparatus for close-field electroporation
EP3054972B1 (en) 2013-10-07 2019-02-27 The Trustees Of The University Of Pennsylvania Vaccines with interleukin-33 as an adjuvant
US10370664B2 (en) 2013-11-07 2019-08-06 University Of Southern California Use of IKK epsilon inhibitors to activate NFAT and T cell response
EP3964231A1 (en) 2013-11-14 2022-03-09 Inovio Pharmaceuticals, Inc. Hiv-1 env dna vaccine plus protein boost
KR20230122181A (ko) 2013-11-29 2023-08-22 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 중동 호흡기 증후군 코로나바이러스(MERS-CoV) 백신
EP3092004A4 (en) 2014-01-06 2017-02-22 The Trustees Of The University Of Pennsylvania Pd1 and pdl1 antibodies and vaccine combinations and use of same for immunotherapy
EP3137160B1 (en) * 2014-05-02 2023-04-19 Koninklijke Philips N.V. A device for inactivating bacteria
KR102586707B1 (ko) 2014-10-01 2023-10-11 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 항원 및 어쥬번트로서 인터류킨-21을 갖는 백신
KR20240132103A (ko) 2015-01-29 2024-09-02 더 트러스티스 오브 더 유니버시티 오브 펜실바니아 관문 억제제 및 백신 조합 및 면역요법을 위한 이들의 사용
US10385115B2 (en) 2015-03-26 2019-08-20 Duke University Fibronectin type III domain-based fusion proteins
EP3331557B1 (en) 2015-08-04 2021-04-07 Duke University Genetically encoded intrinsically disordered stealth polymers for delivery and methods of using same
FR3045289B1 (fr) 2015-12-17 2021-09-03 Oreal Dispositif de traitement des matieres keratiniques humaines, notamment a l'aide d'un courant electrique
FR3045296B1 (fr) 2015-12-17 2018-01-26 L'oreal Dispositif de traitement des matieres keratiniques humaines, notamment a l'aide d'un courant electrique
FR3045298B1 (fr) 2015-12-17 2018-01-26 L'oreal Appareil de traitement des matieres keratiniques humaines
WO2017112826A2 (en) 2015-12-21 2017-06-29 Duke University Polymer conjugates having reduced antigenicity and methods of using the same
US11752213B2 (en) 2015-12-21 2023-09-12 Duke University Surfaces having reduced non-specific binding and antigenicity
US20170266457A1 (en) * 2016-03-17 2017-09-21 Syneron Medical Ltd. Skin Treatment Method And Apparatus
US11246924B2 (en) 2016-04-01 2022-02-15 Duke University Alpha-helical peptide nanofibers as a self-adjuvanting vaccine platform
KR20240011868A (ko) 2016-04-29 2024-01-26 이노비오 파마수티컬즈, 인크. 제제의 전달을 향상시키기 위한 콘드로이티나제 및/또는 히알루로니다제의 생체내 용도
US11467156B2 (en) 2016-06-01 2022-10-11 Duke University Nonfouling biosensors
US10233419B2 (en) 2016-06-30 2019-03-19 Zymergen Inc. Apparatuses and methods for electroporation
CN109890833A (zh) 2016-09-14 2019-06-14 杜克大学 用于递送亲水性药物的基于三嵌段多肽的纳米粒子
KR20190064600A (ko) 2016-09-23 2019-06-10 듀크 유니버시티 Lcst 거동을 갖는 비구조화된 비-반복적 폴리펩티드
US10376495B2 (en) 2016-11-23 2019-08-13 University Of South Florida Small molecules that mimic or antagonize actions of granulocyte colony-stimulating-factor (G-CSF)
WO2018106344A1 (en) * 2016-12-09 2018-06-14 Gorenshteyn Eduard Methods for cosmetic, galvanic bath-assisted transfer of biologically-active substances
US11648200B2 (en) 2017-01-12 2023-05-16 Duke University Genetically encoded lipid-polypeptide hybrid biomaterials that exhibit temperature triggered hierarchical self-assembly
US10813935B2 (en) 2017-02-23 2020-10-27 Transgenex Nanobiotech, Inc. Methods and compositions for treating drug resistance in cancer
WO2018156989A1 (en) 2017-02-24 2018-08-30 University Of South Florida The hsp90 activator aha1 drives production of pathological tau aggregates
US10272052B2 (en) 2017-02-24 2019-04-30 University Of South Florida Compositions and methods for the treatment of tauopathies
US11554097B2 (en) 2017-05-15 2023-01-17 Duke University Recombinant production of hybrid lipid-biopolymer materials that self-assemble and encapsulate agents
EP3658168A4 (en) 2017-06-30 2021-07-14 Duke University ORDER AND DISORDER AS A DESIGN PRINCIPLE FOR STIMULUS SENSITIVE BIOPOLYMER NETWORKS
GB201710973D0 (en) 2017-07-07 2017-08-23 Avacta Life Sciences Ltd Scaffold proteins
US11441994B2 (en) * 2017-07-27 2022-09-13 Tata Consultancy Services Limited Method and system for in-silico design of skin electroporation
US20190083782A1 (en) * 2017-09-18 2019-03-21 Incube Labs, Llc Iontophoretic systems, kits and methods for transdermal delivery of cosmetic agents
WO2019147954A1 (en) 2018-01-26 2019-08-01 Duke University Albumin binding peptide-drug (aibiped) conjugates and methods of making and using same
US12257308B2 (en) 2018-04-30 2025-03-25 Duke University Stimuli-responsive PEG-like polymer-based drug delivery platform
CN108853720A (zh) * 2018-05-16 2018-11-23 邱骅轩 一种用于美容领域的自适应透皮离子电渗法导入系统
EP3829622A4 (en) 2018-08-02 2022-05-11 Duke University DOUBLE AGONIST FUSION PROTEINS
JP7542202B2 (ja) * 2019-02-27 2024-08-30 パナソニックIpマネジメント株式会社 美容装置
US11512314B2 (en) 2019-07-12 2022-11-29 Duke University Amphiphilic polynucleotides
WO2021074695A1 (en) 2019-10-16 2021-04-22 Avacta Life Sciences Limited PD-L1 INHIBITOR - TGFβ INHIBITOR BISPECIFIC DRUG MOIETIES.
BR112022016507A2 (pt) 2020-02-25 2022-11-22 Inovio Pharmaceuticals Inc Vacinas contra o coronavírus e métodos de uso
KR20230011335A (ko) 2020-05-14 2023-01-20 이노비오 파마수티컬즈, 인크. 재발성 호흡기 유두종증에 대한 백신 및 이의 사용 방법
GB202101299D0 (en) 2020-06-09 2021-03-17 Avacta Life Sciences Ltd Diagnostic polypetides and methods
AU2021289600A1 (en) 2020-06-12 2023-01-19 University Of Rochester Encoding and expression of ACE-tRNAs
WO2022234003A1 (en) 2021-05-07 2022-11-10 Avacta Life Sciences Limited Cd33 binding polypeptides with stefin a protein
FR3123192B1 (fr) * 2021-05-28 2025-04-04 Oreal Procédé d’électroporation pour délivrer une composition comprenant au moins un composé hydroxyacide
FR3123193B1 (fr) * 2021-05-28 2025-11-07 Oreal Procédé d’électroporation pour délivrer une composition comprenant au moins un peptide de poids moléculaire allant de 500 Da à 20 kDa
CN117999364A (zh) 2021-08-13 2024-05-07 艾诺奥医药品有限公司 用以治疗脑癌的组合疗法
EP4412711A1 (en) 2021-10-07 2024-08-14 Avacta Life Sciences Limited Serum half-life extended pd-l1 binding polypeptides
US20250243277A1 (en) 2021-10-07 2025-07-31 Avacta Life Sciences Limited Pd-l1 binding affimers
WO2023150753A1 (en) 2022-02-07 2023-08-10 University Of Rochester Optimized sequences for enhanced trna expression or/and nonsense mutation suppression
CN119213021A (zh) 2022-02-10 2024-12-27 艾菲赛尔治疗株式会社 与CD40L特异性结合的Stefin A蛋白变体及其用途
EP4615869A1 (en) 2022-11-07 2025-09-17 Pinetree Therapeutics, Inc. Combination therapy comprising bispecific antibodies comprising an nrp1 binding domain
EP4634373A1 (en) 2022-12-16 2025-10-22 University of Rochester Repairment of barrier dysfunction in esophagus
WO2025101685A1 (en) 2023-11-09 2025-05-15 University Of Rochester Suppression of nonsense mutations using anticodon engineered (ace)-trnas

Family Cites Families (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2400171A (en) 1935-09-26 1946-05-14 Frances R Ruskin Stabilized metal ascorbates
US2442461A (en) 1944-03-09 1948-06-01 Hoffmann La Roche Stable solutions of calcium ascorbate
US2585580A (en) 1947-06-12 1952-02-12 Opplt Jan Stabilizing ascorbic acid with thio-sugars
DE863111C (de) 1951-07-03 1953-01-15 Walter Hallegger Instrument zur transkutanen und subkutanen Erwaermung und Iontophorese und Verfahrenzu seiner Anwendung
US3163166A (en) * 1961-04-28 1964-12-29 Colgate Palmolive Co Iontophoresis apparatus
DE2800039C2 (de) 1978-01-02 1984-06-20 Horst Dr.Med. 6700 Ludwigshafen Kief Akupunkturgerät
US4367157A (en) 1979-05-10 1983-01-04 Sherman Laboratories, Inc. Soft contact lens ambient temperature disinfectant solution containing ascorbic acid or salt thereof
JPS5810066A (ja) * 1981-07-10 1983-01-20 株式会社アドバンス イオントフオレ−ゼ用プラスタ−構造体
US5421819A (en) 1992-08-12 1995-06-06 Vidamed, Inc. Medical probe device
US4856188A (en) * 1984-10-12 1989-08-15 Drug Delivery Systems Inc. Method for making disposable and/or replenishable transdermal drug applicators
US5224928A (en) * 1983-08-18 1993-07-06 Drug Delivery Systems Inc. Mounting system for transdermal drug applicator
US5042975A (en) * 1986-07-25 1991-08-27 Rutgers, The State University Of New Jersey Iontotherapeutic device and process and iontotherapeutic unit dose
US5749847A (en) 1988-01-21 1998-05-12 Massachusetts Institute Of Technology Delivery of nucleotides into organisms by electroporation
US5547467A (en) 1988-01-21 1996-08-20 Massachusettes Institute Of Technology Method for rapid temporal control of molecular transport across tissue
US5389069A (en) 1988-01-21 1995-02-14 Massachusetts Institute Of Technology Method and apparatus for in vivo electroporation of remote cells and tissue
WO1989006555A1 (en) * 1988-01-21 1989-07-27 Massachusetts Institute Of Technology Transport of molecules across tissue using electroporation
US5108363A (en) * 1988-02-19 1992-04-28 Gensia Pharmaceuticals, Inc. Diagnosis, evaluation and treatment of coronary artery disease by exercise simulation using closed loop drug delivery of an exercise simulating agent beta agonist
EP0346513A1 (de) 1988-06-15 1989-12-20 Etama Ag Anordnung zur Elektrotherapie
ES2012944A6 (es) 1989-01-09 1990-04-16 Tomas Justribo Jose Ramon Procedimiento y su dispositivo para la admionistracion de farmacos mediante ionoforesis, para tratamiento loco-regionales.
CS275292B2 (en) 1989-02-22 1992-02-19 Cvut Fakulta Elektrotechnick Private rehabilitation apparatus with ion transcutaneous acceleration
US5135478A (en) * 1989-05-10 1992-08-04 Drug Delivery Systems Inc. Multi-signal electrical transdermal drug applicator
US6001617A (en) 1989-06-07 1999-12-14 Queen's University At Kingston Electroporation device and method of use
EP0429842B1 (en) * 1989-10-27 1996-08-28 Korea Research Institute Of Chemical Technology Device for the transdermal administration of protein or peptide drug
US5215088A (en) 1989-11-07 1993-06-01 The University Of Utah Three-dimensional electrode device
DE4000893A1 (de) 1990-01-15 1991-07-18 Bosch Gmbh Robert Mehrkanaliges geraet zur elektrostimulation
US5137817A (en) * 1990-10-05 1992-08-11 Amoco Corporation Apparatus and method for electroporation
US5279544A (en) * 1990-12-13 1994-01-18 Sil Medics Ltd. Transdermal or interdermal drug delivery devices
US5328451A (en) 1991-08-15 1994-07-12 Board Of Regents, The University Of Texas System Iontophoretic device and method for killing bacteria and other microbes
PT101031B (pt) 1991-11-05 2002-07-31 Transkaryotic Therapies Inc Processo para o fornecimento de proteinas por terapia genetica
US5425752A (en) 1991-11-25 1995-06-20 Vu'nguyen; Dung D. Method of direct electrical myostimulation using acupuncture needles
US5304120A (en) 1992-07-01 1994-04-19 Btx Inc. Electroporation method and apparatus for insertion of drugs and genes into endothelial cells
US5507724A (en) 1992-07-01 1996-04-16 Genetronics, Inc. Electroporation and iontophoresis apparatus and method for insertion of drugs and genes into cells
US5514131A (en) 1992-08-12 1996-05-07 Stuart D. Edwards Method for the ablation treatment of the uvula
US5273525A (en) 1992-08-13 1993-12-28 Btx Inc. Injection and electroporation apparatus for drug and gene delivery
US5688233A (en) * 1992-08-17 1997-11-18 Genetronics, Inc. Electronincorporation enhanced transdermal delivery of molecules
US5464386A (en) * 1992-08-17 1995-11-07 Genetronics, Inc. Transdermal drug delivery by electroincorporation of vesicles
US5468223A (en) 1992-11-30 1995-11-21 C.N.R.S. Paris Electrochemotherapy
JPH08506259A (ja) 1993-02-02 1996-07-09 ヴィーダメッド インコーポレイテッド 経尿道ニードル切除装置および方法
FR2703253B1 (fr) 1993-03-30 1995-06-23 Centre Nat Rech Scient Applicateur d'impulsions electriques pour traitement de tissus biologiques.
US5439440A (en) 1993-04-01 1995-08-08 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US5993434A (en) 1993-04-01 1999-11-30 Genetronics, Inc. Method of treatment using electroporation mediated delivery of drugs and genes
US5702359A (en) 1995-06-06 1997-12-30 Genetronics, Inc. Needle electrodes for mediated delivery of drugs and genes
US5667487A (en) * 1993-04-07 1997-09-16 Henley; Julian L. Ionosonic drug delivery apparatus
WO1994027670A1 (en) 1993-06-02 1994-12-08 Cardiac Pathways Corporation Catheter having tip with fixation means
US5536267A (en) 1993-11-08 1996-07-16 Zomed International Multiple electrode ablation apparatus
US5445611A (en) * 1993-12-08 1995-08-29 Non-Invasive Monitoring Company (Nimco) Enhancement of transdermal delivery with ultrasound and chemical enhancers
US5814599A (en) 1995-08-04 1998-09-29 Massachusetts Insitiute Of Technology Transdermal delivery of encapsulated drugs
IL108775A (en) 1994-02-25 2003-09-17 Univ Ramot Method for efficient incorporation of molecules into cells
US5728094A (en) 1996-02-23 1998-03-17 Somnus Medical Technologies, Inc. Method and apparatus for treatment of air way obstructions
US5786454A (en) 1994-09-16 1998-07-28 Washington University School Of Medicine Modified SH2 domains
US5720921A (en) 1995-03-10 1998-02-24 Entremed, Inc. Flow electroporation chamber and method
US5868740A (en) 1995-03-24 1999-02-09 Board Of Regents-Univ Of Nebraska Method for volumetric tissue ablation
US5810762A (en) 1995-04-10 1998-09-22 Genetronics, Inc. Electroporation system with voltage control feedback for clinical applications
US5780052A (en) 1995-04-24 1998-07-14 Northeastern University Compositions and methods useful for inhibiting cell death and for delivering an agent into a cell
US5789213A (en) 1995-05-11 1998-08-04 Health Research Inc. Method and compositions for high efficiency loading, transfection and fusion of cells by electric pulses
US6002961A (en) 1995-07-25 1999-12-14 Massachusetts Institute Of Technology Transdermal protein delivery using low-frequency sonophoresis
US5983131A (en) 1995-08-11 1999-11-09 Massachusetts Institute Of Technology Apparatus and method for electroporation of tissue
US5980517A (en) 1995-08-15 1999-11-09 Rita Medical Systems, Inc. Cell necrosis apparatus
AU6855796A (en) 1995-08-29 1997-03-19 Cbr Laboratories, Inc. In vivo electroporation of cells
US6283951B1 (en) * 1996-10-11 2001-09-04 Transvascular, Inc. Systems and methods for delivering drugs to selected locations within the body
US5676648A (en) * 1996-05-08 1997-10-14 The Aps Organization, Llp Iontophoretic drug delivery apparatus and method for use
WO1997047355A1 (en) 1996-06-12 1997-12-18 Alza Corporation Reduction of skin sensitization in electrotransport drug delivery
GB2314274A (en) 1996-06-20 1997-12-24 Gyrus Medical Ltd Electrode construction for an electrosurgical instrument
US5911223A (en) 1996-08-09 1999-06-15 Massachusetts Institute Of Technology Introduction of modifying agents into skin by electroporation
US5869326A (en) 1996-09-09 1999-02-09 Genetronics, Inc. Electroporation employing user-configured pulsing scheme
US5874268A (en) 1996-09-23 1999-02-23 Duke University Method of introducing exogenous compounds into cells by electroporation and apparatus for same
US5908753A (en) 1996-10-04 1999-06-01 Merck & Co., Inc. Transformation of Candida albicans by electroporation
US5845646A (en) 1996-11-05 1998-12-08 Lemelson; Jerome System and method for treating select tissue in a living being
US5873849A (en) 1997-04-24 1999-02-23 Ichor Medical Systems, Inc. Electrodes and electrode arrays for generating electroporation inducing electrical fields
US5879891A (en) 1997-09-17 1999-03-09 Merck & Co., Inc. Transformation of saccharomyces cerevisiae by electroporation
TW368420B (en) 1997-11-04 1999-09-01 Genetronics Inc Apparatus and method for transdermal molecular delivery by applying sufficient amplitude of electric field to induce migration of molecules through pores in the stratum corneum
US6022316A (en) 1998-03-06 2000-02-08 Spectrx, Inc. Apparatus and method for electroporation of microporated tissue for enhancing flux rates for monitoring and delivery applications
JP2003511098A (ja) 1998-04-14 2003-03-25 ジーエムピー・ドラツグ・デリバリー・インコーポレーテツド 動脈及び他の身体組織への局所的薬物移送のためのイオン導入、エレクトロポレーション及び組み合わせカテーテル
AU761522B2 (en) * 1998-07-13 2003-06-05 Genetronics, Inc. Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications
US6192270B1 (en) 1998-08-14 2001-02-20 Genetronics, Inc. Apparatus and method for the delivery of drugs and genes into tissue

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007521258A (ja) * 2003-06-23 2007-08-02 トランスファーマ メディカル リミテッド 化粧剤用経皮送達システム
JP2011519640A (ja) * 2008-05-09 2011-07-14 フェンジアン・リミテッド 患者の健康の回復に用いる複数の電子
JP2011041705A (ja) * 2009-08-21 2011-03-03 Kyushu Hitachi Maxell Ltd 美容装置
JP2013158441A (ja) * 2012-02-03 2013-08-19 Hitachi Maxell Ltd 唇用美容器具、および唇の美容方法
JP2020137720A (ja) * 2019-02-27 2020-09-03 パナソニックIpマネジメント株式会社 美容装置およびその経路形成機構
JP7241300B2 (ja) 2019-02-27 2023-03-17 パナソニックIpマネジメント株式会社 美容装置およびその経路形成機構

Also Published As

Publication number Publication date
EP1102608A1 (en) 2001-05-30
US20030097118A1 (en) 2003-05-22
US6302874B1 (en) 2001-10-16
EP1102608A4 (en) 2008-09-17
AU4988299A (en) 2000-02-01
CA2337129A1 (en) 2000-01-20
WO2000002620A1 (en) 2000-01-20
US6947791B2 (en) 2005-09-20
AU761522B2 (en) 2003-06-05

Similar Documents

Publication Publication Date Title
AU761522B2 (en) Method and apparatus for electrically assisted topical delivery of agents for cosmetic applications
JP4394444B2 (ja) 活性物質の制御された皮膚内デリバリーのためのデバイス及び方法
Zhang et al. Electroporation-mediated topical delivery of vitamin C for cosmetic applications
Xu et al. Effects of electrical stimulation on skin surface
CN101072602B (zh) 用于电抑制面部肌肉的装置
RU2372113C2 (ru) Способ, устройство и набор для лечения онихомикоза с использованием электрокинетического переноса веществ
US5158081A (en) Method for treatment of soft tissue wounds by electrical stimulation
US20030233085A1 (en) Optimization of transcutaneous active permeation of compounds through the synergistic use of ultrasonically generated mechanical abrasion of the skin, chemical enhancers and simultaneous application of sonophoresis, iontophoresis, electroporation, mechanical vibrations and magnetophoresis through single application devices
WO1997027899A9 (en) Iontophoretic treatment system
CA2243525A1 (en) Iontophoretic treatment system
KR102392502B1 (ko) 교차전극형 마이크로 니들 패치
WO2007092796A2 (en) Galvanic current skin treatment
US20060264805A1 (en) Permeabilization of biological membranes
AU2020369800B2 (en) Iontophoresis administration device
WO2001080945A1 (en) Method for transdermal administration of ascorbic acid
US6139537A (en) Iontophoretic treatment system
US6235013B1 (en) Iontophoretic treatment system
WO1999051296A1 (en) Ultrasound enhancement of percutaneous drug absorption
WO2024218387A1 (en) Use of charged air ions in cosmetic treatments
Tamarkin Using iontophoresis to enhance cosmetics delivery
KR20230091270A (ko) 미세전류를 활용해 피부세포를 자극함으로써 안티에이징 효과를 극대화한 콜라겐 생성 휴대용 미용기기
Sun et al. Bioelectricity and Its Application in Cosmetic Dermatology

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20060609

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20060706

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20071211

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20080305

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20080312

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080611

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20080715

A601 Written request for extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A601

Effective date: 20081009

A602 Written permission of extension of time

Free format text: JAPANESE INTERMEDIATE CODE: A602

Effective date: 20081017

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20090210