JP2002518354A - 糖硫酸ペプチド、その合成方法および使用方法 - Google Patents
糖硫酸ペプチド、その合成方法および使用方法Info
- Publication number
- JP2002518354A JP2002518354A JP2000554568A JP2000554568A JP2002518354A JP 2002518354 A JP2002518354 A JP 2002518354A JP 2000554568 A JP2000554568 A JP 2000554568A JP 2000554568 A JP2000554568 A JP 2000554568A JP 2002518354 A JP2002518354 A JP 2002518354A
- Authority
- JP
- Japan
- Prior art keywords
- glcnac
- binding
- amino acid
- gal
- peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8947298P | 1998-06-16 | 1998-06-16 | |
| US60/089,472 | 1998-06-16 | ||
| PCT/US1999/013455 WO1999065712A2 (en) | 1998-06-16 | 1999-06-15 | Glycosulfopeptides and methods of synthesis and use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002518354A true JP2002518354A (ja) | 2002-06-25 |
| JP2002518354A5 JP2002518354A5 (https=) | 2006-08-10 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000554568A Withdrawn JP2002518354A (ja) | 1998-06-16 | 1999-06-15 | 糖硫酸ペプチド、その合成方法および使用方法 |
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| Country | Link |
|---|---|
| US (4) | US6593459B1 (https=) |
| EP (1) | EP1087996B1 (https=) |
| JP (1) | JP2002518354A (https=) |
| AU (1) | AU773542B2 (https=) |
| CA (1) | CA2332563A1 (https=) |
| DE (1) | DE69934890D1 (https=) |
| MX (1) | MXPA00012586A (https=) |
| WO (1) | WO1999065712A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007524693A (ja) * | 2004-02-20 | 2007-08-30 | ザ バーナム インスティチュート | 抗菌性の糖質及びそれを用いた方法 |
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| US20030143662A1 (en) * | 1998-06-16 | 2003-07-31 | Cummings Richard D. | Glycosulfopeptide inhibitors of leukocyte rolling and methods of use thereof |
| DE69934890D1 (de) * | 1998-06-16 | 2007-03-08 | Univ Oklahoma | Glykosulfopeptide und verfahren zu deren herstellung und deren verwendung |
| US7223845B2 (en) | 1998-06-16 | 2007-05-29 | The Board Of Regents Of The University Of Oklahoma | Synthetic glycosulfopeptides and methods of synthesis thereof |
| US6492152B1 (en) | 1999-06-15 | 2002-12-10 | The Board Of Regents Of The University Of Oklahoma | Core 1 β3-galactosyl transferases and methods of use thereof |
| MXPA02005953A (es) * | 1999-12-15 | 2003-01-28 | Univ Oklahoma | Beta 3-galactosil transferasas de nucleo 1 y metodos de uso de las mismas. |
| EP1325123A4 (en) * | 2000-09-12 | 2004-07-21 | Inst Genetics Llc | STENOSE- OR RESEARCH INHIBITION BY P-SELECTIN ANTAGONISTS |
| SE0004828D0 (sv) * | 2000-12-22 | 2000-12-22 | Pharmacia Ab | Protein cluster II |
| US20040001839A1 (en) * | 2000-12-29 | 2004-01-01 | Avigdor Levanon | Multimers - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US7132510B2 (en) * | 2000-12-29 | 2006-11-07 | Bio-Technology General (Israel) Ltd. | Specific human antibodies for selective cancer therapy |
| US20040002450A1 (en) * | 2000-12-29 | 2004-01-01 | Janette Lazarovits | Y17 - isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| CA2433225A1 (en) * | 2000-12-29 | 2002-07-11 | Bio-Technology General, Inc. | Isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US20040001822A1 (en) * | 2000-12-29 | 2004-01-01 | Avigdor Levanon | Y1-isolated molecules comprising epitopes containing sulfated moieties, antibodies to such epitopes, and uses thereof |
| US6537780B2 (en) * | 2001-03-28 | 2003-03-25 | Applera Corporation | Isolated nucleic acid molecules encoding transferase enzymes |
| WO2003032925A2 (en) * | 2001-10-19 | 2003-04-24 | Cummings Richard D | Glycosulfopeptide inhibitors and methods of use thereof |
| JP5183010B2 (ja) * | 2002-05-16 | 2013-04-17 | グリコミメティクス， インコーポレイテッド | セレクチンによって媒介される機能を阻害するための化合物および方法 |
| US20040202665A1 (en) * | 2002-07-01 | 2004-10-14 | Janette Lazarovits | Compositions and methods for therapeutic treatment |
| CA2490703A1 (en) * | 2002-07-03 | 2004-01-15 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving angiogenesis |
| US20040219158A1 (en) * | 2003-05-02 | 2004-11-04 | Glycomimetics, Inc. | Compositions and methods for diagnosis and therapy of medical conditions involving infection with pseudomonas bacteria |
| US20050266009A1 (en) * | 2003-06-30 | 2005-12-01 | Savient Pharmaceuticals, Inc. | Antibodies and uses thereof |
| US20050152906A1 (en) * | 2003-06-30 | 2005-07-14 | Avigdor Levanon | Specific human antibodies |
| US20050069955A1 (en) * | 2003-06-30 | 2005-03-31 | Daniel Plaksin | Antibodies and uses thereof |
| WO2005051920A2 (en) * | 2003-11-19 | 2005-06-09 | Glycomimetics, Inc. | Specific antagonist for both e- and p-selectins |
| US20050187171A1 (en) * | 2003-11-19 | 2005-08-25 | Glycomimetics, Inc. | Glycomimetic antagonists for both E-and P-selectins |
| US8201377B2 (en) * | 2004-11-05 | 2012-06-19 | Faus Group, Inc. | Flooring system having multiple alignment points |
| TWI264608B (en) * | 2005-04-08 | 2006-10-21 | Delta Electronics Inc | Light tunnel module |
| US20090036386A1 (en) * | 2005-05-25 | 2009-02-05 | Glycomimetics, Inc | Heterobifunctional compounds for selectin inhibition |
| EP1928892B1 (en) * | 2005-08-09 | 2011-10-12 | GlycoMimetics, Inc. | Glycomimetic inhibitors of the pa-il lectin, pa-iil lectin or both the lectins from pseudomonas |
| SI2264043T1 (en) | 2005-09-02 | 2018-01-31 | Glycomimetics, Inc. | HETEROBIFUNCTIONAL PAN-SELECTINE INHIBITORS |
| WO2007143052A1 (en) * | 2006-06-01 | 2007-12-13 | Glycomimetics, Inc. | Galactosides and thiodigalactosides as inhibitors of pa-il lectin from pseudomonas |
| WO2008060378A2 (en) | 2006-10-12 | 2008-05-22 | Glycomimetics, Inc. | Glycomimetic replacements for hexoses and n-acetyl hexosamines |
| AU2008216794A1 (en) * | 2007-02-09 | 2008-08-21 | Glycomimetics, Inc. | Methods of use of glycomimetics with replacements for hexoses and N-acetyl hexosamines |
| US8039442B2 (en) * | 2007-07-18 | 2011-10-18 | Glycomimetics, Inc. | Compounds and methods for treatment of sickle cell disease or complications associated therewith |
| AU2008336249B2 (en) | 2007-12-10 | 2015-01-29 | The University Of Queensland | Treatment and prophylaxis |
| WO2009126556A1 (en) * | 2008-04-08 | 2009-10-15 | Glycomimetics, Inc. | Pan-selectin inhibitor with enhanced pharmacokinetic activity |
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| CN111566117A (zh) | 2017-12-29 | 2020-08-21 | 糖模拟物有限公司 | E-选择蛋白和半乳凝素-3的异双功能抑制剂 |
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| CN113646427A (zh) | 2019-01-15 | 2021-11-12 | 奥普蒂姆维亚有限公司 | 工程化芳基硫酸酯依赖性酶 |
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| WO1991016449A1 (en) | 1990-04-16 | 1991-10-31 | The Trustees Of The University Of Pennsylvania | Saccharide compositions, methods and apparatus for their synthesis |
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| SE504074C2 (sv) * | 1993-07-05 | 1996-11-04 | Pharmacia Ab | Proteinberedning för subkutan, intramuskulär eller intradermal administrering |
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1999
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2002
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007524693A (ja) * | 2004-02-20 | 2007-08-30 | ザ バーナム インスティチュート | 抗菌性の糖質及びそれを用いた方法 |
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| AU773542B2 (en) | 2004-05-27 |
| EP1087996B1 (en) | 2007-01-17 |
| US20030144183A1 (en) | 2003-07-31 |
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| CA2332563A1 (en) | 1999-12-23 |
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| US20020042102A1 (en) | 2002-04-11 |
| WO1999065712A3 (en) | 2000-04-20 |
| WO1999065712A2 (en) | 1999-12-23 |
| MXPA00012586A (es) | 2004-05-21 |
| EP1087996A2 (en) | 2001-04-04 |
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