JP2002518016A - Ｎｅｋ関連及びｂｕｂ１関連プロテインキナーゼ - Google Patents

Ｎｅｋ関連及びｂｕｂ１関連プロテインキナーゼ

Info

Publication number
JP2002518016A
JP2002518016A JP2000554860A JP2000554860A JP2002518016A JP 2002518016 A JP2002518016 A JP 2002518016A JP 2000554860 A JP2000554860 A JP 2000554860A JP 2000554860 A JP2000554860 A JP 2000554860A JP 2002518016 A JP2002518016 A JP 2002518016A
Authority
JP
Japan
Prior art keywords
seq
amino acid
kinase
acid sequence
kinase polypeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000554860A
Other languages
English (en)
Japanese (ja)
Other versions
JP2002518016A5 (enExample
Inventor
グレゴリー プラウマン
リカルド マルティネス
インファン チュ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sugen LLC
Original Assignee
Sugen LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sugen LLC filed Critical Sugen LLC
Publication of JP2002518016A publication Critical patent/JP2002518016A/ja
Publication of JP2002518016A5 publication Critical patent/JP2002518016A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • Psychiatry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
JP2000554860A 1998-06-16 1999-06-15 Ｎｅｋ関連及びｂｕｂ１関連プロテインキナーゼ Withdrawn JP2002518016A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US8952098P 1998-06-16 1998-06-16
US60/089,520 1998-06-16
US9826598P 1998-08-28 1998-08-28
US60/098,265 1998-08-28
PCT/US1999/013533 WO1999066051A2 (en) 1998-06-16 1999-06-15 Nek-related and bub1-related protein kinases

Publications (2)

Publication Number Publication Date
JP2002518016A true JP2002518016A (ja) 2002-06-25
JP2002518016A5 JP2002518016A5 (enExample) 2006-07-20

Family

ID=26780662

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000554860A Withdrawn JP2002518016A (ja) 1998-06-16 1999-06-15 Ｎｅｋ関連及びｂｕｂ１関連プロテインキナーゼ

Country Status (5)

Country Link
EP (1) EP1088079A2 (enExample)
JP (1) JP2002518016A (enExample)
AU (1) AU4686299A (enExample)
CA (1) CA2331889A1 (enExample)
WO (1) WO1999066051A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016514717A (ja) * 2013-03-21 2016-05-23 バイエル ファーマ アクチエンゲゼルシャフト ジアミノヘテロアリール置換インダゾール

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6183962B1 (en) * 1998-09-09 2001-02-06 Millennium Pharmaceuticals, Inc. Protein kinase molecules and uses therefor
WO2001096544A2 (en) * 2000-06-15 2001-12-20 Millennium Pharmaceuticals, Inc. 53070, a novel human protein kinase family member and uses thereof
DE10011530A1 (de) * 2000-03-13 2001-09-27 Robert Elez Hochwirksame Antisense-Oligodesoxynucleotide gegen Polio-like Kinasel
WO2002003790A2 (en) * 2000-07-11 2002-01-17 Deltagen, Inc. Transgenic mice containing targeted kinase gene disruptions
AU2002214576A1 (en) * 2000-10-13 2002-04-22 The Government Of The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Genes related to development of refractory prostate cancer
US7033790B2 (en) 2001-04-03 2006-04-25 Curagen Corporation Proteins and nucleic acids encoding same
US20040097441A1 (en) * 2002-11-16 2004-05-20 Isis Pharmaceuticals Inc. Modulation of NIMA-related kinase 6 expression
EP1554578A2 (en) * 2002-06-11 2005-07-20 The General Hospital Corporation Identification of inhibitors of mitosis

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5863780A (en) * 1996-09-12 1999-01-26 Incyte Pharmaceuticals, Inc. Human Protein Kinases
AU7828698A (en) * 1997-06-11 1998-12-30 Chiron Corporation Detection of loss of the wild-type (hu)bub1 gene
US6593098B1 (en) * 1997-12-01 2003-07-15 Fox Chase Cancer Center Genes encoding proteins involved in mitotic checkpoint control and methods of use thereof
WO1999047638A2 (en) * 1998-03-16 1999-09-23 The Johns Hopkins University School Of Medicine Mutations in mitotic check point genes and methods of diagnosis
US5928874A (en) * 1998-03-27 1999-07-27 Incyte Pharmaceuticals, Inc. Nek1-related protein kinase
WO1999055865A1 (en) * 1998-04-29 1999-11-04 Genesis Research And Development Corporation Limited Polynucleotides isolated from skin cells and methods for their use
EP1027441A2 (en) * 1998-08-04 2000-08-16 Immunex Corporation Murine dna molecules encoding polypeptides having kinase functions

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2016514717A (ja) * 2013-03-21 2016-05-23 バイエル ファーマ アクチエンゲゼルシャフト ジアミノヘテロアリール置換インダゾール

Also Published As

Publication number Publication date
AU4686299A (en) 2000-01-05
EP1088079A2 (en) 2001-04-04
WO1999066051A3 (en) 2000-06-15
WO1999066051A2 (en) 1999-12-23
CA2331889A1 (en) 1999-12-23

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