JP2002517185A - 前立腺癌および結腸癌の診断および治療に有用な腫瘍抗原 - Google Patents
前立腺癌および結腸癌の診断および治療に有用な腫瘍抗原Info
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- JP2002517185A JP2002517185A JP2000552152A JP2000552152A JP2002517185A JP 2002517185 A JP2002517185 A JP 2002517185A JP 2000552152 A JP2000552152 A JP 2000552152A JP 2000552152 A JP2000552152 A JP 2000552152A JP 2002517185 A JP2002517185 A JP 2002517185A
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- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
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- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
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| PCT/US1999/012253 WO1999062942A2 (en) | 1998-06-01 | 1999-06-01 | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
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| JP2008330218A Pending JP2009148265A (ja) | 1998-06-01 | 2008-12-25 | 前立腺癌および結腸癌の診断および治療に有用な腫瘍抗原 |
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| US7037667B1 (en) * | 1998-06-01 | 2006-05-02 | Agensys, Inc. | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
| EP1117794A2 (en) * | 1998-10-02 | 2001-07-25 | Urogenesys, Inc. | Human gene expressed in cancers of prostate, bladder, pancreas and colon, 36p1a6 |
| JP2002527758A (ja) * | 1998-10-19 | 2002-08-27 | ダイアデクスアス・インコーポレーテッド | 前立腺癌を診断、監視、病期分類、イメージング及び治療する方法 |
| US6902892B1 (en) | 1998-10-19 | 2005-06-07 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| WO2000065067A2 (en) * | 1999-04-23 | 2000-11-02 | University Of Washington | Prostate-specific polynucleotides, polypeptides and their methods of use |
| AU774436B2 (en) | 1999-08-12 | 2004-06-24 | Agensys, Inc. | C-type lectin transmembrane antigen expressed in human prostate cancer and uses thereof |
| US20020040127A1 (en) * | 2000-06-09 | 2002-04-04 | Yuqiu Jiang | Compositions and methods for the therapy and diagnosis of colon cancer |
| EP1294903B1 (en) | 2000-06-13 | 2008-05-07 | Bayer HealthCare AG | Regulation of human transmembrane serine protease |
| EP2075582A3 (en) * | 2000-07-12 | 2010-01-06 | Agensys, Inc. | Novel tumor antigen useful in diagnosis and therapy of bladder, ovary, lung and kidney cancers |
| US6743592B1 (en) * | 2000-07-25 | 2004-06-01 | The Trustees Of The University Of Pennsylvania | Methods, systems and kits for immuno-detection of epitopes expressed on molecules |
| US20040018973A1 (en) | 2002-01-25 | 2004-01-29 | University Of Pittsburgh | Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof |
| WO2004092397A2 (en) * | 2003-04-15 | 2004-10-28 | Novartis Ag | Tmprss2 regulatory sequences and uses thereof |
| WO2004097358A2 (en) * | 2003-05-02 | 2004-11-11 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human transmembrane serine protease 2 (tmprss2) |
| US9957569B2 (en) | 2005-09-12 | 2018-05-01 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| EP2612870A1 (en) | 2005-09-12 | 2013-07-10 | The Regents of the University of Michigan | Recurrent gene fusions in prostate cancer |
| WO2008119767A2 (en) * | 2007-03-30 | 2008-10-09 | Oryzon Genomics, S. A. | Method of nucleic acid analysis. |
| AU2008275303B2 (en) | 2007-07-06 | 2012-05-03 | The Regents Of The University Of Michigan | MIPOL1-ETV1 gene rearrangements |
| WO2009020521A2 (en) | 2007-08-03 | 2009-02-12 | The Brigham And Women's Hospital, Inc. | Identification and treatment of estrogen responsive prostate tumors |
| CN102712953A (zh) | 2009-09-17 | 2012-10-03 | 密歇根大学董事会 | 前列腺癌中的复发性基因融合物 |
| US8945556B2 (en) | 2010-11-19 | 2015-02-03 | The Regents Of The University Of Michigan | RAF gene fusions |
| BR112014018005B1 (pt) * | 2012-02-15 | 2021-06-29 | F. Hoffmann-La Roche Ag | Uso de um complexo não covalente imobilizado |
| PT3215528T (pt) | 2014-11-06 | 2019-10-11 | Hoffmann La Roche | Variantes da região fc com ligação modificada ao fcrn e métodos de utilização |
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| WO1989006692A1 (en) * | 1988-01-12 | 1989-07-27 | Genentech, Inc. | Method of treating tumor cells by inhibiting growth factor receptor function |
| US5288612A (en) * | 1991-07-03 | 1994-02-22 | The Scripps Research Institute | Assay methods for detecting serum proteases, particularly activated protein C |
| JP3149185B2 (ja) * | 1993-01-15 | 2001-03-26 | ジェネティックス・インスティテュート・インコーポレイテッド | エンテロキナーゼのクローニングおよび使用方法 |
| US6800746B2 (en) * | 1997-02-25 | 2004-10-05 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
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1999
- 1999-06-01 AT AT99927164T patent/ATE490977T1/de active
- 1999-06-01 EP EP99927164A patent/EP1082341B1/en not_active Expired - Lifetime
- 1999-06-01 CA CA2329137A patent/CA2329137C/en not_active Expired - Fee Related
- 1999-06-01 DE DE69943020T patent/DE69943020D1/de not_active Expired - Lifetime
- 1999-06-01 IL IL13998899A patent/IL139988A0/xx not_active IP Right Cessation
- 1999-06-01 AU AU44136/99A patent/AU773187B2/en not_active Ceased
- 1999-06-01 PT PT99927164T patent/PT1082341E/pt unknown
- 1999-06-01 DK DK99927164.6T patent/DK1082341T3/da active
- 1999-06-01 JP JP2000552152A patent/JP2002517185A/ja not_active Withdrawn
- 1999-06-01 WO PCT/US1999/012253 patent/WO1999062942A2/en not_active Ceased
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2004
- 2004-05-25 AU AU2004202306A patent/AU2004202306C1/en not_active Ceased
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2005
- 2005-08-09 US US11/200,973 patent/US20060275304A1/en not_active Abandoned
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2008
- 2008-12-25 JP JP2008330218A patent/JP2009148265A/ja active Pending
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2011
- 2011-03-08 CY CY20111100264T patent/CY1111906T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1082341T3 (da) | 2011-03-28 |
| CY1111906T1 (el) | 2015-11-04 |
| WO1999062942A2 (en) | 1999-12-09 |
| AU4413699A (en) | 1999-12-20 |
| ATE490977T1 (de) | 2010-12-15 |
| EP1082341B1 (en) | 2010-12-08 |
| PT1082341E (pt) | 2011-02-15 |
| EP1082341A2 (en) | 2001-03-14 |
| AU2004202306A1 (en) | 2004-06-24 |
| CA2329137A1 (en) | 1999-12-09 |
| US20060275304A1 (en) | 2006-12-07 |
| IL139988A0 (en) | 2002-02-10 |
| CA2329137C (en) | 2011-09-20 |
| JP2009148265A (ja) | 2009-07-09 |
| AU2004202306B2 (en) | 2007-05-24 |
| WO1999062942A3 (en) | 2000-06-02 |
| AU773187B2 (en) | 2004-05-20 |
| AU2004202306C1 (en) | 2008-05-01 |
| DE69943020D1 (de) | 2011-01-20 |
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