ATE490977T1 - Tumorantigen verwendbar in der diagnose und therapie von prostata und dickdarm-krebs - Google Patents
Tumorantigen verwendbar in der diagnose und therapie von prostata und dickdarm-krebsInfo
- Publication number
- ATE490977T1 ATE490977T1 AT99927164T AT99927164T ATE490977T1 AT E490977 T1 ATE490977 T1 AT E490977T1 AT 99927164 T AT99927164 T AT 99927164T AT 99927164 T AT99927164 T AT 99927164T AT E490977 T1 ATE490977 T1 AT E490977T1
- Authority
- AT
- Austria
- Prior art keywords
- prostate
- tmprss2
- diagnosis
- therapy
- colon cancer
- Prior art date
Links
- 210000002307 prostate Anatomy 0.000 title abstract 3
- 206010009944 Colon cancer Diseases 0.000 title abstract 2
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 title abstract 2
- 208000029742 colonic neoplasm Diseases 0.000 title abstract 2
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 238000002560 therapeutic procedure Methods 0.000 title abstract 2
- 206010028980 Neoplasm Diseases 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 101000638154 Homo sapiens Transmembrane protease serine 2 Proteins 0.000 abstract 4
- 102100031989 Transmembrane protease serine 2 Human genes 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108010022999 Serine Proteases Proteins 0.000 abstract 1
- 102000012479 Serine Proteases Human genes 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000002299 complementary DNA Substances 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 239000003550 marker Substances 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 230000001105 regulatory effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 239000003053 toxin Substances 0.000 abstract 1
- 231100000765 toxin Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Urology & Nephrology (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8759898P | 1998-06-01 | 1998-06-01 | |
| US9147498P | 1998-06-29 | 1998-06-29 | |
| US12952199P | 1999-04-14 | 1999-04-14 | |
| PCT/US1999/012253 WO1999062942A2 (en) | 1998-06-01 | 1999-06-01 | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE490977T1 true ATE490977T1 (de) | 2010-12-15 |
Family
ID=27375711
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99927164T ATE490977T1 (de) | 1998-06-01 | 1999-06-01 | Tumorantigen verwendbar in der diagnose und therapie von prostata und dickdarm-krebs |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US20060275304A1 (de) |
| EP (1) | EP1082341B1 (de) |
| JP (2) | JP2002517185A (de) |
| AT (1) | ATE490977T1 (de) |
| AU (2) | AU773187B2 (de) |
| CA (1) | CA2329137C (de) |
| CY (1) | CY1111906T1 (de) |
| DE (1) | DE69943020D1 (de) |
| DK (1) | DK1082341T3 (de) |
| IL (1) | IL139988A0 (de) |
| PT (1) | PT1082341E (de) |
| WO (1) | WO1999062942A2 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7037667B1 (en) * | 1998-06-01 | 2006-05-02 | Agensys, Inc. | Tumor antigen useful in diagnosis and therapy of prostate and colon cancer |
| CA2344552A1 (en) * | 1998-10-02 | 2000-04-13 | Urogenesys, Inc. | Human gene expressed in cancers of prostate, bladder, pancreas and colon, 36p1a6 |
| WO2000023111A1 (en) * | 1998-10-19 | 2000-04-27 | Diadexus Llc | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| US6902892B1 (en) | 1998-10-19 | 2005-06-07 | Diadexus, Inc. | Method of diagnosing, monitoring, staging, imaging and treating prostate cancer |
| AU4484400A (en) * | 1999-04-23 | 2000-11-10 | University Of Washington | Prostate-specific polynucleotides, polypeptides and their methods of use |
| ES2317846T3 (es) | 1999-08-12 | 2009-05-01 | Agensys, Inc. | Antigeno transmembranal de lectina tipo c en el cancer de prostata humano y usos del mismo. |
| AU2001269766A1 (en) * | 2000-06-09 | 2001-12-24 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of colon cancer |
| ATE394491T1 (de) | 2000-06-13 | 2008-05-15 | Bayer Healthcare Ag | Regulierung einer humanen transmembran- serinprotease |
| ATE429643T1 (de) * | 2000-07-12 | 2009-05-15 | Agensys Inc | Neues tumor antigen das für diagnose und therapie von blasen-, eierstock-, lungen- und nierenkrebs verwendet werden kann |
| US6743592B1 (en) * | 2000-07-25 | 2004-06-01 | The Trustees Of The University Of Pennsylvania | Methods, systems and kits for immuno-detection of epitopes expressed on molecules |
| US20040018973A1 (en) | 2002-01-25 | 2004-01-29 | University Of Pittsburgh | Nuclear matrix protein alterations associated with colon cancer and colon metastasis to the liver, and uses thereof |
| WO2004092397A2 (en) * | 2003-04-15 | 2004-10-28 | Novartis Ag | Tmprss2 regulatory sequences and uses thereof |
| WO2004097358A2 (en) * | 2003-05-02 | 2004-11-11 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with human transmembrane serine protease 2 (tmprss2) |
| CA2622295C (en) | 2005-09-12 | 2019-01-15 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| US9957569B2 (en) | 2005-09-12 | 2018-05-01 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| EP2140022A2 (de) * | 2007-03-30 | 2010-01-06 | Oryzon Genomics, S.A. | Nukleinsäureanalyseverfahren |
| ATE533861T1 (de) | 2007-07-06 | 2011-12-15 | Univ Michigan | Mipol1-etv1-gen-neuanordnungen |
| US8106037B2 (en) | 2007-08-03 | 2012-01-31 | The Brigham And Women's Hospital, Inc. | Identification and treatment of estrogen responsive prostate tumors |
| WO2011034906A2 (en) | 2009-09-17 | 2011-03-24 | The Regents Of The University Of Michigan | Recurrent gene fusions in prostate cancer |
| US8945556B2 (en) | 2010-11-19 | 2015-02-03 | The Regents Of The University Of Michigan | RAF gene fusions |
| WO2013120929A1 (en) * | 2012-02-15 | 2013-08-22 | F. Hoffmann-La Roche Ag | Fc-receptor based affinity chromatography |
| HUE045466T2 (hu) | 2014-11-06 | 2019-12-30 | Hoffmann La Roche | Fc-régió-variánsok módosított FcRn-kötéssel és alkalmazási eljárások |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3040121B2 (ja) * | 1988-01-12 | 2000-05-08 | ジェネンテク，インコーポレイテッド | 増殖因子レセプターの機能を阻害することにより腫瘍細胞を処置する方法 |
| US5288612A (en) * | 1991-07-03 | 1994-02-22 | The Scripps Research Institute | Assay methods for detecting serum proteases, particularly activated protein C |
| EP0679189B1 (de) * | 1993-01-15 | 2003-06-04 | Genetics Institute, LLC | Klonierung von Enterokinase und Verfahren zu deren Verwendung |
| AR012035A1 (es) * | 1997-02-25 | 2000-09-27 | Corixa Corp | Metodo para detectar el cancer de prostata, metodo para monitorear el desarrollo del cancer de prostata, anticuerpo monoclonal que se une a un polipeptido, una cantidad terapeutica eficaz de anticuerpos monoclonales para preparar medicamentos y equipo para diagnostico |
| CA2281952C (en) * | 1997-02-25 | 2011-07-19 | Corixa Corporation | Compounds for immunotherapy of prostate cancer and methods for their use |
| US6800746B2 (en) * | 1997-02-25 | 2004-10-05 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US6657056B2 (en) * | 1997-02-25 | 2003-12-02 | Corixa Corporation | Compounds for immunotherapy of prostate cancer and methods for their use |
| US6043033A (en) * | 1997-02-27 | 2000-03-28 | Incyte Pharmaceuticals, Inc. | Human prostate-associated protease |
| US20030103981A1 (en) * | 1997-02-27 | 2003-06-05 | Incyte Genomics, Inc. | Methods of use of a prostate-associated protease in the diagnosis and treatment of prostate cancer |
| US20020119531A1 (en) * | 1997-02-27 | 2002-08-29 | Olga Bandman | Prostate-associated protease antibody |
| US6500938B1 (en) * | 1998-01-30 | 2002-12-31 | Incyte Genomics, Inc. | Composition for the detection of signaling pathway gene expression |
| AU4839999A (en) * | 1998-06-29 | 2000-01-17 | Myriad Genetics, Inc. | Tmprss2 is a tumor suppressor |
| US6291663B1 (en) * | 1999-03-03 | 2001-09-18 | Board Of Trustees Of The University Of Arkansas | TADG-12: a novel transmembrane serine protease overexpressed in a ovarian carcinoma |
| US6331427B1 (en) * | 1999-03-26 | 2001-12-18 | Millennium Pharmaceuticals, Inc. | Protease homologs |
| US20020192763A1 (en) * | 2000-04-17 | 2002-12-19 | Jiangchun Xu | Compositions and methods for the therapy and diagnosis of prostate cancer |
| US20020160382A1 (en) * | 2000-10-11 | 2002-10-31 | Lasek Amy W. | Genes expressed in colon cancer |
| US20030065157A1 (en) * | 2001-04-04 | 2003-04-03 | Lasek Amy W. | Genes expressed in lung cancer |
-
1999
- 1999-06-01 DK DK99927164.6T patent/DK1082341T3/da active
- 1999-06-01 CA CA2329137A patent/CA2329137C/en not_active Expired - Fee Related
- 1999-06-01 JP JP2000552152A patent/JP2002517185A/ja not_active Withdrawn
- 1999-06-01 AU AU44136/99A patent/AU773187B2/en not_active Ceased
- 1999-06-01 WO PCT/US1999/012253 patent/WO1999062942A2/en not_active Ceased
- 1999-06-01 AT AT99927164T patent/ATE490977T1/de active
- 1999-06-01 DE DE69943020T patent/DE69943020D1/de not_active Expired - Lifetime
- 1999-06-01 PT PT99927164T patent/PT1082341E/pt unknown
- 1999-06-01 EP EP99927164A patent/EP1082341B1/de not_active Expired - Lifetime
- 1999-06-01 IL IL13998899A patent/IL139988A0/xx not_active IP Right Cessation
-
2004
- 2004-05-25 AU AU2004202306A patent/AU2004202306C1/en not_active Ceased
-
2005
- 2005-08-09 US US11/200,973 patent/US20060275304A1/en not_active Abandoned
-
2008
- 2008-12-25 JP JP2008330218A patent/JP2009148265A/ja active Pending
-
2011
- 2011-03-08 CY CY20111100264T patent/CY1111906T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DK1082341T3 (da) | 2011-03-28 |
| EP1082341B1 (de) | 2010-12-08 |
| AU2004202306B2 (en) | 2007-05-24 |
| CA2329137A1 (en) | 1999-12-09 |
| AU773187B2 (en) | 2004-05-20 |
| PT1082341E (pt) | 2011-02-15 |
| CA2329137C (en) | 2011-09-20 |
| JP2002517185A (ja) | 2002-06-18 |
| EP1082341A2 (de) | 2001-03-14 |
| CY1111906T1 (el) | 2015-11-04 |
| WO1999062942A3 (en) | 2000-06-02 |
| WO1999062942A2 (en) | 1999-12-09 |
| JP2009148265A (ja) | 2009-07-09 |
| DE69943020D1 (de) | 2011-01-20 |
| AU2004202306A1 (en) | 2004-06-24 |
| IL139988A0 (en) | 2002-02-10 |
| AU2004202306C1 (en) | 2008-05-01 |
| AU4413699A (en) | 1999-12-20 |
| US20060275304A1 (en) | 2006-12-07 |
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Legal Events
| Date | Code | Title | Description |
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| UEP | Publication of translation of european patent specification |
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