JP2002516292A5 - - Google Patents
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- Publication number
- JP2002516292A5 JP2002516292A5 JP2000550512A JP2000550512A JP2002516292A5 JP 2002516292 A5 JP2002516292 A5 JP 2002516292A5 JP 2000550512 A JP2000550512 A JP 2000550512A JP 2000550512 A JP2000550512 A JP 2000550512A JP 2002516292 A5 JP2002516292 A5 JP 2002516292A5
- Authority
- JP
- Japan
- Prior art keywords
- immunogenic composition
- serogroup
- carrier
- composition according
- outer membrane
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 description 13
- 230000002163 immunogen Effects 0.000 description 10
- 101710116435 Outer membrane protein Proteins 0.000 description 4
- 239000002671 adjuvant Substances 0.000 description 2
- 230000028993 immune response Effects 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 150000002632 lipids Chemical class 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 229920001542 oligosaccharide Polymers 0.000 description 1
- 150000002482 oligosaccharides Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 239000003725 proteoliposome Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8735198P | 1998-05-29 | 1998-05-29 | |
| US60/087,351 | 1998-05-29 | ||
| US10644698P | 1998-10-30 | 1998-10-30 | |
| US60/106,446 | 1998-10-30 | ||
| PCT/US1999/011977 WO1999061053A1 (en) | 1998-05-29 | 1999-05-28 | Combination meningitidis b/c vaccines |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009219818A Division JP2009292851A (ja) | 1998-05-29 | 2009-09-24 | 組合わせの髄膜炎菌b/cワクチン |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2002516292A JP2002516292A (ja) | 2002-06-04 |
| JP2002516292A5 true JP2002516292A5 (enExample) | 2006-07-13 |
| JP5074644B2 JP5074644B2 (ja) | 2012-11-14 |
Family
ID=26776879
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000550512A Expired - Fee Related JP5074644B2 (ja) | 1998-05-29 | 1999-05-28 | 組合わせの髄膜炎菌b/cワクチン |
| JP2009219818A Pending JP2009292851A (ja) | 1998-05-29 | 2009-09-24 | 組合わせの髄膜炎菌b/cワクチン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009219818A Pending JP2009292851A (ja) | 1998-05-29 | 2009-09-24 | 組合わせの髄膜炎菌b/cワクチン |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US8007815B1 (enExample) |
| EP (2) | EP1079857B1 (enExample) |
| JP (2) | JP5074644B2 (enExample) |
| AT (1) | ATE346609T1 (enExample) |
| AU (2) | AU761495B2 (enExample) |
| BR (1) | BR9910749A (enExample) |
| CA (1) | CA2332963C (enExample) |
| CY (1) | CY1107550T1 (enExample) |
| DE (1) | DE69934225T2 (enExample) |
| DK (1) | DK1079857T3 (enExample) |
| ES (2) | ES2278446T3 (enExample) |
| NZ (1) | NZ508771A (enExample) |
| PT (2) | PT1079857E (enExample) |
| WO (1) | WO1999061053A1 (enExample) |
Families Citing this family (30)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2298900A1 (en) | 1996-09-17 | 2011-03-23 | Novartis Vaccines and Diagnostics, Inc. | Compositions and methods for treating intracellular diseases |
| ES2278446T3 (es) | 1998-05-29 | 2007-08-01 | Novartis Vaccines And Diagnostics, Inc. | Vacunas combinadas b/c contra la meningitis. |
| EP1179072A2 (en) | 1999-05-19 | 2002-02-13 | Chiron S.P.A. | Combination neisserial compositions |
| GB9928196D0 (en) | 1999-11-29 | 2000-01-26 | Chiron Spa | Combinations of B, C and other antigens |
| ES2588917T3 (es) * | 2000-01-17 | 2016-11-07 | Glaxosmithkline Biologicals Sa | Vacuna de VME suplementada contra meningococo |
| MXPA03000822A (es) | 2000-07-27 | 2004-11-01 | Childrens Hosp & Res Ct Oak | Vacunas para proteccion de espectro amplio contra enfermedades causadas por neisseria meningitidis. |
| GB0115176D0 (en) | 2001-06-20 | 2001-08-15 | Chiron Spa | Capular polysaccharide solubilisation and combination vaccines |
| ES2615362T3 (es) | 2001-07-27 | 2017-06-06 | Glaxosmithkline Biologicals Sa | Adhesinas de meningococos |
| MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| ES2397923T3 (es) | 2003-10-02 | 2013-03-12 | Novartis Ag | Vacunas líquidas para múltiples serogrupos meningocócicos |
| GB0419627D0 (en) | 2004-09-03 | 2004-10-06 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| GB0424092D0 (en) | 2004-10-29 | 2004-12-01 | Chiron Srl | Immunogenic bacterial vesicles with outer membrane proteins |
| CN101107007B (zh) | 2005-01-27 | 2011-08-17 | 奥克兰儿童医院及研究中心 | 对脑膜炎奈瑟球菌所致疾病具有广谱保护作用的gna1870囊泡疫苗 |
| AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
| HRP20120433T1 (en) * | 2007-10-19 | 2012-07-31 | Novartis@Ag | Meningococcal vaccine formulations |
| WO2011024072A2 (en) * | 2009-08-27 | 2011-03-03 | Novartis Ag | Hybrid polypeptides including meningococcal fhbp sequences |
| CA2808975C (en) | 2010-08-23 | 2018-10-30 | Wyeth Llc | Stable formulations of neisseria meningitidis rlp2086 antigens |
| CA2810971C (en) | 2010-09-10 | 2020-11-03 | Novartis Ag | Developments in meningococcal outer membrane vesicles |
| GB201015132D0 (en) * | 2010-09-10 | 2010-10-27 | Univ Bristol | Vaccine composition |
| KR101584871B1 (ko) | 2010-09-10 | 2016-01-22 | 와이어쓰 엘엘씨 | 네이세리아 메닝기티디스 orf2086 항원의 비-지질화된 변이체 |
| CA2865745C (en) | 2012-03-09 | 2018-01-09 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
| SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
| BR112015005056A2 (pt) * | 2012-09-06 | 2017-11-21 | Novartis Ag | vacinas de combinação com sorogrupo b meningococcus e d/t/p |
| AU2013320313B2 (en) | 2012-09-18 | 2018-07-12 | Glaxosmithkline Biologicals Sa | Outer membrane vesicles |
| CA2903716C (en) | 2013-03-08 | 2019-04-09 | Pfizer Inc. | Immunogenic fusion polypeptides |
| RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
| KR20190049940A (ko) | 2015-02-19 | 2019-05-09 | 화이자 인코포레이티드 | 나이세리아 메닌지티디스 조성물 및 그의 방법 |
| SG11201906519RA (en) | 2017-01-31 | 2019-08-27 | Pfizer | Neisseria meningitidis compositions and methods thereof |
| CA3155669A1 (en) | 2019-09-27 | 2021-04-01 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2848965A1 (de) | 1978-11-11 | 1980-05-22 | Behringwerke Ag | Verfahren zur herstellung von membranproteinen aus neisseria meningitidis und diese enthaltende vaccine |
| US4707543A (en) * | 1985-09-17 | 1987-11-17 | The United States Of America As Represented By The Secretary Of The Army | Process for the preparation of detoxified polysaccharide-outer membrane protein complexes, and their use as antibacterial vaccines |
| AU640118B2 (en) * | 1988-12-19 | 1993-08-19 | De Staat Der Nederlanden Vertegenwoordigd Door De Minister Van Welzijn, Volksgezonheid En Cultuur | Meningococcal class 1 outer-membrane protein vaccine |
| US7118757B1 (en) * | 1988-12-19 | 2006-10-10 | Wyeth Holdings Corporation | Meningococcal class 1 outer-membrane protein vaccine |
| WO1990014837A1 (en) | 1989-05-25 | 1990-12-13 | Chiron Corporation | Adjuvant formulation comprising a submicron oil droplet emulsion |
| DK0624376T3 (da) | 1993-05-13 | 2000-07-24 | American Cyanamid Co | Fremstilling og anvendelse af LOS-udtømte ydre membranproteiner af gram-negative cocci |
| DK0710118T3 (da) | 1994-04-20 | 1999-08-09 | Us Army | Vaccine mod infektioner med gram-negative bakterier |
| US6180111B1 (en) | 1995-05-18 | 2001-01-30 | University Of Maryland | Vaccine delivery system |
| PT854729E (pt) * | 1995-09-18 | 2004-08-31 | Us Army Med Res Mat Com Usamrm | Metodos melhorados para a producao de vacinas de subunidade multivalentes de proteossomas complexados nao covalentemente |
| DE19601754A1 (de) * | 1996-01-19 | 1997-07-24 | Hoechst Ag | Dictyocaulus viviparus Antigen zur Diagnose des Lungenwurmbefalls und zur Vakzinierung |
| US5846735A (en) * | 1996-04-18 | 1998-12-08 | University Of Iowa Research Foundation | Hepatitis C virus Fc-binding function |
| DE69708318T3 (de) * | 1996-08-27 | 2006-11-16 | Novartis Vaccines and Diagnostics, Inc., Emeryville | Neisseria meningitidis serogruppe b glykokonjugate und verfahren zu deren verwendung |
| US6558677B2 (en) * | 1996-10-15 | 2003-05-06 | Wendell D. Zollinger | Vaccine against gram negative bacteria |
| EP0994723A1 (en) * | 1997-06-24 | 2000-04-26 | Chiron Corporation | Methods of immunizing adults using anti-meningococcal vaccine compositions |
| JP2001510169A (ja) * | 1997-07-17 | 2001-07-31 | ノース アメリカン ワクチン, インコーポレイテッド | B型髄膜炎菌性ポーリンおよびH.influenzae多糖体を含む免疫原性結合体 |
| GB9727262D0 (en) | 1997-12-24 | 1998-02-25 | Smithkline Beecham Biolog | Vaccine |
| ES2278446T3 (es) | 1998-05-29 | 2007-08-01 | Novartis Vaccines And Diagnostics, Inc. | Vacunas combinadas b/c contra la meningitis. |
| WO2001034642A2 (en) | 1999-11-12 | 2001-05-17 | University Of Iowa Research Foundation | Control of neisserial membrane synthesis |
| MXPA03000822A (es) | 2000-07-27 | 2004-11-01 | Childrens Hosp & Res Ct Oak | Vacunas para proteccion de espectro amplio contra enfermedades causadas por neisseria meningitidis. |
| GB0220194D0 (en) | 2002-08-30 | 2002-10-09 | Chiron Spa | Improved vesicles |
| DK1587537T3 (da) | 2003-01-30 | 2012-07-16 | Novartis Ag | Injicerbare vacciner mod multiple meningococ-serogrupper |
| GB0316560D0 (en) | 2003-07-15 | 2003-08-20 | Chiron Srl | Vesicle filtration |
| ES2397923T3 (es) | 2003-10-02 | 2013-03-12 | Novartis Ag | Vacunas líquidas para múltiples serogrupos meningocócicos |
-
1999
- 1999-05-28 ES ES99926046T patent/ES2278446T3/es not_active Expired - Lifetime
- 1999-05-28 AU AU42215/99A patent/AU761495B2/en not_active Revoked
- 1999-05-28 US US09/701,453 patent/US8007815B1/en not_active Expired - Fee Related
- 1999-05-28 ES ES06076647.4T patent/ES2485940T3/es not_active Expired - Lifetime
- 1999-05-28 DE DE69934225T patent/DE69934225T2/de not_active Expired - Lifetime
- 1999-05-28 EP EP99926046A patent/EP1079857B1/en not_active Expired - Lifetime
- 1999-05-28 AT AT99926046T patent/ATE346609T1/de active
- 1999-05-28 BR BR9910749-0A patent/BR9910749A/pt not_active Application Discontinuation
- 1999-05-28 JP JP2000550512A patent/JP5074644B2/ja not_active Expired - Fee Related
- 1999-05-28 PT PT99926046T patent/PT1079857E/pt unknown
- 1999-05-28 DK DK99926046T patent/DK1079857T3/da active
- 1999-05-28 PT PT60766474T patent/PT1741443E/pt unknown
- 1999-05-28 CA CA2332963A patent/CA2332963C/en not_active Expired - Fee Related
- 1999-05-28 WO PCT/US1999/011977 patent/WO1999061053A1/en not_active Ceased
- 1999-05-28 EP EP20140169154 patent/EP2796148A3/en not_active Withdrawn
- 1999-05-28 NZ NZ508771A patent/NZ508771A/en not_active IP Right Cessation
-
2003
- 2003-09-02 AU AU2003244518A patent/AU2003244518A1/en not_active Withdrawn
-
2007
- 2007-01-31 CY CY20071100128T patent/CY1107550T1/el unknown
-
2009
- 2009-09-24 JP JP2009219818A patent/JP2009292851A/ja active Pending
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