|
US5939262A
(en)
*
|
1996-07-03 |
1999-08-17 |
Ambion, Inc. |
Ribonuclease resistant RNA preparation and utilization
|
|
DE19737442C2
(de)
*
|
1997-08-22 |
1999-06-24 |
Olfert Landt Tib Molbiol Synth |
Proteinumhüllte Polyribonukleinsäuren, ein Verfahren zu ihrer Herstellung und ihre Verwendung
|
|
AU9319398A
(en)
*
|
1997-09-19 |
1999-04-05 |
Sequitur, Inc. |
Sense mrna therapy
|
|
EP1892299A3
(en)
*
|
1997-09-19 |
2011-07-20 |
Life Technologies Corporation |
Sense mRNA therapy
|
|
WO2002018645A2
(en)
*
|
2000-08-28 |
2002-03-07 |
Oncomedx, Inc. |
5t4 rna in plasma and serum as a marker for neoplastic disease
|
|
US7767422B2
(en)
*
|
1998-09-22 |
2010-08-03 |
Oncomedx, Inc. |
Detection of 5T4 RNA in plasma and serum
|
|
US6777210B1
(en)
*
|
1998-09-24 |
2004-08-17 |
Ambion, Inc. |
Method and reagents for inactivating ribonucleases RNase A, RNase I and RNase T1
|
|
DE19956568A1
(de)
*
|
1999-01-30 |
2000-08-17 |
Roland Kreutzer |
Verfahren und Medikament zur Hemmung der Expression eines vorgegebenen Gens
|
|
KR20000065690A
(ko)
*
|
1999-04-08 |
2000-11-15 |
박종구 |
반응 특이성 및 안정성을 개선시킨 안티센스 올리고 뉴클레오타이드, 안티센스 ｄｎａ 및 그 제조방법
|
|
US7829693B2
(en)
*
|
1999-11-24 |
2010-11-09 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
|
DK1268766T3
(da)
*
|
2000-03-31 |
2006-04-10 |
Cambridge Antibody Tech |
Forbedringer af ribosom-display
|
|
GB0021303D0
(en)
*
|
2000-08-30 |
2000-10-18 |
Medinnova Sf |
Use
|
|
RU2189396C2
(ru)
*
|
2000-10-27 |
2002-09-20 |
Федеральное государственное учреждение науки и здравоохранения Нижегородский научно-исследовательский институт эпидемиологии и микробиологии им. акад. И.Н.Блохиной |
Способ обнаружения и дифференциации рнк энтеровирусов
|
|
US8546143B2
(en)
|
2001-01-09 |
2013-10-01 |
Alnylam Pharmaceuticals, Inc. |
Compositions and methods for inhibiting expression of a target gene
|
|
US20020172972A1
(en)
*
|
2001-05-15 |
2002-11-21 |
President And Fellows Of Harvard College |
Use of a selectively inactivatable enzyme to digest contaminating nucleic acid
|
|
JP2005514012A
(ja)
*
|
2001-12-06 |
2005-05-19 |
ザ アーロン ダイアモンド エイズ リサーチ センター |
キメラバクテリオファージ標準を使用する高感度ゲノムアッセイ
|
|
DE60330842D1
(de)
|
2002-01-28 |
2010-02-25 |
Ambion Inc |
Für den nachweis von nukleinsäuren kompetente biologische rohderivate
|
|
WO2003064625A2
(en)
|
2002-02-01 |
2003-08-07 |
Sequitur, Inc. |
Oligonucleotide compositions with enhanced efficiency
|
|
US20060009409A1
(en)
|
2002-02-01 |
2006-01-12 |
Woolf Tod M |
Double-stranded oligonucleotides
|
|
EP1545625B1
(en)
*
|
2002-06-07 |
2011-08-24 |
Kentucky Bioprocessing, LLC |
Flexible vaccine assembly and vaccine delivery platform
|
|
US7482116B2
(en)
|
2002-06-07 |
2009-01-27 |
Dna Genotek Inc. |
Compositions and methods for obtaining nucleic acids from sputum
|
|
WO2004085611A2
(en)
*
|
2003-03-21 |
2004-10-07 |
The Research Foundation Of State University Of New York |
Model for mutually exclusive domain folding molecular switch
|
|
GB2422196B
(en)
*
|
2003-05-20 |
2008-05-07 |
Investigen Inc |
System for detecting polynucleotides
|
|
JP2007524397A
(ja)
|
2003-07-03 |
2007-08-30 |
ザ・トラスティーズ・オブ・ザ・ユニバーシティ・オブ・ペンシルベニア |
Ｓｙｋキナーゼ発現の阻害
|
|
WO2005058933A1
(en)
*
|
2003-12-16 |
2005-06-30 |
Gentra Systems, Inc. |
Formulations and methods for denaturing proteins
|
|
JP2007531794A
(ja)
*
|
2004-04-05 |
2007-11-08 |
アルニラム ファーマスーティカルズ インコーポレイテッド |
オリゴヌクレオチドの合成および精製に使用する方法および反応試薬
|
|
EP1768998A2
(en)
*
|
2004-04-27 |
2007-04-04 |
Alnylam Pharmaceuticals Inc. |
Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety
|
|
EP3034510A1
(en)
*
|
2004-04-30 |
2016-06-22 |
Alnylam Pharmaceuticals Inc. |
Oligonucleotides comprising a c5-modified pyrimidine
|
|
EP1789553B1
(en)
*
|
2004-06-30 |
2014-03-26 |
Alnylam Pharmaceuticals Inc. |
Oligonucleotides comprising a non-phosphate backbone linkage
|
|
WO2006093526A2
(en)
|
2004-07-21 |
2006-09-08 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a modified or non-natural nucleobase
|
|
AU2005330637B2
(en)
|
2004-08-04 |
2012-09-20 |
Alnylam Pharmaceuticals, Inc. |
Oligonucleotides comprising a ligand tethered to a modified or non-natural nucleobase
|
|
US7309589B2
(en)
|
2004-08-20 |
2007-12-18 |
Vironix Llc |
Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing
|
|
EP1800126B1
(en)
*
|
2004-09-08 |
2014-12-17 |
The United States of America as represented by the Secretary of Health and Human Services, NIH |
Compositions and methods for the detection of hiv-1/hiv-2 infection
|
|
US8772254B2
(en)
*
|
2004-10-25 |
2014-07-08 |
Devgen N.V. |
Method and constructs for delivering double stranded RNA to pest organisms
|
|
WO2006052680A1
(en)
|
2004-11-05 |
2006-05-18 |
Qiagen North American Holdings, Inc. |
Compositions and methods for purifying nucleic acids from stabilization reagents
|
|
WO2007011902A2
(en)
*
|
2005-07-15 |
2007-01-25 |
Applera Corporation |
Methods for rna profiling
|
|
WO2007100711A2
(en)
*
|
2006-02-24 |
2007-09-07 |
Investigen, Inc. |
Methods and compositions for detecting polynucleotides
|
|
EP2066686A4
(en)
|
2006-10-06 |
2010-07-14 |
Dna Genotek Inc |
STABILIZING COMPOSITIONS AND METHODS FOR EXTRACTING A RIBONUCLEIC ACID
|
|
WO2008051817A1
(en)
*
|
2006-10-20 |
2008-05-02 |
Novartis Ag |
Compositions and method for monitoring bcr-abl expression
|
|
US20080096193A1
(en)
*
|
2006-10-24 |
2008-04-24 |
Charles Robert Bupp |
Methods and compositions for detecting polynucleotides
|
|
CN101173252B
(zh)
*
|
2006-10-31 |
2011-09-21 |
杭州市疾病预防控制中心 |
披甲rna及其制备方法
|
|
WO2008103702A2
(en)
*
|
2007-02-23 |
2008-08-28 |
Investigen, Inc. |
Methods and compositions for rapid light-activated isolation and detection of analytes
|
|
US7964350B1
(en)
|
2007-05-18 |
2011-06-21 |
Applied Biosystems, Llc |
Sample preparation for in situ nucleic acid analysis
|
|
US20110014723A1
(en)
*
|
2008-03-14 |
2011-01-20 |
Erdman Dean D |
Compositions and processes relating to human bocavirus
|
|
US8324149B2
(en)
*
|
2008-11-18 |
2012-12-04 |
The Board Of Trustees Of The Leland Stanford Junior University |
Encapsidation of heterologous entities into virus-like particles
|
|
US20100129902A1
(en)
|
2008-11-24 |
2010-05-27 |
Erhard Ralf Schoenbrunner |
Replication Stable and RNase Resistant Chimeras of Pestivirus with Insertion in 3' Nontranslated Region (3'NTR)
|
|
EP2955233A1
(en)
*
|
2008-12-19 |
2015-12-16 |
Life Technologies Corporation |
Proteinase K inhibitors, methods and compositions therefor
|
|
JP6121591B2
(ja)
*
|
2010-07-29 |
2017-04-26 |
エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ |
微生物核酸の定性的および定量的検出
|
|
EP2598654B2
(en)
|
2010-07-29 |
2023-08-02 |
F. Hoffmann-La Roche AG |
Generic sample preparation
|
|
US8877464B2
(en)
|
2010-07-29 |
2014-11-04 |
Roche Molecular Systems, Inc. |
Qualitative and quantitative detection of microbial nucleic acids
|
|
EP2598655B1
(en)
*
|
2010-07-29 |
2016-10-05 |
F.Hoffmann-La Roche Ag |
Qualitative and quantitative detection of microbial nucleic acids
|
|
CN107604097A
(zh)
|
2010-07-29 |
2018-01-19 |
霍夫曼-拉罗奇有限公司 |
用于多种参数的对照核酸
|
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
EP2426222A1
(en)
|
2010-09-07 |
2012-03-07 |
F. Hoffmann-La Roche AG |
Generic buffer for amplification
|
|
DK4108671T3
(da)
|
2010-10-01 |
2025-01-06 |
Modernatx Inc |
Modificerede nukleosider, nukleotider og nukleinsyrer samt anvendelser deraf
|
|
EP2465945A1
(en)
|
2010-12-17 |
2012-06-20 |
F. Hoffmann-La Roche AG |
Generic matrix for control nucleic acids
|
|
JP2014511687A
(ja)
|
2011-03-31 |
2014-05-19 |
モデルナ セラピューティクス インコーポレイテッド |
工学操作された核酸の送達および製剤
|
|
AU2012273121B2
(en)
|
2011-06-19 |
2016-08-25 |
Abogen, Inc. |
Devices, solutions and methods for sample collection
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
JP6113737B2
(ja)
|
2011-10-03 |
2017-04-12 |
モデルナティエックス インコーポレイテッドＭｏｄｅｒｎａＴＸ，Ｉｎｃ． |
修飾型のヌクレオシド、ヌクレオチドおよび核酸、ならびにそれらの使用方法
|
|
KR20140102759A
(ko)
|
2011-12-16 |
2014-08-22 |
모더나 세라퓨틱스, 인코포레이티드 |
변형된 뉴클레오사이드, 뉴클레오타이드 및 핵산 조성물
|
|
CN104160019A
(zh)
|
2012-03-13 |
2014-11-19 |
Emd密理博公司 |
使用离心辅助的感染以增加病毒滴度
|
|
EP2834259A4
(en)
|
2012-04-02 |
2016-08-24 |
Moderna Therapeutics Inc |
MODIFIED POLYNUCLEOTIDES
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US9597380B2
(en)
|
2012-11-26 |
2017-03-21 |
Modernatx, Inc. |
Terminally modified RNA
|
|
US9481903B2
(en)
|
2013-03-13 |
2016-11-01 |
Roche Molecular Systems, Inc. |
Systems and methods for detection of cells using engineered transduction particles
|
|
CA2905341C
(en)
|
2013-03-13 |
2021-08-24 |
GeneWeave Biosciences, Inc. |
Non-replicative transduction particles and transduction particle-based reporter systems
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
US10023626B2
(en)
|
2013-09-30 |
2018-07-17 |
Modernatx, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
EP3052521A1
(en)
|
2013-10-03 |
2016-08-10 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
|
US9540675B2
(en)
|
2013-10-29 |
2017-01-10 |
GeneWeave Biosciences, Inc. |
Reagent cartridge and methods for detection of cells
|
|
US20160355896A1
(en)
*
|
2014-02-10 |
2016-12-08 |
Amptec Gmbh |
Incoated rna
|
|
RU2021109685A
(ru)
|
2014-04-23 |
2021-04-13 |
МОДЕРНАТиЭкс, ИНК. |
Вакцины на основе нуклеиновых кислот
|
|
GB201412316D0
(en)
|
2014-07-10 |
2014-08-27 |
Momentum Bioscience Ltd |
Detecting the absence of micro-organisms
|
|
WO2016193070A1
(en)
|
2015-05-29 |
2016-12-08 |
Roche Diagnostics Gmbh |
A method of inactivating microbes by citraconic anhydride
|
|
US10351893B2
(en)
|
2015-10-05 |
2019-07-16 |
GeneWeave Biosciences, Inc. |
Reagent cartridge for detection of cells
|
|
EP3368694A1
(en)
|
2015-10-28 |
2018-09-05 |
Life Science Inkubator GmbH |
Use of vlp for the detection of nucleic acids
|
|
US10689689B2
(en)
*
|
2015-12-28 |
2020-06-23 |
Roche Molecular Systems, Inc. |
Generic method for the stabilization of specific RNA
|
|
US20170356025A1
(en)
|
2016-06-14 |
2017-12-14 |
Roche Molecular Systems, Inc. |
Internal control probes for improving pcr assay performance
|
|
EP3299471B1
(en)
|
2016-09-23 |
2019-10-23 |
Roche Diagniostics GmbH |
Methods for determining the amount of a nucleic acid of interest in an unprocessed sample
|
|
US10422012B2
(en)
|
2016-10-10 |
2019-09-24 |
Roche Molecular Systems, Inc. |
Devices comprising bacteriophage PHI6 internal control compositions
|
|
WO2019070854A1
(en)
|
2017-10-03 |
2019-04-11 |
Abbott Molecular Inc. |
ASSAY FOR DETECTION OF HEPATITIS C VIRUS (HCV)
|
|
ES2944360T3
(es)
|
2017-10-03 |
2023-06-20 |
Abbott Molecular Inc |
Ensayo para la detección del virus de la inmunodeficiencia humana (VIH)
|
|
ES2941076T3
(es)
|
2018-01-09 |
2023-05-16 |
Abbott Molecular Inc |
Ensayo para detectar Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis y Mycoplasma genitalium
|
|
JPWO2022045009A1
(enExample)
*
|
2020-08-24 |
2022-03-03 |
|
|
|
CN115896243A
(zh)
*
|
2022-11-25 |
2023-04-04 |
上海厦维医学检验实验室有限公司 |
基于混合酶体系的超灵敏反转录方法及其应用
|