JP2002513409A5 - - Google Patents
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- Publication number
- JP2002513409A5 JP2002513409A5 JP1998538798A JP53879898A JP2002513409A5 JP 2002513409 A5 JP2002513409 A5 JP 2002513409A5 JP 1998538798 A JP1998538798 A JP 1998538798A JP 53879898 A JP53879898 A JP 53879898A JP 2002513409 A5 JP2002513409 A5 JP 2002513409A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US3979597P | 1997-03-04 | 1997-03-04 | |
| US60/039,795 | 1997-03-04 | ||
| PCT/US1998/004299 WO1998039329A1 (en) | 1997-03-04 | 1998-03-04 | Amidoaromatic ring sulfonamide hydroxamic acid compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002513409A JP2002513409A (ja) | 2002-05-08 |
| JP2002513409A5 true JP2002513409A5 (enExample) | 2005-11-10 |
Family
ID=21907383
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53879798A Abandoned JP2002513408A (ja) | 1997-03-04 | 1998-03-04 | チオールスルホンアミドヒドロキサム酸化合物 |
| JP53879898A Ceased JP2002513409A (ja) | 1997-03-04 | 1998-03-04 | アミド芳香環スルホンアミドヒドロキサム酸化合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP53879798A Abandoned JP2002513408A (ja) | 1997-03-04 | 1998-03-04 | チオールスルホンアミドヒドロキサム酸化合物 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6451791B1 (enExample) |
| EP (2) | EP0983267B1 (enExample) |
| JP (2) | JP2002513408A (enExample) |
| AT (2) | ATE287885T1 (enExample) |
| CA (2) | CA2285405A1 (enExample) |
| DE (2) | DE69827940T2 (enExample) |
| DK (2) | DK0983267T3 (enExample) |
| ES (2) | ES2236893T3 (enExample) |
| PT (1) | PT983267E (enExample) |
| WO (1) | WO1998039329A1 (enExample) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6747027B1 (en) | 1996-07-22 | 2004-06-08 | Pharmacia Corporation | Thiol sulfonamide metalloprotease inhibitors |
| US6277885B1 (en) | 1999-01-27 | 2001-08-21 | American Cyanamid Company | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6200996B1 (en) | 1999-01-27 | 2001-03-13 | American Cyanamid Company | Heteroaryl acetylenic sulfonamide and phosphinic acid amide hydroxamic acid tace inhibitors |
| US6313123B1 (en) | 1999-01-27 | 2001-11-06 | American Cyanamid Company | Acetylenic sulfonamide thiol tace inhibitors |
| US6326516B1 (en) | 1999-01-27 | 2001-12-04 | American Cyanamid Company | Acetylenic β-sulfonamido and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6340691B1 (en) | 1999-01-27 | 2002-01-22 | American Cyanamid Company | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase and tace inhibitors |
| US6225311B1 (en) | 1999-01-27 | 2001-05-01 | American Cyanamid Company | Acetylenic α-amino acid-based sulfonamide hydroxamic acid tace inhibitors |
| BR0007784A (pt) | 1999-01-27 | 2002-02-05 | American Cyanamid Co | Composto, método para inibir mudanças patológicas mediadas pela enzima que converte o tnf-alfa (tace) em um mamìfero, composição farmacêutica, e, processo para preparar um composto |
| US6946473B2 (en) | 1999-01-27 | 2005-09-20 | Wyeth Holdings Corporation | Preparation and use of acetylenic ortho-sulfonamido and phosphinic acid amido bicyclic heteroaryl hydroxamic acids as TACE inhibitors |
| US6762178B2 (en) | 1999-01-27 | 2004-07-13 | Wyeth Holdings Corporation | Acetylenic aryl sulfonamide and phosphinic acid amide hydroxamic acid TACE inhibitors |
| US6753337B2 (en) | 1999-01-27 | 2004-06-22 | Wyeth Holdings Corporation | Alkynyl containing hydroxamic acid compounds as matrix metalloproteinase/tace inhibitors |
| US6800646B1 (en) | 1999-02-08 | 2004-10-05 | Pharmacia Corporation | Sulfamato hydroxamic acid metalloprotease inhibitor |
| AU6049800A (en) * | 1999-07-16 | 2001-02-05 | G.D. Searle & Co. | Method of changing conformation of a matrix metalloproteinase |
| US6869951B1 (en) | 1999-07-16 | 2005-03-22 | Pharmacia Corporation | Method of changing conformation of a matrix metalloproteinase |
| EP1088815A1 (en) * | 1999-09-28 | 2001-04-04 | Applied Research Systems ARS Holding N.V. | Pharmaceutically active sulfonyl amino acid derivatives |
| US6696456B1 (en) | 1999-10-14 | 2004-02-24 | The Procter & Gamble Company | Beta disubstituted metalloprotease inhibitors |
| MXPA02003811A (es) * | 1999-10-14 | 2002-09-30 | Procter & Gamble | Inhibidores beta di-sustituidos de las metaloproteasas. |
| US6808902B1 (en) | 1999-11-12 | 2004-10-26 | Amgen Inc. | Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules |
| RU2245876C2 (ru) | 2000-03-21 | 2005-02-10 | Дзе Проктер Энд Гэмбл Компани | Производные сульфонамидов и фармацевтическая композиция на их основе |
| CA2401728A1 (en) | 2000-03-21 | 2001-09-27 | The Procter & Gamble Company | Difluorobutyric acid metalloprotease inhibitors |
| WO2002003994A1 (en) * | 2000-07-12 | 2002-01-17 | G.D. Searle & Co. | N sulfonyl aminoacid derivatives as inhibitors of metalloproteinase |
| TR201809678T4 (tr) | 2001-06-26 | 2018-07-23 | Amgen Fremont Inc | Opgl ye karşi antikorlar. |
| JP2005507937A (ja) | 2001-11-01 | 2005-03-24 | ワイス・ホールディングズ・コーポレイション | マトリックスメタロプロテイナーゼおよびｔａｃｅ阻害剤としてのアレンアリールスルホンアミドヒドロキサム酸 |
| CA2483314A1 (en) | 2002-04-25 | 2003-11-06 | Pharmacia Corporation | Piperidinyl-and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors |
| JP4002927B2 (ja) | 2002-05-29 | 2007-11-07 | メルク エンド カムパニー インコーポレーテッド | 炭疸病治療および致死因子阻害に有用な化合物 |
| US7199155B2 (en) | 2002-12-23 | 2007-04-03 | Wyeth Holdings Corporation | Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors |
| WO2004060346A2 (en) | 2002-12-30 | 2004-07-22 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
| CA2566191A1 (en) | 2004-05-11 | 2005-12-15 | Merck & Co., Inc. | Process for making n-sulfonated-amino acid derivatives |
| JP5324785B2 (ja) * | 2005-10-28 | 2013-10-23 | 武田薬品工業株式会社 | 複素環アミド化合物及びその用途 |
| US8232427B2 (en) * | 2006-03-29 | 2012-07-31 | Novartis Ag | Selective hydroxamate based MMP inhibitors |
| EP2149568A1 (en) | 2008-07-22 | 2010-02-03 | Bracco Imaging S.p.A | Aryl-sulphonamidic dimers as metalloproteases inhibitors |
| EP2147684A1 (en) * | 2008-07-22 | 2010-01-27 | Bracco Imaging S.p.A | Diagnostic Agents Selective Against Metalloproteases |
| US9023318B2 (en) | 2011-06-08 | 2015-05-05 | Siemens Medical Solutions Usa, Inc. | Compounds with matrix-metalloproteinase inhibitory activity and imaging agents thereof |
| WO2019102488A1 (en) | 2017-11-27 | 2019-05-31 | Council Of Scientific & Industrial Research | Indole (sulfomyl) n-hydroxy benzamide derivatives as selective hdac inhibitors |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4337197A (en) * | 1980-10-31 | 1982-06-29 | E. R. Squibb & Sons, Inc. | O-sulfated β-lactam hydroxamic acids and intermediates |
| US5552419A (en) | 1993-01-06 | 1996-09-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| US5506242A (en) * | 1993-01-06 | 1996-04-09 | Ciba-Geigy Corporation | Arylsufonamido-substituted hydroxamic acids |
| US5646167A (en) * | 1993-01-06 | 1997-07-08 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamix acids |
| US5455258A (en) | 1993-01-06 | 1995-10-03 | Ciba-Geigy Corporation | Arylsulfonamido-substituted hydroxamic acids |
| AU690703B2 (en) | 1994-06-22 | 1998-04-30 | British Biotech Pharmaceuticals Limited | Metalloproteinase inhibitors |
| GB9503749D0 (en) | 1995-02-24 | 1995-04-12 | British Biotech Pharm | Synthesis of hydroxamic acid derivatives |
| US5863949A (en) * | 1995-03-08 | 1999-01-26 | Pfizer Inc | Arylsulfonylamino hydroxamic acid derivatives |
| ES2185750T3 (es) * | 1995-08-08 | 2003-05-01 | Ono Pharmaceutical Co | Derivados de acido hidroxamico utiles para la inhibicion gelatinasa. |
| EA003294B1 (ru) * | 1995-12-08 | 2003-04-24 | Агурон Фармасьютикалс, Инк. | Ингибиторы металлопротеиназы, фармацевтические композиции, их содержащие, и их фармацевтические применения |
| CA2242416C (en) | 1996-01-23 | 2006-03-21 | Shionogi & Co., Ltd. | Sulfonated amino acid derivatives and metalloproteinase inhibitors containing the same |
| NZ325939A (en) | 1996-01-23 | 2000-06-23 | Shionogi & Co | Sulphonated amino acid derivatives and matrix metalloproteinase inhibitors (MMP) containing these derivatives |
| GB9715962D0 (en) | 1996-08-23 | 1997-10-01 | Zeneca Ltd | Sulfonamides |
-
1998
- 1998-03-04 EP EP98911480A patent/EP0983267B1/en not_active Expired - Lifetime
- 1998-03-04 DE DE69827940T patent/DE69827940T2/de not_active Expired - Fee Related
- 1998-03-04 DE DE69828783T patent/DE69828783T2/de not_active Expired - Fee Related
- 1998-03-04 PT PT98911480T patent/PT983267E/pt unknown
- 1998-03-04 AT AT98911480T patent/ATE287885T1/de not_active IP Right Cessation
- 1998-03-04 ES ES98911480T patent/ES2236893T3/es not_active Expired - Lifetime
- 1998-03-04 AT AT98911479T patent/ATE283848T1/de not_active IP Right Cessation
- 1998-03-04 DK DK98911480T patent/DK0983267T3/da active
- 1998-03-04 WO PCT/US1998/004299 patent/WO1998039329A1/en not_active Ceased
- 1998-03-04 JP JP53879798A patent/JP2002513408A/ja not_active Abandoned
- 1998-03-04 JP JP53879898A patent/JP2002513409A/ja not_active Ceased
- 1998-03-04 EP EP98911479A patent/EP0977745B1/en not_active Expired - Lifetime
- 1998-03-04 US US09/230,205 patent/US6451791B1/en not_active Expired - Fee Related
- 1998-03-04 CA CA002285405A patent/CA2285405A1/en not_active Abandoned
- 1998-03-04 CA CA002282399A patent/CA2282399A1/en not_active Abandoned
- 1998-03-04 ES ES98911479T patent/ES2234103T3/es not_active Expired - Lifetime
- 1998-03-04 DK DK98911479T patent/DK0977745T3/da active