JP2002512521A - ３２個のヒト分泌タンパク質 - Google Patents
３２個のヒト分泌タンパク質Info
- Publication number
- JP2002512521A JP2002512521A JP50089899A JP50089899A JP2002512521A JP 2002512521 A JP2002512521 A JP 2002512521A JP 50089899 A JP50089899 A JP 50089899A JP 50089899 A JP50089899 A JP 50089899A JP 2002512521 A JP2002512521 A JP 2002512521A
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- Prior art keywords
- sequence
- polypeptide
- cells
- seq
- gene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 102000003298 tumor necrosis factor receptor Human genes 0.000 description 1
- 208000035408 type 1 diabetes mellitus 1 Diseases 0.000 description 1
- 201000008297 typhoid fever Diseases 0.000 description 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
- 238000010798 ubiquitination Methods 0.000 description 1
- 230000034512 ubiquitination Effects 0.000 description 1
- 210000003606 umbilical vein Anatomy 0.000 description 1
- 241001430294 unidentified retrovirus Species 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 210000002229 urogenital system Anatomy 0.000 description 1
- 206010046766 uterine cancer Diseases 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
- 208000007089 vaccinia Diseases 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- 208000023577 vascular insufficiency disease Diseases 0.000 description 1
- 210000002845 virion Anatomy 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 239000011715 vitamin B12 Substances 0.000 description 1
- 229940011671 vitamin b6 Drugs 0.000 description 1
- 239000012224 working solution Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/525—Tumour necrosis factor [TNF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4809397P | 1997-05-30 | 1997-05-30 | |
| US4403997P | 1997-05-30 | 1997-05-30 | |
| US4835697P | 1997-05-30 | 1997-05-30 | |
| US4810197P | 1997-05-30 | 1997-05-30 | |
| US5093597P | 1997-05-30 | 1997-05-30 | |
| US4819097P | 1997-05-30 | 1997-05-30 | |
| US5629697P | 1997-08-29 | 1997-08-29 | |
| US5625097P | 1997-08-29 | 1997-08-29 | |
| US5629397P | 1997-08-29 | 1997-08-29 | |
| US60/056,250 | 1997-08-29 | ||
| US60/050,935 | 1997-08-29 | ||
| US60/048,101 | 1997-08-29 | ||
| US60/056,293 | 1997-08-29 | ||
| US60/048,093 | 1997-08-29 | ||
| US60/048,356 | 1997-08-29 | ||
| US60/048,190 | 1997-08-29 | ||
| US60/056,296 | 1997-08-29 | ||
| US60/044,039 | 1997-08-29 | ||
| PCT/US1998/010868 WO1998054206A1 (en) | 1997-05-30 | 1998-05-28 | 32 human secreted proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002512521A true JP2002512521A (ja) | 2002-04-23 |
| JP2002512521A5 JP2002512521A5 (https=) | 2005-12-08 |
Family
ID=27578175
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50089899A Pending JP2002512521A (ja) | 1997-05-30 | 1998-05-28 | ３２個のヒト分泌タンパク質 |
Country Status (11)
| Country | Link |
|---|---|
| US (4) | US6531447B1 (https=) |
| EP (2) | EP2332975A1 (https=) |
| JP (1) | JP2002512521A (https=) |
| AT (1) | ATE487737T1 (https=) |
| AU (1) | AU7801998A (https=) |
| CA (1) | CA2291221A1 (https=) |
| CY (1) | CY1111950T1 (https=) |
| DE (1) | DE69841994D1 (https=) |
| DK (1) | DK1015477T3 (https=) |
| PT (1) | PT1015477E (https=) |
| WO (1) | WO1998054206A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7129061B1 (en) * | 1996-08-07 | 2006-10-31 | Biogen Idec Ma Inc. | Tumor necrosis factor related ligand |
| EP0837128A3 (en) * | 1996-10-21 | 1999-04-28 | Smithkline Beecham Corporation | Human G-protein coupled receptor, HLYAZ61 |
| TW546381B (en) * | 1997-04-18 | 2003-08-11 | Chugai Pharmaceutical Co Ltd | Transcriptional regulator containing a bromo-domain |
| JP2002512521A (ja) | 1997-05-30 | 2002-04-23 | ヒューマン ジノーム サイエンシーズ，インコーポレイテッド | ３２個のヒト分泌タンパク質 |
| US7001992B2 (en) | 1997-05-30 | 2006-02-21 | Human Genome Sciences, Inc. | Antibodies to secreted protein HEMCM42 |
| WO2000011942A1 (en) * | 1998-09-01 | 2000-03-09 | Gene Logic, Inc. | IDENTIFICATION OF A cDNA ASSOCIATED WITH ISCHEMIA IN HUMAN HEART TISSUE |
| JP2002540763A (ja) * | 1999-02-10 | 2002-12-03 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ３３個のヒト分泌タンパク質 |
| US6372490B1 (en) * | 1999-02-23 | 2002-04-16 | Curagen Corporation | Nucleic acid encoding the MDM interacting protein |
| FR2797447B1 (fr) * | 1999-08-12 | 2004-04-02 | Univ Clermont Auvergne | "odorant-binding" proteines humaines fixant des ligands hydrophobes:polypeptides et polynucleotides codant lesdits polypeptides et leurs applications |
| AU1438201A (en) * | 1999-10-29 | 2001-05-14 | Human Genome Sciences, Inc. | 25 human secreted proteins |
| AU1437901A (en) * | 1999-10-29 | 2001-05-14 | Human Genome Sciences, Inc. | 26 human secreted proteins |
| US6727225B2 (en) | 1999-12-20 | 2004-04-27 | Immunex Corporation | TWEAK receptor |
| EP1239869B1 (en) | 1999-12-20 | 2013-08-28 | Immunex Corporation | Tweak receptor |
| EP1174502A1 (en) * | 2000-07-18 | 2002-01-23 | Schering Corporation | Type 2 dendritic cell precursor derived coding nucleic acids and related compositions and methods |
| CA2478925C (en) | 2002-04-26 | 2016-06-07 | Robert Lee Fahrner | Non-affinity purification of proteins |
| DE602004006871T2 (de) | 2003-07-24 | 2008-02-07 | Amgen Inc., Thousand Oaks | Zusammensetzungen und verfahren, die multimere und oligomere lösliche fragmente des tweak-rezeptors betreffen |
| EP2529619B1 (en) | 2005-02-17 | 2015-09-23 | Biogen MA Inc. | Treating neurological disorders |
| JP5339901B2 (ja) | 2005-05-10 | 2013-11-13 | バイオジェン・アイデック・エムエイ・インコーポレイテッド | 炎症傷害の処置および評価 |
| EP1876448A1 (en) * | 2005-09-30 | 2008-01-09 | DIGILAB BioVisioN GmbH | Method and analytical reagents for identifying therapeutics using biomarkers responsive to thiazolidinediones. |
| PL2565204T3 (pl) | 2007-07-27 | 2016-03-31 | Immatics Biotechnologies Gmbh | Nowe immunogenne epitopy do immunoterapii |
| WO2009020933A2 (en) | 2007-08-03 | 2009-02-12 | Facet Biotech Corporation | Therapeutic use of anti-tweak receptor antibodies |
| GB0809592D0 (en) * | 2008-05-27 | 2008-07-02 | Imp Innovations Ltd | Biomaterials |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US912292A (en) * | 1907-05-03 | 1909-02-16 | Morris E Curtis | Machine for making tubes. |
| US912293A (en) * | 1908-02-03 | 1909-02-16 | Nat Regulator Company | Temperature-regulating device. |
| US3773919A (en) | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4263428A (en) | 1978-03-24 | 1981-04-21 | The Regents Of The University Of California | Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same |
| EP0052322B1 (de) | 1980-11-10 | 1985-03-27 | Gersonde, Klaus, Prof. Dr. | Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens |
| IE52535B1 (en) | 1981-02-16 | 1987-12-09 | Ici Plc | Continuous release pharmaceutical compositions |
| US4485045A (en) | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| JPS58118008A (ja) | 1982-01-06 | 1983-07-13 | Nec Corp | デ−タ処理装置 |
| DE3374837D1 (en) | 1982-02-17 | 1988-01-21 | Ciba Geigy Ag | Lipids in the aqueous phase |
| EP0102324A3 (de) | 1982-07-29 | 1984-11-07 | Ciba-Geigy Ag | Lipide und Tenside in wässriger Phase |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| HUT35524A (en) | 1983-08-02 | 1985-07-29 | Hoechst Ag | Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance |
| DE3483949D1 (de) | 1983-09-26 | 1991-02-21 | Udo Dr Med Ehrenfeld | Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr. |
| EP0143949B1 (en) | 1983-11-01 | 1988-10-12 | TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION | Pharmaceutical composition containing urokinase |
| JPS6147500A (ja) | 1984-08-15 | 1986-03-07 | Res Dev Corp Of Japan | キメラモノクロ−ナル抗体及びその製造法 |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4631211A (en) | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
| EP0232262A4 (en) | 1985-08-15 | 1989-09-19 | Stauffer Chemical Co | TRYPTOPHANE GENERATING MICROORGANISM. |
| JPS63501765A (ja) | 1985-11-01 | 1988-07-21 | インタ−ナショナル、ジェネティック、エンジニアリング インコ−ポレ−テッド | 抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途 |
| US5128256A (en) | 1987-01-12 | 1992-07-07 | Stratagene | DNA cloning vectors with in vivo excisable plasmids |
| EP0394827A1 (en) | 1989-04-26 | 1990-10-31 | F. Hoffmann-La Roche Ag | Chimaeric CD4-immunoglobulin polypeptides |
| ES2120949T4 (es) | 1990-06-28 | 2011-12-29 | Sanofi-Aventis Deutschland Gmbh 50% | Proteinas de fusión con porciones de inmunoglobulinas, su preparación y empleo. |
| IL111125A0 (en) * | 1994-05-11 | 1994-12-29 | Yeda Res & Dev | Soluble oligomeric tnf/ngf super family ligand receptors and their use |
| WO1996034891A1 (en) | 1995-05-05 | 1996-11-07 | Human Genome Sciences, Inc. | Human chemokine beta-8, chemokine beta-1 and macrophage inflammatory protein-4 |
| FR2741075B1 (fr) * | 1995-11-15 | 1998-01-30 | Rech De Pathologie Appliquee S | Conjugues peptidiques, leur utilisation a titre de medicament et compositions les contenant |
| JP2001513626A (ja) | 1997-02-12 | 2001-09-04 | アボツト・ラボラトリーズ | 疾患の治療及び診断のために有用なｔｎｆファミリーのメンバー |
| JP2002512521A (ja) * | 1997-05-30 | 2002-04-23 | ヒューマン ジノーム サイエンシーズ，インコーポレイテッド | ３２個のヒト分泌タンパク質 |
| WO1998055508A2 (en) * | 1997-06-03 | 1998-12-10 | Sagami Chemical Research Center | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS |
| US6051385A (en) * | 1997-10-22 | 2000-04-18 | The Regents Of The University Of Michigan | Compositions and methods for identifying and testing therapeutics against HSV infection |
| WO1999061471A2 (en) | 1998-05-29 | 1999-12-02 | Incyte Pharmaceuticals, Inc. | Human transmembrane proteins |
| EP1239869B1 (en) * | 1999-12-20 | 2013-08-28 | Immunex Corporation | Tweak receptor |
-
1998
- 1998-05-28 JP JP50089899A patent/JP2002512521A/ja active Pending
- 1998-05-28 PT PT98926105T patent/PT1015477E/pt unknown
- 1998-05-28 DE DE69841994T patent/DE69841994D1/de not_active Expired - Lifetime
- 1998-05-28 AT AT98926105T patent/ATE487737T1/de active
- 1998-05-28 EP EP10180663A patent/EP2332975A1/en not_active Withdrawn
- 1998-05-28 CA CA002291221A patent/CA2291221A1/en not_active Abandoned
- 1998-05-28 WO PCT/US1998/010868 patent/WO1998054206A1/en not_active Ceased
- 1998-05-28 DK DK98926105.2T patent/DK1015477T3/da active
- 1998-05-28 AU AU78019/98A patent/AU7801998A/en not_active Abandoned
- 1998-05-28 EP EP98926105A patent/EP1015477B1/en not_active Expired - Lifetime
-
2000
- 2000-10-18 US US09/690,454 patent/US6531447B1/en not_active Expired - Lifetime
-
2002
- 2002-02-05 US US10/062,599 patent/US20030195346A1/en not_active Abandoned
-
2006
- 2006-03-02 US US11/366,001 patent/US20060147982A1/en not_active Abandoned
-
2007
- 2007-06-25 US US11/767,824 patent/US20070248593A1/en not_active Abandoned
-
2011
- 2011-01-27 CY CY20111100083T patent/CY1111950T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1015477A1 (en) | 2000-07-05 |
| US20030195346A1 (en) | 2003-10-16 |
| DK1015477T3 (da) | 2011-02-07 |
| CY1111950T1 (el) | 2015-11-04 |
| EP2332975A1 (en) | 2011-06-15 |
| CA2291221A1 (en) | 1998-12-03 |
| WO1998054206A1 (en) | 1998-12-03 |
| US20060147982A1 (en) | 2006-07-06 |
| EP1015477B1 (en) | 2010-11-10 |
| EP1015477A4 (en) | 2004-05-26 |
| AU7801998A (en) | 1998-12-30 |
| PT1015477E (pt) | 2010-12-28 |
| DE69841994D1 (de) | 2010-12-23 |
| US20070248593A1 (en) | 2007-10-25 |
| ATE487737T1 (de) | 2010-11-15 |
| US6531447B1 (en) | 2003-03-11 |
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