CA2291221A1 - 32 human secreted proteins - Google Patents

32 human secreted proteins Download PDF

Info

Publication number
CA2291221A1
CA2291221A1 CA002291221A CA2291221A CA2291221A1 CA 2291221 A1 CA2291221 A1 CA 2291221A1 CA 002291221 A CA002291221 A CA 002291221A CA 2291221 A CA2291221 A CA 2291221A CA 2291221 A1 CA2291221 A1 CA 2291221A1
Authority
CA
Canada
Prior art keywords
polypeptide
seq
sequence
cells
gene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002291221A
Other languages
English (en)
French (fr)
Inventor
Steven M. Ruben
Craig A. Rosen
Kenneth C. Carter
Patrick J. Dillon
Gregory A. Endress
Guo-Liang Yu
Jian Ni
Ping Feng
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Human Genome Sciences Inc
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2291221A1 publication Critical patent/CA2291221A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
CA002291221A 1997-05-30 1998-05-28 32 human secreted proteins Abandoned CA2291221A1 (en)

Applications Claiming Priority (19)

Application Number Priority Date Filing Date Title
US4809397P 1997-05-30 1997-05-30
US4403997P 1997-05-30 1997-05-30
US4835697P 1997-05-30 1997-05-30
US4810197P 1997-05-30 1997-05-30
US5093597P 1997-05-30 1997-05-30
US4819097P 1997-05-30 1997-05-30
US5629697P 1997-08-29 1997-08-29
US5625097P 1997-08-29 1997-08-29
US5629397P 1997-08-29 1997-08-29
US60/056,250 1997-08-29
US60/050,935 1997-08-29
US60/048,101 1997-08-29
US60/056,293 1997-08-29
US60/048,093 1997-08-29
US60/048,356 1997-08-29
US60/048,190 1997-08-29
US60/056,296 1997-08-29
US60/044,039 1997-08-29
PCT/US1998/010868 WO1998054206A1 (en) 1997-05-30 1998-05-28 32 human secreted proteins

Publications (1)

Publication Number Publication Date
CA2291221A1 true CA2291221A1 (en) 1998-12-03

Family

ID=27578175

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002291221A Abandoned CA2291221A1 (en) 1997-05-30 1998-05-28 32 human secreted proteins

Country Status (11)

Country Link
US (4) US6531447B1 (https=)
EP (2) EP2332975A1 (https=)
JP (1) JP2002512521A (https=)
AT (1) ATE487737T1 (https=)
AU (1) AU7801998A (https=)
CA (1) CA2291221A1 (https=)
CY (1) CY1111950T1 (https=)
DE (1) DE69841994D1 (https=)
DK (1) DK1015477T3 (https=)
PT (1) PT1015477E (https=)
WO (1) WO1998054206A1 (https=)

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EP0837128A3 (en) * 1996-10-21 1999-04-28 Smithkline Beecham Corporation Human G-protein coupled receptor, HLYAZ61
TW546381B (en) * 1997-04-18 2003-08-11 Chugai Pharmaceutical Co Ltd Transcriptional regulator containing a bromo-domain
JP2002512521A (ja) 1997-05-30 2002-04-23 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド ３２個のヒト分泌タンパク質
US7001992B2 (en) 1997-05-30 2006-02-21 Human Genome Sciences, Inc. Antibodies to secreted protein HEMCM42
WO2000011942A1 (en) * 1998-09-01 2000-03-09 Gene Logic, Inc. IDENTIFICATION OF A cDNA ASSOCIATED WITH ISCHEMIA IN HUMAN HEART TISSUE
JP2002540763A (ja) * 1999-02-10 2002-12-03 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ３３個のヒト分泌タンパク質
US6372490B1 (en) * 1999-02-23 2002-04-16 Curagen Corporation Nucleic acid encoding the MDM interacting protein
FR2797447B1 (fr) * 1999-08-12 2004-04-02 Univ Clermont Auvergne "odorant-binding" proteines humaines fixant des ligands hydrophobes:polypeptides et polynucleotides codant lesdits polypeptides et leurs applications
AU1438201A (en) * 1999-10-29 2001-05-14 Human Genome Sciences, Inc. 25 human secreted proteins
AU1437901A (en) * 1999-10-29 2001-05-14 Human Genome Sciences, Inc. 26 human secreted proteins
US6727225B2 (en) 1999-12-20 2004-04-27 Immunex Corporation TWEAK receptor
EP1239869B1 (en) 1999-12-20 2013-08-28 Immunex Corporation Tweak receptor
EP1174502A1 (en) * 2000-07-18 2002-01-23 Schering Corporation Type 2 dendritic cell precursor derived coding nucleic acids and related compositions and methods
CA2478925C (en) 2002-04-26 2016-06-07 Robert Lee Fahrner Non-affinity purification of proteins
DE602004006871T2 (de) 2003-07-24 2008-02-07 Amgen Inc., Thousand Oaks Zusammensetzungen und verfahren, die multimere und oligomere lösliche fragmente des tweak-rezeptors betreffen
EP2529619B1 (en) 2005-02-17 2015-09-23 Biogen MA Inc. Treating neurological disorders
JP5339901B2 (ja) 2005-05-10 2013-11-13 バイオジェン・アイデック・エムエイ・インコーポレイテッド 炎症傷害の処置および評価
EP1876448A1 (en) * 2005-09-30 2008-01-09 DIGILAB BioVisioN GmbH Method and analytical reagents for identifying therapeutics using biomarkers responsive to thiazolidinediones.
PL2565204T3 (pl) 2007-07-27 2016-03-31 Immatics Biotechnologies Gmbh Nowe immunogenne epitopy do immunoterapii
WO2009020933A2 (en) 2007-08-03 2009-02-12 Facet Biotech Corporation Therapeutic use of anti-tweak receptor antibodies
GB0809592D0 (en) * 2008-05-27 2008-07-02 Imp Innovations Ltd Biomaterials

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US912293A (en) * 1908-02-03 1909-02-16 Nat Regulator Company Temperature-regulating device.
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
US4263428A (en) 1978-03-24 1981-04-21 The Regents Of The University Of California Bis-anthracycline nucleic acid function inhibitors and improved method for administering the same
EP0052322B1 (de) 1980-11-10 1985-03-27 Gersonde, Klaus, Prof. Dr. Verfahren zur Herstellung von Lipid-Vesikeln durch Ultraschallbehandlung, Anwendung des Verfahrens und Vorrichtung zur Durchführung des Verfahrens
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4485045A (en) 1981-07-06 1984-11-27 Research Corporation Synthetic phosphatidyl cholines useful in forming liposomes
JPS58118008A (ja) 1982-01-06 1983-07-13 Nec Corp デ−タ処理装置
DE3374837D1 (en) 1982-02-17 1988-01-21 Ciba Geigy Ag Lipids in the aqueous phase
EP0102324A3 (de) 1982-07-29 1984-11-07 Ciba-Geigy Ag Lipide und Tenside in wässriger Phase
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4544545A (en) 1983-06-20 1985-10-01 Trustees University Of Massachusetts Liposomes containing modified cholesterol for organ targeting
HUT35524A (en) 1983-08-02 1985-07-29 Hoechst Ag Process for preparing pharmaceutical compositions containing regulatory /regulative/ peptides providing for the retarded release of the active substance
DE3483949D1 (de) 1983-09-26 1991-02-21 Udo Dr Med Ehrenfeld Mittel und erzeugnis fuer die diagnose und therapie von tumoren sowie zur behandlung von schwaechen der zelligen und humoralen immunabwehr.
EP0143949B1 (en) 1983-11-01 1988-10-12 TERUMO KABUSHIKI KAISHA trading as TERUMO CORPORATION Pharmaceutical composition containing urokinase
JPS6147500A (ja) 1984-08-15 1986-03-07 Res Dev Corp Of Japan キメラモノクロ−ナル抗体及びその製造法
EP0173494A3 (en) 1984-08-27 1987-11-25 The Board Of Trustees Of The Leland Stanford Junior University Chimeric receptors by dna splicing and expression
GB8422238D0 (en) 1984-09-03 1984-10-10 Neuberger M S Chimeric proteins
US4631211A (en) 1985-03-25 1986-12-23 Scripps Clinic & Research Foundation Means for sequential solid phase organic synthesis and methods using the same
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JPS63501765A (ja) 1985-11-01 1988-07-21 インタ−ナショナル、ジェネティック、エンジニアリング　インコ−ポレ−テッド 抗体遺伝子のモジュ−ル組立体、それにより産生された抗体及び用途
US5128256A (en) 1987-01-12 1992-07-07 Stratagene DNA cloning vectors with in vivo excisable plasmids
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IL111125A0 (en) * 1994-05-11 1994-12-29 Yeda Res & Dev Soluble oligomeric tnf/ngf super family ligand receptors and their use
WO1996034891A1 (en) 1995-05-05 1996-11-07 Human Genome Sciences, Inc. Human chemokine beta-8, chemokine beta-1 and macrophage inflammatory protein-4
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JP2001513626A (ja) 1997-02-12 2001-09-04 アボツト・ラボラトリーズ 疾患の治療及び診断のために有用なｔｎｆファミリーのメンバー
JP2002512521A (ja) * 1997-05-30 2002-04-23 ヒューマン ジノーム サイエンシーズ，インコーポレイテッド ３２個のヒト分泌タンパク質
WO1998055508A2 (en) * 1997-06-03 1998-12-10 Sagami Chemical Research Center HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND DNAs ENCODING THESE PROTEINS
US6051385A (en) * 1997-10-22 2000-04-18 The Regents Of The University Of Michigan Compositions and methods for identifying and testing therapeutics against HSV infection
WO1999061471A2 (en) 1998-05-29 1999-12-02 Incyte Pharmaceuticals, Inc. Human transmembrane proteins
EP1239869B1 (en) * 1999-12-20 2013-08-28 Immunex Corporation Tweak receptor

Also Published As

Publication number Publication date
EP1015477A1 (en) 2000-07-05
US20030195346A1 (en) 2003-10-16
DK1015477T3 (da) 2011-02-07
CY1111950T1 (el) 2015-11-04
EP2332975A1 (en) 2011-06-15
WO1998054206A1 (en) 1998-12-03
US20060147982A1 (en) 2006-07-06
JP2002512521A (ja) 2002-04-23
EP1015477B1 (en) 2010-11-10
EP1015477A4 (en) 2004-05-26
AU7801998A (en) 1998-12-30
PT1015477E (pt) 2010-12-28
DE69841994D1 (de) 2010-12-23
US20070248593A1 (en) 2007-10-25
ATE487737T1 (de) 2010-11-15
US6531447B1 (en) 2003-03-11

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20150528