|
US6727230B1
(en)
|
1994-03-25 |
2004-04-27 |
Coley Pharmaceutical Group, Inc. |
Immune stimulation by phosphorothioate oligonucleotide analogs
|
|
US6429199B1
(en)
*
|
1994-07-15 |
2002-08-06 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules for activating dendritic cells
|
|
US6239116B1
(en)
*
|
1994-07-15 |
2001-05-29 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US6207646B1
(en)
*
|
1994-07-15 |
2001-03-27 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
US20030026782A1
(en)
*
|
1995-02-07 |
2003-02-06 |
Arthur M. Krieg |
Immunomodulatory oligonucleotides
|
|
US7935675B1
(en)
*
|
1994-07-15 |
2011-05-03 |
University Of Iowa Research Foundation |
Immunostimulatory nucleic acid molecules
|
|
EP0909323B1
(en)
|
1996-01-04 |
2007-02-28 |
Novartis Vaccines and Diagnostics, Inc. |
Helicobacter pylori bacterioferritin
|
|
US6610661B1
(en)
|
1996-10-11 |
2003-08-26 |
The Regents Of The University Of California |
Immunostimulatory polynucleotide/immunomodulatory molecule conjugates
|
|
EP0855184A1
(en)
*
|
1997-01-23 |
1998-07-29 |
Grayson B. Dr. Lipford |
Pharmaceutical composition comprising a polynucleotide and an antigen especially for vaccination
|
|
EP1039935A4
(en)
|
1997-02-28 |
2005-04-27 |
Univ Iowa Res Found |
USE OF NUCLEIC ACIDS CONTAINING UNMETHYLATED CpG DINUCLEOTIDE IN THE TREATMENT OF LPS-ASSOCIATED DISORDERS
|
|
US6406705B1
(en)
*
|
1997-03-10 |
2002-06-18 |
University Of Iowa Research Foundation |
Use of nucleic acids containing unmethylated CpG dinucleotide as an adjuvant
|
|
EP1027033B1
(en)
|
1997-05-14 |
2009-07-22 |
The University Of British Columbia |
High efficiency encapsulation of nucleic acids in lipid vesicles
|
|
EP2085090A3
(en)
*
|
1997-06-06 |
2012-05-02 |
The Regents of the University of California |
Inhibitors of DNA immunostimulatory sequence activity
|
|
US6589940B1
(en)
|
1997-06-06 |
2003-07-08 |
Dynavax Technologies Corporation |
Immunostimulatory oligonucleotides, compositions thereof and methods of use thereof
|
|
WO1999001154A1
(en)
*
|
1997-07-03 |
1999-01-14 |
University Of Iowa Research Foundation |
Method for inhibiting immunostimulatory dna associated responses
|
|
PT1009413E
(pt)
*
|
1997-09-05 |
2007-05-31 |
Univ California |
Utilização de oligonucleótidos imumoestimulantes para a prevenção ou tratamento da asma.
|
|
WO2001031019A2
(en)
|
1999-10-29 |
2001-05-03 |
Chiron Spa |
Neisserial antigenic peptides
|
|
IL139813A0
(en)
*
|
1998-05-22 |
2002-02-10 |
Loeb Health Res Inst At The Ot |
Methods and products for inducing mucosal immunity
|
|
US6562798B1
(en)
|
1998-06-05 |
2003-05-13 |
Dynavax Technologies Corp. |
Immunostimulatory oligonucleotides with modified bases and methods of use thereof
|
|
AU773204C
(en)
|
1998-08-10 |
2005-05-19 |
Antigenics Llc |
Compositions of CPG and saponin adjuvants and methods thereof
|
|
AU6425999A
(en)
*
|
1998-10-09 |
2000-05-01 |
Dynavax Technologies Corporation |
Anti hiv compositions comprising immunostimulatory polynucleotides and hiv antigens
|
|
JP4812942B2
(ja)
*
|
1999-02-26 |
2011-11-09 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル |
CGモチーフを含むオリゴヌクレオチドを用いるNeisseria抗原殺菌活性の増強
|
|
US8206749B1
(en)
|
1999-02-26 |
2012-06-26 |
Novartis Vaccines And Diagnostics, Inc. |
Microemulsions with adsorbed macromolecules and microparticles
|
|
GB2348132B
(en)
*
|
1999-03-02 |
2004-08-04 |
Nedaa Abdul-Ghani Nasif |
Asthma/allergy therapy that targets t-lymphocytes and/or eosinophils
|
|
WO2000054803A2
(en)
*
|
1999-03-16 |
2000-09-21 |
Panacea Pharmaceuticals, Llc |
Immunostimulatory nucleic acids and antigens
|
|
FR2790955B1
(fr)
*
|
1999-03-19 |
2003-01-17 |
Assist Publ Hopitaux De Paris |
Utilisation d'oligonucleotides stabilises comme principe actif antitumoral
|
|
EP1176966B1
(en)
|
1999-04-12 |
2013-04-03 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES |
Oligodeoxynucleotide and its use to induce an immune response
|
|
US6977245B2
(en)
|
1999-04-12 |
2005-12-20 |
The United States Of America As Represented By The Department Of Health And Human Services |
Oligodeoxynucleotide and its use to induce an immune response
|
|
US6558670B1
(en)
|
1999-04-19 |
2003-05-06 |
Smithkline Beechman Biologicals S.A. |
Vaccine adjuvants
|
|
TR200103018T2
(tr)
|
1999-04-19 |
2002-02-21 |
Beecham Biologicals S.A. Smithkline |
İmmünostimülatör oligonükleotid ve saponin içeren katkı bileşikleri.
|
|
US6737066B1
(en)
|
1999-05-06 |
2004-05-18 |
The Immune Response Corporation |
HIV immunogenic compositions and methods
|
|
WO2000067787A2
(en)
*
|
1999-05-06 |
2000-11-16 |
The Immune Response Corporation |
Hiv immunogenic compositions and methods
|
|
DE60041335D1
(de)
|
1999-08-19 |
2009-02-26 |
Dynavax Tech Corp |
Methode zur modulierung eines immunantwortes mit immunstimulierenden sequencen und zusammensetzungen dafür
|
|
CZ20021029A3
(cs)
*
|
1999-08-27 |
2002-08-14 |
Inex Pharmaceuticals Corp. |
Kompozice a její pouľití pro stimulaci sekrece cytokinů a indukci imunitní odpovědi
|
|
US6949520B1
(en)
|
1999-09-27 |
2005-09-27 |
Coley Pharmaceutical Group, Inc. |
Methods related to immunostimulatory nucleic acid-induced interferon
|
|
US7223398B1
(en)
|
1999-11-15 |
2007-05-29 |
Dynavax Technologies Corporation |
Immunomodulatory compositions containing an immunostimulatory sequence linked to antigen and methods of use thereof
|
|
DE60131430T2
(de)
|
2000-01-14 |
2008-10-16 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Oligodeoxynukleotide und ihre verwendung zur induktion einer immunreaktion
|
|
US20010044416A1
(en)
*
|
2000-01-20 |
2001-11-22 |
Mccluskie Michael J. |
Immunostimulatory nucleic acids for inducing a Th2 immune response
|
|
US7585847B2
(en)
|
2000-02-03 |
2009-09-08 |
Coley Pharmaceutical Group, Inc. |
Immunostimulatory nucleic acids for the treatment of asthma and allergy
|
|
US20040131628A1
(en)
*
|
2000-03-08 |
2004-07-08 |
Bratzler Robert L. |
Nucleic acids for the treatment of disorders associated with microorganisms
|
|
US20020028784A1
(en)
*
|
2000-03-10 |
2002-03-07 |
Nest Gary Van |
Methods of preventing and treating viral infections using immunomodulatory polynucleotide sequences
|
|
US20020107212A1
(en)
*
|
2000-03-10 |
2002-08-08 |
Nest Gary Van |
Methods of reducing papillomavirus infection using immunomodulatory polynucleotide sequences
|
|
US20020098199A1
(en)
*
|
2000-03-10 |
2002-07-25 |
Gary Van Nest |
Methods of suppressing hepatitis virus infection using immunomodulatory polynucleotide sequences
|
|
US20010046967A1
(en)
*
|
2000-03-10 |
2001-11-29 |
Gary Van Nest |
Methods of preventing and treating respiratory viral infection using immunomodulatory polynucleotide
|
|
US20030129251A1
(en)
|
2000-03-10 |
2003-07-10 |
Gary Van Nest |
Biodegradable immunomodulatory formulations and methods for use thereof
|
|
US7129222B2
(en)
|
2000-03-10 |
2006-10-31 |
Dynavax Technologies Corporation |
Immunomodulatory formulations and methods for use thereof
|
|
US7157437B2
(en)
*
|
2000-03-10 |
2007-01-02 |
Dynavax Technologies Corporation |
Methods of ameliorating symptoms of herpes infection using immunomodulatory polynucleotide sequences
|
|
HU228264B1
(en)
|
2000-06-08 |
2013-02-28 |
Intercell Ag |
Immunostimulatory oligodeoxynucleotides
|
|
DE60139689D1
(de)
|
2000-06-22 |
2009-10-08 |
Univ Iowa Res Found |
Kombination von CpG und Antikörpern gegen CD19,CD20,CD22 oder CD40 zur Prävention oder Behandlung von Krebs.
|
|
EP1335741A4
(en)
*
|
2000-08-25 |
2005-10-26 |
Yeda Res & Dev |
METHOD FOR THE PREVENTION OF AUTOIMMUNE DISEASES WITH CpG-CONTAINING POLYNUCLEOTIDES (04.03.02)
|
|
IL154853A0
(en)
|
2000-10-27 |
2003-10-31 |
Chiron Spa |
Nucleic acids and proteins from streptococcus groups a & b
|
|
ES2307568T3
(es)
*
|
2000-12-08 |
2008-12-01 |
Coley Pharmaceutical Gmbh |
Acidos nucleicos de tipo cpg y metodos de uso de los mismos.
|
|
KR100881923B1
(ko)
|
2000-12-27 |
2009-02-04 |
다이나박스 테크놀로지 코퍼레이션 |
면역자극 폴리뉴클레오티드 및 그것의 사용 방법
|
|
WO2002094845A2
(en)
|
2001-05-21 |
2002-11-28 |
Intercell Ag |
Method for stabilising of nucleic acids
|
|
ES2356934T3
(es)
|
2001-06-05 |
2011-04-14 |
Curevac Gmbh |
ARNm ESTABILIZADO CON UN CONTENIDO DE G/C AUMENTADO QUE CODIFICA PARA UN ANTÍGENO VIRAL.
|
|
GB0115176D0
(en)
|
2001-06-20 |
2001-08-15 |
Chiron Spa |
Capular polysaccharide solubilisation and combination vaccines
|
|
AU2002345847B2
(en)
|
2001-06-21 |
2008-05-29 |
Dynavax Technologies Corporation |
Chimeric immunomodulatory compounds and methods of using the same
|
|
GB0118249D0
(en)
|
2001-07-26 |
2001-09-19 |
Chiron Spa |
Histidine vaccines
|
|
US7666674B2
(en)
|
2001-07-27 |
2010-02-23 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of sterically stabilized cationic liposomes to efficiently deliver CPG oligonucleotides in vivo
|
|
GB0121591D0
(en)
|
2001-09-06 |
2001-10-24 |
Chiron Spa |
Hybrid and tandem expression of neisserial proteins
|
|
AU2002318944A1
(en)
*
|
2001-08-01 |
2003-02-17 |
Coley Pharmaceutical Gmbh |
Methods and compositions relating to plasmacytoid dendritic cells
|
|
CA2456328C
(en)
*
|
2001-08-07 |
2015-05-26 |
Dynavax Technologies Corporation |
Complexes of a short cpg-containing oligonucleotide bound to the surface of a solid phase microcarrier and methods for use thereof
|
|
US7354909B2
(en)
*
|
2001-08-14 |
2008-04-08 |
The United States Of America As Represented By Secretary Of The Department Of Health And Human Services |
Method for rapid generation of mature dendritic cells
|
|
EP2196217A1
(en)
|
2001-09-14 |
2010-06-16 |
Cytos Biotechnology AG |
Packaging of immunostimulatory substances into virus-like particles: method of preparation and use
|
|
AR045702A1
(es)
|
2001-10-03 |
2005-11-09 |
Chiron Corp |
Composiciones de adyuvantes.
|
|
WO2003045316A2
(en)
|
2001-11-21 |
2003-06-05 |
The Board Of Trustees Of The Leland Stanford Junior University |
Polynucleotide therapy
|
|
DE10162480A1
(de)
|
2001-12-19 |
2003-08-07 |
Ingmar Hoerr |
Die Applikation von mRNA für den Einsatz als Therapeutikum gegen Tumorerkrankungen
|
|
US7615227B2
(en)
|
2001-12-20 |
2009-11-10 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of CpG oligodeoxynucleotides to induce angiogenesis
|
|
US8466116B2
(en)
|
2001-12-20 |
2013-06-18 |
The Unites States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Use of CpG oligodeoxynucleotides to induce epithelial cell growth
|
|
EP2572707A3
(en)
|
2002-02-20 |
2013-11-06 |
Novartis Vaccines and Diagnostics, Inc. |
Microparticles with adsorbed polypeptide-containing molecules
|
|
CA2388049A1
(en)
|
2002-05-30 |
2003-11-30 |
Immunotech S.A. |
Immunostimulatory oligonucleotides and uses thereof
|
|
AU2003243409A1
(en)
*
|
2002-06-05 |
2003-12-22 |
Coley Pharmaceutical Group, Inc. |
Method for treating autoimmune or inflammatory diseases with combinations of inhibitory oligonucleotides and small molecule antagonists of immunostimulatory cpg nucleic acids
|
|
US7605138B2
(en)
|
2002-07-03 |
2009-10-20 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7576066B2
(en)
|
2002-07-03 |
2009-08-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US20040053880A1
(en)
|
2002-07-03 |
2004-03-18 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
US7569553B2
(en)
|
2002-07-03 |
2009-08-04 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
DE10229872A1
(de)
|
2002-07-03 |
2004-01-29 |
Curevac Gmbh |
Immunstimulation durch chemisch modifizierte RNA
|
|
US7807803B2
(en)
|
2002-07-03 |
2010-10-05 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid compositions for stimulating immune responses
|
|
EP1551221A4
(en)
*
|
2002-07-03 |
2007-08-01 |
Coley Pharm Group Inc |
NUCLEIC ACID COMPOSITIONS FOR STIMULATING IMMUNE RESPONSES
|
|
US20050196379A1
(en)
*
|
2002-07-15 |
2005-09-08 |
Furman Philip A. |
Combination therapies with L-FMAU for the treatment of hepatitis B virus infection
|
|
NZ538628A
(en)
|
2002-08-12 |
2008-06-30 |
Dynavax Tech Corp |
Immunomodulatory compositions, methods of making, and methods of use thereof
|
|
GB0220194D0
(en)
|
2002-08-30 |
2002-10-09 |
Chiron Spa |
Improved vesicles
|
|
US8263091B2
(en)
*
|
2002-09-18 |
2012-09-11 |
The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of treating and preventing infections in immunocompromised subjects with immunostimulatory CpG oligonucleotides
|
|
CN101948835A
(zh)
|
2002-10-29 |
2011-01-19 |
科勒制药集团股份有限公司 |
Cpg寡核苷酸在治疗丙型肝炎病毒感染中的应用
|
|
CA2504493C
(en)
*
|
2002-11-01 |
2015-12-29 |
The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services |
Method of preventing infections from bioterrorism agents with immunostimulatory cpg oligonucleotides
|
|
WO2004046177A2
(en)
|
2002-11-15 |
2004-06-03 |
Chiron Srl |
Unexpected surface proteins in neisseria meningitidis
|
|
EP2329827A3
(en)
|
2002-11-21 |
2011-07-13 |
Bayhill Therapeutics, Inc. |
Methods and immune modulatory nucleic acid compositions for preventing and treating disease
|
|
GB0227346D0
(en)
|
2002-11-22 |
2002-12-31 |
Chiron Spa |
741
|
|
JP2006512927A
(ja)
|
2002-12-11 |
2006-04-20 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
5’cpg核酸およびその使用方法
|
|
EP1625140A4
(en)
|
2002-12-23 |
2008-06-18 |
Dynavax Tech Corp |
BRANCHED IMMUNOMODULAR COMPOUNDS AND METHOD OF USE THEREOF
|
|
CN101693890B
(zh)
|
2002-12-23 |
2012-09-05 |
戴纳伐克斯技术股份有限公司 |
免疫刺激序列寡核苷酸和使用方法
|
|
US8158768B2
(en)
|
2002-12-23 |
2012-04-17 |
Dynavax Technologies Corporation |
Immunostimulatory sequence oligonucleotides and methods of using the same
|
|
WO2004060396A2
(en)
|
2002-12-27 |
2004-07-22 |
Chiron Corporation |
Immunogenic compositions containing phospholpid
|
|
WO2004064759A2
(en)
|
2003-01-21 |
2004-08-05 |
Chiron Corporation |
Use of tryptanthrin compounds for immune potentiation
|
|
AU2004213855B2
(en)
|
2003-02-20 |
2010-03-04 |
University Of Connecticut Health Center |
Methods and compositions for the treatment of cancer and infectious disease using alpha (2) macroglobulin-antigenic molecule complexes
|
|
US7537767B2
(en)
|
2003-03-26 |
2009-05-26 |
Cytis Biotechnology Ag |
Melan-A- carrier conjugates
|
|
CN100560719C
(zh)
|
2003-03-26 |
2009-11-18 |
赛托斯生物技术公司 |
Melan-a肽类似物-病毒样颗粒偶联物
|
|
WO2004087153A2
(en)
|
2003-03-28 |
2004-10-14 |
Chiron Corporation |
Use of organic compounds for immunopotentiation
|
|
US20040235770A1
(en)
*
|
2003-04-02 |
2004-11-25 |
Coley Pharmaceutical Group, Ltd. |
Immunostimulatory nucleic acid oil-in-water formulations and related methods of use
|
|
CN1798563A
(zh)
*
|
2003-05-15 |
2006-07-05 |
独立行政法人科学技术振兴机构 |
免疫刺激剂
|
|
CA2525966A1
(en)
*
|
2003-05-15 |
2004-12-23 |
The Board Of Trustees Of The Leland Stanford Junior University |
Novel immunomodulating peptide
|
|
CA2528007C
(en)
|
2003-06-02 |
2012-03-27 |
Chiron Corporation |
Immunogenic compositions based on microparticles comprising adsorbed toxoid and a polysaccharide-containing antigen
|
|
US20060035242A1
(en)
|
2004-08-13 |
2006-02-16 |
Michelitsch Melissa D |
Prion-specific peptide reagents
|
|
CA2536139A1
(en)
|
2003-09-25 |
2005-04-07 |
Coley Pharmaceutical Group, Inc. |
Nucleic acid-lipophilic conjugates
|
|
US20050239733A1
(en)
*
|
2003-10-31 |
2005-10-27 |
Coley Pharmaceutical Gmbh |
Sequence requirements for inhibitory oligonucleotides
|
|
JP4817599B2
(ja)
*
|
2003-12-25 |
2011-11-16 |
独立行政法人科学技術振興機構 |
免疫活性増強剤とこれを用いた免疫活性の増強方法
|
|
JP3976742B2
(ja)
|
2004-02-27 |
2007-09-19 |
江守商事株式会社 |
インターフェロンアルファを誘導する免疫刺激オリゴヌクレオチド
|
|
TWI235440B
(en)
*
|
2004-03-31 |
2005-07-01 |
Advanced Semiconductor Eng |
Method for making leadless semiconductor package
|
|
US20110104186A1
(en)
|
2004-06-24 |
2011-05-05 |
Nicholas Valiante |
Small molecule immunopotentiators and assays for their detection
|
|
JP2008504292A
(ja)
|
2004-06-24 |
2008-02-14 |
ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド |
免疫増強用の化合物
|
|
JP2008514187A
(ja)
|
2004-09-01 |
2008-05-08 |
ダイナバックス テクノロジーズ コーポレイション |
先天性免疫応答及び自己免疫疾患の阻害法及び阻害用組成物
|
|
JP2008000001A
(ja)
*
|
2004-09-30 |
2008-01-10 |
Osaka Univ |
免疫刺激オリゴヌクレオチドおよびその医薬用途
|
|
WO2006055729A1
(en)
*
|
2004-11-16 |
2006-05-26 |
Transcutaneous Technologies Inc. |
Iontophoretic device and method for administering immune response-enhancing agents and compositions
|
|
JP2008524237A
(ja)
*
|
2004-12-17 |
2008-07-10 |
ダイナバックス テクノロジーズ コーポレイション |
免疫寛容の誘導又は促進のための方法及び組成物
|
|
JP4993750B2
(ja)
|
2005-01-27 |
2012-08-08 |
チルドレンズ ホスピタル アンド リサーチ センター アット オークランド |
髄膜炎菌に起因する疾患に対する広域防御のための、gna1870を基にした小胞ワクチン
|
|
CN101160401A
(zh)
*
|
2005-02-24 |
2008-04-09 |
科勒制药集团公司 |
免疫刺激寡核苷酸
|
|
SG160336A1
(en)
|
2005-03-04 |
2010-04-29 |
Dynavax Tech Corp |
Vaccines comprising oligonucleotides having immunostimulatory sequences (iss) wherein the iss are conjugated to antigens and stabilized by buffer conditions and further excipients
|
|
EP1865967A4
(en)
*
|
2005-04-08 |
2011-02-09 |
Chimerix Inc |
COMPOUNDS, COMPOSITIONS AND METHODS FOR TREATING VIRAL INFECTIONS AND OTHER DISEASES
|
|
WO2006110655A2
(en)
|
2005-04-08 |
2006-10-19 |
Chimerix, Inc. |
Compounds, compositions and methods for the treatment of poxvirus infections
|
|
KR20080066712A
(ko)
*
|
2005-09-30 |
2008-07-16 |
티티아이 엘뷰 가부시키가이샤 |
관능화된 미세바늘 경피 약물 전달 시스템, 장치 및 방법
|
|
EP1928539A1
(en)
*
|
2005-09-30 |
2008-06-11 |
Tti Ellebeau, Inc. |
Functionalized microneedles transdermal drug delivery systems, devices, and methods
|
|
KR20080080087A
(ko)
*
|
2005-09-30 |
2008-09-02 |
티티아이 엘뷰 가부시키가이샤 |
신규 약학 담체를 이용한 경피 약물 전달시스템, 장치 및방법
|
|
JP5484732B2
(ja)
|
2005-12-14 |
2014-05-07 |
サイトス バイオテクノロジー アーゲー |
過敏症の治療のための免疫賦活性核酸パッケージ粒子
|
|
JP2009525048A
(ja)
*
|
2006-02-01 |
2009-07-09 |
ザ ジョンズ ホプキンス ユニバーシティー |
腫瘍性障害または感染症に対する免疫学的予防法または免疫療法のためのポリペプチド−核酸複合体
|
|
CA2642152C
(en)
*
|
2006-02-15 |
2016-11-01 |
Coley Pharmaceutical Gmbh |
Compositions and methods for oligonucleotide formulations
|
|
ES2555544T3
(es)
|
2006-03-07 |
2016-01-04 |
Vaxinnate Corporation |
Composiciones que incluyen hemaglutinina, métodos de preparación y métodos de uso de las mismas
|
|
CN101460620B
(zh)
|
2006-05-31 |
2012-02-15 |
东丽株式会社 |
免疫刺激寡核苷酸及其药物用途
|
|
KR101552227B1
(ko)
|
2006-06-12 |
2015-09-10 |
사이토스 바이오테크놀로지 아게 |
올리고뉴클레오티드를 rna 박테리오파지의 바이러스-유사 입자로 패키징하는 방법
|
|
EP2032144A4
(en)
*
|
2006-06-13 |
2011-05-04 |
Bayhill Therapeutics Inc |
METHODS AND COMPOSITIONS BASED ON NUCLEIC ACID MODULATORS OF THE IMMUNE SYSTEM FOR THE PREVENTION AND TREATMENT OF DISEASE
|
|
DE102006035618A1
(de)
*
|
2006-07-31 |
2008-02-07 |
Curevac Gmbh |
Nukleinsäure der Formel (I): GlXmGn, insbesondere als immunstimulierendes Adjuvanz
|
|
AU2007280690C1
(en)
|
2006-07-31 |
2012-08-23 |
Curevac Gmbh |
Nucleic acid of formula (I): GIXmGn, or (II): CIXmCn, in particular as an immune-stimulating agent/adjuvant
|
|
CN104857512A
(zh)
|
2006-11-09 |
2015-08-26 |
戴纳瓦克斯技术公司 |
使用免疫刺激性寡核苷酸进行长期的疾病修饰
|
|
KR20100063048A
(ko)
*
|
2007-07-31 |
2010-06-10 |
더 존스 홉킨스 유니버시티 |
신생물성 또는 감염성 장애의 면역예방 또는 면역치료를 위한 폴리펩티드-핵산 접합체
|
|
EP2821488B1
(en)
*
|
2007-08-01 |
2016-07-27 |
Idera Pharmaceuticals, Inc. |
Novel synthetic agonists of TLR9
|
|
WO2009030254A1
(en)
|
2007-09-04 |
2009-03-12 |
Curevac Gmbh |
Complexes of rna and cationic peptides for transfection and for immunostimulation
|
|
EP2209896B1
(en)
|
2007-10-26 |
2017-03-01 |
Dynavax Technologies Corporation |
Methods and compositions for inhibition of immune responses and autoimmunity
|
|
RU2506275C2
(ru)
|
2007-11-01 |
2014-02-10 |
Астеллас Фарма Инк. |
Иммуносупрессорные полипептиды и нуклеиновые кислоты
|
|
ES2664753T3
(es)
|
2007-12-07 |
2018-04-23 |
Glaxosmithkline Biologicals Sa |
Composiciones de inducción de respuestas inmunes
|
|
CN101977610B
(zh)
*
|
2008-01-25 |
2012-05-16 |
奇默里克斯公司 |
治疗病毒感染的方法
|
|
CA2717870A1
(en)
|
2008-03-10 |
2009-09-17 |
Children's Hospital & Research Center At Oakland |
Chimeric factor h binding proteins (fhbp) containing a heterologous b domain and methods of use
|
|
AU2009236585B2
(en)
|
2008-04-18 |
2013-03-07 |
Vaxinnate Corporation |
Deletion mutants of flagellin and methods of use
|
|
CA2724418A1
(en)
|
2008-05-15 |
2009-11-19 |
Dynavax Technologies Corporation |
Long term disease modification using immunostimulatory oligonucleotides
|
|
GB0809476D0
(en)
*
|
2008-05-23 |
2008-07-02 |
Cambridge Entpr Ltd |
Treatment of neurodegenerative disorders
|
|
LT3056214T
(lt)
|
2008-06-27 |
2019-06-10 |
Zoetis Services Llc |
Naujos adjuvantų kompozicijos
|
|
WO2010037408A1
(en)
|
2008-09-30 |
2010-04-08 |
Curevac Gmbh |
Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
|
|
MX337723B
(es)
|
2008-12-09 |
2016-03-15 |
Pfizer Vaccines Llc |
Vacuna de peptido ch3 de ige.
|
|
EP2384120B1
(en)
|
2009-01-05 |
2019-12-11 |
Epitogenesis Inc. |
Adjuvant compositions and methods of use
|
|
CN103800906B
(zh)
|
2009-03-25 |
2017-09-22 |
德克萨斯大学系统董事会 |
用于刺激哺乳动物对病原体的先天免疫抵抗力的组合物
|
|
US8614200B2
(en)
|
2009-07-21 |
2013-12-24 |
Chimerix, Inc. |
Compounds, compositions and methods for treating ocular conditions
|
|
RU2518291C2
(ru)
|
2009-07-30 |
2014-06-10 |
Пфайзер Вэксинс ЭлЭлСи |
Антигенные tau-пептиды и их применения
|
|
MY163512A
(en)
|
2009-09-03 |
2017-09-15 |
Pfizer Vaccines Llc |
Pcsk9 vaccine
|
|
US20110053829A1
(en)
|
2009-09-03 |
2011-03-03 |
Curevac Gmbh |
Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
|
|
WO2011054893A2
(en)
|
2009-11-05 |
2011-05-12 |
Novartis Ag |
Biomarkers predictive of progression of fibrosis
|
|
NZ600978A
(en)
|
2009-12-22 |
2014-08-29 |
Celldex Therapeutics Inc |
Vaccine compositions
|
|
DK2534150T3
(en)
|
2010-02-12 |
2017-06-12 |
Chimerix Inc |
METHODS OF TREATING VIRUS INFECTION
|
|
CA2792258A1
(en)
|
2010-03-05 |
2011-09-09 |
President And Fellows Of Harvard College |
Induced dendritic cell compositions and uses thereof
|
|
TR201802933T4
(tr)
|
2010-03-30 |
2018-03-21 |
Childrens Hospital & Res Center At Oakland |
Özellikleri değiştirilmiş faktör h bağlama proteinleri (fhbp) ve bunların kullanım yöntemi.
|
|
WO2011139709A2
(en)
|
2010-04-26 |
2011-11-10 |
Chimerix, Inc. |
Methods of treating retroviral infections and related dosage regimes
|
|
WO2011154863A1
(en)
|
2010-06-07 |
2011-12-15 |
Pfizer Inc. |
Her-2 peptides and vaccines
|
|
WO2011154878A1
(en)
|
2010-06-07 |
2011-12-15 |
Pfizer Vaccines Llc |
Ige ch3 peptide vaccine
|
|
US8940310B2
(en)
|
2010-06-16 |
2015-01-27 |
Dynavax Technologies Corporation |
Methods of treatment using TLR7 and/or TLR9 inhibitors
|
|
CN107648604A
(zh)
|
2010-07-30 |
2018-02-02 |
库瑞瓦格股份公司 |
聚合物载体运载物复合物及聚合物载体的用途
|
|
US8822663B2
(en)
|
2010-08-06 |
2014-09-02 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
RS63430B1
(sr)
|
2010-10-01 |
2022-08-31 |
Modernatx Inc |
Ribonukleinske kiseline koje sadrže n1-metil-pseudouracile i njihove primene
|
|
US20140004142A1
(en)
|
2011-03-02 |
2014-01-02 |
Pfizer Inc. |
Pcsk9 vaccine
|
|
EP2691101A2
(en)
|
2011-03-31 |
2014-02-05 |
Moderna Therapeutics, Inc. |
Delivery and formulation of engineered nucleic acids
|
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
|
DK3682905T3
(da)
|
2011-10-03 |
2022-02-28 |
Modernatx Inc |
Modificerede nukleosider, nukleotider og nukleinsyrer og anvendelser deraf
|
|
DE12858350T1
(de)
|
2011-12-16 |
2021-10-07 |
Modernatx, Inc. |
Modifizierte mrna zusammensetzungen
|
|
WO2013113326A1
(en)
|
2012-01-31 |
2013-08-08 |
Curevac Gmbh |
Pharmaceutical composition comprising a polymeric carrier cargo complex and at least one protein or peptide antigen
|
|
HK1206601A1
(en)
|
2012-04-02 |
2016-01-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of biologics and proteins associated with human disease
|
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
|
US9878056B2
(en)
|
2012-04-02 |
2018-01-30 |
Modernatx, Inc. |
Modified polynucleotides for the production of cosmetic proteins and peptides
|
|
NZ701324A
(en)
|
2012-05-04 |
2016-09-30 |
Pfizer |
Prostate-associated antigens and vaccine-based immunotherapy regimens
|
|
US9868955B2
(en)
|
2012-09-29 |
2018-01-16 |
Dynavax Technologies Corporation |
Human toll-like receptor inhibitors and methods of use thereof
|
|
US9228184B2
(en)
|
2012-09-29 |
2016-01-05 |
Dynavax Technologies Corporation |
Human toll-like receptor inhibitors and methods of use thereof
|
|
HRP20220607T1
(hr)
|
2012-11-26 |
2022-06-24 |
Modernatx, Inc. |
Terminalno modificirana rna
|
|
JP2016507520A
(ja)
|
2013-01-23 |
2016-03-10 |
ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー |
安定化されたb型肝炎コアポリペプチド
|
|
CA2906198C
(en)
|
2013-03-14 |
2022-11-29 |
Andes Biotechnologies S.A. |
Antisense oligonucleotides for treatment of cancer stem cells
|
|
US10066269B2
(en)
|
2013-03-14 |
2018-09-04 |
Andes Biotechnologies Global, Inc. |
Methods for detecting and treating multiple myeloma
|
|
ES2762631T3
(es)
|
2013-03-14 |
2020-05-25 |
Harvard College |
Composiciones a base de nanopartículas
|
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
|
WO2014151994A1
(en)
|
2013-03-15 |
2014-09-25 |
Kambiz Shekdar |
Genome editing using effector oligonucleotides for therapeutic treatment
|
|
WO2015132619A1
(en)
|
2013-05-15 |
2015-09-11 |
The Governors Of The University Of Alberta |
E1e2 hcv vaccines and methods of use
|
|
WO2015024668A2
(en)
|
2013-08-21 |
2015-02-26 |
Curevac Gmbh |
Respiratory syncytial virus (rsv) vaccine
|
|
WO2015042369A2
(en)
|
2013-09-19 |
2015-03-26 |
Zoetis Llc |
Oil-based adjuvants
|
|
WO2015048744A2
(en)
|
2013-09-30 |
2015-04-02 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding immune modulating polypeptides
|
|
WO2015051214A1
(en)
|
2013-10-03 |
2015-04-09 |
Moderna Therapeutics, Inc. |
Polynucleotides encoding low density lipoprotein receptor
|
|
MY196581A
(en)
|
2013-11-01 |
2023-04-19 |
Pfizer |
Vectors for Expression of Prostate-Associated Antigens
|
|
WO2015062738A1
(en)
|
2013-11-01 |
2015-05-07 |
Curevac Gmbh |
Modified rna with decreased immunostimulatory properties
|
|
US10279019B2
(en)
|
2014-02-11 |
2019-05-07 |
Stc.Unm |
PCSK9 peptide vaccine conjugated to a Qbeta carrier and methods of using the same
|
|
CA2936286A1
(en)
|
2014-04-01 |
2015-10-08 |
Curevac Ag |
Polymeric carrier cargo complex for use as an immunostimulating agent or as an adjuvant
|
|
WO2016044839A2
(en)
|
2014-09-19 |
2016-03-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
|
DK3244920T5
(da)
|
2015-01-16 |
2024-10-07 |
Zoetis Services Llc |
Mund- og klovsyge-vaccine
|
|
KR20180014009A
(ko)
|
2015-05-29 |
2018-02-07 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 cpg-c 유형 올리고뉴클레오티드의 조합
|
|
EP3341017B1
(en)
|
2015-08-25 |
2024-10-16 |
Babita Agrawal |
Immunomodulatory compositions comprising caulobacter crescentus and use thereof
|
|
WO2017060857A1
(en)
|
2015-10-08 |
2017-04-13 |
The Governors Of The University Of Alberta |
Hepatitis c virus e1/e2 heterodimers and methods of producing same
|
|
PT3405212T
(pt)
|
2016-01-19 |
2020-08-25 |
Pfizer |
Vacinas para o cancro
|
|
JP7034951B2
(ja)
*
|
2016-06-08 |
2022-03-14 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
操作されたウイルスベクターは炎症および免疫応答の誘導を低減する
|
|
IL266562B2
(en)
|
2016-11-09 |
2024-11-01 |
Univ Texas |
Pharmaceutical compositions for adaptive immune modulation for use in a subject susceptible to allergen induced asthma
|
|
EP3707262A1
(en)
*
|
2017-11-08 |
2020-09-16 |
President and Fellows of Harvard College |
Compositions and methods for inhibiting viral vector-induced inflammatory responses
|
|
US11633471B2
(en)
|
2018-03-06 |
2023-04-25 |
Unm Rainforest Innovations |
Compositions and methods for reducing serum triglycerides
|
|
US11987795B2
(en)
|
2020-11-24 |
2024-05-21 |
The Broad Institute, Inc. |
Methods of modulating SLC7A11 pre-mRNA transcripts for diseases and conditions associated with expression of SLC7A11
|
|
US20240299510A1
(en)
|
2020-12-31 |
2024-09-12 |
The United States Of America,As Represented By The Secretary,Department Of Health And Human Services |
Antibody-guided pcsk9-mimicking immunogens lacking 9-residue sequence overlap with human proteins
|
|
JPWO2022196699A1
(enExample)
|
2021-03-16 |
2022-09-22 |
|
|
|
JPWO2022196701A1
(enExample)
|
2021-03-16 |
2022-09-22 |
|
|
|
WO2023081486A1
(en)
|
2021-11-08 |
2023-05-11 |
Nurix Therapeutics, Inc. |
Toll-like receptor therapy combinations with cbl-b inhibitor compounds
|