JP2002503674A5 - - Google Patents
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- Publication number
- JP2002503674A5 JP2002503674A5 JP2000531467A JP2000531467A JP2002503674A5 JP 2002503674 A5 JP2002503674 A5 JP 2002503674A5 JP 2000531467 A JP2000531467 A JP 2000531467A JP 2000531467 A JP2000531467 A JP 2000531467A JP 2002503674 A5 JP2002503674 A5 JP 2002503674A5
- Authority
- JP
- Japan
- Prior art keywords
- chemical
- compound according
- nrr
- ring
- nhr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1998/002891 WO1999041276A1 (en) | 1998-02-12 | 1998-02-12 | β-SHEET MIMETICS AND METHODS RELATING TO THE USE THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2002503674A JP2002503674A (ja) | 2002-02-05 |
| JP2002503674A5 true JP2002503674A5 (https=) | 2005-12-22 |
Family
ID=22266392
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000531467A Pending JP2002503674A (ja) | 1998-02-12 | 1998-02-12 | βシート模倣物およびその使用に関する方法 |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1053246B1 (https=) |
| JP (1) | JP2002503674A (https=) |
| KR (1) | KR20010040939A (https=) |
| AT (1) | ATE230414T1 (https=) |
| AU (1) | AU748887B2 (https=) |
| CA (1) | CA2319766A1 (https=) |
| DE (1) | DE69810513T2 (https=) |
| ES (1) | ES2192764T3 (https=) |
| WO (1) | WO1999041276A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1261611A2 (en) * | 2000-02-29 | 2002-12-04 | Bristol-Myers Squibb Pharma Company | Inhibitors of hepatitis c virus ns3 protease |
| US6534651B2 (en) | 2000-04-06 | 2003-03-18 | Inotek Pharmaceuticals Corp. | 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof |
| US20060276497A1 (en) | 2000-05-09 | 2006-12-07 | Cephalon, Inc. | Novel multicyclic compounds and the use thereof |
| US7122679B2 (en) | 2000-05-09 | 2006-10-17 | Cephalon, Inc. | Multicyclic compounds and the use thereof |
| AU2003219809A1 (en) * | 2002-02-14 | 2003-09-04 | Myriad Genetics, Inc. | Beta-sheet mimetics and composition and methods relating thereto |
| ES2408932T3 (es) | 2008-06-25 | 2013-06-24 | Merck Sharp & Dohme Corp. | Síntesis y uso de agentes antibacterianos heterocíclicos |
| MX378266B (es) | 2014-10-06 | 2025-03-10 | Lighthouse Pharmaceuticals Inc | Inhibidores de gingipaina de lisina. |
| CN108602787A (zh) | 2015-11-09 | 2018-09-28 | 库特克希米公司 | 精氨酸牙龈卟啉菌蛋白酶的抑制剂 |
| HUE057289T2 (hu) | 2016-08-31 | 2022-05-28 | Jiangsu Hengrui Medicine Co | Oxopikolinamid-származék, annak elõállítási módszere és gyógyszerészeti felhasználása |
| CN109983012B (zh) | 2016-09-16 | 2023-12-01 | 莱特豪斯制药公司 | 赖氨酸牙龈蛋白酶的酮抑制剂 |
| WO2020007256A1 (zh) | 2018-07-02 | 2020-01-09 | 江苏恒瑞医药股份有限公司 | 一种氧代吡啶酰胺类衍生物的晶型及制备方法 |
| CN116120240A (zh) | 2019-09-27 | 2023-05-16 | 深圳信立泰药业股份有限公司 | FXIa抑制剂化合物及其制备方法和医药用途 |
| KR20260032556A (ko) | 2023-06-30 | 2026-03-09 | 심천 사루브리스 퍼머수티칼스 컴퍼니 리미티드 | 다치환된 거대환식 화합물 및 이의 제조 방법과 용도 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69317764T2 (de) * | 1992-02-14 | 1998-07-30 | Merrell Pharmaceuticals Inc., Cincinnati, Ohio | Aminoacetylmercaptoacetylamid derivate mit enkephalinase- und ace-hemmwirkung |
| WO1993023403A1 (en) * | 1992-05-15 | 1993-11-25 | Merrell Dow Pharmaceuticals Inc. | NOVEL MERCAPTOACETYLAMIDO PYRIDAZO[1,2]PYRIDAZINE, PYRAZOLO[1,2]PYRIDAZINE, PYRIDAZO[1,2-a][1,2]DIAZEPINE AND PYRAZOLO[1,2-a][1,2]DIAZEPINE DERIVATIVES USEFUL AS INHIBITORS OF ENKEPHALINASE AND ACE |
| EP0618223A3 (en) * | 1993-03-08 | 1996-06-12 | Sandoz Ltd | Peptides, the release of Interleukin 1-Bêta, useful as anti-inflammatory agents. |
| AP9701004A0 (en) * | 1994-12-22 | 1997-07-31 | Iaf Biochem Int | Low molecular weight bicyclic thrombin inhibitors. |
| JPH10508034A (ja) * | 1995-03-24 | 1998-08-04 | モレキュメティックス リミテッド | βシート模倣物および生物学的に活性なペプチドまたはタンパク質のインヒビターとしてのその使用 |
| WO1996030396A1 (en) * | 1995-03-24 | 1996-10-03 | Molecumetics Ltd. | β-SHEET MIMETICS AND USE THEREOF AS PROTEASE INHIBITORS |
| US5877313A (en) * | 1995-05-17 | 1999-03-02 | Bristol-Myers Squibb | Benzo-fused azepinone and piperidinone compounds useful in the inhibition of ACE and NEP |
| IT1277405B1 (it) * | 1995-08-01 | 1997-11-10 | Menarini Farma Ind | Derivati di lattami biciclici come inibitori della trombina |
| NZ334227A (en) * | 1996-08-05 | 2000-10-27 | Molecumetics Ltd | Use of beta-sheet mimetics as protease and kinase inhibitors and as inhibitors of transcription factors |
-
1998
- 1998-02-12 DE DE69810513T patent/DE69810513T2/de not_active Expired - Lifetime
- 1998-02-12 JP JP2000531467A patent/JP2002503674A/ja active Pending
- 1998-02-12 KR KR1020007008856A patent/KR20010040939A/ko not_active Ceased
- 1998-02-12 CA CA002319766A patent/CA2319766A1/en not_active Abandoned
- 1998-02-12 AU AU66557/98A patent/AU748887B2/en not_active Ceased
- 1998-02-12 EP EP98908551A patent/EP1053246B1/en not_active Expired - Lifetime
- 1998-02-12 ES ES98908551T patent/ES2192764T3/es not_active Expired - Lifetime
- 1998-02-12 AT AT98908551T patent/ATE230414T1/de not_active IP Right Cessation
- 1998-02-12 WO PCT/US1998/002891 patent/WO1999041276A1/en not_active Ceased
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