JP2001527517A - 血液、ウイルス性および細胞性疾患の治療組成物 - Google Patents

血液、ウイルス性および細胞性疾患の治療組成物

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Publication number
JP2001527517A
JP2001527517A JP50893198A JP50893198A JP2001527517A JP 2001527517 A JP2001527517 A JP 2001527517A JP 50893198 A JP50893198 A JP 50893198A JP 50893198 A JP50893198 A JP 50893198A JP 2001527517 A JP2001527517 A JP 2001527517A
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JP
Japan
Prior art keywords
acid
cells
treatment
cell
virus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP50893198A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001527517A5 (https=
Inventor
スーザン・ピー・ペリーネ
ダグラス・ヴィー・フォーラー
ブライアン・エフ・ホワイト
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Individual
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Individual
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Filing date
Publication date
Priority claimed from US08/687,671 external-priority patent/US6197743B1/en
Priority claimed from US08/687,670 external-priority patent/US5939456A/en
Application filed by Individual filed Critical Individual
Publication of JP2001527517A publication Critical patent/JP2001527517A/ja
Publication of JP2001527517A5 publication Critical patent/JP2001527517A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP50893198A 1996-07-26 1997-07-28 血液、ウイルス性および細胞性疾患の治療組成物 Pending JP2001527517A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/687,671 US6197743B1 (en) 1996-07-26 1996-07-26 Compositions and methods for the treatment of viral disorders
US08/687,671 1996-07-26
US08/687,670 US5939456A (en) 1996-07-26 1996-07-26 Pulsed administration of compositions for the treatment of blood disorders
US08/687,670 1996-07-26
PCT/US1997/012818 WO1998004290A2 (en) 1996-07-26 1997-07-28 Compositions comprising an inducing agent and an anti-viral agent for the treatment of blood, viral and cellular disorders

Publications (2)

Publication Number Publication Date
JP2001527517A true JP2001527517A (ja) 2001-12-25
JP2001527517A5 JP2001527517A5 (https=) 2005-04-07

Family

ID=27104047

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50893198A Pending JP2001527517A (ja) 1996-07-26 1997-07-28 血液、ウイルス性および細胞性疾患の治療組成物

Country Status (5)

Country Link
EP (4) EP1886677A1 (https=)
JP (1) JP2001527517A (https=)
AU (1) AU3889197A (https=)
CA (1) CA2263675C (https=)
WO (1) WO1998004290A2 (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008099730A1 (ja) * 2007-02-14 2008-08-21 Kaneka Corporation 光学活性な２－（アロイルオキシ）プロピオン酸を用いたアミン化合物の製造方法
JP2011509253A (ja) * 2008-01-08 2011-03-24 アクセリア ファーマシューティカルズ 抗菌ペプチド系に対する作動薬
JP2022525339A (ja) * 2019-03-14 2022-05-12 ヘモシアー セラピューティクス，インコーポレイティド 有機酸血症の治療方法

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US7910624B1 (en) 1995-03-03 2011-03-22 The Trustees Of Boston University Compositions for the treatment of blood disorders
AU774861B2 (en) 1998-02-11 2004-07-08 Douglas V Faller Compositions and methods for the treatment of cystic fibrosis
AU2685399A (en) * 1998-03-26 1999-10-18 Julianna Lisziewicz Method of rendering a human immunodeficiency virus population replication incompetent (in vivo)
DE19839566C2 (de) * 1998-08-31 2002-01-17 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten in der Transplantationsmedizin
DE19853487A1 (de) 1998-11-19 2000-05-25 Fumapharm Ag Muri Verwendung von Dialkylfumaraten
KR100788970B1 (ko) * 1999-11-05 2007-12-27 에미스페어 테크놀로지스, 인코포레이티드 활성제 전달용 페녹시 카르복시산 화합물 및 조성물
DE10000577A1 (de) 2000-01-10 2001-07-26 Fumapharm Ag Muri Verwendung von Fumarsäurederivaten zur Behandlung mitochondrialer Krankheiten
GB0008966D0 (en) 2000-04-13 2000-05-31 Imp College Innovations Ltd Vectors for gene therapy
WO2001082927A1 (en) * 2000-05-02 2001-11-08 Lead Chemical Co., Ltd Antibiral compositions containing phorbol derivatives as the main active ingredient
HU230252B1 (hu) 2001-01-12 2015-11-30 Biogen Idec International Gmbh Fumársav-amid származékok
DE10101307A1 (de) * 2001-01-12 2002-08-01 Fumapharm Ag Muri Fumarsäurederivate als NF-kappaB-Inhibitor
SI1663197T1 (sl) 2003-09-09 2008-06-30 Biogen Idec Internat Gmbh Uporaba derivatov fumarne kisline za zdravljenje sräśne insuficience in astme
GB0413702D0 (en) 2004-06-18 2004-07-21 Molmed Spa Thymidine kinase
LT2801354T (lt) 2004-10-08 2017-06-26 Forward Pharma A/S Kontroliuojamo atpalaidavimo farmacinės kompozicijos, apimančios fumaro rūgšties esterį
EP1915334A2 (en) * 2005-07-07 2008-04-30 Aditech Pharma AB Novel salts of fumaric acid monoalkylesters and their pharmaceutical use
GB0603041D0 (en) 2006-02-15 2006-03-29 Angeletti P Ist Richerche Bio Therapeutic compounds
EP2046736B1 (en) * 2006-07-27 2019-06-12 Emisphere Technologies, Inc. Arylsulfanyl compounds and compositions for delivering active agents
AR064777A1 (es) 2007-01-10 2009-04-22 Inst Di Reserche D Biolog Mole Indazoles sustituidos con amida como inhibidores de poli (adp- ribosa) polimerasa (parp)
EP2680006A1 (en) 2007-02-08 2014-01-01 Biogen Idec MA Inc. Treatment for Amyotrophic Lateral Sclerosis
WO2008128299A1 (en) * 2007-04-24 2008-10-30 Murdoch Childrens Research Institute Therapeutic protocol for treating hemoglobinopathy
EP2276478A4 (en) * 2008-04-11 2012-03-07 Aids Res Alliance METHOD FOR THE ADMINISTRATION OF PROSTRATIN AND STRUCTURAL ANALOGUE THEREOF
WO2010079222A1 (en) 2009-01-09 2010-07-15 Forward Pharma A/S Pharmaceutical formulation comprising one or more fumaric acid esters in an erosion matrix
US20110086869A1 (en) 2009-09-24 2011-04-14 The Trustees Of Boston University Methods for treating viral disorders
WO2011072086A1 (en) * 2009-12-08 2011-06-16 Hemaquest Pharmaceuticals, Inc. Methods and low dose regimens for treating red blood cell disorders
US20110245154A1 (en) * 2010-03-11 2011-10-06 Hemaquest Pharmaceuticals, Inc. Methods and Compositions for Treating Viral or Virally-Induced Conditions
JP2013523795A (ja) 2010-04-06 2013-06-17 バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー 植物のストレス耐性を増強させるための４−フェニル酪酸及び／又はその塩の使用
KR101293620B1 (ko) 2011-08-19 2013-08-13 국립암센터 트랜스-스플라이싱 라이보자임 및 암치료 유전자를 포함하는 재조합 아데노바이러스 및 이의 용도
BR112015022854A2 (pt) 2013-03-14 2017-07-18 Alkermes Pharma Ireland Ltd pró-farmacos de fumaratos e uso do mesmo no tratamento de várias doenças
US8669281B1 (en) 2013-03-14 2014-03-11 Alkermes Pharma Ireland Limited Prodrugs of fumarates and their use in treating various diseases
JP6337135B2 (ja) 2014-02-24 2018-06-06 アルカーメス ファーマ アイルランド リミテッド フマル酸エステルのスルホンアミドプロドラッグ及びスルフィンアミドプロドラッグ並びに種々の疾患の治療におけるその使用
GB2567093A (en) 2016-07-15 2019-04-03 Viracta Therapeutics Inc Histone deacetylase inhibitors for use in immunotherapy
WO2018140934A1 (en) * 2017-01-30 2018-08-02 The Children's Hospital Of Philadelphia Compositions and methods for hemoglobin production
US12419884B2 (en) 2018-08-06 2025-09-23 Brigham Young University Compositions and methods for treating iron overload
EP3930757A1 (en) 2019-03-01 2022-01-05 President And Fellows Of Harvard College Methods and compositions for protein delivery
CA3142142A1 (en) 2019-05-31 2020-12-03 Viracta Subsidiary, Inc. Methods of treating virally associated cancers with histone deacetylase inhibitors
AU2021336289A1 (en) * 2020-09-01 2023-05-04 I2O Therapeutics, Inc. Ionic liquid formulations for treating diabetes
CN113621577B (zh) * 2021-08-05 2023-03-10 河南普诺易生物制品研究院有限公司 人源化hek293细胞系表达重组蛋白用培养基添加剂、重组乙肝疫苗、表达方法
EP4429704A4 (en) 2021-11-10 2025-11-05 I2O Therapeutics Inc IONIC LIQUID COMPOSITIONS
CN120241679B (zh) * 2025-03-06 2025-12-05 华南农业大学 方酸类化合物在制备抗弓形虫病药物中的应用

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JPS5813512A (ja) * 1981-07-03 1983-01-26 シャルル・シャニ Ｃ↓１−ｃ↓６カルボン酸と塩基性アミノ酸との反応生成物を含む薬剤
EP0324574A2 (en) * 1988-01-13 1989-07-19 Arizona Board Of Regents Immunomodulating bryostatins
JPH04501123A (ja) * 1989-08-01 1992-02-27 ザ　ユニヴァーシティ　オブ　ミシガン 脱水／水補給リポソームに被嚢されたペプチド／タンパク質の局所送達
WO1993004683A1 (en) * 1991-09-12 1993-03-18 American Cyanamid Company Method of treating latent herpes viral infections
WO1995010271A2 (en) * 1993-10-12 1995-04-20 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Phenylacetate and derivatives alone or in combination with other compounds against neoplastic conditions and other disorders
WO1995011699A1 (en) * 1993-10-29 1995-05-04 The Trustees Of Boston University Physiologically stable compositions of butyric acid, and butyric acid salts and derivatives as anti-neoplastic agents
WO1996002244A1 (en) * 1994-07-20 1996-02-01 Agis Industries (1983) Ltd. A topical preparation for the prevention and treatment of lesions and sores associated with a herpes virus

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008099730A1 (ja) * 2007-02-14 2008-08-21 Kaneka Corporation 光学活性な２－（アロイルオキシ）プロピオン酸を用いたアミン化合物の製造方法
JP2011509253A (ja) * 2008-01-08 2011-03-24 アクセリア ファーマシューティカルズ 抗菌ペプチド系に対する作動薬
JP2022525339A (ja) * 2019-03-14 2022-05-12 ヘモシアー セラピューティクス，インコーポレイティド 有機酸血症の治療方法

Also Published As

Publication number Publication date
CA2263675A1 (en) 1998-02-05
EP1886677A1 (en) 2008-02-13
EP2298350A2 (en) 2011-03-23
WO1998004290A3 (en) 1998-08-13
CA2263675C (en) 2010-04-13
AU3889197A (en) 1998-02-20
WO1998004290A2 (en) 1998-02-05
EP1611885A1 (en) 2006-01-04
EP0969869A2 (en) 2000-01-12
EP1611885A8 (en) 2007-10-24
EP2298350A3 (en) 2011-06-08

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