JP2001526694A5 - - Google Patents
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- Publication number
- JP2001526694A5 JP2001526694A5 JP1999500114A JP50011499A JP2001526694A5 JP 2001526694 A5 JP2001526694 A5 JP 2001526694A5 JP 1999500114 A JP1999500114 A JP 1999500114A JP 50011499 A JP50011499 A JP 50011499A JP 2001526694 A5 JP2001526694 A5 JP 2001526694A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9711125.6 | 1997-05-29 | ||
| GBGB9711125.6A GB9711125D0 (en) | 1997-05-29 | 1997-05-29 | Novel cyanoguanidines |
| PCT/DK1998/000196 WO1998054144A1 (en) | 1997-05-29 | 1998-05-15 | Cyanoguanidines as cell proliferation inhibitors |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2001526694A JP2001526694A (ja) | 2001-12-18 |
| JP2001526694A5 true JP2001526694A5 (https=) | 2005-12-08 |
| JP4408455B2 JP4408455B2 (ja) | 2010-02-03 |
Family
ID=10813255
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50011499A Expired - Lifetime JP4408455B2 (ja) | 1997-05-29 | 1998-05-15 | 細胞増殖抑制剤としてのシアノグアニジン |
Country Status (20)
| Country | Link |
|---|---|
| US (1) | US6346541B1 (https=) |
| EP (1) | EP0984938B1 (https=) |
| JP (1) | JP4408455B2 (https=) |
| KR (1) | KR100496220B1 (https=) |
| CN (1) | CN1116283C (https=) |
| AT (1) | ATE249438T1 (https=) |
| AU (1) | AU733142B2 (https=) |
| CA (1) | CA2292895C (https=) |
| CZ (1) | CZ294842B6 (https=) |
| DE (1) | DE69818041T2 (https=) |
| DK (1) | DK0984938T3 (https=) |
| ES (1) | ES2206932T3 (https=) |
| GB (1) | GB9711125D0 (https=) |
| HU (1) | HUP0002921A3 (https=) |
| NZ (1) | NZ501071A (https=) |
| PL (1) | PL190314B1 (https=) |
| PT (1) | PT984938E (https=) |
| RO (1) | RO120541B1 (https=) |
| RU (1) | RU2195453C2 (https=) |
| WO (1) | WO1998054144A1 (https=) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9711123D0 (en) * | 1997-05-29 | 1997-07-23 | Leo Pharm Prod Ltd | Novel cyanoguanidines |
| WO2000061561A1 (en) | 1999-04-09 | 2000-10-19 | Shionogi Bioresearch Corp. | Cyanoguanidine compounds |
| AU1494702A (en) | 2000-11-21 | 2002-06-03 | Leo Pharma As | Cyanoguanidine prodrugs |
| US20030045515A1 (en) * | 2001-05-24 | 2003-03-06 | Lise Binderup | Combination medicament for treatment of neoplastic diseases |
| ATE442362T1 (de) * | 2001-05-24 | 2009-09-15 | Leo Pharma As | Pyridylcyanoguanidin verbindungen |
| US7253193B2 (en) | 2002-05-17 | 2007-08-07 | Leo Pharma A/S | Cyanoguanidine prodrugs |
| BR0309988A (pt) * | 2002-05-17 | 2005-02-22 | Leo Pharma As | Composto, composição farmacêutica, métodos para tratar ou melhorar doenças ou condições proliferativas e doenças inflamatórias, e, uso de um composto |
| CA2485351C (en) * | 2002-05-17 | 2011-12-06 | Leo Pharma A/S | Cyanoguanidine prodrugs |
| WO2006037468A1 (en) * | 2004-09-30 | 2006-04-13 | Istituto Di Ricerche Di Biologia Molecolare P Angeletti Spa | Hiv reverse transcriptase inhibitors |
| ES2572777T3 (es) | 2004-12-22 | 2016-06-02 | Leo Pharma A/S | Compuestos novedosos de cianoguanidina |
| US7423042B2 (en) * | 2005-03-25 | 2008-09-09 | Glaxo Group Limited | Compounds |
| US8173677B2 (en) | 2007-09-26 | 2012-05-08 | Gemin X Pharmaceuticals Canada Inc. | Compositions and methods for effecting NAD+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
| WO2009072004A2 (en) | 2007-09-26 | 2009-06-11 | Gemin X Pharmaceuticals Canada, Inc. | Compositions and methods for effecting nad+ levels using a nicotinamide phosphoribosyl transferase inhibitor |
| WO2009086835A1 (en) * | 2008-01-11 | 2009-07-16 | Topotarget A/S | Novel cyanoguanidines |
| RU2011111728A (ru) | 2008-08-29 | 2012-10-10 | Топотаргет А/С (Dk) | Новые производные мочевины и тиомочевины |
| CA2751495C (en) | 2009-02-06 | 2013-08-20 | Tianjin Hemay Bio-Tech Co., Ltd. | Pharmaceutical compositions comprising a pyridyl cyanoguanidine and cyclodextrin and/or derivatives thereof |
| US8912184B1 (en) | 2010-03-01 | 2014-12-16 | Alzheimer's Institute Of America, Inc. | Therapeutic and diagnostic methods |
| AR082886A1 (es) | 2010-09-03 | 2013-01-16 | Forma Therapeutics Inc | Compuestos y composiciones farmaceuticas que los contienen |
| JP2013540781A (ja) | 2010-10-26 | 2013-11-07 | ティエンジン ホーメイ バイオ−テック カンパニー， リミテッド | Ｎ−（６−（４−クロロフェノキシ）ヘキシル）−ｎ’−シアノ−ｎ’’−（４−ピリジル）グアニジンの結晶多形とその製造及び使用 |
| CA3039589A1 (en) | 2016-10-18 | 2018-04-26 | Seattle Genetics, Inc. | Targeted delivery of nicotinamide adenine dinucleotide salvage pathway inhibitors |
| CA3060206A1 (en) | 2017-04-27 | 2018-11-01 | Seattle Genetics, Inc. | Quaternized nicotinamide adenine dinucleotide salvage pathway inhibitor conjugates |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994004499A1 (en) * | 1992-08-13 | 1994-03-03 | The Upjohn Company | Cyanoguanidines as potassium channel blockers |
| GB9219472D0 (en) * | 1992-09-15 | 1992-10-28 | Leo Pharm Prod Ltd | Chemical compounds |
| MX9603051A (es) * | 1994-01-28 | 1997-06-28 | Upjohn Co | Cianoguanidinas como bloqueadores del canal-k. |
-
1997
- 1997-05-29 GB GBGB9711125.6A patent/GB9711125D0/en active Pending
-
1998
- 1998-05-15 AT AT98924055T patent/ATE249438T1/de not_active IP Right Cessation
- 1998-05-15 RU RU99128082/04A patent/RU2195453C2/ru active
- 1998-05-15 AU AU76386/98A patent/AU733142B2/en not_active Expired
- 1998-05-15 ES ES98924055T patent/ES2206932T3/es not_active Expired - Lifetime
- 1998-05-15 JP JP50011499A patent/JP4408455B2/ja not_active Expired - Lifetime
- 1998-05-15 CA CA002292895A patent/CA2292895C/en not_active Expired - Lifetime
- 1998-05-15 CZ CZ19994234A patent/CZ294842B6/cs not_active IP Right Cessation
- 1998-05-15 HU HU0002921A patent/HUP0002921A3/hu unknown
- 1998-05-15 WO PCT/DK1998/000196 patent/WO1998054144A1/en not_active Ceased
- 1998-05-15 US US09/424,632 patent/US6346541B1/en not_active Expired - Lifetime
- 1998-05-15 DE DE69818041T patent/DE69818041T2/de not_active Expired - Lifetime
- 1998-05-15 DK DK98924055T patent/DK0984938T3/da active
- 1998-05-15 CN CN98805595A patent/CN1116283C/zh not_active Expired - Lifetime
- 1998-05-15 PL PL98337030A patent/PL190314B1/pl not_active IP Right Cessation
- 1998-05-15 EP EP98924055A patent/EP0984938B1/en not_active Expired - Lifetime
- 1998-05-15 PT PT98924055T patent/PT984938E/pt unknown
- 1998-05-15 RO RO99-01251A patent/RO120541B1/ro unknown
- 1998-05-15 KR KR10-1999-7011131A patent/KR100496220B1/ko not_active Expired - Lifetime
- 1998-05-15 NZ NZ501071A patent/NZ501071A/en not_active IP Right Cessation