JP2001524308A5 - - Google Patents
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- Publication number
- JP2001524308A5 JP2001524308A5 JP2000522220A JP2000522220A JP2001524308A5 JP 2001524308 A5 JP2001524308 A5 JP 2001524308A5 JP 2000522220 A JP2000522220 A JP 2000522220A JP 2000522220 A JP2000522220 A JP 2000522220A JP 2001524308 A5 JP2001524308 A5 JP 2001524308A5
- Authority
- JP
- Japan
- Prior art keywords
- nucleotide sequence
- polynucleotide
- amino acid
- polypeptide
- acid sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002773 nucleotide Substances 0.000 description 34
- 125000003729 nucleotide group Chemical group 0.000 description 34
- 239000002157 polynucleotide Substances 0.000 description 30
- 102000040430 polynucleotide Human genes 0.000 description 30
- 108091033319 polynucleotide Proteins 0.000 description 30
- 229920001184 polypeptide Polymers 0.000 description 27
- 102000004196 processed proteins & peptides Human genes 0.000 description 27
- 108090000765 processed proteins & peptides Proteins 0.000 description 27
- 125000003275 alpha amino acid group Chemical group 0.000 description 25
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 17
- 239000002299 complementary DNA Substances 0.000 description 14
- 239000013598 vector Substances 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 4
- 229930182817 methionine Natural products 0.000 description 3
- 125000001360 methionine group Chemical group N[C@@H](CCSC)C(=O)* 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 description 2
- 238000009396 hybridization Methods 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 description 1
- 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 238000012217 deletion Methods 0.000 description 1
- 230000037430 deletion Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 description 1
- 238000010188 recombinant method Methods 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6636997P | 1997-11-21 | 1997-11-21 | |
| US60/066,369 | 1997-11-21 | ||
| PCT/US1998/024619 WO1999027078A1 (en) | 1997-11-21 | 1998-11-18 | Chemokine alpha-5 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005334620A Division JP2006094863A (ja) | 1997-11-21 | 2005-11-18 | ケモカインα−５ |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001524308A JP2001524308A (ja) | 2001-12-04 |
| JP2001524308A5 true JP2001524308A5 (https=) | 2006-01-19 |
Family
ID=22069070
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000522220A Pending JP2001524308A (ja) | 1997-11-21 | 1998-11-18 | ケモカインα−５ |
| JP2005334620A Pending JP2006094863A (ja) | 1997-11-21 | 2005-11-18 | ケモカインα−５ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2005334620A Pending JP2006094863A (ja) | 1997-11-21 | 2005-11-18 | ケモカインα−５ |
Country Status (8)
| Country | Link |
|---|---|
| US (4) | US6395514B1 (https=) |
| EP (1) | EP1036164B1 (https=) |
| JP (2) | JP2001524308A (https=) |
| AT (1) | ATE472599T1 (https=) |
| AU (1) | AU1417999A (https=) |
| CA (1) | CA2310892A1 (https=) |
| DE (1) | DE69841751D1 (https=) |
| WO (1) | WO1999027078A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE472599T1 (de) * | 1997-11-21 | 2010-07-15 | Human Genome Sciences Inc | Chemokin alpha-5 |
| IL128252A0 (en) * | 1999-01-27 | 1999-11-30 | Compugen Ltd | Novel nucleic acid and amino acid sequences |
| US6319675B1 (en) | 1999-11-24 | 2001-11-20 | Millennium Pharmaceuticals, Inc. | Methods for detecting and/or identifying agents which bind and/or modulate function of “bonzo” chemokine receptor |
| US7208152B2 (en) | 1999-11-24 | 2007-04-24 | Millennium Pharmaceuticals, Inc. | Antibodies for “Bonzo” chemokine receptor and therapeutic uses thereof |
| DK3248613T3 (da) | 2005-07-18 | 2022-03-14 | Seagen Inc | Beta-glucuronid-lægemiddel-linkerkonjugater |
| PT2099823E (pt) | 2006-12-01 | 2014-12-22 | Seattle Genetics Inc | Agentes de ligação ao alvo variantes e suas utilizações |
| UA112062C2 (uk) | 2010-10-04 | 2016-07-25 | Бьорінгер Інгельхайм Інтернаціональ Гмбх | Cd33-зв'язувальний агент |
| CN109843919A (zh) | 2016-03-25 | 2019-06-04 | 西雅图基因公司 | 用于制备聚乙二醇化的药物-接头及其中间体的方法 |
| KR102648564B1 (ko) | 2017-03-24 | 2024-03-19 | 씨젠 인크. | 글루쿠로니드 약물-링커의 제조 공정 및 그 중간물 |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3773919A (en) * | 1969-10-23 | 1973-11-20 | Du Pont | Polylactide-drug mixtures |
| US4433092A (en) | 1981-03-09 | 1984-02-21 | Champion Spark Plug Company | Green ceramic of lead-free glass, conductive carbon, silicone resin and AlPO4, useful, after firing, as an electrical resistor |
| US4485045A (en) * | 1981-07-06 | 1984-11-27 | Research Corporation | Synthetic phosphatidyl cholines useful in forming liposomes |
| DE3374837D1 (en) * | 1982-02-17 | 1988-01-21 | Ciba Geigy Ag | Lipids in the aqueous phase |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US4544545A (en) * | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
| DE3586772T2 (de) * | 1984-07-24 | 1993-03-04 | Coselco Mimotopes Pty Ltd | Verfahren zur bestimmung von mimotopen. |
| EP0173494A3 (en) | 1984-08-27 | 1987-11-25 | The Board Of Trustees Of The Leland Stanford Junior University | Chimeric receptors by dna splicing and expression |
| GB8422238D0 (en) | 1984-09-03 | 1984-10-10 | Neuberger M S | Chimeric proteins |
| US4631211A (en) | 1985-03-25 | 1986-12-23 | Scripps Clinic & Research Foundation | Means for sequential solid phase organic synthesis and methods using the same |
| DE3689123T2 (de) | 1985-11-01 | 1994-03-03 | Xoma Corp | Modulare einheit von antikörpergenen, daraus hergestellte antikörper und verwendung. |
| EP0394827A1 (en) | 1989-04-26 | 1990-10-31 | F. Hoffmann-La Roche Ag | Chimaeric CD4-immunoglobulin polypeptides |
| US5480971A (en) | 1993-06-17 | 1996-01-02 | Houghten Pharmaceuticals, Inc. | Peralkylated oligopeptide mixtures |
| ATE472599T1 (de) | 1997-11-21 | 2010-07-15 | Human Genome Sciences Inc | Chemokin alpha-5 |
| EP1080194A2 (en) | 1998-05-29 | 2001-03-07 | Incyte Pharmaceuticals, Inc. | Human transmembrane proteins |
| AU3263101A (en) | 1999-11-24 | 2001-06-04 | Millennium Pharmaceuticals, Inc. | Expression cloning method |
| US6319675B1 (en) | 1999-11-24 | 2001-11-20 | Millennium Pharmaceuticals, Inc. | Methods for detecting and/or identifying agents which bind and/or modulate function of “bonzo” chemokine receptor |
| US7208152B2 (en) | 1999-11-24 | 2007-04-24 | Millennium Pharmaceuticals, Inc. | Antibodies for “Bonzo” chemokine receptor and therapeutic uses thereof |
| WO2004045526A2 (en) | 2002-11-15 | 2004-06-03 | Morehouse School Of Medicine | Anti-chemokine and associated receptors antibodies for inhibition of growth of neoplasms |
-
1998
- 1998-11-18 AT AT98958066T patent/ATE472599T1/de not_active IP Right Cessation
- 1998-11-18 AU AU14179/99A patent/AU1417999A/en not_active Abandoned
- 1998-11-18 JP JP2000522220A patent/JP2001524308A/ja active Pending
- 1998-11-18 EP EP98958066A patent/EP1036164B1/en not_active Expired - Lifetime
- 1998-11-18 DE DE69841751T patent/DE69841751D1/de not_active Expired - Lifetime
- 1998-11-18 CA CA002310892A patent/CA2310892A1/en not_active Abandoned
- 1998-11-18 WO PCT/US1998/024619 patent/WO1999027078A1/en not_active Ceased
- 1998-11-18 US US09/195,106 patent/US6395514B1/en not_active Expired - Lifetime
-
2002
- 2002-04-03 US US10/114,482 patent/US7060261B2/en not_active Expired - Fee Related
-
2005
- 2005-09-13 US US11/224,076 patent/US7320869B2/en not_active Expired - Fee Related
- 2005-11-18 JP JP2005334620A patent/JP2006094863A/ja active Pending
-
2008
- 2008-01-22 US US12/010,210 patent/US20080317756A1/en not_active Abandoned
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