JP2002516103A5 - - Google Patents

Info

Publication number

JP2002516103A5

JP2002516103A5 JP2000551001A JP2000551001A JP2002516103A5 JP 2002516103 A5 JP2002516103 A5 JP 2002516103A5 JP 2000551001 A JP2000551001 A JP 2000551001A JP 2000551001 A JP2000551001 A JP 2000551001A JP 2002516103 A5 JP2002516103 A5 JP 2002516103A5

Authority

JP

Japan

Prior art keywords

seq

polypeptide

polynucleotide

sequence

nucleic acid

Prior art date

1999-05-27

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Withdrawn

Links

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• 108091033319 polynucleotide Proteins 0.000 description 80
• 102000040430 polynucleotide Human genes 0.000 description 80
• 239000002157 polynucleotide Substances 0.000 description 80
• 229920001184 polypeptide Polymers 0.000 description 79
• 108090000765 processed proteins & peptides Proteins 0.000 description 79
• 102000004196 processed proteins & peptides Human genes 0.000 description 79
• 102000039446 nucleic acids Human genes 0.000 description 33
• 108020004707 nucleic acids Proteins 0.000 description 33
• 150000007523 nucleic acids Chemical class 0.000 description 33
• 210000004027 cell Anatomy 0.000 description 30
• 239000012634 fragment Substances 0.000 description 26
• 239000002299 complementary DNA Substances 0.000 description 25
• 238000000034 method Methods 0.000 description 25
• 239000002773 nucleotide Substances 0.000 description 25
• 125000003729 nucleotide group Chemical group 0.000 description 25
• 108090000623 proteins and genes Proteins 0.000 description 18
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 description 16
• 102000004169 proteins and genes Human genes 0.000 description 15
• 230000000694 effects Effects 0.000 description 12
• 125000003275 alpha amino acid group Chemical group 0.000 description 11
• 108091026890 Coding region Proteins 0.000 description 10
• 230000001575 pathological effect Effects 0.000 description 8
• 238000004166 bioassay Methods 0.000 description 6
• 238000004519 manufacturing process Methods 0.000 description 6
• 241000894007 species Species 0.000 description 6
• 239000006228 supernatant Substances 0.000 description 6
• 150000001413 amino acids Chemical class 0.000 description 5
• 239000012472 biological sample Substances 0.000 description 4
• 238000012258 culturing Methods 0.000 description 4
• 230000004071 biological effect Effects 0.000 description 3
• 230000000295 complement effect Effects 0.000 description 3
• 230000037430 deletion Effects 0.000 description 3
• 238000012217 deletion Methods 0.000 description 3
• 239000000047 product Substances 0.000 description 3
• 241000588724 Escherichia coli Species 0.000 description 2
• 108010076504 Protein Sorting Signals Proteins 0.000 description 2
• 230000035772 mutation Effects 0.000 description 2
• 108020004414 DNA Proteins 0.000 description 1
• 241000238631 Hexapoda Species 0.000 description 1
• 102000001706 Immunoglobulin Fab Fragments Human genes 0.000 description 1
• 108010054477 Immunoglobulin Fab Fragments Proteins 0.000 description 1
• 239000002202 Polyethylene glycol Substances 0.000 description 1
• 230000001580 bacterial effect Effects 0.000 description 1
• 210000003527 eukaryotic cell Anatomy 0.000 description 1
• 230000002538 fungal effect Effects 0.000 description 1
• 229920001223 polyethylene glycol Polymers 0.000 description 1
• 210000001236 prokaryotic cell Anatomy 0.000 description 1
• 210000005253 yeast cell Anatomy 0.000 description 1