JP2001522888A5 - - Google Patents
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- Publication number
- JP2001522888A5 JP2001522888A5 JP2000520782A JP2000520782A JP2001522888A5 JP 2001522888 A5 JP2001522888 A5 JP 2001522888A5 JP 2000520782 A JP2000520782 A JP 2000520782A JP 2000520782 A JP2000520782 A JP 2000520782A JP 2001522888 A5 JP2001522888 A5 JP 2001522888A5
- Authority
- JP
- Japan
- Prior art keywords
- anesthetic
- solution according
- saccharide
- solution
- saccharides
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000000243 solution Substances 0.000 description 11
- 150000001720 carbohydrates Chemical class 0.000 description 9
- 230000003444 anaesthetic effect Effects 0.000 description 8
- 210000001175 cerebrospinal fluid Anatomy 0.000 description 3
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000005484 gravity Effects 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 150000003839 salts Chemical class 0.000 description 2
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 125000000217 alkyl group Chemical group 0.000 description 1
- 229960003150 bupivacaine Drugs 0.000 description 1
- 125000004432 carbon atom Chemical group C* 0.000 description 1
- 150000001767 cationic compounds Chemical class 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 125000002791 glucosyl group Chemical group C1([C@H](O)[C@@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
- 229910001411 inorganic cation Inorganic materials 0.000 description 1
- LEBVLXFERQHONN-INIZCTEOSA-N levobupivacaine Chemical compound CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-INIZCTEOSA-N 0.000 description 1
- 229960004288 levobupivacaine Drugs 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000008174 sterile solution Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB9724506.2 | 1997-11-19 | ||
| GBGB9724506.2A GB9724506D0 (en) | 1997-11-19 | 1997-11-19 | Levobupivacaine and its use |
| GB9818109.2 | 1998-08-19 | ||
| GBGB9818109.2A GB9818109D0 (en) | 1998-08-19 | 1998-08-19 | Anaesthetic Formulation |
| PCT/GB1998/003479 WO1999025349A1 (en) | 1997-11-19 | 1998-11-19 | Anaesthetic formulation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001522888A JP2001522888A (ja) | 2001-11-20 |
| JP2001522888A5 true JP2001522888A5 (enExample) | 2006-01-19 |
Family
ID=26312628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000520782A Pending JP2001522888A (ja) | 1997-11-19 | 1998-11-19 | 麻酔用製剤 |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5932597A (enExample) |
| EP (1) | EP1032390B1 (enExample) |
| JP (1) | JP2001522888A (enExample) |
| KR (1) | KR100695588B1 (enExample) |
| CN (1) | CN1131033C (enExample) |
| AT (1) | ATE253913T1 (enExample) |
| AU (1) | AU740914B2 (enExample) |
| BR (1) | BR9814883A (enExample) |
| CA (1) | CA2308495C (enExample) |
| DE (1) | DE69819770T2 (enExample) |
| DK (1) | DK1032390T3 (enExample) |
| ES (1) | ES2209217T3 (enExample) |
| HU (1) | HU228143B1 (enExample) |
| IL (1) | IL135922A0 (enExample) |
| NO (1) | NO328684B1 (enExample) |
| PT (1) | PT1032390E (enExample) |
| WO (1) | WO1999025349A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824161D0 (en) * | 1998-11-04 | 1998-12-30 | Darwin Discovery Ltd | Drug formulation |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| SI1575569T1 (sl) | 2002-12-13 | 2010-12-31 | Durect Corp | Oralni sistem dostave zdravila, ki obsega visokoviskozne tekoče nosilne materiale |
| SI2767292T1 (sl) | 2004-09-17 | 2017-01-31 | Durect Corporation | Pripravek, ki vsebuje lokalni anestetik SAIB, s podaljšanim sproščanjem |
| US20060270708A1 (en) * | 2005-05-25 | 2006-11-30 | Navinta Llc | Novel process for preparation of isotonic aqueous injection of ropivacaine |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP2117521B1 (en) | 2006-11-03 | 2012-06-27 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| EP2067471B1 (en) * | 2007-12-06 | 2018-02-14 | Durect Corporation | Oral pharmaceutical dosage forms |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| SG11201407323WA (en) * | 2012-05-10 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of local pain |
| CA2905131A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| EP3331508B1 (en) * | 2015-07-13 | 2024-08-14 | Neon Laboratories Ltd. | Hyperbaric solution injection of levobupivacaine hydrochloride comprising levobupivacaine hydrochloride |
| JP7258561B2 (ja) | 2016-07-06 | 2023-04-17 | オリエント ファーマ シーオー．，エルティーディー． | 薬物組成物、バリヤー層及び薬物層を有している経口投与形態 |
| KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
| KR20230145053A (ko) | 2021-01-12 | 2023-10-17 | 듀렉트 코퍼레이션 | 지속 방출 약물 전달 시스템 및 관련 방법 |
| WO2025175174A1 (en) * | 2024-02-14 | 2025-08-21 | The Children's Medical Center Corporation | 2'-6'-pipecoloxylidide as a sensory-selective anesthetic |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8802564D0 (sv) * | 1988-07-08 | 1988-07-08 | Astra Ab | New synergistic preparations and a new method of alleviation of pain |
| GB9321061D0 (en) * | 1993-10-13 | 1993-12-01 | Chiroscience Ltd | Analgestic agent and its use |
| EP0727210B1 (en) * | 1993-10-13 | 2001-12-19 | Darwin Discovery Limited | Analgesic agent and its use |
-
1998
- 1998-11-19 WO PCT/GB1998/003479 patent/WO1999025349A1/en not_active Ceased
- 1998-11-19 DE DE69819770T patent/DE69819770T2/de not_active Expired - Lifetime
- 1998-11-19 JP JP2000520782A patent/JP2001522888A/ja active Pending
- 1998-11-19 ES ES98954639T patent/ES2209217T3/es not_active Expired - Lifetime
- 1998-11-19 HU HU0004665A patent/HU228143B1/hu unknown
- 1998-11-19 DK DK98954639T patent/DK1032390T3/da active
- 1998-11-19 CN CN98811339A patent/CN1131033C/zh not_active Expired - Lifetime
- 1998-11-19 KR KR1020007005443A patent/KR100695588B1/ko not_active Expired - Lifetime
- 1998-11-19 US US09/195,908 patent/US5932597A/en not_active Expired - Lifetime
- 1998-11-19 AT AT98954639T patent/ATE253913T1/de active
- 1998-11-19 PT PT98954639T patent/PT1032390E/pt unknown
- 1998-11-19 EP EP98954639A patent/EP1032390B1/en not_active Expired - Lifetime
- 1998-11-19 IL IL13592298A patent/IL135922A0/xx not_active IP Right Cessation
- 1998-11-19 BR BR9814883-4A patent/BR9814883A/pt not_active Application Discontinuation
- 1998-11-19 AU AU11684/99A patent/AU740914B2/en not_active Expired
- 1998-11-19 CA CA002308495A patent/CA2308495C/en not_active Expired - Lifetime
-
2000
- 2000-05-18 NO NO20002545A patent/NO328684B1/no not_active IP Right Cessation
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