KR100695588B1 - 마취용 제형물 - Google Patents

마취용 제형물 Download PDF

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Publication number
KR100695588B1
KR100695588B1 KR1020007005443A KR20007005443A KR100695588B1 KR 100695588 B1 KR100695588 B1 KR 100695588B1 KR 1020007005443 A KR1020007005443 A KR 1020007005443A KR 20007005443 A KR20007005443 A KR 20007005443A KR 100695588 B1 KR100695588 B1 KR 100695588B1
Authority
KR
South Korea
Prior art keywords
aqueous solution
anesthetic
bupivacaine
amount
glucose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
KR1020007005443A
Other languages
English (en)
Korean (ko)
Other versions
KR20010032241A (ko
Inventor
스테펜 브라운
Original Assignee
다윈 디스커버리 리미티드
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9724506.2A external-priority patent/GB9724506D0/en
Priority claimed from GBGB9818109.2A external-priority patent/GB9818109D0/en
Application filed by 다윈 디스커버리 리미티드 filed Critical 다윈 디스커버리 리미티드
Publication of KR20010032241A publication Critical patent/KR20010032241A/ko
Application granted granted Critical
Publication of KR100695588B1 publication Critical patent/KR100695588B1/ko
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A61P23/02—Local anaesthetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Biochemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
KR1020007005443A 1997-11-19 1998-11-19 마취용 제형물 Expired - Lifetime KR100695588B1 (ko)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB9724506.2 1997-11-19
GBGB9724506.2A GB9724506D0 (en) 1997-11-19 1997-11-19 Levobupivacaine and its use
GBGB9818109.2A GB9818109D0 (en) 1998-08-19 1998-08-19 Anaesthetic Formulation
GB9818109.2 1998-08-19
PCT/GB1998/003479 WO1999025349A1 (en) 1997-11-19 1998-11-19 Anaesthetic formulation

Publications (2)

Publication Number Publication Date
KR20010032241A KR20010032241A (ko) 2001-04-16
KR100695588B1 true KR100695588B1 (ko) 2007-03-14

Family

ID=26312628

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007005443A Expired - Lifetime KR100695588B1 (ko) 1997-11-19 1998-11-19 마취용 제형물

Country Status (17)

Country Link
US (1) US5932597A (enExample)
EP (1) EP1032390B1 (enExample)
JP (1) JP2001522888A (enExample)
KR (1) KR100695588B1 (enExample)
CN (1) CN1131033C (enExample)
AT (1) ATE253913T1 (enExample)
AU (1) AU740914B2 (enExample)
BR (1) BR9814883A (enExample)
CA (1) CA2308495C (enExample)
DE (1) DE69819770T2 (enExample)
DK (1) DK1032390T3 (enExample)
ES (1) ES2209217T3 (enExample)
HU (1) HU228143B1 (enExample)
IL (1) IL135922A0 (enExample)
NO (1) NO328684B1 (enExample)
PT (1) PT1032390E (enExample)
WO (1) WO1999025349A1 (enExample)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9824161D0 (en) * 1998-11-04 1998-12-30 Darwin Discovery Ltd Drug formulation
US20040001889A1 (en) 2002-06-25 2004-01-01 Guohua Chen Short duration depot formulations
EP2959893A1 (en) 2002-12-13 2015-12-30 DURECT Corporation Oral drug delivery system comprising high viscosity liquid carrier materials
CA2581287C (en) * 2004-09-17 2015-08-25 Durect Corporation Sustained local anesthetic composition containing bupivacaine and saib
US20060270708A1 (en) * 2005-05-25 2006-11-30 Navinta Llc Novel process for preparation of isotonic aqueous injection of ropivacaine
US20070027105A1 (en) 2005-07-26 2007-02-01 Alza Corporation Peroxide removal from drug delivery vehicle
EP2117521B1 (en) 2006-11-03 2012-06-27 Durect Corporation Transdermal delivery systems comprising bupivacaine
WO2009088414A2 (en) 2007-12-06 2009-07-16 Durect Corporation Oral pharmaceutical dosage forms
US20100260844A1 (en) 2008-11-03 2010-10-14 Scicinski Jan J Oral pharmaceutical dosage forms
SG11201407323WA (en) * 2012-05-10 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of local pain
CA2905131A1 (en) 2013-03-15 2014-09-18 Durect Corporation Compositions with a rheological modifier to reduce dissolution variability
PT3331508T (pt) * 2015-07-13 2024-12-19 Neon Laboratories Ltd Solução de injeção hiperbárica de cloridrato de levobupivacaína compreendendo cloridrato de levobupivacaína
KR102413459B1 (ko) 2016-07-06 2022-06-24 듀렉트 코퍼레이션 약물 조성물, 장벽 층 및 약물 층을 갖는 경구 투여 형태
KR20220140711A (ko) 2020-01-13 2022-10-18 듀렉트 코퍼레이션 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법
EP4277702A1 (en) 2021-01-12 2023-11-22 Durect Corporation Sustained release drug delivery systems and related methods
WO2025175174A1 (en) * 2024-02-14 2025-08-21 The Children's Medical Center Corporation 2'-6'-pipecoloxylidide as a sensory-selective anesthetic

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000390A1 (en) * 1988-07-08 1990-01-25 Aktiebolaget Astra New synergistic preparations containing dezocine and a local anaesthetic and a new method of alleviation of pain

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9321061D0 (en) * 1993-10-13 1993-12-01 Chiroscience Ltd Analgestic agent and its use
ES2170179T3 (es) * 1993-10-13 2002-08-01 Darwin Discovery Ltd Agente analgesico y su utilizacion.

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000390A1 (en) * 1988-07-08 1990-01-25 Aktiebolaget Astra New synergistic preparations containing dezocine and a local anaesthetic and a new method of alleviation of pain

Also Published As

Publication number Publication date
NO20002545D0 (no) 2000-05-18
PT1032390E (pt) 2004-04-30
US5932597A (en) 1999-08-03
NO328684B1 (no) 2010-04-26
HUP0004665A2 (hu) 2001-04-28
CN1279607A (zh) 2001-01-10
KR20010032241A (ko) 2001-04-16
JP2001522888A (ja) 2001-11-20
AU1168499A (en) 1999-06-07
CN1131033C (zh) 2003-12-17
DE69819770T2 (de) 2004-09-23
HU228143B1 (en) 2012-12-28
CA2308495C (en) 2009-01-06
EP1032390B1 (en) 2003-11-12
EP1032390A1 (en) 2000-09-06
HUP0004665A3 (en) 2004-05-28
HK1026848A1 (en) 2000-12-29
DE69819770D1 (de) 2003-12-18
DK1032390T3 (da) 2004-03-15
AU740914B2 (en) 2001-11-15
BR9814883A (pt) 2000-10-03
CA2308495A1 (en) 1999-05-27
IL135922A0 (en) 2001-05-20
WO1999025349A1 (en) 1999-05-27
ATE253913T1 (de) 2003-11-15
NO20002545L (no) 2000-05-18
ES2209217T3 (es) 2004-06-16

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