DK1032390T3 - Anæstetisk formulering - Google Patents
Anæstetisk formuleringInfo
- Publication number
- DK1032390T3 DK1032390T3 DK98954639T DK98954639T DK1032390T3 DK 1032390 T3 DK1032390 T3 DK 1032390T3 DK 98954639 T DK98954639 T DK 98954639T DK 98954639 T DK98954639 T DK 98954639T DK 1032390 T3 DK1032390 T3 DK 1032390T3
- Authority
- DK
- Denmark
- Prior art keywords
- saccharide
- amount
- additional non
- anesthetic agent
- anesthetic formulation
- Prior art date
Links
- 230000003444 anaesthetic effect Effects 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 abstract 4
- 210000001175 cerebrospinal fluid Anatomy 0.000 abstract 2
- 239000003193 general anesthetic agent Substances 0.000 abstract 2
- LEBVLXFERQHONN-UHFFFAOYSA-N 1-butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide Chemical compound CCCCN1CCCCC1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 229960003150 bupivacaine Drugs 0.000 abstract 1
- LEBVLXFERQHONN-INIZCTEOSA-N levobupivacaine Chemical compound CCCCN1CCCC[C@H]1C(=O)NC1=C(C)C=CC=C1C LEBVLXFERQHONN-INIZCTEOSA-N 0.000 abstract 1
- 229960004288 levobupivacaine Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
- A61P23/02—Local anaesthetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Anesthesiology (AREA)
- Molecular Biology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9724506.2A GB9724506D0 (en) | 1997-11-19 | 1997-11-19 | Levobupivacaine and its use |
| GBGB9818109.2A GB9818109D0 (en) | 1998-08-19 | 1998-08-19 | Anaesthetic Formulation |
| PCT/GB1998/003479 WO1999025349A1 (en) | 1997-11-19 | 1998-11-19 | Anaesthetic formulation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1032390T3 true DK1032390T3 (da) | 2004-03-15 |
Family
ID=26312628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98954639T DK1032390T3 (da) | 1997-11-19 | 1998-11-19 | Anæstetisk formulering |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US5932597A (enExample) |
| EP (1) | EP1032390B1 (enExample) |
| JP (1) | JP2001522888A (enExample) |
| KR (1) | KR100695588B1 (enExample) |
| CN (1) | CN1131033C (enExample) |
| AT (1) | ATE253913T1 (enExample) |
| AU (1) | AU740914B2 (enExample) |
| BR (1) | BR9814883A (enExample) |
| CA (1) | CA2308495C (enExample) |
| DE (1) | DE69819770T2 (enExample) |
| DK (1) | DK1032390T3 (enExample) |
| ES (1) | ES2209217T3 (enExample) |
| HU (1) | HU228143B1 (enExample) |
| IL (1) | IL135922A0 (enExample) |
| NO (1) | NO328684B1 (enExample) |
| PT (1) | PT1032390E (enExample) |
| WO (1) | WO1999025349A1 (enExample) |
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9824161D0 (en) * | 1998-11-04 | 1998-12-30 | Darwin Discovery Ltd | Drug formulation |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| EP2959893A1 (en) | 2002-12-13 | 2015-12-30 | DURECT Corporation | Oral drug delivery system comprising high viscosity liquid carrier materials |
| CA2581287C (en) * | 2004-09-17 | 2015-08-25 | Durect Corporation | Sustained local anesthetic composition containing bupivacaine and saib |
| US20060270708A1 (en) * | 2005-05-25 | 2006-11-30 | Navinta Llc | Novel process for preparation of isotonic aqueous injection of ropivacaine |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| EP2117521B1 (en) | 2006-11-03 | 2012-06-27 | Durect Corporation | Transdermal delivery systems comprising bupivacaine |
| WO2009088414A2 (en) | 2007-12-06 | 2009-07-16 | Durect Corporation | Oral pharmaceutical dosage forms |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| SG11201407323WA (en) * | 2012-05-10 | 2014-12-30 | Cellix Bio Private Ltd | Compositions and methods for the treatment of local pain |
| CA2905131A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| PT3331508T (pt) * | 2015-07-13 | 2024-12-19 | Neon Laboratories Ltd | Solução de injeção hiperbárica de cloridrato de levobupivacaína compreendendo cloridrato de levobupivacaína |
| KR102413459B1 (ko) | 2016-07-06 | 2022-06-24 | 듀렉트 코퍼레이션 | 약물 조성물, 장벽 층 및 약물 층을 갖는 경구 투여 형태 |
| KR20220140711A (ko) | 2020-01-13 | 2022-10-18 | 듀렉트 코퍼레이션 | 불순물이 감소된 지속 방출 약물 전달 시스템 및 관련 방법 |
| EP4277702A1 (en) | 2021-01-12 | 2023-11-22 | Durect Corporation | Sustained release drug delivery systems and related methods |
| WO2025175174A1 (en) * | 2024-02-14 | 2025-08-21 | The Children's Medical Center Corporation | 2'-6'-pipecoloxylidide as a sensory-selective anesthetic |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8802564D0 (sv) * | 1988-07-08 | 1988-07-08 | Astra Ab | New synergistic preparations and a new method of alleviation of pain |
| GB9321061D0 (en) * | 1993-10-13 | 1993-12-01 | Chiroscience Ltd | Analgestic agent and its use |
| ES2170179T3 (es) * | 1993-10-13 | 2002-08-01 | Darwin Discovery Ltd | Agente analgesico y su utilizacion. |
-
1998
- 1998-11-19 CN CN98811339A patent/CN1131033C/zh not_active Expired - Lifetime
- 1998-11-19 PT PT98954639T patent/PT1032390E/pt unknown
- 1998-11-19 AT AT98954639T patent/ATE253913T1/de active
- 1998-11-19 CA CA002308495A patent/CA2308495C/en not_active Expired - Lifetime
- 1998-11-19 AU AU11684/99A patent/AU740914B2/en not_active Expired
- 1998-11-19 KR KR1020007005443A patent/KR100695588B1/ko not_active Expired - Lifetime
- 1998-11-19 DE DE69819770T patent/DE69819770T2/de not_active Expired - Lifetime
- 1998-11-19 BR BR9814883-4A patent/BR9814883A/pt not_active Application Discontinuation
- 1998-11-19 US US09/195,908 patent/US5932597A/en not_active Expired - Lifetime
- 1998-11-19 EP EP98954639A patent/EP1032390B1/en not_active Expired - Lifetime
- 1998-11-19 WO PCT/GB1998/003479 patent/WO1999025349A1/en not_active Ceased
- 1998-11-19 DK DK98954639T patent/DK1032390T3/da active
- 1998-11-19 IL IL13592298A patent/IL135922A0/xx not_active IP Right Cessation
- 1998-11-19 JP JP2000520782A patent/JP2001522888A/ja active Pending
- 1998-11-19 HU HU0004665A patent/HU228143B1/hu unknown
- 1998-11-19 ES ES98954639T patent/ES2209217T3/es not_active Expired - Lifetime
-
2000
- 2000-05-18 NO NO20002545A patent/NO328684B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| NO20002545D0 (no) | 2000-05-18 |
| PT1032390E (pt) | 2004-04-30 |
| US5932597A (en) | 1999-08-03 |
| KR100695588B1 (ko) | 2007-03-14 |
| NO328684B1 (no) | 2010-04-26 |
| HUP0004665A2 (hu) | 2001-04-28 |
| CN1279607A (zh) | 2001-01-10 |
| KR20010032241A (ko) | 2001-04-16 |
| JP2001522888A (ja) | 2001-11-20 |
| AU1168499A (en) | 1999-06-07 |
| CN1131033C (zh) | 2003-12-17 |
| DE69819770T2 (de) | 2004-09-23 |
| HU228143B1 (en) | 2012-12-28 |
| CA2308495C (en) | 2009-01-06 |
| EP1032390B1 (en) | 2003-11-12 |
| EP1032390A1 (en) | 2000-09-06 |
| HUP0004665A3 (en) | 2004-05-28 |
| HK1026848A1 (en) | 2000-12-29 |
| DE69819770D1 (de) | 2003-12-18 |
| AU740914B2 (en) | 2001-11-15 |
| BR9814883A (pt) | 2000-10-03 |
| CA2308495A1 (en) | 1999-05-27 |
| IL135922A0 (en) | 2001-05-20 |
| WO1999025349A1 (en) | 1999-05-27 |
| ATE253913T1 (de) | 2003-11-15 |
| NO20002545L (no) | 2000-05-18 |
| ES2209217T3 (es) | 2004-06-16 |
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