|
US7232899B2
(en)
|
1996-09-25 |
2007-06-19 |
The Scripps Research Institute |
Adenovirus vectors, packaging cell lines, compositions, and methods for preparation and use
|
|
AU4070499A
(en)
|
1998-04-30 |
1999-11-16 |
Cornell Research Foundation Inc. |
Adenoviral vectors with tandem fiber proteins
|
|
AU767975B2
(en)
*
|
1998-09-11 |
2003-11-27 |
Genvec, Inc. |
Alternatively targeted adenovirus
|
|
EP1020529B1
(en)
*
|
1998-11-20 |
2005-06-01 |
Crucell Holland B.V. |
Gene delivery vectors provided with a tissue tropism for smooth muscle cells, and/or endothelial cells
|
|
IL133032A
(en)
*
|
1998-11-20 |
2007-06-03 |
Introgene Bv |
Adenoviral gene delivery vectors provided with a tissue tropism for smooth muscle cells and /or endothelial cells
|
|
JP2000279178A
(ja)
*
|
1999-02-24 |
2000-10-10 |
Japan Found Cancer Res |
ウイルスベクター
|
|
DE19932688B4
(de)
|
1999-07-13 |
2009-10-08 |
Scil Proteins Gmbh |
Design von Beta-Faltblatt-Proteinen des gamma-II-kristallins antikörperähnlichen
|
|
CA2392272A1
(fr)
*
|
1999-11-25 |
2001-05-31 |
Transgene S.A. |
Fibre adenovirable modifiee et utilisations
|
|
JP2003534805A
(ja)
*
|
2000-05-31 |
2003-11-25 |
ユニバーシティ オブ サスカチュワン |
変化した親和性を有する改変ウシアデノウイルス
|
|
JP2004512015A
(ja)
*
|
2000-06-02 |
2004-04-22 |
ノバルティス アクチエンゲゼルシャフト |
変異ファイバー蛋白質を有するアデノウィルス粒子
|
|
WO2004007537A2
(en)
*
|
2002-07-10 |
2004-01-22 |
Transgene S.A. |
Modified adenoviral fiber with ablated to cellular receptors
|
|
US20060281090A1
(en)
*
|
2003-05-01 |
2006-12-14 |
University Of Washington Uw Tech Transfer- Invention Licensing |
Capsid-modified adenovirus vectors and methods of using the same
|
|
CA2524499A1
(en)
*
|
2003-05-14 |
2004-11-25 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti Spa |
Broadening adenovirus tropism
|
|
DE10324447A1
(de)
|
2003-05-28 |
2004-12-30 |
Scil Proteins Gmbh |
Generierung künstlicher Bindungsproteine auf der Grundlage von Ubiquitin
|
|
GB0313132D0
(en)
*
|
2003-06-06 |
2003-07-09 |
Ich Productions Ltd |
Peptide ligands
|
|
US20070036721A1
(en)
*
|
2003-09-23 |
2007-02-15 |
Uab Resarch Foundation |
Methods and compositions for in vivo inflammation monitoring
|
|
JP4814800B2
(ja)
*
|
2004-01-23 |
2011-11-16 |
イステイチユート・デイ・リチエルケ・デイ・ビオロジア・モレコラーレ・ピ・アンジエレツテイ・エツセ・ピー・アー |
チンパンジーアデノウイルスワクチン担体
|
|
DE102004049479A1
(de)
|
2004-10-11 |
2006-04-13 |
Scil Proteins Gmbh |
Proteinkonjugate zur Verwendung in Therapie, Diagnose und Chromatographie
|
|
US20070010016A1
(en)
*
|
2005-03-11 |
2007-01-11 |
Mccelland Alan |
Gene transfer with adenoviruses having modified fiber proteins
|
|
CA2610919C
(en)
*
|
2005-06-17 |
2013-09-10 |
Istituto Di Ricerche Di Biologia Molecolare P. Angeletti S.P.A. |
Hepatitis c virus nucleic acid vaccine
|
|
WO2007094653A1
(en)
*
|
2006-02-13 |
2007-08-23 |
Vereniging Voor Christelijk Hoger Onderwijs, Wetenschappelijk Onderzoek En Patientenzorg |
Adenovirus particles having a chimeric adenovirus spike protein, use thereof and methods for producing such particles.
|
|
EP1925664A1
(en)
*
|
2006-11-15 |
2008-05-28 |
Scil proteins GmbH |
Artificial binding proteins based on a modified alpha helical region of ubiquitin
|
|
WO2009111738A2
(en)
|
2008-03-06 |
2009-09-11 |
Mayo Foundation For Medical Education And Research |
Single cycle replicating adenovirus vectors
|
|
BR112012014417B1
(pt)
|
2009-12-14 |
2021-11-09 |
Scil Proteins Gmbh |
Proteínas ubiquitinas modificadas tendo uma atividade de ligação específica para o extradomínio b de fibronectina
|
|
DK2721152T3
(da)
|
2011-06-15 |
2019-07-01 |
Navigo Proteins Gmbh |
Dimere bindingsproteiner baseret på modificerede ubiquitiner
|
|
SG11201507393TA
(en)
|
2013-03-14 |
2015-10-29 |
Salk Inst For Biological Studi |
Oncolytic adenovirus compositions
|
|
ES2899913T3
(es)
|
2014-09-24 |
2022-03-15 |
Salk Inst For Biological Studi |
Virus tumorales oncolíticos y métodos de uso
|
|
EP3253785B1
(en)
|
2015-02-06 |
2019-04-10 |
Navigo Proteins Gmbh |
Novel egfr binding proteins
|
|
DK3322721T3
(da)
|
2015-07-16 |
2022-03-14 |
Navigo Proteins Gmbh |
Nye immunglobulin-bindende proteiner og deres anvendelse i affinitetsoprensning
|
|
JP2018520675A
(ja)
|
2015-07-20 |
2018-08-02 |
ナフィゴ プロテインズ ゲゼルシャフト ミット ベシュレンクテル ハフツングＮａｖｉｇｏ Ｐｒｏｔｅｉｎｓ ＧｍｂＨ |
ジユビキチン変異タンパク質をベースとした新規結合タンパク質及びその生成方法
|
|
WO2017147265A1
(en)
|
2016-02-23 |
2017-08-31 |
Salk Institute For Biological Studies |
High throughput assay for measuring adenovirus replication kinetics
|
|
EP3390645B1
(en)
|
2016-02-23 |
2022-09-14 |
Salk Institute for Biological Studies |
Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics
|
|
AU2017260274A1
(en)
|
2016-05-04 |
2018-11-01 |
Navigo Proteins Gmbh |
Targeted compounds for the site-specific coupling of chemical moieties comprising a peptide linker
|
|
US11230576B2
(en)
|
2016-08-11 |
2022-01-25 |
Navigo Proteins Gmbh |
Alkaline stable immunoglobulin-binding proteins
|
|
WO2018035387A1
(en)
|
2016-08-17 |
2018-02-22 |
The Broad Institute, Inc. |
Novel crispr enzymes and systems
|
|
US11352647B2
(en)
|
2016-08-17 |
2022-06-07 |
The Broad Institute, Inc. |
Crispr enzymes and systems
|
|
AU2017375633C1
(en)
|
2016-12-12 |
2023-04-27 |
Salk Institute For Biological Studies |
Tumor-targeting synthetic adenoviruses and uses thereof
|
|
WO2018191750A2
(en)
|
2017-04-14 |
2018-10-18 |
The Broad Institute Inc. |
Novel delivery of large payloads
|
|
US12227742B2
(en)
|
2017-10-23 |
2025-02-18 |
The Broad Institute, Inc. |
Nucleic acid modifiers
|
|
WO2019091918A1
(en)
|
2017-11-07 |
2019-05-16 |
Navigo Proteins Gmbh |
Fusion proteins with specificity for ed-b and long serum half-life for diagnosis or treatment of cancer
|
|
WO2019094983A1
(en)
|
2017-11-13 |
2019-05-16 |
The Broad Institute, Inc. |
Methods and compositions for treating cancer by targeting the clec2d-klrb1 pathway
|
|
BR112020019942A2
(pt)
|
2018-04-09 |
2021-01-26 |
Salk Institute For Biological Studies |
composições de adenovírus oncolítico com propriedades de replicação aprimoradas
|
|
WO2020131862A1
(en)
|
2018-12-17 |
2020-06-25 |
The Broad Institute, Inc. |
Crispr-associated transposase systems and methods of use thereof
|
|
KR20210104106A
(ko)
|
2018-12-18 |
2021-08-24 |
나피고 프로타인스 게엠베하 |
암 진단 및 치료를 위한 신규 folr1 특이적 결합 단백질
|
|
US20220220469A1
(en)
|
2019-05-20 |
2022-07-14 |
The Broad Institute, Inc. |
Non-class i multi-component nucleic acid targeting systems
|
|
US12297426B2
(en)
|
2019-10-01 |
2025-05-13 |
The Broad Institute, Inc. |
DNA damage response signature guided rational design of CRISPR-based systems and therapies
|
|
US11149286B1
(en)
|
2020-08-17 |
2021-10-19 |
Mayo Foundation For Medical Education And Research |
Adenovirus vectors and methods for using adenovirus vectors
|
|
AU2023250649A1
(en)
|
2022-04-04 |
2024-11-14 |
The Regents Of The University Of California |
Genetic complementation compositions and methods
|
|
WO2025072383A1
(en)
|
2023-09-25 |
2025-04-03 |
The Broad Institute, Inc. |
Viral open reading frames, uses thereof, and methods of detecting the same
|
|
WO2025097055A2
(en)
|
2023-11-02 |
2025-05-08 |
The Broad Institute, Inc. |
Compositions and methods of use of t cells in immunotherapy
|
|
WO2025129158A1
(en)
|
2023-12-15 |
2025-06-19 |
The Broad Institute, Inc. |
Engineered arc delivery vesicles and uses thereof
|
|
WO2025250808A1
(en)
|
2024-05-29 |
2025-12-04 |
The Brigham And Women’S Hospital, Inc. |
Anti-crispr delivery compositions and methods
|