JP2001520112A - マイクロミキサー - Google Patents

マイクロミキサー

Info

Publication number
JP2001520112A
JP2001520112A JP2000516764A JP2000516764A JP2001520112A JP 2001520112 A JP2001520112 A JP 2001520112A JP 2000516764 A JP2000516764 A JP 2000516764A JP 2000516764 A JP2000516764 A JP 2000516764A JP 2001520112 A JP2001520112 A JP 2001520112A
Authority
JP
Japan
Prior art keywords
passage
micromixer
housing
phases
grooves
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2000516764A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001520112A5 (https=
Inventor
ウルリッヒ クープ，
ミヒャエル シュメルツ，
アンドレアス バイラウ，
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Publication of JP2001520112A publication Critical patent/JP2001520112A/ja
Publication of JP2001520112A5 publication Critical patent/JP2001520112A5/ja
Pending legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/30—Micromixers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
    • B01F25/40—Static mixers
    • B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
    • B01F25/43—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction
    • B01F25/432—Mixing tubes, e.g. wherein the material is moved in a radial or partly reversed direction with means for dividing the material flow into separate sub-flows and for repositioning and recombining these sub-flows; Cross-mixing, e.g. conducting the outer layer of the material nearer to the axis of the tube or vice-versa
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/10—Mixing gases with gases
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F23/00—Mixing according to the phases to be mixed, e.g. dispersing or emulsifying
    • B01F23/40—Mixing liquids with liquids; Emulsifying
    • B01F23/47—Mixing liquids with liquids; Emulsifying involving high-viscosity liquids, e.g. asphalt
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00824—Ceramic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00831—Glass
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00819—Materials of construction
    • B01J2219/00833—Plastic
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00873—Heat exchange
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00889—Mixing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00781—Aspects relating to microreactors
    • B01J2219/00891—Feeding or evacuation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
JP2000516764A 1997-10-22 1998-10-12 マイクロミキサー Pending JP2001520112A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19746583A DE19746583A1 (de) 1997-10-22 1997-10-22 Mikromischer
DE19746583.8 1997-10-22
PCT/EP1998/006462 WO1999020379A1 (de) 1997-10-22 1998-10-12 Mikromischer

Publications (2)

Publication Number Publication Date
JP2001520112A true JP2001520112A (ja) 2001-10-30
JP2001520112A5 JP2001520112A5 (https=) 2006-01-05

Family

ID=7846245

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000516764A Pending JP2001520112A (ja) 1997-10-22 1998-10-12 マイクロミキサー

Country Status (6)

Country Link
US (1) US6457854B1 (https=)
EP (1) EP1047489B1 (https=)
JP (1) JP2001520112A (https=)
KR (1) KR100518060B1 (https=)
DE (2) DE19746583A1 (https=)
WO (1) WO1999020379A1 (https=)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007502979A (ja) * 2003-08-19 2007-02-15 バイエル・ヘルスケア・エルエルシー マイクロ流体装置における混合
JP2008238168A (ja) * 2008-04-14 2008-10-09 Konica Minolta Holdings Inc 液体混合機構
JP2008246283A (ja) * 2007-03-29 2008-10-16 Okayama Prefecture Industrial Promotion Foundation 衝突型マイクロミキサー
WO2011027570A1 (ja) * 2009-09-04 2011-03-10 日曹エンジニアリング株式会社 流通式管型反応装置
WO2013021877A1 (en) * 2011-08-11 2013-02-14 Canon Kabushiki Kaisha Fluidic channel device, method for mixing fluids, fluid control device, and liquid control system
WO2013054742A1 (ja) * 2011-10-11 2013-04-18 株式会社日立ハイテクノロジーズ 流体混合器及び流体混合方法
KR101736797B1 (ko) * 2016-01-29 2017-05-17 인하대학교 산학협력단 미세 유체 혼합기
JP2018505040A (ja) * 2014-12-08 2018-02-22 ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ 流体混合構造、連続反応ユニット、連続反応反応器、およびその使用方法
JP2020514397A (ja) * 2017-03-24 2020-05-21 アモーレパシフィック コーポレーションＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ 瞬間乳化化粧品製造装置および製造方法

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DE29903296U1 (de) * 1999-02-24 2000-08-03 CPC Cellular Process Chemistry GmbH, 60386 Frankfurt Mikroreaktor
DE19911776A1 (de) 1999-03-17 2000-09-21 Merck Patent Gmbh Verpackungssysteme für kosmetische Formulierungen
DE19911777A1 (de) * 1999-03-17 2000-09-21 Merck Patent Gmbh Verfahren zur Herstellung von kosmetischen Formulierungen
GB2355543A (en) * 1999-10-20 2001-04-25 Univ Sheffield Fluidic flow control and fluidic device
DE10001317A1 (de) * 2000-01-14 2001-07-19 Merck Patent Gmbh Reaktion von Carbonylverbindungen mit metallorganischen Reagenzien
US7905653B2 (en) * 2001-07-31 2011-03-15 Mega Fluid Systems, Inc. Method and apparatus for blending process materials
DE10159985B4 (de) * 2001-12-06 2008-02-28 Schwesinger, Norbert, Prof.Dr.-Ing. Mikroemulgator
DE10218280C1 (de) * 2002-04-19 2003-11-20 Fraunhofer Ges Forschung Integriertes Misch- und Schaltsystem für die Mikroreaktionstechnik
WO2004007346A2 (en) * 2002-07-16 2004-01-22 Mixtek System, Llc Aerosol mixing system with columns
KR100472058B1 (ko) * 2002-11-02 2005-03-11 한국전자통신연구원 미소유체 혼합을 위한 미소 유체제어 소자
DE10254534A1 (de) * 2002-11-22 2004-06-09 Henkel Kgaa Vorrichtung zum Vermischen von wenigstens zwei Flüssigkeiten
US7094354B2 (en) 2002-12-19 2006-08-22 Bayer Healthcare Llc Method and apparatus for separation of particles in a microfluidic device
US7125711B2 (en) 2002-12-19 2006-10-24 Bayer Healthcare Llc Method and apparatus for splitting of specimens into multiple channels of a microfluidic device
US7485671B2 (en) * 2003-05-16 2009-02-03 Velocys, Inc. Process for forming an emulsion using microchannel process technology
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KR100658361B1 (ko) * 2005-09-12 2006-12-15 주식회사 스펙 마이크로 채널 리액터
DE102005012415B4 (de) * 2005-03-17 2006-12-28 Syntics Gmbh Verfahrenstechnisches Funktionselement aus einem Folienstapel
US7314060B2 (en) * 2005-04-23 2008-01-01 Industrial Technology Research Institute Fluid flow conducting module
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US20060285433A1 (en) * 2005-06-20 2006-12-21 Jing-Tang Yang Fluidic mixer of serpentine channel incorporated with staggered sudden-expansion and convergent cross sections
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DE102005060280B4 (de) * 2005-12-16 2018-12-27 Ehrfeld Mikrotechnik Bts Gmbh Integrierbarer Mikromischer sowie dessen Verwendung
KR100898065B1 (ko) 2007-10-19 2009-05-15 송상섭 마이크로 리액터
KR101113727B1 (ko) * 2008-02-18 2012-02-27 주식회사 올메디쿠스 수직 적층식 마이크로 믹서 및 그 제조방법
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KR101005676B1 (ko) * 2008-11-27 2011-01-05 인하대학교 산학협력단 수동형 미세혼합기
JP2012519577A (ja) 2009-03-06 2012-08-30 エールフエルト・ミクロテヒニク・ベー・テー・エス・ゲー・エム・ベー・ハー 同軸の小型のスタティックミキサおよびその使用
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CN102401760B (zh) * 2011-11-04 2014-05-07 华中科技大学 十字型三维水力聚焦微混合装置
CN102513011B (zh) * 2011-11-24 2013-10-30 华中科技大学 一种基于三维水力聚焦的微混合装置
KR101666425B1 (ko) * 2013-11-25 2016-10-14 주식회사 엘지화학 미세 유로 반응기
WO2015184302A1 (en) 2014-05-30 2015-12-03 Microfluidics Corporation Interaction chambers with reduced cavitation
WO2016138175A1 (en) 2015-02-24 2016-09-01 The University Of British Columbia Continuous flow microfluidic system
US10035113B2 (en) * 2015-02-26 2018-07-31 Tokyo Electron Limited Method and system for a spiral mixer
EP3288671A4 (en) 2015-04-28 2019-01-16 The University Of British Columbia DISPOSABLE MICROFLUIDIC CARTRIDGE
CN105056821B (zh) * 2015-08-17 2017-05-03 江苏大学 一种对称椭圆弧挡板的十字微混合器
EP3400097B1 (en) * 2016-01-06 2021-01-27 The University Of British Columbia Bifurcating mixers and methods of their use and manufacture
CN105771765B (zh) * 2016-03-30 2018-02-27 江苏大学 一种内置周期性阻块和挡板的被动式微混合器
CN106268471B (zh) * 2016-08-05 2019-02-05 江苏大学 一种渐缩弯管串联式微混合器
US10603647B2 (en) * 2016-12-01 2020-03-31 Imagine Tf, Llc Microstructure flow mixing devices
CN110634723B (zh) * 2018-06-21 2022-07-05 中微半导体设备(上海)股份有限公司 一种耐腐蚀的气体混合装置及等离子体处理设备
CN109092225B (zh) * 2018-11-02 2024-06-07 南京正源搪瓷设备制造有限公司 红心k型微反应器
CN109647307A (zh) * 2019-01-28 2019-04-19 北京理工大学 Y型组合式微通道结构
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CN117899778B (zh) * 2024-03-04 2025-06-17 广东省科学院新材料研究所 一种微通道反应器及其制备方法

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Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007502979A (ja) * 2003-08-19 2007-02-15 バイエル・ヘルスケア・エルエルシー マイクロ流体装置における混合
JP2008246283A (ja) * 2007-03-29 2008-10-16 Okayama Prefecture Industrial Promotion Foundation 衝突型マイクロミキサー
JP2008238168A (ja) * 2008-04-14 2008-10-09 Konica Minolta Holdings Inc 液体混合機構
WO2011027570A1 (ja) * 2009-09-04 2011-03-10 日曹エンジニアリング株式会社 流通式管型反応装置
WO2013021877A1 (en) * 2011-08-11 2013-02-14 Canon Kabushiki Kaisha Fluidic channel device, method for mixing fluids, fluid control device, and liquid control system
JP2013040776A (ja) * 2011-08-11 2013-02-28 Canon Inc 流路デバイスおよび流体の混合方法
WO2013054742A1 (ja) * 2011-10-11 2013-04-18 株式会社日立ハイテクノロジーズ 流体混合器及び流体混合方法
JP2013081911A (ja) * 2011-10-11 2013-05-09 Hitachi High-Technologies Corp 流体混合器及び流体混合方法
JP2018505040A (ja) * 2014-12-08 2018-02-22 ロンザ リミテッドＬｏｎｚａ Ｌｉｍｉｔｅｄ 流体混合構造、連続反応ユニット、連続反応反応器、およびその使用方法
KR101736797B1 (ko) * 2016-01-29 2017-05-17 인하대학교 산학협력단 미세 유체 혼합기
JP2020514397A (ja) * 2017-03-24 2020-05-21 アモーレパシフィック コーポレーションＡｍｏｒｅｐａｃｉｆｉｃ Ｃｏｒｐｏｒａｔｉｏｎ 瞬間乳化化粧品製造装置および製造方法
JP7478539B2 (ja) 2017-03-24 2024-05-07 アモーレパシフィック コーポレーション 瞬間乳化化粧品製造装置および製造方法

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DE19746583A1 (de) 1999-04-29
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EP1047489B1 (de) 2002-09-11
DE59805556D1 (de) 2002-10-17
KR20010024538A (ko) 2001-03-26
EP1047489A1 (en) 2000-11-02
KR100518060B1 (ko) 2005-09-28

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