JP2001517447A5 - - Google Patents
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- Publication number
- JP2001517447A5 JP2001517447A5 JP2000512962A JP2000512962A JP2001517447A5 JP 2001517447 A5 JP2001517447 A5 JP 2001517447A5 JP 2000512962 A JP2000512962 A JP 2000512962A JP 2000512962 A JP2000512962 A JP 2000512962A JP 2001517447 A5 JP2001517447 A5 JP 2001517447A5
- Authority
- JP
- Japan
- Prior art keywords
- fragment
- polypeptide
- amino acids
- region
- hbv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 108090000765 processed proteins & peptides Proteins 0.000 description 11
- 229920001184 polypeptide Polymers 0.000 description 10
- 102000004196 processed proteins & peptides Human genes 0.000 description 10
- 239000012634 fragment Substances 0.000 description 7
- 241000700721 Hepatitis B virus Species 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 6
- 102000040430 polynucleotide Human genes 0.000 description 5
- 108091033319 polynucleotide Proteins 0.000 description 5
- 239000002157 polynucleotide Substances 0.000 description 5
- 239000008194 pharmaceutical composition Substances 0.000 description 3
- 241001465754 Metazoa Species 0.000 description 2
- 239000004480 active ingredient Substances 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 230000001105 regulatory effect Effects 0.000 description 2
- 108010044241 tetanus toxin fragment C Proteins 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 101150018266 degP gene Proteins 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 101150007310 htrA gene Proteins 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 229960005486 vaccine Drugs 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9720033.1A GB9720033D0 (en) | 1997-09-19 | 1997-09-19 | Hepatitis B virus polypeptides |
| GB9720033.1 | 1997-09-19 | ||
| PCT/GB1998/002852 WO1999015671A1 (en) | 1997-09-19 | 1998-09-21 | Hepatitis b virus polypeptides |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001517447A JP2001517447A (ja) | 2001-10-09 |
| JP2001517447A5 true JP2001517447A5 (enExample) | 2006-01-05 |
Family
ID=10819394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000512962A Pending JP2001517447A (ja) | 1997-09-19 | 1998-09-21 | Ｂ型肝炎ウイルスポリペプチド |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US20040258709A1 (enExample) |
| EP (1) | EP1015593B1 (enExample) |
| JP (1) | JP2001517447A (enExample) |
| KR (1) | KR100637282B1 (enExample) |
| AT (1) | ATE241013T1 (enExample) |
| AU (1) | AU751646B2 (enExample) |
| CA (1) | CA2304255C (enExample) |
| CZ (1) | CZ297131B6 (enExample) |
| DE (1) | DE69814884T2 (enExample) |
| ES (1) | ES2199460T3 (enExample) |
| GB (1) | GB9720033D0 (enExample) |
| HU (1) | HUP0003511A3 (enExample) |
| NO (1) | NO20001397L (enExample) |
| PL (1) | PL195242B1 (enExample) |
| WO (1) | WO1999015671A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0009470D0 (en) | 2000-04-17 | 2000-06-07 | Univ Southampton | Materials and methods relating to immune responses to fusion proteins |
| EP1281761A1 (en) * | 2001-07-27 | 2003-02-05 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Hepatitis B virus pre-S1 derived synthetic polypeptides and their use thereof. |
| CA2530363C (en) * | 2003-06-23 | 2013-05-07 | Baxter International Inc. | Carrier proteins for vaccines |
| CN100537762C (zh) * | 2004-06-24 | 2009-09-09 | 中国人民解放军军事医学科学院野战输血研究所 | 一种嵌合型病毒样颗粒疫苗载体蛋白及其制备方法与应用 |
| CN111499722B (zh) | 2012-11-12 | 2024-08-23 | 海德堡吕布莱希特-卡尔斯大学 | 用于治疗肝脏疾病和心血管疾病的脂肽 |
| CN121646478A (zh) * | 2023-06-23 | 2026-03-10 | 腾盛博药生物科技有限公司 | 慢性乙型肝炎的评估与治疗 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1341074C (en) * | 1987-06-22 | 2000-08-08 | Hans A. Thoma | Hbv surface antigen particles, prepared by recombinant dna processes, composed of different epitopes, selected from the pre-s and s-peptides as a new vaccine |
| EP0389983A3 (en) * | 1989-03-31 | 1991-01-16 | Abbott Laboratories | Monoclonal antibodies to pres2 and pres1 polypeptides of the hepatitis b viral envelope |
| WO1994001132A1 (en) * | 1992-07-07 | 1994-01-20 | Merck & Co., Inc. | VACCINE COMPRISING MIXED preS1+preS2+S AND CORE PARTICLE |
| ES2127829T3 (es) * | 1992-07-31 | 1999-05-01 | Medeva Holdings Bv | Expresion de proteinas recombinantes fusionadas en bacterias atenuadas. |
| EP0712442B1 (en) * | 1993-07-30 | 2002-03-27 | Medeva Holdings B.V. | Vaccine compositions |
| GB9401795D0 (en) * | 1994-01-31 | 1994-03-23 | Medeva Holdings Bv | Vaccines |
-
1997
- 1997-09-19 GB GBGB9720033.1A patent/GB9720033D0/en not_active Ceased
-
1998
- 1998-09-21 PL PL98339366A patent/PL195242B1/pl not_active IP Right Cessation
- 1998-09-21 AT AT98944071T patent/ATE241013T1/de not_active IP Right Cessation
- 1998-09-21 CA CA002304255A patent/CA2304255C/en not_active Expired - Fee Related
- 1998-09-21 AU AU91744/98A patent/AU751646B2/en not_active Ceased
- 1998-09-21 KR KR1020007002945A patent/KR100637282B1/ko not_active Expired - Fee Related
- 1998-09-21 HU HU0003511A patent/HUP0003511A3/hu unknown
- 1998-09-21 ES ES98944071T patent/ES2199460T3/es not_active Expired - Lifetime
- 1998-09-21 DE DE69814884T patent/DE69814884T2/de not_active Expired - Fee Related
- 1998-09-21 EP EP98944071A patent/EP1015593B1/en not_active Expired - Lifetime
- 1998-09-21 CZ CZ20000978A patent/CZ297131B6/cs not_active IP Right Cessation
- 1998-09-21 JP JP2000512962A patent/JP2001517447A/ja active Pending
- 1998-09-21 WO PCT/GB1998/002852 patent/WO1999015671A1/en not_active Ceased
-
2000
- 2000-03-17 NO NO20001397A patent/NO20001397L/no not_active Application Discontinuation
-
2004
- 2004-07-15 US US10/892,018 patent/US20040258709A1/en not_active Abandoned
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