|
AU7667498A
(en)
*
|
1997-05-30 |
1998-12-30 |
Celltech Therapeutics Limited |
Anti-inflammatory tyrosine derivatives
|
|
AU8163398A
(en)
|
1997-06-23 |
1999-01-04 |
Pharmacia & Upjohn Company |
Inhibitors of alpha4beta1mediated cell adhesion
|
|
US6939855B2
(en)
|
1997-07-31 |
2005-09-06 |
Elan Pharmaceuticals, Inc. |
Anti-inflammatory compositions and method
|
|
US6423688B1
(en)
|
1997-07-31 |
2002-07-23 |
Athena Neurosciences, Inc. |
Dipeptide and related compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6291453B1
(en)
|
1997-07-31 |
2001-09-18 |
Athena Neurosciences, Inc. |
4-amino-phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6362341B1
(en)
|
1997-07-31 |
2002-03-26 |
Athena Neurosciences, Inc. |
Benzyl compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US7030114B1
(en)
|
1997-07-31 |
2006-04-18 |
Elan Pharmaceuticals, Inc. |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6489300B1
(en)
|
1997-07-31 |
2002-12-03 |
Eugene D. Thorsett |
Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6492421B1
(en)
|
1997-07-31 |
2002-12-10 |
Athena Neurosciences, Inc. |
Substituted phenylalanine type compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6559127B1
(en)
|
1997-07-31 |
2003-05-06 |
Athena Neurosciences, Inc. |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6583139B1
(en)
|
1997-07-31 |
2003-06-24 |
Eugene D. Thorsett |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6645939B1
(en)
|
1997-11-24 |
2003-11-11 |
Merck & Co., Inc. |
Substituted β-alanine derivatives as cell adhesion inhibitors
|
|
MY153569A
(en)
|
1998-01-20 |
2015-02-27 |
Mitsubishi Tanabe Pharma Corp |
Inhibitors of ?4 mediated cell adhesion
|
|
US6329372B1
(en)
|
1998-01-27 |
2001-12-11 |
Celltech Therapeutics Limited |
Phenylalanine derivatives
|
|
DE69919334T2
(de)
|
1998-02-26 |
2005-08-04 |
Celltech Therapeutics Ltd., Slough |
Phenylalaninderivate als inhibitoren von alpha4 integrinen
|
|
US6521626B1
(en)
|
1998-03-24 |
2003-02-18 |
Celltech R&D Limited |
Thiocarboxamide derivatives
|
|
GB9811159D0
(en)
|
1998-05-22 |
1998-07-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9811969D0
(en)
|
1998-06-03 |
1998-07-29 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
US6685617B1
(en)
|
1998-06-23 |
2004-02-03 |
Pharmacia & Upjohn Company |
Inhibitors of α4β1 mediated cell adhesion
|
|
GB9814414D0
(en)
|
1998-07-03 |
1998-09-02 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9821061D0
(en)
|
1998-09-28 |
1998-11-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9821222D0
(en)
|
1998-09-30 |
1998-11-25 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9825652D0
(en)
|
1998-11-23 |
1999-01-13 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9826174D0
(en)
|
1998-11-30 |
1999-01-20 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
GB9828074D0
(en)
*
|
1998-12-18 |
1999-02-17 |
Glaxo Group Ltd |
Therapeutically useful compounds
|
|
EP1150951A1
(en)
*
|
1998-12-31 |
2001-11-07 |
Aventis Pharmaceuticals Inc. |
3-substituted pyrrolidines useful as inhibitors of matrix metallo-proteinases
|
|
US6486193B2
(en)
|
1998-12-31 |
2002-11-26 |
Aventis Pharmaceuticals Inc. |
3-substituted pyrrolidines useful as inhibitors of matrix metalloproteinases
|
|
ATE455106T1
(de)
|
1999-01-22 |
2010-01-15 |
Elan Pharm Inc |
Acyl derivate zur behandlung von krankheiten die in zusammenhang mit vla-4 stehen
|
|
HK1043794A1
(zh)
|
1999-01-22 |
2002-09-27 |
依兰制药公司 |
抑制vla-4介导的白细胞粘附的稠合环杂芳基和杂环化合物
|
|
US6436904B1
(en)
|
1999-01-25 |
2002-08-20 |
Elan Pharmaceuticals, Inc. |
Compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
JP2002539080A
(ja)
*
|
1999-01-25 |
2002-11-19 |
エラン ファーマシューティカルズ，インコーポレイテッド |
Ｖｌａ−４によって媒介される白血球接着を阻害する化合物
|
|
US6407066B1
(en)
|
1999-01-26 |
2002-06-18 |
Elan Pharmaceuticals, Inc. |
Pyroglutamic acid derivatives and related compounds which inhibit leukocyte adhesion mediated by VLA-4
|
|
US6518283B1
(en)
|
1999-05-28 |
2003-02-11 |
Celltech R&D Limited |
Squaric acid derivatives
|
|
US6756378B2
(en)
|
1999-06-30 |
2004-06-29 |
Pharmacopeia Drug Discovery, Inc. |
VLA-4 inhibitor compounds
|
|
GB2354440A
(en)
*
|
1999-07-20 |
2001-03-28 |
Merck & Co Inc |
Aryl amides as cell adhesion inhibitors
|
|
CZ2002518A3
(cs)
|
1999-08-13 |
2002-05-15 |
Biogen, Inc. |
Inhibitory buněčné adheze a farmaceutické prostředky, které je obsahují
|
|
US6534513B1
(en)
|
1999-09-29 |
2003-03-18 |
Celltech R&D Limited |
Phenylalkanoic acid derivatives
|
|
DE60034061T2
(de)
*
|
1999-12-06 |
2007-12-13 |
F. Hoffmann-La Roche Ag |
4-pyrimidinyl-n-acyl-l-phenylanine
|
|
US6380387B1
(en)
|
1999-12-06 |
2002-04-30 |
Hoffmann-La Roche Inc. |
4-Pyrimidinyl-n-acyl-l phenylalanines
|
|
US6388084B1
(en)
|
1999-12-06 |
2002-05-14 |
Hoffmann-La Roche Inc. |
4-pyridinyl-n-acyl-l-phenylalanines
|
|
CZ20022352A3
(cs)
*
|
1999-12-06 |
2003-05-14 |
F. Hoffmann-La Roche Ag |
4-pyridinyl-N-acyl-L-fenylalaniny
|
|
US6455539B2
(en)
|
1999-12-23 |
2002-09-24 |
Celltech R&D Limited |
Squaric acid derivates
|
|
DE19962936A1
(de)
|
1999-12-24 |
2001-06-28 |
Bayer Ag |
Neue beta-Aminosäureverbindungen als Integrinantagonisten
|
|
YU41202A
(sh)
|
1999-12-28 |
2005-03-15 |
Pfizer Products Inc. |
Ne-peptidni inhibitori vezivanja za ćeliju zavisnog od vla-4 korisni pri tretiranju inflamatornih, autoimunih i respiratornih bolesti
|
|
DE60130910T2
(de)
|
2000-04-17 |
2008-07-10 |
Ucb Pharma, S.A. |
Enamin-derivate als zell-adhäsionsmoleküle
|
|
US6545013B2
(en)
|
2000-05-30 |
2003-04-08 |
Celltech R&D Limited |
2,7-naphthyridine derivatives
|
|
US6403608B1
(en)
|
2000-05-30 |
2002-06-11 |
Celltech R&D, Ltd. |
3-Substituted isoquinolin-1-yl derivatives
|
|
US6960597B2
(en)
*
|
2000-06-30 |
2005-11-01 |
Orth-Mcneil Pharmaceutical, Inc. |
Aza-bridged-bicyclic amino acid derivatives as α4 integrin antagonists
|
|
US6740654B2
(en)
|
2000-07-07 |
2004-05-25 |
Celltech R & D Limited |
Squaric acid derivatives
|
|
AU2001275724A1
(en)
|
2000-08-02 |
2002-02-13 |
Celltech R&D Limited |
3-substituted isoquinolin-1-yl derivatives
|
|
MY129000A
(en)
|
2000-08-31 |
2007-03-30 |
Tanabe Seiyaku Co |
INHIBITORS OF a4 MEDIATED CELL ADHESION
|
|
JP5260818B2
(ja)
*
|
2000-09-29 |
2013-08-14 |
ノバルティス・インターナショナル・ファーマシューティカル・リミテッド |
高親和性低分子Ｃ５ａ受容体調節物質
|
|
AR038957A1
(es)
|
2001-08-15 |
2005-02-02 |
Pharmacia Corp |
Terapia de combinacion para el tratamiento del cancer
|
|
DK1485127T3
(da)
|
2002-02-25 |
2011-10-03 |
Elan Pharm Inc |
Anvendelse af midler til behandling af inflammation
|
|
TW200307671A
(en)
|
2002-05-24 |
2003-12-16 |
Elan Pharm Inc |
Heteroaryl compounds which inhibit leukocyte adhesion mediated by α 4 integrins
|
|
TWI281470B
(en)
|
2002-05-24 |
2007-05-21 |
Elan Pharm Inc |
Heterocyclic compounds which inhibit leukocyte adhesion mediated by alpha4 integrins
|
|
AU2003265398A1
(en)
|
2002-08-09 |
2004-02-25 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds and methods to modulate coagulation
|
|
WO2004041279A1
(en)
|
2002-10-30 |
2004-05-21 |
Merck & Co., Inc. |
Gamma-aminoamide modulators of chemokine receptor activity
|
|
CA2514117A1
(en)
*
|
2003-01-24 |
2004-08-12 |
Elan Pharmaceuticals, Inc. |
Composition for and treatment of demyelinating diseases and paralysis by administration of remyelinating agents
|
|
US7208601B2
(en)
|
2003-08-08 |
2007-04-24 |
Mjalli Adnan M M |
Aryl and heteroaryl compounds, compositions, and methods of use
|
|
US7544699B2
(en)
|
2003-08-08 |
2009-06-09 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions, and methods of use
|
|
US7501538B2
(en)
|
2003-08-08 |
2009-03-10 |
Transtech Pharma, Inc. |
Aryl and heteroaryl compounds, compositions and methods of use
|
|
EA015517B1
(ru)
|
2004-04-13 |
2011-08-30 |
Инсайт Корпорейшн |
Производные пиперазинилпиперидина в качестве антагонистов хемокинового рецептора
|
|
FR2869904B1
(fr)
*
|
2004-05-07 |
2006-07-28 |
Fournier S A Sa Lab |
Modulateurs des recepteurs lxr
|
|
US7794700B2
(en)
|
2004-07-08 |
2010-09-14 |
Elan Pharmaceuticals Inc. |
Multimeric VLA-4 antagonists comprising polymer moieties
|
|
US7196112B2
(en)
|
2004-07-16 |
2007-03-27 |
Biogen Idec Ma Inc. |
Cell adhesion inhibitors
|
|
BRPI0616687A2
(pt)
|
2005-09-29 |
2011-06-28 |
Elan Pharm Inc |
compostos de pirimidinil amida que inibem a adesão leucocitária mediada por vla-4
|
|
CA2624524C
(en)
|
2005-09-29 |
2014-07-08 |
Elan Pharmaceuticals, Inc. |
Carbamate compounds which inhibit leukocyte adhesion mediated by vla-4
|
|
MEP1008A
(xx)
|
2005-12-21 |
2010-02-10 |
Incyte Corp |
3-aminociklopentankarboksamidi kao modulatori receptora hemokina
|
|
CA2643838A1
(en)
|
2006-02-27 |
2007-09-07 |
Elan Pharmaceuticals, Inc. |
Pyrimidinyl sulfonamide compounds which inhibit leukocyte adhesion mediated by vla-4
|
|
TW200811164A
(en)
*
|
2006-05-12 |
2008-03-01 |
Jerini Ag |
New heterocyclic compounds for the inhibition of integrins and use thereof
|
|
WO2008103378A2
(en)
|
2007-02-20 |
2008-08-28 |
Merrimack Pharmaceuticals, Inc. |
Methods of treating multiple sclerosis by administration of alpha-fetoprotein in combination with an integrin antagonist
|
|
MX2010011145A
(es)
|
2008-04-11 |
2011-04-11 |
Merrimack Pharmaceuticals Inc |
Enlazadores de la albumina de suero humana y conjugados de la misma.
|
|
EP2370442B9
(en)
|
2008-11-26 |
2013-09-04 |
Pfizer Inc. |
3-Aminocyclopentanecarboxamides as chemokine receptor modulators
|
|
TW201041892A
(en)
|
2009-02-09 |
2010-12-01 |
Supergen Inc |
Pyrrolopyrimidinyl Axl kinase inhibitors
|
|
JP5466759B2
(ja)
|
2009-05-28 |
2014-04-09 |
ノバルティス アーゲー |
ネプリライシン阻害剤としての置換アミノ酪酸誘導体
|
|
SG176009A1
(en)
|
2009-05-28 |
2011-12-29 |
Novartis Ag |
Substituted aminopropionic derivatives as neprilysin inhibitors
|
|
JO2967B1
(en)
|
2009-11-20 |
2016-03-15 |
نوفارتس ايه جي |
Acetic acid derivatives of carbamoyl methyl amino are substituted as new NEP inhibitors
|
|
TR201808541T4
(tr)
|
2013-02-14 |
2018-07-23 |
Novartis Ag |
Nep (nötr endopeptidaz) inhibitörleri olarak ikame edilmiş bisfenil butanoik fosfonik asit türevleri.
|
|
JP6301371B2
(ja)
|
2013-02-14 |
2018-04-11 |
ノバルティス アーゲー |
インビボ効力が改善されたｎｅｐ阻害剤としての置換ビスフェニルブタン酸誘導体
|
|
KR20170052526A
(ko)
|
2014-03-13 |
2017-05-12 |
프로테나 바이오사이언시즈 리미티드 |
다발성 경화증에 대한 병용 치료
|
|
WO2018085578A1
(en)
*
|
2016-11-02 |
2018-05-11 |
Saint Louis University |
Integrin inhibitors in combination with an agent which interacts with a chemokine receptor
|
|
EP3873605B1
(en)
|
2018-10-30 |
2024-10-23 |
Gilead Sciences, Inc. |
Compounds for inhibition of alpha4beta7 integrin
|
|
FI3873884T3
(fi)
|
2018-10-30 |
2025-02-24 |
Gilead Sciences Inc |
3-(kinolin-8-yyli)-1,4-dihydropyrido[3,4-d]pyrimidiini-2,4-dionijohdannaisia alfa-4-beta-7-integriinin estäjinä tulehdussairauksien hoidossa
|
|
JP7189368B2
(ja)
|
2018-10-30 |
2022-12-13 |
ギリアード サイエンシーズ， インコーポレイテッド |
アルファ４ベータ７インテグリンの阻害のための化合物
|
|
ES3013256T3
(en)
|
2018-10-30 |
2025-04-11 |
Gilead Sciences Inc |
Imidazo[1,2-a]pyridine derivatives as alpha4beta7 integrin inhibitors for the treatment of inflammatory diseases
|
|
WO2021030438A1
(en)
|
2019-08-14 |
2021-02-18 |
Gilead Sciences, Inc. |
Compounds for inhibition of alpha 4 beta 7 integrin
|
|
PH12022553378A1
(en)
|
2020-06-10 |
2024-03-25 |
Univ Leuven Kath |
Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections
|
|
AU2022306289A1
(en)
|
2021-07-09 |
2024-01-18 |
Aligos Therapeutics, Inc. |
Anti-viral compounds
|
|
WO2023043816A1
(en)
|
2021-09-17 |
2023-03-23 |
Aligos Therapeutics, Inc. |
Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections
|