JP2001515708A5 - - Google Patents
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- Publication number
- JP2001515708A5 JP2001515708A5 JP2000510463A JP2000510463A JP2001515708A5 JP 2001515708 A5 JP2001515708 A5 JP 2001515708A5 JP 2000510463 A JP2000510463 A JP 2000510463A JP 2000510463 A JP2000510463 A JP 2000510463A JP 2001515708 A5 JP2001515708 A5 JP 2001515708A5
- Authority
- JP
- Japan
- Prior art keywords
- heavy chain
- antibody
- humanized
- sasnryt
- ngfwi
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/925,339 US6440418B1 (en) | 1995-11-07 | 1997-09-08 | Methods of treating autoimmune diseases with gp39-specific antibodies |
| US08/925,339 | 1997-09-08 | ||
| PCT/US1998/018163 WO1999012566A1 (en) | 1997-09-08 | 1998-09-08 | HUMANIZED ANTIBODIES TO HUMAN gp39, COMPOSITIONS CONTAINING AND THERAPEUTIC USE THEREOF |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2001515708A JP2001515708A (ja) | 2001-09-25 |
| JP2001515708A5 true JP2001515708A5 (https=) | 2006-07-06 |
Family
ID=25451580
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2000510463A Abandoned JP2001515708A (ja) | 1997-09-08 | 1998-09-08 | ヒトgp39に対するヒト化抗体、当該抗体を含む組成物およびその治療的使用 |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6440418B1 (https=) |
| EP (1) | EP1011725A4 (https=) |
| JP (1) | JP2001515708A (https=) |
| KR (1) | KR100574591B1 (https=) |
| CN (1) | CN1278736A (https=) |
| AU (1) | AU740981B2 (https=) |
| CA (1) | CA2302752A1 (https=) |
| IL (1) | IL134888A0 (https=) |
| NO (1) | NO20001104L (https=) |
| RU (1) | RU2207878C2 (https=) |
| WO (1) | WO1999012566A1 (https=) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6001358A (en) | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
| US6440418B1 (en) * | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
| CN1247472A (zh) * | 1997-01-10 | 2000-03-15 | 拜奥根有限公司 | 用抗cd40l化合物治疗狼疮性肾炎 |
| CA2223225A1 (en) * | 1997-11-28 | 1999-05-28 | Canadian Red Cross Society | Method for inhibiting in vivo immune response |
| US7163686B1 (en) * | 1999-05-15 | 2007-01-16 | The Regents Of The University Of California | Protein A based binding domains with desirable activities |
| WO2000072882A1 (fr) * | 1999-06-01 | 2000-12-07 | Eisai Co., Ltd. | Agents prophylactiques du purpura thrombocytopenique idiopathique |
| JP3871503B2 (ja) | 1999-08-30 | 2007-01-24 | 日本たばこ産業株式会社 | 免疫性疾患治療剤 |
| ATE363290T1 (de) * | 1999-10-04 | 2007-06-15 | Novartis Vaccines & Diagnostic | Cd40 antagonist zur behandlung von psoriasis |
| EP1839674A1 (en) * | 1999-10-04 | 2007-10-03 | Novartis Vaccines and Diagnostics, Inc. | CD40 antagonist for treating psoriasis |
| DE60037822D1 (de) * | 1999-10-22 | 2008-03-06 | Biogen Idec Inc | Verwendung eines cd40:cd154 bindungs-unterbrechers zur behandlung immunologischer komplikationen des auges |
| GB0006398D0 (en) | 2000-03-16 | 2000-05-03 | Novartis Ag | Organic compounds |
| AU2001251612A1 (en) | 2000-04-14 | 2001-10-30 | Millennium Pharmaceuticals, Inc. | Roles of jak/stat family members in tolerance induction |
| US7560534B2 (en) | 2000-05-08 | 2009-07-14 | Celldex Research Corporation | Molecular conjugates comprising human monoclonal antibodies to dendritic cells |
| EP1284747A2 (en) | 2000-05-12 | 2003-02-26 | Beth Israel Deaconess Medical Center, Inc. | Compositions and methods for achieving immune suppression |
| JP2003535592A (ja) * | 2000-06-06 | 2003-12-02 | アイデック ファーマスーティカルズ コーポレイション | ヒトgp39に対する非アゴニスト抗体、含有する組成物、およびその治療的使用 |
| US20030133939A1 (en) | 2001-01-17 | 2003-07-17 | Genecraft, Inc. | Binding domain-immunoglobulin fusion proteins |
| US7754208B2 (en) | 2001-01-17 | 2010-07-13 | Trubion Pharmaceuticals, Inc. | Binding domain-immunoglobulin fusion proteins |
| AR039067A1 (es) | 2001-11-09 | 2005-02-09 | Pfizer Prod Inc | Anticuerpos para cd40 |
| WO2003086463A1 (en) * | 2002-04-03 | 2003-10-23 | Keio University | Remedies for pemphigus containing cd40l antagonist as the active ingredient |
| US9259459B2 (en) * | 2003-01-31 | 2016-02-16 | Celldex Therapeutics Inc. | Antibody vaccine conjugates and uses therefor |
| ATE552860T1 (de) * | 2003-01-31 | 2012-04-15 | Celldex Res Corp | Antikörper-vakzine-konjugate und ihre verwendungen |
| RU2240134C1 (ru) * | 2003-02-17 | 2004-11-20 | Козлов Владимир Александрович | Способ лечения больных сахарным диабетом |
| US20050079234A1 (en) * | 2003-08-27 | 2005-04-14 | Chiang Yang Chi | Compositions comprising herbs and method for immunomodulation |
| US7563443B2 (en) * | 2004-09-17 | 2009-07-21 | Domantis Limited | Monovalent anti-CD40L antibody polypeptides and compositions thereof |
| US20080279850A1 (en) * | 2005-07-25 | 2008-11-13 | Trubion Pharmaceuticals, Inc. | B-Cell Reduction Using CD37-Specific and CD20-Specific Binding Molecules |
| RU2423381C2 (ru) | 2005-07-25 | 2011-07-10 | Трабьон Фармасьютикалз, Инк. | Снижение количества в-клеток с использованием cd37-специфических и cd20-специфических связывающих молекул |
| NZ573646A (en) | 2006-06-12 | 2012-04-27 | Wyeth Llc | Single-chain multivalent binding proteins with effector function |
| CN101888856B (zh) | 2007-11-07 | 2014-08-27 | 塞尔德克斯医疗公司 | 结合人树突和上皮细胞205(dec-205)的抗体 |
| RU2531754C2 (ru) | 2008-04-11 | 2014-10-27 | ЭМЕРДЖЕНТ ПРОДАКТ ДИВЕЛОПМЕНТ СИЭТЛ,ЭлЭлСи,US | Связывающееся с cd37 иммунотерапевтическое средство и его комбинация с бифункциональным химиотерапевтическим средством |
| EP2310405A4 (en) * | 2008-07-11 | 2011-08-10 | Phylogica Ltd | PEPTIDE INHIBITORS OF SIGNALING USING CD40L AND USES THEREOF |
| AU2010222942B2 (en) | 2009-03-10 | 2013-01-10 | Baylor Research Institute | Anti-CD40 antibodies and uses thereof |
| DK2406289T3 (en) | 2009-03-10 | 2017-05-01 | Baylor Res Inst | ANTIGEN PRESENTING CELL TARGETED ANTIVIRUS VACCINES |
| US20130028897A1 (en) * | 2009-04-27 | 2013-01-31 | Ali Naji | Methods for reducing the level of alloantibodies in a subject |
| RU2439712C1 (ru) * | 2010-07-21 | 2012-01-10 | Сергей Валентинович Логвинов | Способ моделирования аутоиммунного оофорита |
| ES2791758T3 (es) * | 2011-12-22 | 2020-11-05 | Hoffmann La Roche | Organización de vectores de expresión, procedimientos de generación de células de producción novedosos y su uso para la producción recombinante de polipéptidos |
| PE20151893A1 (es) | 2013-03-14 | 2015-12-30 | Parkash Gill | Tratamiento del cancer usando anticuerpos que se unen a grp78 en la superficie celular |
| CN120939216A (zh) | 2014-01-13 | 2025-11-14 | 贝勒研究院 | 抗hpv和hpv相关的疾病的新疫苗 |
| CR20180097A (es) * | 2015-07-14 | 2018-05-25 | Immunext Inc | Anticuerpo anti-cd154 con caracteristicas de unión, funcionalidad y seguridad mejoradas y uso en inmunoterapia humana |
| UA123398C2 (uk) | 2015-08-05 | 2021-03-31 | Янссен Байотек, Інк. | Виділене антагоністичне антитіло, яке специфічно зв'язує cd154, та фармацевтична композиція, яка його містить |
| WO2017053469A2 (en) | 2015-09-21 | 2017-03-30 | Aptevo Research And Development Llc | Cd3 binding polypeptides |
| US10610585B2 (en) | 2017-09-26 | 2020-04-07 | Inserm (Institut National De La Sante Et De La Recherche Medicale) | Methods and compositions for treating and preventing HIV |
| WO2021146328A1 (en) | 2020-01-13 | 2021-07-22 | Aptevo Research And Development Llc | Formulations for protein therapeutics |
| BR112022013730A2 (pt) | 2020-01-13 | 2022-10-11 | Aptevo Res & Development Llc | Métodos e composições para prevenir a adsorção de proteínas terapêuticas aos componentes do sistema de distribuição de drogas |
| EP4341291A1 (en) | 2021-05-21 | 2024-03-27 | Aptevo Research and Development LLC | Dosing regimens for protein therapeutics |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8308235D0 (en) | 1983-03-25 | 1983-05-05 | Celltech Ltd | Polypeptides |
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5092585A (en) | 1987-06-11 | 1992-03-03 | Jones Arthur A | Apparatus for testing and/or exercising the cervical muscles of the human body |
| US4978745A (en) | 1987-11-23 | 1990-12-18 | Centocor, Inc. | Immunoreactive heterochain antibodies |
| US4975369A (en) | 1988-04-21 | 1990-12-04 | Eli Lilly And Company | Recombinant and chimeric KS1/4 antibodies directed against a human adenocarcinoma antigen |
| IL162181A (en) | 1988-12-28 | 2006-04-10 | Pdl Biopharma Inc | A method of producing humanized immunoglubulin, and polynucleotides encoding the same |
| EP0519596B1 (en) | 1991-05-17 | 2005-02-23 | Merck & Co. Inc. | A method for reducing the immunogenicity of antibody variable domains |
| US6136310A (en) * | 1991-07-25 | 2000-10-24 | Idec Pharmaceuticals Corporation | Recombinant anti-CD4 antibodies for human therapy |
| ES2198025T3 (es) | 1991-10-25 | 2004-01-16 | Immunex Corporation | Anticuerpos contra cd40-l. |
| US5474771A (en) * | 1991-11-15 | 1995-12-12 | The Trustees Of Columbia University In The City Of New York | Murine monoclonal antibody (5c8) recognizes a human glycoprotein on the surface of T-lymphocytes, compositions containing same |
| IL104684A0 (en) | 1992-02-14 | 1993-06-10 | Bristol Myers Squibb Co | The cd40cr receptor and ligands therefor |
| AU5098493A (en) | 1992-08-21 | 1994-03-15 | Schering Corporation | Cd40 ligand, anti cd40 antibodies, and soluble cd40 |
| US5540926A (en) | 1992-09-04 | 1996-07-30 | Bristol-Myers Squibb Company | Soluble and its use in B cell stimulation |
| NZ273208A (en) | 1993-09-02 | 2000-12-22 | Dartmouth College | Suppressing a humoral immune response against a thymus dependant (TD) antigen |
| ES2143553T3 (es) * | 1993-09-02 | 2000-05-16 | Dartmouth College | Anticuerpos anti-gp39 y sus utilizaciones. |
| US5683693A (en) | 1994-04-25 | 1997-11-04 | Trustees Of Dartmouth College | Method for inducing T cell unresponsiveness to a tissue or organ graft with anti-CD40 ligand antibody or soluble CD40 |
| US5876950A (en) | 1995-01-26 | 1999-03-02 | Bristol-Myers Squibb Company | Monoclonal antibodies specific for different epitopes of human GP39 and methods for their use in diagnosis and therapy |
| GB9507719D0 (en) * | 1995-04-13 | 1995-05-31 | Boc Group Plc | Machining of materials |
| US5833987A (en) * | 1995-06-07 | 1998-11-10 | Trustees Of Dartmouth College | Treatment of T cell mediated autoimmune disorders |
| US6440418B1 (en) * | 1995-11-07 | 2002-08-27 | Idec Pharmaceuticals Corporation | Methods of treating autoimmune diseases with gp39-specific antibodies |
| US6001358A (en) * | 1995-11-07 | 1999-12-14 | Idec Pharmaceuticals Corporation | Humanized antibodies to human gp39, compositions containing thereof |
| WO1998008541A1 (en) | 1996-08-30 | 1998-03-05 | Genzyme Corporation | Inhibition of primary and/or secondary immune response to repeat adenoviral vector administration using cd40l specific antibodies |
-
1997
- 1997-09-08 US US08/925,339 patent/US6440418B1/en not_active Expired - Fee Related
-
1998
- 1998-09-08 RU RU2000109255/14A patent/RU2207878C2/ru not_active IP Right Cessation
- 1998-09-08 CA CA002302752A patent/CA2302752A1/en not_active Abandoned
- 1998-09-08 JP JP2000510463A patent/JP2001515708A/ja not_active Abandoned
- 1998-09-08 CN CN98810897A patent/CN1278736A/zh active Pending
- 1998-09-08 EP EP98949305A patent/EP1011725A4/en not_active Withdrawn
- 1998-09-08 KR KR1020007002445A patent/KR100574591B1/ko not_active Expired - Fee Related
- 1998-09-08 IL IL13488898A patent/IL134888A0/xx unknown
- 1998-09-08 WO PCT/US1998/018163 patent/WO1999012566A1/en not_active Ceased
- 1998-09-08 AU AU95652/98A patent/AU740981B2/en not_active Ceased
-
2000
- 2000-03-03 NO NO20001104A patent/NO20001104L/no unknown
-
2002
- 2002-06-17 US US10/171,681 patent/US7122187B2/en not_active Expired - Fee Related
-
2006
- 2006-03-09 US US11/370,898 patent/US20060153837A1/en not_active Abandoned
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