JP2001512965A5 - - Google Patents

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Publication number
JP2001512965A5
JP2001512965A5 JP1998533032A JP53303298A JP2001512965A5 JP 2001512965 A5 JP2001512965 A5 JP 2001512965A5 JP 1998533032 A JP1998533032 A JP 1998533032A JP 53303298 A JP53303298 A JP 53303298A JP 2001512965 A5 JP2001512965 A5 JP 2001512965A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP1998533032A
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English (en)
Japanese (ja)
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JP4126097B2 (ja
JP2001512965A (ja
Filing date
Publication date
Priority claimed from US08/792,283 external-priority patent/US5804183A/en
Application filed filed Critical
Publication of JP2001512965A publication Critical patent/JP2001512965A/ja
Publication of JP2001512965A5 publication Critical patent/JP2001512965A5/ja
Application granted granted Critical
Publication of JP4126097B2 publication Critical patent/JP4126097B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP53303298A 1997-01-31 1998-01-27 Mycoplasma arthritidis由来アルギニンデイミナーゼ及びそれを含むポリマーコンジュゲート Expired - Fee Related JP4126097B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/792,283 US5804183A (en) 1997-01-31 1997-01-31 Arginine deminase derived from mycoplasma arthritidis and polymer conjugates containing the same
US08/792,283 1997-01-31
PCT/US1998/001635 WO1998033519A1 (en) 1997-01-31 1998-01-27 Arginine deiminase derived from mycoplasma arthritidis and polymer conjugates containing the same

Publications (3)

Publication Number Publication Date
JP2001512965A JP2001512965A (ja) 2001-08-28
JP2001512965A5 true JP2001512965A5 (https=) 2005-07-14
JP4126097B2 JP4126097B2 (ja) 2008-07-30

Family

ID=25156365

Family Applications (1)

Application Number Title Priority Date Filing Date
JP53303298A Expired - Fee Related JP4126097B2 (ja) 1997-01-31 1998-01-27 Mycoplasma arthritidis由来アルギニンデイミナーゼ及びそれを含むポリマーコンジュゲート

Country Status (9)

Country Link
US (3) US5804183A (https=)
EP (1) EP1011717B1 (https=)
JP (1) JP4126097B2 (https=)
AT (1) ATE314086T1 (https=)
AU (1) AU6047598A (https=)
DE (1) DE69832993T2 (https=)
DK (1) DK1011717T3 (https=)
ES (1) ES2255147T3 (https=)
WO (1) WO1998033519A1 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6635462B1 (en) * 1997-05-12 2003-10-21 Phoenix Pharmacologies, Inc. Mutated form of arginine deiminase
US6183738B1 (en) * 1997-05-12 2001-02-06 Phoenix Pharamacologics, Inc. Modified arginine deiminase
KR20040004449A (ko) * 2000-11-28 2004-01-13 휘닉스 파머컬러직스, 인크. 변형된 아르기닌 데이미나제
US6645739B2 (en) * 2001-07-26 2003-11-11 Phoenix Pharmacologies, Inc. Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
US8129330B2 (en) 2002-09-30 2012-03-06 Mountain View Pharmaceuticals, Inc. Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
US20040062748A1 (en) 2002-09-30 2004-04-01 Mountain View Pharmaceuticals, Inc. Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof
WO2004046309A2 (en) * 2002-11-18 2004-06-03 Phoenix Pharmacologics, Inc. Methods for inhibiting viral replication in vivo
FR2884717B1 (fr) * 2005-04-25 2009-07-03 Erytech Pharma Soc Par Actions Erythrocytes renfermant de l'arginine deiminase
US20080096819A1 (en) * 2006-05-02 2008-04-24 Allozyne, Inc. Amino acid substituted molecules
JP5313129B2 (ja) 2006-05-02 2013-10-09 アロザイン, インコーポレイテッド 非天然アミノ酸置換ポリペプチド
FR2919804B1 (fr) 2007-08-08 2010-08-27 Erytech Pharma Composition et vaccin therapeutique anti-tumoral
JP2009044997A (ja) * 2007-08-20 2009-03-05 Sony Corp ビリルビンオキシダーゼ(bod)の被覆方法
CA2707840A1 (en) 2007-08-20 2009-02-26 Allozyne, Inc. Amino acid substituted molecules
EP2295560A1 (en) 2009-09-14 2011-03-16 RWTH Aachen University Directed evolution of arginine deiminase for increased activity at physiological pH
US9255262B2 (en) * 2013-03-06 2016-02-09 Vision Global Holdings Ltd. Albumin-binding arginine deminase and the use thereof
USRE48805E1 (en) 2013-03-06 2021-11-02 Vision Global Holdings Ltd. Method for cancer targeting treatment and detection of arginine using albumin-binding arginine deiminase fusion protein
WO2014151982A2 (en) 2013-03-15 2014-09-25 Polaris Group Arginine deiminase with reduced cross-reactivity toward adi – peg 20 antibodies for cancer treatment
WO2015143006A1 (en) * 2014-03-18 2015-09-24 Tdw Group Engineered chimeric pegylated adi and methods of use
EP4104853B1 (en) 2014-09-16 2026-05-06 Polaris Group Arginine deiminase with reduced cross-reactivity toward adi - peg 20 antibodies for cancer treatment
EP3344575B1 (en) 2015-09-04 2020-04-15 SQZ Biotechnologies Company Intracellular delivery of biomolecules to cells comprising a cell wall
CA3023092A1 (en) 2016-05-03 2017-11-09 Sqz Biotechnologies Company Intracellular delivery of biomolecules to induce tolerance
CN119950689A (zh) 2016-07-05 2025-05-09 北极星药业集团股份有限公司 使用精氨酸耗竭剂的组合癌症免疫疗法
TWI784982B (zh) 2016-11-02 2022-12-01 開曼群島商北極星藥業集團股份有限公司 聚乙二醇化精胺酸脫亞胺酶之調配物
KR20220150408A (ko) 2016-11-14 2022-11-10 항저우 디에이씨 바이오테크 씨오, 엘티디 결합 링커, 그러한 결합 링커를 함유하는 세포 결합 분자-약물 결합체, 링커를 갖는 그러한 결합체의 제조 및 사용
WO2018183671A1 (en) 2017-03-29 2018-10-04 Tdw Group Protein conjugates
WO2019042628A1 (en) 2017-08-31 2019-03-07 Erytech Pharma ARGININE DEIMINASE ENCAPSULATED WITHIN ERYTHROCYTES AND THEIR USE IN THE TREATMENT OF CANCER AND ARGINASE-1 DEFICIENCY
EP3449935A1 (en) 2017-08-31 2019-03-06 Erytech Pharma Arginine deiminase encapsulated inside erythrocytes and their use in treating cancer and arginase-1 deficiency
KR20220053575A (ko) * 2019-08-01 2022-04-29 더 유니버시티 오브 노쓰 캐롤라이나 엣 채플 힐 항체 결합 및 중화 항체 억제를 위한 조성물 및 방법
CA3128035A1 (en) 2020-08-13 2022-02-13 Bioasis Technologies, Inc. Combination therapies for delivery across the blood brain barrier
EP4288445A1 (en) * 2021-02-03 2023-12-13 The University of North Carolina at Chapel Hill Protein m analogs and fusion proteins and their use for inhibiting antibody function
EP4426727A2 (en) 2021-11-03 2024-09-11 Hangzhou Dac Biotech Co., Ltd. Specific conjugation of an antibody

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4179337A (en) * 1973-07-20 1979-12-18 Davis Frank F Non-immunogenic polypeptides
JPH0253490A (ja) * 1988-08-16 1990-02-22 Agency Of Ind Science & Technol アルギニン・デイミナーゼ遺伝子
US5122614A (en) * 1989-04-19 1992-06-16 Enzon, Inc. Active carbonates of polyalkylene oxides for modification of polypeptides
JP2900279B2 (ja) * 1989-08-02 1999-06-02 株式会社ジャパンエナジー 新規なアルギニンデイミナーゼ、その製造法及び該酵素を有効成分とする制癌剤
JP3209338B2 (ja) * 1990-09-10 2001-09-17 株式会社ジャパンエナジー ポリエチレングリコール修飾アルギニンデイミナーゼおよびその製造法
US5372942A (en) * 1992-02-10 1994-12-13 Coriell Institute For Medical Research Protease K resistant arginine deiminase, its method of preparation and its use as an anti-neoplastic agent
US5349001A (en) * 1993-01-19 1994-09-20 Enzon, Inc. Cyclic imide thione activated polyalkylene oxides
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same

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