|
US7645743B2
(en)
*
|
1999-12-22 |
2010-01-12 |
Altermune, Llc |
Chemically programmable immunity
|
|
CA2328356A1
(en)
|
1999-12-22 |
2001-06-22 |
Itty Atcravi |
Recreational vehicles
|
|
JP3439195B2
(ja)
*
|
2000-02-17 |
2003-08-25 |
浜松ホトニクス株式会社 |
抗原の定量的検出方法
|
|
EP1517700B1
(en)
*
|
2002-04-22 |
2012-03-28 |
Recopharma AB |
Mucin fusion polypeptide vaccines, compositions and methods of use thereof
|
|
US8946387B2
(en)
*
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8187593B2
(en)
*
|
2002-08-14 |
2012-05-29 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8968730B2
(en)
*
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
JP4459810B2
(ja)
*
|
2002-08-14 |
2010-04-28 |
マクロジェニクス，インコーポレーテッド |
ＦｃγＲＩＩＢ特異的抗体とその利用法
|
|
US8044180B2
(en)
*
|
2002-08-14 |
2011-10-25 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US20050260213A1
(en)
*
|
2004-04-16 |
2005-11-24 |
Scott Koenig |
Fcgamma-RIIB-specific antibodies and methods of use thereof
|
|
US8530627B2
(en)
*
|
2002-08-14 |
2013-09-10 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
US8193318B2
(en)
*
|
2002-08-14 |
2012-06-05 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
|
DE10237317B4
(de)
*
|
2002-08-15 |
2010-04-08 |
3M Espe Ag |
Enzymhaltige Zusammensetzung, Verfahren zu deren Herstellung und deren Verwendung
|
|
EP1587540B1
(en)
|
2003-01-09 |
2021-09-15 |
MacroGenics, Inc. |
IDENTIFICATION AND ENGINEERING OF ANTIBODIES WITH VARIANT Fc REGIONS AND METHODS OF USING SAME
|
|
US7960512B2
(en)
*
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
BRPI0406724A
(pt)
|
2003-01-13 |
2005-12-20 |
Macrogenics Inc |
Proteìna de fusão dimérica, métodos de tratar, prevenir ou melhorar um ou mais sintomas de um distúrbio autoimune e um ou mais sintomas de púrpura trombocitopênica idiopática, composição farmacêutica, ácido nucleico, vetor, célula hospedeira, método de produzir recombinantemente o polipeptìdeo, polipeptìdeo isolado, fragmento de qualquer um dos polipeptìdeos, e, molécula de ácido nucleico isolada
|
|
WO2004069873A2
(en)
|
2003-02-06 |
2004-08-19 |
Tripep Ab |
Antigen/antibody or ligand/receptor glycosylated specificity exchangers
|
|
WO2005020841A2
(en)
*
|
2003-08-25 |
2005-03-10 |
Sarnoff Corporation |
Monitoring using signals detected from auditory canal
|
|
AU2005214361B2
(en)
*
|
2004-02-13 |
2011-03-24 |
Immunomedics, Inc. |
Fusion proteins containing recombinant cytotoxic RNAses
|
|
CA2565874C
(en)
|
2004-05-10 |
2017-10-03 |
Macrogenics, Inc. |
Humanized fc.gamma.riib-specific antibodies and methods of use thereof
|
|
EP1600141B1
(en)
*
|
2004-05-24 |
2013-04-17 |
3M Deutschland GmbH |
Collagenolytic active enzyme containing compositions for the treatment of dental caries
|
|
DK2412728T3
(en)
|
2004-08-03 |
2015-04-07 |
Innate Pharma |
Therapeutic compositions for cancer, that target 4Ig-B7-H3
|
|
AU2005335714B2
(en)
|
2004-11-10 |
2012-07-26 |
Macrogenics, Inc. |
Engineering Fc antibody regions to confer effector function
|
|
EP3332808B1
(en)
|
2005-03-03 |
2020-09-09 |
Immunomedics Inc. |
Humanized l243 antibodies
|
|
WO2012018687A1
(en)
|
2010-08-02 |
2012-02-09 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
AU2006236439B2
(en)
|
2005-04-15 |
2012-05-03 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
FR2886298A1
(fr)
*
|
2005-05-24 |
2006-12-01 |
Ifremer |
Anticorps ou fragment d'anticorps couple a un agent immunogene
|
|
PL1919503T3
(pl)
|
2005-08-10 |
2015-04-30 |
Macrogenics Inc |
Identyfikacja i inżynieria przeciwciał ze zmiennymi regionami FC oraz sposoby ich stosowania
|
|
EP1754464A1
(en)
*
|
2005-08-17 |
2007-02-21 |
3M Innovative Properties Company |
Enzyme comprising dental composition
|
|
EP2674440B1
(en)
|
2005-12-16 |
2019-07-03 |
IBC Pharmaceuticals, Inc. |
Multivalent immunoglobulin-based bioactive assemblies
|
|
JP2009529331A
(ja)
*
|
2006-03-10 |
2009-08-20 |
マクロジェニクス，インコーポレーテッド |
変異型重鎖を有する抗体の同定および工学的改変ならびにその使用方法
|
|
CA2660592C
(en)
|
2006-05-26 |
2016-07-12 |
Macrogenics, Inc. |
Humanized fc.gamma.riib-specific antibodies and methods of use thereof
|
|
EP2505209A1
(en)
*
|
2006-06-26 |
2012-10-03 |
MacroGenics, Inc. |
Fcgamma-RIIB-specific antibodies and methods of the use thereof
|
|
CA2656224C
(en)
|
2006-06-26 |
2018-01-09 |
Macrogenics, Inc. |
Combination of fc.gamma.riib antibodies and cd20-specific antibodies and methods of use thereof
|
|
US20080112961A1
(en)
*
|
2006-10-09 |
2008-05-15 |
Macrogenics, Inc. |
Identification and Engineering of Antibodies with Variant Fc Regions and Methods of Using Same
|
|
US8652466B2
(en)
*
|
2006-12-08 |
2014-02-18 |
Macrogenics, Inc. |
Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
|
|
CA2915168C
(en)
*
|
2007-01-30 |
2017-05-23 |
Epivax, Inc. |
Regulatory t cell epitopes, compositions and uses thereof
|
|
AU2014201846B2
(en)
*
|
2007-01-30 |
2016-07-07 |
Epivax, Inc. |
Regulatory t cell epitopes, compositions and uses thereof
|
|
AU2016203577B2
(en)
*
|
2007-01-30 |
2017-12-21 |
Epivax, Inc. |
Regulatory T cell epitopes, compositions and uses thereof
|
|
MX2009013816A
(es)
|
2007-06-21 |
2010-02-24 |
Macrogenics Inc |
Diacuerpos covalentes y usos de los mismos.
|
|
SG189730A1
(en)
|
2008-04-02 |
2013-05-31 |
Macrogenics Inc |
Her2/neu-specific antibodies and methods of using same
|
|
JP5785490B2
(ja)
|
2008-04-02 |
2015-09-30 |
マクロジェニクス，インコーポレーテッド |
Ｂｃｒ複合体特異的抗体およびその使用方法
|
|
ES2675730T3
(es)
*
|
2008-06-04 |
2018-07-12 |
Macrogenics, Inc. |
Anticuerpos con unión alterada a FcRn y métodos de uso de los mismos
|
|
CN102369021B
(zh)
|
2008-12-19 |
2016-09-07 |
宏观基因有限公司 |
共价双抗体及其用途
|
|
JP5757483B2
(ja)
*
|
2009-04-30 |
2015-07-29 |
国立大学法人広島大学 |
抗体性拒絶反応抑制剤
|
|
BRPI1011269A2
(pt)
*
|
2009-05-05 |
2016-09-27 |
Altermune Technologies Llc |
imunidade quimicamente programável
|
|
CN102482701B
(zh)
|
2009-09-16 |
2015-05-13 |
免疫医疗公司 |
I类抗-cea抗体及其使用
|
|
KR101808602B1
(ko)
|
2009-10-07 |
2017-12-13 |
마크로제닉스, 인크. |
푸코실화 정도의 변경으로 인해 개선된 이펙터 기능을 나타내는 Ｆｃ 영역-함유 폴리펩티드, 그것의 사용 방법
|
|
CA2782194C
(en)
|
2009-12-02 |
2018-01-16 |
Immunomedics, Inc. |
Combination of radiolabelled antibodies (rait) and antibody-drug conjugates (adc) for treatment of pancreatic cancer
|
|
US9150656B2
(en)
|
2010-03-04 |
2015-10-06 |
Macrogenics, Inc. |
Antibodies reactive with B7-H3, immunologically active fragments thereof and uses thereof
|
|
PH12012501751A1
(en)
|
2010-03-04 |
2012-11-12 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
|
AU2011268110B2
(en)
|
2010-06-19 |
2016-05-19 |
Memorial Sloan-Kettering Cancer Center |
Anti-GD2 antibodies
|
|
US20120258496A1
(en)
*
|
2010-09-27 |
2012-10-11 |
Boehringer Ingelheim International Gmbh |
Production of low fucose antibodies in h4-ii-e rat cells
|
|
JP6024025B2
(ja)
|
2011-05-02 |
2016-11-09 |
イミューノメディクス、インコーポレイテッドＩｍｍｕｎｏｍｅｄｉｃｓ， Ｉｎｃ． |
少容量投与用のアロタイプ選択抗体の限外濾過濃縮
|
|
WO2012162068A2
(en)
|
2011-05-21 |
2012-11-29 |
Macrogenics, Inc. |
Deimmunized serum-binding domains and their use for extending serum half-life
|
|
KR101566538B1
(ko)
|
2012-06-08 |
2015-11-05 |
국립암센터 |
신규한 Ｔｈ17 세포 전환용 에피토프 및 이의 용도
|
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
|
ES2882183T3
(es)
|
2013-03-14 |
2021-12-01 |
Univ Duke |
Moléculas biespecíficas que son inmunorreactivas con células efectoras inmunitarias que expresan un receptor activador
|
|
RU2680267C2
(ru)
|
2013-03-15 |
2019-02-19 |
Мемориал Слоан Кеттеринг Кэнсер Сентер |
Высокоаффинные антитела к gd2
|
|
AU2015217278B2
(en)
|
2014-02-14 |
2020-03-19 |
Macrogenics, Inc. |
Improved methods for the treatment of vascularizing cancers
|
|
US9139649B2
(en)
|
2014-02-25 |
2015-09-22 |
Immunomedics, Inc. |
Humanized anti-CD22 antibody
|
|
NZ726520A
(en)
|
2014-05-29 |
2018-12-21 |
Macrogenics Inc |
Tri-specific binding molecules that specifically bind to multiple cancer antigens and methods of use thereof
|
|
WO2018140026A1
(en)
|
2017-01-27 |
2018-08-02 |
Memorial Sloan Kettering Cancer Center |
Bispecific her2 and cd3 binding molecules
|
|
CN107108721B
(zh)
|
2014-09-29 |
2021-09-07 |
杜克大学 |
包含hiv-1包膜靶向臂的双特异性分子
|
|
AU2015328370B2
(en)
|
2014-10-07 |
2021-08-05 |
Immunomedics, Inc. |
Neoadjuvant use of antibody-drug conjugates
|
|
AU2015380455A1
(en)
|
2015-01-26 |
2017-08-03 |
Macrogenics, Inc. |
Multivalent molecules comprising DR5-binding domains
|
|
EP3256164B1
(en)
|
2015-02-09 |
2020-03-25 |
Memorial Sloan Kettering Cancer Center |
Multi-specific antibodies with affinity for human a33 antigen and dota metal complex
|
|
CA2981543A1
(en)
|
2015-04-22 |
2016-10-27 |
Immunomedics, Inc. |
Isolation, detection, diagnosis and/or characterization of circulating trop-2-positive cancer cells
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
EP3307319A4
(en)
|
2015-06-09 |
2019-05-22 |
Memorial Sloan Kettering Cancer Center |
T CELL RECEPTOR-SIMILAR ANTIBODIES SPECIFIC TO PEPTID OF THE LATENT EBV MEMBRANE PROTEIN 2A PRESENTED BY HUMAN HLA
|
|
TWI870335B
(zh)
|
2015-06-12 |
2025-01-21 |
美商宏觀基因股份有限公司 |
變異的嵌合4d5抗體及其與抗pd-1抗體聯合用於治療癌症的應用
|
|
PL3316885T3
(pl)
|
2015-07-01 |
2021-12-06 |
Immunomedics, Inc. |
Immunokoniugaty przeciwciało-sn-38 z linkerem cl2a
|
|
CN116333138A
(zh)
|
2015-07-30 |
2023-06-27 |
宏观基因有限公司 |
Pd-1结合分子和其使用方法
|
|
TW202208440A
(zh)
|
2015-12-14 |
2022-03-01 |
美商宏觀基因股份有限公司 |
對於pd-1和ctla-4具有免疫反應性的雙特異性分子及其使用方法
|
|
MY198114A
(en)
|
2016-04-15 |
2023-08-04 |
Macrogenics Inc |
Novel b7-h3-binding molecules, antibody drug conjugates thereof and methods of use thereof
|
|
AU2018206015B2
(en)
|
2017-01-06 |
2019-05-30 |
Eutilex Co., Ltd. |
Anti-human 4-1 BB antibodies and use thereof
|
|
CA3052740A1
(en)
|
2017-02-10 |
2018-08-16 |
Eutilex Co., Ltd. |
Ifn-.gamma.-inducible regulatory t cell convertible anti-cancer (irtca) antibody and uses thereof
|
|
GB201705686D0
(en)
*
|
2017-04-07 |
2017-05-24 |
Centauri Therapeutics Ltd |
Novel compounds and therapeutic uses thereof
|
|
CN112088169A
(zh)
|
2018-03-12 |
2020-12-15 |
纪念斯隆凯特琳癌症中心 |
双特异性结合剂及其用途
|
|
GB201816553D0
(en)
|
2018-10-10 |
2018-11-28 |
Centauri Therapeutics Ltd |
Novel compounds and therapeutic uses thereof
|
|
KR20210152472A
(ko)
|
2019-03-11 |
2021-12-15 |
메모리얼 슬로안 케터링 캔서 센터 |
Cd22 항체 및 이를 사용하는 방법
|
|
US20240115721A1
(en)
|
2021-01-13 |
2024-04-11 |
Memorial Sloan Kettering Cancer Center |
Anti-dll3 antibody-drug conjugate
|
|
CA3204628A1
(en)
|
2021-01-13 |
2022-07-21 |
John T. POIRIER |
Antibody-pyrrolobenzodiazepine derivative conjugate
|