JP2001510819A - タモキシフェンおよびその同族体 - Google Patents

タモキシフェンおよびその同族体

Info

Publication number
JP2001510819A
JP2001510819A JP2000504090A JP2000504090A JP2001510819A JP 2001510819 A JP2001510819 A JP 2001510819A JP 2000504090 A JP2000504090 A JP 2000504090A JP 2000504090 A JP2000504090 A JP 2000504090A JP 2001510819 A JP2001510819 A JP 2001510819A
Authority
JP
Japan
Prior art keywords
solvent
tamoxifen
isomer
derivative
precursor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2000504090A
Other languages
English (en)
Japanese (ja)
Inventor
ジョン・ダブル
デレク・メイトランド
イオアナ・ポパ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Bradford
Original Assignee
University of Bradford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Bradford filed Critical University of Bradford
Publication of JP2001510819A publication Critical patent/JP2001510819A/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2000504090A 1997-07-23 1998-07-21 タモキシフェンおよびその同族体 Withdrawn JP2001510819A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9715479.3 1997-07-23
GBGB9715479.3A GB9715479D0 (en) 1997-07-23 1997-07-23 Tamoxifen and analogues thereof
PCT/GB1998/002171 WO1999005088A1 (en) 1997-07-23 1998-07-21 Tamoxifen and analogues thereof

Publications (1)

Publication Number Publication Date
JP2001510819A true JP2001510819A (ja) 2001-08-07

Family

ID=10816289

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000504090A Withdrawn JP2001510819A (ja) 1997-07-23 1998-07-21 タモキシフェンおよびその同族体

Country Status (8)

Country Link
EP (1) EP0998447A1 (de)
JP (1) JP2001510819A (de)
AU (1) AU8452998A (de)
CA (1) CA2297246A1 (de)
GB (2) GB9715479D0 (de)
HU (1) HUP0002807A3 (de)
NO (1) NO316376B1 (de)
WO (1) WO1999005088A1 (de)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (de) * 1962-09-13
EP0127128B1 (de) * 1983-05-24 1987-02-25 Bristol-Myers Company Verfahren zur Umwandlung von 1,2-Diphenyl-1-[4-(2-dimethylamino-ethoxy)-phenyl]-1-buten-E-Isomeren zu Tamoxifen-Hydrochlorid
GB2160202B (en) * 1984-06-12 1987-12-02 Nat Res Dev Preparation of tamoxifen
ATE80152T1 (de) * 1987-04-21 1992-09-15 Heumann Pharma Gmbh & Co Stabile loesungsmitteladdukte von z-1-(p-betadimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl) 2-phenylbut-1-en.
DE3736682A1 (de) * 1987-10-29 1989-05-11 Klinge Co Chem Pharm Fab Verfahren zur herstellung von trans-1,1,2-triphenyl-but-1-en-derivaten
CA2150230C (en) * 1993-10-25 1998-10-27 Fumihiko Shinozaki Process for producing acid-addition salt of z-isomer of triphenylethylene compound
US5693863A (en) * 1994-01-03 1997-12-02 Klinge Pharma Gmbh Method for the production of E-1- 4'- (2- Dimethylaminoethoxy) - Phenyl!-1-(3-Hydroxyphenyl) -2-Phenyl-1-Butene
GB9601167D0 (en) * 1996-01-20 1996-03-20 Univ Bradford Tamoxifen and analogues thereof

Also Published As

Publication number Publication date
WO1999005088A1 (en) 1999-02-04
NO20000329L (no) 2000-03-23
HUP0002807A1 (hu) 2001-11-28
AU8452998A (en) 1999-02-16
GB9715479D0 (en) 1997-10-01
GB2327673B (en) 2002-03-27
CA2297246A1 (en) 1999-02-04
GB9815904D0 (en) 1998-09-16
HUP0002807A3 (en) 2002-01-28
GB2327673A (en) 1999-02-03
EP0998447A1 (de) 2000-05-10
NO316376B1 (no) 2004-01-19
NO20000329D0 (no) 2000-01-21

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Legal Events

Date Code Title Description
A621 Written request for application examination

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Effective date: 20050721

A761 Written withdrawal of application

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Effective date: 20051101