GB2327673B - Tamoxifen and analogues thereof - Google Patents

Tamoxifen and analogues thereof

Info

Publication number
GB2327673B
GB2327673B GB9815904A GB9815904A GB2327673B GB 2327673 B GB2327673 B GB 2327673B GB 9815904 A GB9815904 A GB 9815904A GB 9815904 A GB9815904 A GB 9815904A GB 2327673 B GB2327673 B GB 2327673B
Authority
GB
United Kingdom
Prior art keywords
tamoxifen
analogues
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
GB9815904A
Other versions
GB9815904D0 (en
GB2327673A (en
Inventor
John Double
Derek Maitland
Ioana Popa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Generic Biologicals Ltd
University of Bradford
Original Assignee
Generic Biologicals Ltd
University of Bradford
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Generic Biologicals Ltd, University of Bradford filed Critical Generic Biologicals Ltd
Publication of GB9815904D0 publication Critical patent/GB9815904D0/en
Publication of GB2327673A publication Critical patent/GB2327673A/en
Application granted granted Critical
Publication of GB2327673B publication Critical patent/GB2327673B/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
GB9815904A 1997-07-23 1998-07-21 Tamoxifen and analogues thereof Expired - Fee Related GB2327673B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9715479.3A GB9715479D0 (en) 1997-07-23 1997-07-23 Tamoxifen and analogues thereof

Publications (3)

Publication Number Publication Date
GB9815904D0 GB9815904D0 (en) 1998-09-16
GB2327673A GB2327673A (en) 1999-02-03
GB2327673B true GB2327673B (en) 2002-03-27

Family

ID=10816289

Family Applications (2)

Application Number Title Priority Date Filing Date
GBGB9715479.3A Pending GB9715479D0 (en) 1997-07-23 1997-07-23 Tamoxifen and analogues thereof
GB9815904A Expired - Fee Related GB2327673B (en) 1997-07-23 1998-07-21 Tamoxifen and analogues thereof

Family Applications Before (1)

Application Number Title Priority Date Filing Date
GBGB9715479.3A Pending GB9715479D0 (en) 1997-07-23 1997-07-23 Tamoxifen and analogues thereof

Country Status (8)

Country Link
EP (1) EP0998447A1 (en)
JP (1) JP2001510819A (en)
AU (1) AU8452998A (en)
CA (1) CA2297246A1 (en)
GB (2) GB9715479D0 (en)
HU (1) HUP0002807A3 (en)
NO (1) NO316376B1 (en)
WO (1) WO1999005088A1 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0127128A1 (en) * 1983-05-24 1984-12-05 Bristol-Myers Company Process for the conversion of the E isomer of 1,2-diphenyl-1-(4-(2-dimethylaminoethoxy)-phenyl)-1-butene to tamoxifen HCl
EP0287690A1 (en) * 1987-04-21 1988-10-26 HEUMANN PHARMA GMBH & CO Stable solvent adducts of Z-1-(p-beta-dimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenylbut-1-ene
WO1995011879A1 (en) * 1993-10-25 1995-05-04 Taiho Pharmaceutical Co., Ltd. Process for producing acid-addition salt of z-isomer of triphenylethylene compound
WO1995018786A1 (en) * 1994-01-03 1995-07-13 Klinge Pharma Gmbh Method for the production of e-1-[4'-(2-dimethylaminoethoxy)-phenyl]-1-(3'-hydroxyphenyl)-2-phenyl-1-butene
GB2309224A (en) * 1996-01-20 1997-07-23 Univ Bradford Isomers of tamoxifen and analogues thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE637389A (en) * 1962-09-13
GB2160202B (en) * 1984-06-12 1987-12-02 Nat Res Dev Preparation of tamoxifen
DE3736682A1 (en) * 1987-10-29 1989-05-11 Klinge Co Chem Pharm Fab METHOD FOR PRODUCING TRANS-1,1,2-TRIPHENYL-BUT-1-EN DERIVATIVES

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0127128A1 (en) * 1983-05-24 1984-12-05 Bristol-Myers Company Process for the conversion of the E isomer of 1,2-diphenyl-1-(4-(2-dimethylaminoethoxy)-phenyl)-1-butene to tamoxifen HCl
EP0287690A1 (en) * 1987-04-21 1988-10-26 HEUMANN PHARMA GMBH & CO Stable solvent adducts of Z-1-(p-beta-dimethylamino-ethoxyphenyl)-1-(p-hydroxyphenyl)-2-phenylbut-1-ene
WO1995011879A1 (en) * 1993-10-25 1995-05-04 Taiho Pharmaceutical Co., Ltd. Process for producing acid-addition salt of z-isomer of triphenylethylene compound
WO1995018786A1 (en) * 1994-01-03 1995-07-13 Klinge Pharma Gmbh Method for the production of e-1-[4'-(2-dimethylaminoethoxy)-phenyl]-1-(3'-hydroxyphenyl)-2-phenyl-1-butene
GB2309224A (en) * 1996-01-20 1997-07-23 Univ Bradford Isomers of tamoxifen and analogues thereof

Also Published As

Publication number Publication date
WO1999005088A1 (en) 1999-02-04
NO20000329L (en) 2000-03-23
HUP0002807A1 (en) 2001-11-28
AU8452998A (en) 1999-02-16
JP2001510819A (en) 2001-08-07
GB9715479D0 (en) 1997-10-01
CA2297246A1 (en) 1999-02-04
GB9815904D0 (en) 1998-09-16
HUP0002807A3 (en) 2002-01-28
GB2327673A (en) 1999-02-03
EP0998447A1 (en) 2000-05-10
NO316376B1 (en) 2004-01-19
NO20000329D0 (en) 2000-01-21

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee

Effective date: 20060721