JP2001507676A5 - - Google Patents

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Publication number
JP2001507676A5
JP2001507676A5 JP1998522179A JP52217998A JP2001507676A5 JP 2001507676 A5 JP2001507676 A5 JP 2001507676A5 JP 1998522179 A JP1998522179 A JP 1998522179A JP 52217998 A JP52217998 A JP 52217998A JP 2001507676 A5 JP2001507676 A5 JP 2001507676A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP1998522179A
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English (en)
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JP4264137B2 (ja
JP2001507676A (ja
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Priority claimed from IT96MI002368A external-priority patent/IT1295694B1/it
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Publication of JP2001507676A publication Critical patent/JP2001507676A/ja
Publication of JP2001507676A5 publication Critical patent/JP2001507676A5/ja
Application granted granted Critical
Publication of JP4264137B2 publication Critical patent/JP4264137B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Description

Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
Figure 2001507676
JP52217998A 1996-11-14 1997-11-12 抗血栓性有機硝酸塩 Expired - Fee Related JP4264137B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT96MI002368A IT1295694B1 (it) 1996-11-14 1996-11-14 Nitrossi derivati per la preparazione di medicamenti ad attivita antitrombinica
IT96A002368 1996-11-14
PCT/EP1997/006311 WO1998021193A1 (en) 1996-11-14 1997-11-12 Antithrombotic organic nitrates

Publications (3)

Publication Number Publication Date
JP2001507676A JP2001507676A (ja) 2001-06-12
JP2001507676A5 true JP2001507676A5 (ja) 2005-07-14
JP4264137B2 JP4264137B2 (ja) 2009-05-13

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP52217998A Expired - Fee Related JP4264137B2 (ja) 1996-11-14 1997-11-12 抗血栓性有機硝酸塩

Country Status (18)

Country Link
US (1) US6242432B1 (ja)
EP (1) EP0941218B1 (ja)
JP (1) JP4264137B2 (ja)
KR (1) KR100504122B1 (ja)
CN (1) CN1094931C (ja)
AT (1) ATE226199T1 (ja)
AU (1) AU729423B2 (ja)
BR (1) BR9712959B1 (ja)
CA (1) CA2272063C (ja)
DE (1) DE69716461T2 (ja)
DK (1) DK0941218T3 (ja)
ES (1) ES2186013T3 (ja)
HU (1) HUP0000667A3 (ja)
IL (1) IL129768A (ja)
IT (1) IT1295694B1 (ja)
PT (1) PT941218E (ja)
RU (1) RU2190594C2 (ja)
WO (1) WO1998021193A1 (ja)

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DE60131537T2 (de) 2000-06-22 2008-10-23 Nitromed, Inc., Lexington Nitrosierte und nitrosylierte taxane, zubereitungen und methoden der verwendung
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JP2004528337A (ja) 2001-05-02 2004-09-16 ニトロメド インコーポレーテッド ニトロソ化およびニトロシル化ネビボロール、ならびにその代謝産物、組成物、および使用方法
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US7968605B2 (en) * 2002-02-04 2011-06-28 ALFAMA—Investigação e Desenvolvimento de Produtos Farmacêuticos, Lda. Methods for treating inflammatory disease by administering aldehydes and derivatives thereof
AU2003248642A1 (en) 2002-06-11 2003-12-22 Nitromed, Inc. Nitrosated and/or nitrosylated cyclooxygenase-2 selective inhibitors, compositions and methods of use
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US7166638B2 (en) 2003-05-27 2007-01-23 Nicox S.A. Statin derivatives
US7169805B2 (en) * 2003-05-28 2007-01-30 Nicox S.A. Captopril derivatives
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US20070010571A1 (en) * 2003-08-20 2007-01-11 Nitromed, Inc. Nitrosated and nitrosylated cardiovascular compounds, compositions and methods of use
DE602004005748T2 (de) * 2003-12-02 2007-12-27 Nicox S.A., Sophia Antipolis Nitrooxy-derivate von carvedilol und anderen betablockern als antihypertensiva
EP1748994B1 (en) * 2003-12-02 2009-02-18 NicOx S.A. Nitrooxyderivatives of antihypertensive drugs
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WO2006052899A2 (en) * 2004-11-08 2006-05-18 Nitromed, Inc. Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders
WO2006078995A1 (en) * 2005-01-21 2006-07-27 Nitromed, Inc. Cardiovascular compounds comprising heterocyclic nitric oxide donor group compositions and methods of use
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EP2699242B1 (en) 2011-04-19 2017-11-01 Alfama, Inc. Carbon monoxide releasing molecules and uses thereof
EP2734235B1 (en) 2011-07-21 2017-03-22 Alfama, Inc. Ruthenium carbon monoxide releasing molecules and uses thereof
CA2897571C (en) 2013-01-21 2018-12-18 Apparao Satyam Nitric oxide releasing prodrugs of therapeutic agents containing at least one carboxylic acid group
BR112019009330A2 (pt) 2016-11-08 2019-07-30 Bausch & Lomb composto
AU2020300002A1 (en) 2019-07-01 2022-02-24 Tonix Pharma Limited Anti-CD154 antibodies and uses thereof
CN116963750A (zh) 2021-01-06 2023-10-27 通尼克斯制药有限公司 用经修饰的抗-cd154抗体诱导免疫耐受的方法

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Publication number Priority date Publication date Assignee Title
IT1256345B (it) 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione
IT1256450B (it) 1992-11-26 1995-12-05 Soldato Piero Del Esteri nitrici con attivita' farmacologica e procedimento per la loro preparazione
ES2065291B1 (es) * 1993-07-30 1995-10-01 Prodesfarma Sa "nitrato esteres de 1-ariloxi-3-alquilamino-2-propanoles, utilizacion y composicion farmaceutica correspondiente"
DE69412109T2 (de) 1993-10-06 1999-01-21 Nicox S.A., Paris Salzetersaüreester mit entzündungshemmender und/oder schmerzlindernder wirkung und verfahren zu deren herstellung
DK0759899T3 (da) 1994-05-10 1999-12-20 Nicox Sa Nitroforbindelser og sammensætninger deraf med antiinflammatoriske, analgetiske og antitrombotiske aktiviteter
WO1997031896A1 (fr) * 1996-03-01 1997-09-04 Sankyo Company, Limited Derives de thiazolidine

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