JP2001505883A5 - - Google Patents

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Publication number
JP2001505883A5
JP2001505883A5 JP1998525818A JP52581898A JP2001505883A5 JP 2001505883 A5 JP2001505883 A5 JP 2001505883A5 JP 1998525818 A JP1998525818 A JP 1998525818A JP 52581898 A JP52581898 A JP 52581898A JP 2001505883 A5 JP2001505883 A5 JP 2001505883A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998525818A
Other languages
English (en)
Japanese (ja)
Other versions
JP4274584B2 (ja
JP2001505883A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/022289 external-priority patent/WO1998024805A1/en
Publication of JP2001505883A publication Critical patent/JP2001505883A/ja
Publication of JP2001505883A5 publication Critical patent/JP2001505883A5/ja
Application granted granted Critical
Publication of JP4274584B2 publication Critical patent/JP4274584B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP52581898A 1996-12-06 1997-12-05 インターロイキン−1β変換酵素のインヒビター Expired - Lifetime JP4274584B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3279296P 1996-12-06 1996-12-06
US60/032,792 1996-12-06
US4266097P 1997-04-04 1997-04-04
US60/042,660 1997-04-04
US5300197P 1997-06-26 1997-06-26
US60/053,001 1997-06-26
PCT/US1997/022289 WO1998024805A1 (en) 1996-12-06 1997-12-05 INHIBITORS OF INTERLEUKIN-1β CONVERTING ENZYME

Publications (3)

Publication Number Publication Date
JP2001505883A JP2001505883A (ja) 2001-05-08
JP2001505883A5 true JP2001505883A5 (enExample) 2005-08-11
JP4274584B2 JP4274584B2 (ja) 2009-06-10

Family

ID=27364225

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52581898A Expired - Lifetime JP4274584B2 (ja) 1996-12-06 1997-12-05 インターロイキン−1β変換酵素のインヒビター

Country Status (10)

Country Link
US (3) US6329365B1 (enExample)
EP (1) EP0944645B1 (enExample)
JP (1) JP4274584B2 (enExample)
AT (1) ATE290545T1 (enExample)
AU (1) AU5896098A (enExample)
CA (1) CA2274249A1 (enExample)
DE (1) DE69732712T2 (enExample)
ES (1) ES2239788T3 (enExample)
PT (1) PT944645E (enExample)
WO (1) WO1998024805A1 (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4274584B2 (ja) * 1996-12-06 2009-06-10 バーテックス ファーマシューティカルズ インコーポレイテッド インターロイキン−1β変換酵素のインヒビター
US20010049381A1 (en) 1997-06-04 2001-12-06 Gpl Nil Holdings, Inc., Pyrrolidine derivative hair growth compositions and uses
US5945441A (en) 1997-06-04 1999-08-31 Gpi Nil Holdings, Inc. Pyrrolidine carboxylate hair revitalizing agents
US6184210B1 (en) * 1997-10-10 2001-02-06 Cytovia, Inc. Dipeptide apoptosis inhibitors and the use thereof
JP2001522800A (ja) 1997-11-10 2001-11-20 ブリストル−マイヤーズ スクイブ カンパニー ベンゾチアゾールたんぱくチロシン・キナーゼ抑制剤
US6331537B1 (en) 1998-06-03 2001-12-18 Gpi Nil Holdings, Inc. Carboxylic acids and carboxylic acid isosteres of N-heterocyclic compounds
SK18302000A3 (sk) 1998-06-03 2001-06-11 Gpi Nil Holdings, Inc. N-viazané sulfónamidy n-heterocyklických karboxylových kyselín a izosterov karboxylových kyselín, farmaceutický prostriedok s ich obsahom a ich použitie
US6395758B1 (en) 1998-08-14 2002-05-28 Gpi Nil Holdings, Inc. Small molecule carbamates or ureas for vision and memory disorders
US7338976B1 (en) 1998-08-14 2008-03-04 Gpi Nil Holdings, Inc. Heterocyclic esters or amides for vision and memory disorders
FR2782997A1 (fr) * 1998-09-08 2000-03-10 Hoechst Marion Roussel Inc Nouveaux derives de la benzodiazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicaments et compositions pharmaceutiques les renfermant
US6462072B1 (en) 1998-09-21 2002-10-08 Gpi Nil Holdings, Inc. Cyclic ester or amide derivatives
US7253169B2 (en) 1999-11-12 2007-08-07 Gliamed, Inc. Aza compounds, pharmaceutical compositions and methods of use
DE60026568D1 (de) 1999-12-21 2006-05-04 Mgi Gp Inc Hydantoin derivate, pharmazeutische zusammensetzungen und verfahren zu ihrer verwendung
WO2002066063A1 (en) * 2001-02-23 2002-08-29 Nippon Organon K.K. Remedies for metabolic bone diseases
DE10129715A1 (de) * 2001-06-22 2003-01-02 Bayer Ag Thiazolylamide
US7001899B2 (en) * 2002-06-10 2006-02-21 The Procter & Gamble Company Interleukin converting enzyme inhibitors
CA2490401A1 (en) 2002-06-28 2004-01-08 Life Technologies Corporation Compositions and methods for restoring immune repertoire in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
US7060698B2 (en) * 2003-05-19 2006-06-13 Hoffmann-La Roche Inc. Benzoxazepinone derivatives
US20060128696A1 (en) * 2004-05-15 2006-06-15 Annamaria Vezzani Treating seizures using ice inhibitors
JP4980358B2 (ja) * 2005-09-19 2012-07-18 アロー セラピューティクス リミテッド C型肝炎感染症を治療するためのベンゾジアゼピン誘導体
JP5806670B2 (ja) 2009-09-16 2015-11-10 セルジーン アビロミクス リサーチ, インコーポレイテッド プロテインキナーゼコンジュゲート及びインヒビター
CN102812167A (zh) 2009-12-30 2012-12-05 阿维拉制药公司 蛋白的配体-介导的共价修饰
US9956260B1 (en) 2011-07-22 2018-05-01 The J. David Gladstone Institutes Treatment of HIV-1 infection and AIDS
WO2020110143A1 (en) 2018-11-26 2020-06-04 Rai Balwant Methods, systems, and a kit for diagnosis, detection, monitoring and treatment of traumatic brain injury

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4970207A (en) * 1988-07-07 1990-11-13 Fujisawa Pharmaceutical Company, Ltd. Benzodiazepine derivatives
CA2160786A1 (en) * 1993-05-14 1994-11-24 James C. Marsters, Jr. Ras farnesyl transferase inhibitors
US5580979A (en) * 1994-03-15 1996-12-03 Trustees Of Tufts University Phosphotyrosine peptidomimetics for inhibiting SH2 domain interactions
US5716929A (en) * 1994-06-17 1998-02-10 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme
US5852010A (en) * 1996-04-03 1998-12-22 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
JP4274584B2 (ja) * 1996-12-06 2009-06-10 バーテックス ファーマシューティカルズ インコーポレイテッド インターロイキン−1β変換酵素のインヒビター

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