JP2001504331A5 - - Google Patents

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Publication number
JP2001504331A5
JP2001504331A5 JP1998521150A JP52115098A JP2001504331A5 JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5 JP 1998521150 A JP1998521150 A JP 1998521150A JP 52115098 A JP52115098 A JP 52115098A JP 2001504331 A5 JP2001504331 A5 JP 2001504331A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998521150A
Other languages
English (en)
Japanese (ja)
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JP4339406B2 (ja
JP2001504331A (ja
Filing date
Publication date
Priority claimed from GBGB9623236.8A external-priority patent/GB9623236D0/en
Priority claimed from GBGB9715674.9A external-priority patent/GB9715674D0/en
Priority claimed from GBGB9719350.2A external-priority patent/GB9719350D0/en
Application filed filed Critical
Priority claimed from PCT/GB1997/003058 external-priority patent/WO1998020142A1/en
Publication of JP2001504331A publication Critical patent/JP2001504331A/ja
Publication of JP2001504331A5 publication Critical patent/JP2001504331A5/ja
Application granted granted Critical
Publication of JP4339406B2 publication Critical patent/JP4339406B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP52115098A 1996-11-07 1997-11-06 免疫療法に使用する医薬の製造におけるSerrateまたはDeltaの使用 Expired - Fee Related JP4339406B2 (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
GBGB9623236.8A GB9623236D0 (en) 1996-11-07 1996-11-07 Notch
GB9623236.8 1996-11-07
GB9715674.9 1997-07-24
GBGB9715674.9A GB9715674D0 (en) 1997-07-24 1997-07-24 Notch
GBGB9719350.2A GB9719350D0 (en) 1997-09-11 1997-09-11 Notch
GB9719350.2 1997-09-11
PCT/GB1997/003058 WO1998020142A1 (en) 1996-11-07 1997-11-06 Notch

Publications (3)

Publication Number Publication Date
JP2001504331A JP2001504331A (ja) 2001-04-03
JP2001504331A5 true JP2001504331A5 (OSRAM) 2005-05-12
JP4339406B2 JP4339406B2 (ja) 2009-10-07

Family

ID=27268574

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52115098A Expired - Fee Related JP4339406B2 (ja) 1996-11-07 1997-11-06 免疫療法に使用する医薬の製造におけるSerrateまたはDeltaの使用

Country Status (20)

Country Link
EP (2) EP0942998B1 (OSRAM)
JP (1) JP4339406B2 (OSRAM)
KR (1) KR100393234B1 (OSRAM)
CN (2) CN1160371C (OSRAM)
AT (1) ATE299184T1 (OSRAM)
AU (1) AU736361B2 (OSRAM)
BG (1) BG103444A (OSRAM)
CA (1) CA2271248C (OSRAM)
CZ (1) CZ295997B6 (OSRAM)
DE (1) DE69733695T2 (OSRAM)
ES (1) ES2243986T3 (OSRAM)
GB (2) GB2353094B (OSRAM)
GE (1) GEP20043390B (OSRAM)
IL (1) IL129531A0 (OSRAM)
NO (1) NO992196L (OSRAM)
NZ (1) NZ335549A (OSRAM)
PL (1) PL333302A1 (OSRAM)
RO (1) RO120850B1 (OSRAM)
TR (1) TR199901000T2 (OSRAM)
WO (1) WO1998020142A1 (OSRAM)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997001571A1 (en) 1995-06-28 1997-01-16 Imperial Cancer Research Technology, Ltd. Nucleotide and protein sequences of vertebrate delta genes and methods based thereon
US5780300A (en) * 1995-09-29 1998-07-14 Yale University Manipulation of non-terminally differentiated cells using the notch pathway
GB9824045D0 (en) * 1998-11-03 1998-12-30 European Molecular Biology Lab Embl Regulator protein
GB9827604D0 (en) * 1998-12-15 1999-02-10 Lorantis Ltd Methods of immunosuppression
GB9927328D0 (en) * 1999-11-18 2000-01-12 Lorantis Ltd Immunotherapy
GB0019242D0 (en) * 2000-08-04 2000-09-27 Lorantis Ltd Assay
CA2422538C (en) 2000-09-22 2012-06-19 Genentech, Inc. Notch receptor agonists and uses
US6689744B2 (en) 2000-09-22 2004-02-10 Genentech, Inc. Notch receptor agonists and uses
RU2179862C1 (ru) * 2000-12-26 2002-02-27 Общество с ограниченной ответственностью Научно-производственный центр "МедБиоСпектр" Лекарственное средство для предотвращения отторжения трансплантата, моноклональное антитело к cd3-антигену т-лимфоцитов человека, гибридома и способ лечения больных, имеющих реакцию острого отторжения трансплантата после пересадки почки
JP2004536877A (ja) * 2001-07-25 2004-12-09 ロランティス リミテッド 免疫療法に用いるノッチシグナル伝達モジュレーター
GB0118155D0 (en) * 2001-07-25 2001-09-19 Lorantis Ltd Superantigen
GB0123379D0 (en) * 2001-09-28 2001-11-21 Lorantis Ltd Modulators
WO2003066856A1 (fr) * 2002-02-06 2003-08-14 Sanbio, Inc. Methode de differenciation/d'induction de cellules interstitielles de moelle osseuse en cellules nerveuses et en cellules musculaires du squelette par transfert du gene notch
EP1492816A2 (en) * 2002-04-05 2005-01-05 Lorantis Limited Modulators of the notch signalling pathway and uses thereof in medical treatment
AU2003255735A1 (en) * 2002-08-03 2004-02-23 Lorantis Limited Conjugate of notch signalling pathway modulators and their use in medical treatment
GB0218879D0 (en) * 2002-08-14 2002-09-25 Lorantis Ltd Medical treatment
GB0220658D0 (en) * 2002-09-05 2002-10-16 Lorantis Ltd Immunotherapy
AU2003269268A1 (en) * 2002-10-09 2004-05-04 Lorantis Limited Modulation of immune function
WO2004060262A2 (en) * 2003-01-07 2004-07-22 Lorantis Limited Modulators of notch signalling for use in immunotherpapy
GB0300428D0 (en) * 2003-01-09 2003-02-05 Lorantis Ltd Medical treatment
WO2004064863A1 (en) * 2003-01-23 2004-08-05 Lorantis Limited Treatment of autoimmune diseases using an activator for the notch signaling pathway
GB0303663D0 (en) * 2003-02-18 2003-03-19 Lorantis Ltd Assays and medical treatments
WO2004082710A1 (en) * 2003-03-21 2004-09-30 Lorantis Limited Treatment of allergic diseases using a modulator of the notch signaling pathway
WO2004083372A2 (en) * 2003-03-21 2004-09-30 Lorantis Limited Modulators of the notch signaling pathway immobilized on particles for modifying immune responses
GB0307472D0 (en) * 2003-04-01 2003-05-07 Lorantis Ltd Medical treatment
PL2032166T3 (pl) 2006-06-13 2013-09-30 Oncomed Pharm Inc Kompozycje i sposoby diagnozowania i leczenia nowotworów
US8088617B2 (en) 2007-01-24 2012-01-03 Oncomed Pharmaceuticals, Inc. Antibodies that bind the glutamate ligand binding region of Notch1
NZ590127A (en) 2008-07-08 2012-11-30 Oncomed Pharm Inc Notch1 receptor binding agents and methods of use thereof
ES2532405T3 (es) * 2008-08-22 2015-03-26 The Trustees Of Columbia University In The City Of New York Proteínas de fusión basadas en Notch3 humanas como inhibidores señuelo de la señalización de Notch3
WO2010091679A2 (de) * 2009-02-16 2010-08-19 Deutsches Rheuma-Forschungszentrum Berlin Verwendung von notch-regulatoren zur modulation der immunantwort durch induktion/suppression von interleukin-22
AU2010286518C1 (en) 2009-08-29 2015-08-27 Abbvie Inc. Therapeutic DLL4 binding proteins
PE20130580A1 (es) 2010-03-02 2013-06-02 Abbvie Inc Proteinas terapeuticas de union a dll4
CN103547275B (zh) * 2011-04-06 2016-12-28 桑比欧公司 用于调节外周免疫功能的方法和组合物
US20150316552A1 (en) * 2011-11-16 2015-11-05 Oncomed Pharmaceuticals, Inc. Human Notch Receptor Mutations and Their Use
US20150140043A1 (en) * 2012-05-10 2015-05-21 Institut National De La Sante De La Recherche Medical (Inserm) Immunomodulatory methods using notch agonists
KR101573650B1 (ko) * 2015-02-04 2015-12-01 성균관대학교산학협력단 Hcmv 바이러스 복제 억제용 조성물
BR112021003830A2 (pt) * 2018-08-28 2021-07-20 Fred Hutchinson Cancer Research Center métodos e composições para terapia celular t adotiva incorporando sinalização notch induzida

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL101728A (en) * 1991-05-03 2007-08-19 Univ Yale Human Abandonment and Delta, Restrictive Areas of Effect in Tophoric Proteins, and Methods Based on Them
US5869282A (en) * 1991-12-11 1999-02-09 Imperial Cancer Research Technology, Ltd. Nucleotide and protein sequences of the serrate gene and methods based thereon
US5786158A (en) * 1992-04-30 1998-07-28 Yale University Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
EP0742830B1 (en) * 1994-02-01 2001-07-18 THE UNITED STATES OF AMERICA, as represented by the Secretary of the Department of Health and Human Services Fusion proteins that include antibody and nonantibody portions
US5780300A (en) * 1995-09-29 1998-07-14 Yale University Manipulation of non-terminally differentiated cells using the notch pathway
AU716889B2 (en) * 1995-11-17 2000-03-09 Asahi Kasei Kogyo Kabushiki Kaisha Differentiation-suppressive polypeptide

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