JP2001503774A5 - - Google Patents

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Publication number
JP2001503774A5
JP2001503774A5 JP1998522777A JP52277798A JP2001503774A5 JP 2001503774 A5 JP2001503774 A5 JP 2001503774A5 JP 1998522777 A JP1998522777 A JP 1998522777A JP 52277798 A JP52277798 A JP 52277798A JP 2001503774 A5 JP2001503774 A5 JP 2001503774A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998522777A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001503774A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/020630 external-priority patent/WO1998020875A1/en
Publication of JP2001503774A publication Critical patent/JP2001503774A/ja
Publication of JP2001503774A5 publication Critical patent/JP2001503774A5/ja
Ceased legal-status Critical Current

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JP52277798A 1996-11-15 1997-11-13 5―ht▲下1f▼アゴニスト Ceased JP2001503774A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3095096P 1996-11-15 1996-11-15
US60/030,950 1996-11-15
PCT/US1997/020630 WO1998020875A1 (en) 1996-11-15 1997-11-13 5-ht1f agonists

Publications (2)

Publication Number Publication Date
JP2001503774A JP2001503774A (ja) 2001-03-21
JP2001503774A5 true JP2001503774A5 (enExample) 2005-05-12

Family

ID=21856862

Family Applications (1)

Application Number Title Priority Date Filing Date
JP52277798A Ceased JP2001503774A (ja) 1996-11-15 1997-11-13 5―ht▲下1f▼アゴニスト

Country Status (17)

Country Link
US (3) US5817671A (enExample)
EP (1) EP0842934B1 (enExample)
JP (1) JP2001503774A (enExample)
AT (1) ATE253063T1 (enExample)
AU (1) AU5435298A (enExample)
CA (1) CA2271272A1 (enExample)
CO (1) CO4910133A1 (enExample)
DE (1) DE69725825T2 (enExample)
DK (1) DK0842934T3 (enExample)
ES (1) ES2210463T3 (enExample)
ID (1) ID18883A (enExample)
IL (1) IL129592A0 (enExample)
NO (1) NO991974D0 (enExample)
PE (1) PE14199A1 (enExample)
PT (1) PT842934E (enExample)
WO (1) WO1998020875A1 (enExample)
ZA (1) ZA979961B (enExample)

Families Citing this family (35)

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ZA989389B (en) * 1997-11-14 2000-04-14 Lilly Co Eli Pyrrolo [3,2-b] pyridine processes and intermediates.
US5905084A (en) * 1997-11-14 1999-05-18 Eli Lilly And Company 5-HTIF -agonists effective in treating migraine
US6133290A (en) * 1998-07-31 2000-10-17 Eli Lilly And Company 5-HT1F agonists
GB9823845D0 (en) * 1998-11-02 1998-12-23 Lilly Co Eli Pharmaceutical compounds
AU1937300A (en) 1998-12-11 2000-06-26 Eli Lilly And Company Indole derivatives and their use as 5-HT1F agonists
US7482366B2 (en) 2001-12-21 2009-01-27 X-Ceptor Therapeutics, Inc. Modulators of LXR
AU2002351412B2 (en) 2001-12-21 2010-05-20 Exelixis Patent Company Llc Modulators of LXR
TWI263497B (en) 2002-03-29 2006-10-11 Lilly Co Eli Pyridinoylpiperidines as 5-HT1F agonists
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
JP2006523692A (ja) 2003-04-18 2006-10-19 イーライ リリー アンド カンパニー 5−ht1f作用薬としての(ピペリジニルオキシ)フェニル、(ピペリジニルオキシ)ピリジニル、(ピペリジニルスルファニル)フェニル、および(ピペリジニルスルファニル)ピリジニル化合物
UA82711C2 (en) 2003-09-12 2008-05-12 Эли Лилли Энд Компани Substituted 2-carbonylamino-6-piperidinaminopyridines and substituted 1-carbonylamino-3-piperidinaminobenzenes as 5-ht1f agonists
PH12012501891A1 (en) * 2003-11-21 2013-09-02 Array Biopharma Inc Akt protein kinase inhibitors
DE602004008338T2 (de) 2003-12-17 2008-05-29 Eli Lilly And Co., Indianapolis Substituierte (4-aminocyclohexen-1-yl) phenyl and (4-aminocyclohexen-1-yl) pyridinyl verbindungen als 5-ht1f agonisten
ATE532789T1 (de) 2006-07-06 2011-11-15 Array Biopharma Inc Dihydrothienopyrimidine als akt-proteinkinase- inhibitoren
US8329701B2 (en) 2006-07-06 2012-12-11 Array Biopharma Inc. Dihydrofuro pyrimidines as AKT protein kinase inhibitors
NZ573979A (en) * 2006-07-06 2012-02-24 Array Biopharma Inc Cyclopenta [d] pyrimidines as akt protein kinase inhibitors
US8063050B2 (en) * 2006-07-06 2011-11-22 Array Biopharma Inc. Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors
MX2009014013A (es) * 2007-07-05 2010-01-28 Array Biopharma Inc Pirimidil ciclopentanos como inhibidores de la proteina cinasa akt.
US9409886B2 (en) 2007-07-05 2016-08-09 Array Biopharma Inc. Pyrimidyl cyclopentanes as AKT protein kinase inhibitors
US8846683B2 (en) 2007-07-05 2014-09-30 Array Biopharma, Inc. Pyrimidyl cyclopentanes as Akt protein kinase inhibitors
ES2551352T3 (es) 2007-07-05 2015-11-18 Array Biopharma, Inc. Pirimido ciclopentanos útiles para el tratamiento de enfermedades inflamatorias o hiperproliferativas
ES2422733T3 (es) * 2008-01-09 2013-09-13 Array Biopharma Inc Pirimidilciclopentanos hidroxilados como inhibidores de proteínas cinasas AKT
EP2240455B1 (en) * 2008-01-09 2012-12-26 Array Biopharma, Inc. Hydroxylated pyrimidyl cyclopentane as akt protein kinase inhibitor
WO2010115125A2 (en) 2009-04-02 2010-10-07 Colucid Pharmaceuticals, Inc. Composition of 2,4,6-trifluoro-n-[6-(1-methyl-piperidin-4-carbonyl)-pyridin-2-yl]-benzamide
WO2011123654A1 (en) 2010-04-02 2011-10-06 Colucid Pharmaceuticals, Inc. Compositions and methods of synthesis of pyridinoylpiperidine 5-ht1f agonists
SG10201504303SA (en) 2011-04-01 2015-07-30 Genentech Inc Combinations Of AKT Inhibitor Compounds And Chemotherapeutic Agents, And Methods Of Use
TR201815685T4 (tr) 2011-04-01 2018-11-21 Genentech Inc Kanser tedavisi için akt ve mek inhibe edici bileşiklerin kombinasyonları.
BG111544A (bg) * 2013-07-29 2015-01-30 Николай Цветков Субституирани бензамидни производни като in vitro mao-b инхибитори
AU2014298017B2 (en) * 2013-08-02 2018-03-29 Pfizer Inc. Heterobicycloaryl RORC2 inhibitors and methods of use thereof
MA40759A (fr) * 2014-09-26 2017-08-01 Pfizer Modulateurs de rorc2 de type pyrrolopyridine substitué par un méthyle et trifluorométhyle et leurs procédés d'utilisation
MX376974B (es) * 2016-02-19 2025-03-07 Phoenix Molecular Designs Derivados de carboxamida útiles como inhibidores de rsk.
CA3107145A1 (en) 2018-08-24 2020-02-27 Sunshine Lake Pharma Co., Ltd. Pyridinylmethylenepiperidine derivatives and uses thereof
TWI826514B (zh) 2018-09-04 2023-12-21 美商美國禮來大藥廠 用於預防偏頭痛之拉米迪坦(lasmiditan)長期夜間投藥
US12378245B2 (en) 2019-02-11 2025-08-05 Phoenix Molecular Designs Crystalline forms of an RSK inhibitor
TWI776175B (zh) 2019-07-09 2022-09-01 美商美國禮來大藥廠 大規模製備2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺半琥珀酸鹽的方法及中間體,以及2,4,6-三氟-n-[6-(1-甲基-哌啶-4-羰基)-吡啶-2-基]-苯甲醯胺醋酸鹽之製備

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3080374A (en) * 1962-02-08 1963-03-05 Abbott Lab 2-guanidino-3-nitropyridine and derivatives thereof
MX19185A (es) * 1989-01-20 1993-12-01 Pfizer Procedimiento para preparar 3-(1,2,5,6-tretrahidropiridil)-pirrolopiridinas.
US5521196A (en) * 1994-10-05 1996-05-28 Eli Lilly And Company 5-HT1F agonists for the treatment of migraine
GB9423460D0 (en) * 1994-11-21 1995-01-11 Merck Sharp & Dohme Therapeutic agents
US5521197A (en) * 1994-12-01 1996-05-28 Eli Lilly And Company 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists
NZ305166A (en) * 1995-03-20 1998-12-23 Lilly Co Eli 5-substituted-3-(1,2,3,6-tetrahydropyridin-4-yl)- and 3-(piperidin-4-yl)-1h-indoles; preparation and medicaments

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