JP2001503735A5 - - Google Patents

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Publication number
JP2001503735A5
JP2001503735A5 JP1998504524A JP50452498A JP2001503735A5 JP 2001503735 A5 JP2001503735 A5 JP 2001503735A5 JP 1998504524 A JP1998504524 A JP 1998504524A JP 50452498 A JP50452498 A JP 50452498A JP 2001503735 A5 JP2001503735 A5 JP 2001503735A5
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JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP1998504524A
Other languages
English (en)
Japanese (ja)
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JP2001503735A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/012544 external-priority patent/WO1998000110A1/en
Publication of JP2001503735A publication Critical patent/JP2001503735A/ja
Publication of JP2001503735A5 publication Critical patent/JP2001503735A5/ja
Ceased legal-status Critical Current

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JP50452498A 1996-07-03 1997-07-03 親水性活性試薬のためのエマルジョン処方物 Ceased JP2001503735A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US67686796A 1996-07-03 1996-07-03
US08/676,867 1996-07-03
PCT/US1997/012544 WO1998000110A1 (en) 1996-07-03 1997-07-03 Emulsion formulations for hydrophilic active agents

Publications (2)

Publication Number Publication Date
JP2001503735A JP2001503735A (ja) 2001-03-21
JP2001503735A5 true JP2001503735A5 (enExample) 2004-12-09

Family

ID=24716366

Family Applications (1)

Application Number Title Priority Date Filing Date
JP50452498A Ceased JP2001503735A (ja) 1996-07-03 1997-07-03 親水性活性試薬のためのエマルジョン処方物

Country Status (6)

Country Link
US (3) US6610321B2 (enExample)
EP (1) EP0910343A1 (enExample)
JP (1) JP2001503735A (enExample)
AU (1) AU727447B2 (enExample)
CA (1) CA2259179C (enExample)
WO (1) WO1998000110A1 (enExample)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6008202A (en) 1995-01-23 1999-12-28 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US6120794A (en) 1995-09-26 2000-09-19 University Of Pittsburgh Emulsion and micellar formulations for the delivery of biologically active substances to cells
US20010009904A1 (en) * 1997-12-30 2001-07-26 Jon A. Wolff Process of delivering a polynucleotide to a cell via the vascular system
US6258792B1 (en) 1996-04-12 2001-07-10 University Of Pittsburgh Cationic cholesteryl derivatives containing cyclic polar groups
WO1997039019A1 (en) 1996-04-12 1997-10-23 University Of Pittsburgh Novel cationic cholesteryl derivatives containing cyclic polar groups
JP2001503735A (ja) 1996-07-03 2001-03-21 ユニバーシティ オブ ピッツバーグ 親水性活性試薬のためのエマルジョン処方物
US6458373B1 (en) 1997-01-07 2002-10-01 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
EP1012331B1 (en) 1997-07-01 2006-03-29 Isis Pharmaceuticals, Inc. Compositions and methods for the delivery of oligonucleotides via the alimentary canal
US6989264B2 (en) * 1997-09-05 2006-01-24 Targeted Genetics Corporation Methods for generating high titer helper-free preparations of released recombinant AAV vectors
KR20010042069A (ko) * 1998-03-20 2001-05-25 베니텍 오스트레일리아 리미티드 유전자 발현 조절방법
AUPP249298A0 (en) * 1998-03-20 1998-04-23 Ag-Gene Australia Limited Synthetic genes and genetic constructs comprising same I
AU745880B2 (en) * 1998-05-21 2002-04-11 Isis Pharmaceuticals, Inc. Compositions and methods for non-parenteral delivery of oligonucleotides
US7030155B2 (en) 1998-06-05 2006-04-18 Sonus Pharmaceuticals, Inc. Emulsion vehicle for poorly soluble drugs
FR2797188A1 (fr) * 1999-08-04 2001-02-09 Univ Paris Nord Laboratoire De Composes lipidiques cationiques et leurs utilisation pour le transfert de substances d'interet therapeutique chargees negativement
US6423885B1 (en) * 1999-08-13 2002-07-23 Commonwealth Scientific And Industrial Research Organization (Csiro) Methods for obtaining modified phenotypes in plant cells
US7678415B2 (en) * 2000-10-04 2010-03-16 Kyowa Hakko Kirin Co., Ltd. Method of coating fine particles with lipid film
ES2294147T5 (es) * 2001-07-27 2011-04-04 N.V. Nutricia Composiciones enterales para la prevención y/o tratamiento de la sepsis.
US20030059899A1 (en) * 2001-09-26 2003-03-27 Murali Sastry Method for the hydrophobisation of DNA molecules
JP4886297B2 (ja) * 2002-11-01 2012-02-29 バイオデリバリー サイエンシーズ インターナショナル インコーポレイティッド ジオデート送達媒体
US7179484B2 (en) * 2002-11-06 2007-02-20 Azaya Therapeutics, Inc. Protein-stabilized liposomal formulations of pharmaceutical agents
KR100703872B1 (ko) * 2003-10-10 2007-04-09 주식회사 삼양사 양친성 블록 공중합체 및 이를 포함하는 약물 전달용고분자 조성물
EA200600877A1 (ru) * 2003-10-31 2006-12-29 Тева Фармасьютикал Индастриз, Лтд. Наночастицы для доставки лекарств
US7348802B2 (en) * 2004-06-15 2008-03-25 Stmicroelectronics Pvt. Ltd. Differential receiver
US7871632B2 (en) * 2004-07-12 2011-01-18 Adventrx Pharmaceuticals, Inc. Compositions for delivering highly water soluble drugs
ES2640060T3 (es) * 2005-01-28 2017-10-31 Kyowa Hakko Kirin Co., Ltd. Proceso para producir una partícula fina revestida
KR20060119739A (ko) * 2005-05-18 2006-11-24 엘지전자 주식회사 구간 통과시간에 대한 예측정보를 제공하고 이를 이용하는방법 및 장치
KR20060119743A (ko) * 2005-05-18 2006-11-24 엘지전자 주식회사 구간 속도에 대한 예측정보를 제공하고 이를 이용하는 방법및 장치
KR20060119746A (ko) 2005-05-18 2006-11-24 엘지전자 주식회사 교통상태에 대한 정보를 제공하고 이를 이용하는 방법 및장치
KR100711866B1 (ko) * 2005-05-18 2007-04-25 엘지전자 주식회사 소통상태에 대한 예측정보를 제공하고 이를 이용하는 방법및 장치
KR20060119741A (ko) * 2005-05-18 2006-11-24 엘지전자 주식회사 소통상태의 추이정보를 제공하고 이를 이용하는 방법 및장치
KR20060119742A (ko) * 2005-05-18 2006-11-24 엘지전자 주식회사 도로 정보를 제공하고 이를 이용하는 방법 및 장치
US8711850B2 (en) * 2005-07-08 2014-04-29 Lg Electronics Inc. Format for providing traffic information and a method and apparatus for using the format
KR101254219B1 (ko) * 2006-01-19 2013-04-23 엘지전자 주식회사 링크 식별 방법 및 링크 식별 장치
US8728527B2 (en) 2006-07-24 2014-05-20 Luminus Biosciences, Inc. Solid nanoparticle formulation of water insoluble pharmaceutical substances with reduced ostwald ripening
US8877206B2 (en) 2007-03-22 2014-11-04 Pds Biotechnology Corporation Stimulation of an immune response by cationic lipids
US20100297242A1 (en) * 2007-10-17 2010-11-25 Tae-Gwan Park Ldl-like cationic nanoparticles for deliverying nucleic acid gene, method for preparing thereof and method for deliverying nucleic acid gene using the same
AU2009236306B2 (en) 2008-04-17 2015-04-02 Pds Biotechnology Corporation Stimulation of an immune response by enantiomers of cationic lipids
WO2009142892A1 (en) * 2008-05-19 2009-11-26 The University Of North Carolina At Chapel Hill Methods and compositions comprising novel cationic lipids
CA2806295A1 (en) * 2009-08-03 2011-02-10 Alnylam Pharmaceuticals, Inc. Methods and compositions for treating insects
NZ603453A (en) * 2010-05-06 2014-12-24 Alphacore Pharma Llc Delivery of cholesteryl ester to steroidogenic tissues
HUE047796T2 (hu) * 2010-07-06 2020-05-28 Glaxosmithkline Biologicals Sa RNS bevitele több immunútvonal bekapcsolására
DK2590676T3 (en) 2010-07-06 2016-10-24 Glaxosmithkline Biologicals Sa Virionlignende feed particles to self-replicating RNA molecules
US9770463B2 (en) * 2010-07-06 2017-09-26 Glaxosmithkline Biologicals Sa Delivery of RNA to different cell types
NZ606591A (en) 2010-07-06 2015-02-27 Novartis Ag Cationic oil-in-water emulsions
RS54489B1 (sr) 2010-07-06 2016-06-30 Glaxosmithkline Biologicals Sa Lipozomi sa lipidima koji imaju poboljšanu pka vrednost za oslobađanje rnk
JP5940064B2 (ja) 2010-07-06 2016-06-29 ノバルティス アーゲー 低用量のrnaを用いた大型哺乳動物の免疫化
SMT202200311T1 (it) 2010-08-31 2022-09-14 Glaxosmithkline Biologicals Sa Liposomi pegilati per somministrare rna codificante un immunogene
EP3520813B1 (en) 2010-10-11 2023-04-19 GlaxoSmithKline Biologicals S.A. Antigen delivery platforms
CN103781470A (zh) 2011-07-06 2014-05-07 诺华股份有限公司 包含核酸的水包油乳液
EP3854413A1 (en) 2011-07-06 2021-07-28 GlaxoSmithKline Biologicals SA Immunogenic combination compositions and uses thereof
EP3456316A1 (en) 2011-07-06 2019-03-20 GlaxoSmithKline Biologicals S.A. Cationic oil-in-water emulsions
AU2013274235B2 (en) 2012-06-15 2018-01-18 Samir N. Khleif Cationic lipid vaccine compositions and methods of use
KR101493930B1 (ko) * 2012-09-12 2015-02-16 사회복지법인 삼성생명공익재단 표적지향형 난용성 약물 전달체
AU2013317805B2 (en) 2012-09-21 2018-07-26 Pds Biotechnology Corporation Improved vaccine compositions and methods of use
EP3556353A3 (en) 2014-02-25 2020-03-18 Merck Sharp & Dohme Corp. Lipid nanoparticle vaccine adjuvants and antigen delivery systems
US11612652B2 (en) 2015-11-13 2023-03-28 Pds Biotechnology Corporation Lipids as synthetic vectors to enhance antigen processing and presentation ex-vivo in dendritic cell therapy
MX2019013259A (es) 2017-05-08 2020-01-13 Gritstone Oncology Inc Vectores de neoantigeno de alfavirus.
CN111655238A (zh) 2017-12-05 2020-09-11 Pds生物科技公司 用于刺激i型干扰素基因的包括阳离子脂质的方法和组合物
EP4495597A3 (en) 2018-01-04 2025-04-30 Iconic Therapeutics LLC Anti-tissue factor antibodies, antibody-drug conjugates, and related methods
CN109316599A (zh) * 2018-08-24 2019-02-12 上海交通大学医学院附属瑞金医院 一种抑肽酶或其突变体、衍生物、类似物或其组成片段的应用
JP7457733B2 (ja) 2019-05-30 2024-03-28 グリットストーン バイオ インコーポレイテッド 改変アデノウイルス
EP4103227A1 (en) 2020-02-14 2022-12-21 Merck Sharp & Dohme LLC Hpv vaccine
EP4192496A4 (en) 2020-08-06 2025-01-01 Gritstone bio, Inc. MULTIEPITOP VACCINE CASSETTES
TW202245835A (zh) 2021-02-04 2022-12-01 美商默沙東有限責任公司 用於肺炎球菌結合物疫苗之奈米乳化液佐劑組合物
CN118019547A (zh) 2021-08-19 2024-05-10 默沙东有限责任公司 热稳定脂质纳米粒子及其使用方法
KR20260021734A (ko) 2023-06-09 2026-02-13 머크 샤프 앤드 돔 엘엘씨 인간 유두종바이러스 백신을 위한 나노에멀젼 아주반트 조성물

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545412A (en) 1985-01-07 1996-08-13 Syntex (U.S.A.) Inc. N-[1, (1-1)-dialkyloxy]-and N-[1, (1-1)-dialkenyloxy]-alk-1-yl-n,n,n-tetrasubstituted ammonium lipids and uses therefor
US5374548A (en) 1986-05-02 1994-12-20 Genentech, Inc. Methods and compositions for the attachment of proteins to liposomes using a glycophospholipid anchor
US5540933A (en) 1985-05-31 1996-07-30 La Jolla Cancer Research Foundation Isolation and use of fibronectin receptor
SE456136B (sv) 1985-06-17 1988-09-12 Oncholab Ab Forfarande for framstellning av en med ett lipofilt biologiskt aktivt emne bemengd berare pa basis av rekonstituerat ldl (lagdensitetslipoprotein)
GB8822857D0 (en) * 1988-09-29 1988-11-02 Patralan Ltd Pharmaceutical formulations
DE3908047A1 (de) 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
FR2649321A1 (fr) 1989-07-07 1991-01-11 Inst Nat Sante Rech Med Compositions a base de derives nucleotidiques, leurs procedes de preparation, et leurs utilisations notamment en tant que compositions pharmaceutiques
US5676954A (en) 1989-11-03 1997-10-14 Vanderbilt University Method of in vivo delivery of functioning foreign genes
FR2664500B1 (fr) 1990-07-13 1994-10-28 Lille Ii Universite Droit Sant Procede de preparation d'une lipoproteine modifiee par incorporation d'une substance active lipophile, lipoproteine modifiee ainsi obtenue et composition pharmaceutique ou cosmetique la contenant.
US5283185A (en) 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
US5756353A (en) 1991-12-17 1998-05-26 The Regents Of The University Of California Expression of cloned genes in the lung by aerosol-and liposome-based delivery
IL101241A (en) 1992-03-16 1997-11-20 Yissum Res Dev Co Pharmaceutical or cosmetic composition comprising stabilized oil-in-water type emulsion as carrier
BR9201168A (pt) 1992-04-02 1994-04-12 Zerbini E J Fundacao Microemulsoes usadas como velculo para carregar quimioterapicos as celulas neoplasicas
CA2134773A1 (en) 1992-06-04 1993-12-09 Robert J. Debs Methods and compositions for in vivo gene therapy
AU6254494A (en) 1993-02-16 1994-09-14 Virginia Tech Intellectual Properties, Inc. Polyelectrolyte dna conjugation and genetic transformation of an animal
US5576016A (en) * 1993-05-18 1996-11-19 Pharmos Corporation Solid fat nanoemulsions as drug delivery vehicles
US5578475A (en) 1993-07-12 1996-11-26 Life Technologies, Inc. Composition and methods for transfecting eukaryotic cells
JP4285766B2 (ja) 1994-03-23 2009-06-24 オハイオ ユニバーシティ 緻密にした核酸および細胞へのデリバリ
US6077835A (en) 1994-03-23 2000-06-20 Case Western Reserve University Delivery of compacted nucleic acid to cells
US5851510A (en) 1994-05-16 1998-12-22 The Board Of Regents Of The University Of Michigan Hepatocyte-selective oil-in-water emulsion
US5635487A (en) 1994-12-29 1997-06-03 Wolff; Jon A. Amphipathic, micellar delivery systems for biologically active polyions
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US6120794A (en) 1995-09-26 2000-09-19 University Of Pittsburgh Emulsion and micellar formulations for the delivery of biologically active substances to cells
WO1997039019A1 (en) 1996-04-12 1997-10-23 University Of Pittsburgh Novel cationic cholesteryl derivatives containing cyclic polar groups
JP2001503735A (ja) 1996-07-03 2001-03-21 ユニバーシティ オブ ピッツバーグ 親水性活性試薬のためのエマルジョン処方物

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