JP2000511877A5 - - Google Patents

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Publication number
JP2000511877A5
JP2000511877A5 JP1997528505A JP52850597A JP2000511877A5 JP 2000511877 A5 JP2000511877 A5 JP 2000511877A5 JP 1997528505 A JP1997528505 A JP 1997528505A JP 52850597 A JP52850597 A JP 52850597A JP 2000511877 A5 JP2000511877 A5 JP 2000511877A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP1997528505A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000511877A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/000255 external-priority patent/WO1997029101A1/en
Publication of JP2000511877A publication Critical patent/JP2000511877A/ja
Publication of JP2000511877A5 publication Critical patent/JP2000511877A5/ja
Abandoned legal-status Critical Current

Links

JP09528505A 1996-02-07 1997-01-02 医薬としての新規な環状アミノ酸 Abandoned JP2000511877A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1127896P 1996-02-07 1996-02-07
US60/011,278 1996-02-07
PCT/US1997/000255 WO1997029101A1 (en) 1996-02-07 1997-01-02 Novel cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
JP2000511877A JP2000511877A (ja) 2000-09-12
JP2000511877A5 true JP2000511877A5 (enExample) 2004-11-11

Family

ID=21749660

Family Applications (1)

Application Number Title Priority Date Filing Date
JP09528505A Abandoned JP2000511877A (ja) 1996-02-07 1997-01-02 医薬としての新規な環状アミノ酸

Country Status (22)

Country Link
US (1) US5929088A (enExample)
EP (1) EP0888325B1 (enExample)
JP (1) JP2000511877A (enExample)
KR (1) KR19990082349A (enExample)
AT (1) ATE218135T1 (enExample)
AU (1) AU720628B2 (enExample)
BR (1) BR9707366A (enExample)
CA (1) CA2244708A1 (enExample)
CZ (1) CZ296052B6 (enExample)
DE (1) DE69712877T2 (enExample)
DK (1) DK0888325T3 (enExample)
EA (1) EA001534B1 (enExample)
ES (1) ES2176668T3 (enExample)
HU (1) HUP9901074A3 (enExample)
IL (1) IL125562A (enExample)
NO (1) NO983612L (enExample)
NZ (1) NZ326669A (enExample)
PL (1) PL328432A1 (enExample)
PT (1) PT888325E (enExample)
SK (1) SK282665B6 (enExample)
WO (1) WO1997029101A1 (enExample)
ZA (1) ZA97991B (enExample)

Families Citing this family (38)

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KR100491282B1 (ko) 1996-07-24 2005-05-24 워너-램버트 캄파니 엘엘씨 통증 치료용 이소부틸가바 및 그의 유도체
AU752444B2 (en) 1997-09-18 2002-09-19 Warner-Lambert Company Novel stereoselective processes for the preparation of gabapentin analogues
DE19751062A1 (de) * 1997-11-18 1999-07-08 Univ Ludwigs Albert An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
US6984659B2 (en) 1997-11-18 2006-01-10 Klinikum Der Albert-Ludwigs Universitaet 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
KR20010033153A (ko) * 1997-12-16 2001-04-25 로즈 암스트롱, 크리스틴 에이. 트러트웨인 4(3)-치환-4(3)-아미노메틸-(티오)피란 또는 -피페리딘유도체(=가바펜틴 동족체), 그의 제법 및 신경 질환 치료용도
JP2003528148A (ja) * 2000-03-28 2003-09-24 デロレンゾ、ロバート・ジェイ 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する
EP1343805A4 (en) 2000-10-06 2005-07-20 Xenoport Inc COMPOUNDS DERIVED FROM GALLENIC ACIDS FOR THE PROVISION OF CONTINUING SYSTEMIC CONCENTRATIONS OF MEDICINAL PRODUCTS AFTER ORAL ADMINISTRATION
WO2002032376A2 (en) 2000-10-06 2002-04-25 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
GB2368579A (en) * 2000-10-31 2002-05-08 Parke Davis & Co Ltd Azole pharmaceutical agents
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2002100344A2 (en) 2001-06-11 2002-12-19 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
WO2002100347A2 (en) 2001-06-11 2002-12-19 Xenoport, Inc. Prodrugs of gaba analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US6927036B2 (en) 2002-02-19 2005-08-09 Xero Port, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
AU2003222033A1 (en) 2002-03-20 2003-10-08 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
WO2003099338A2 (en) 2002-05-17 2003-12-04 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US20040092498A1 (en) * 2002-08-16 2004-05-13 David Blakemore Substituted glycine derivatives for use as medicaments
AU2003297927A1 (en) 2002-12-11 2004-06-30 Xenoport, Inc. Prodrugs of fused gaba analogs, pharmaceutical compositions and uses thereof
ES2341240T3 (es) 2002-12-13 2010-06-17 Warner-Lambert Company Llc Ligando alfa-2-delta para tratar los sintomas del tracto urinario inferior.
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
CA2537837A1 (en) 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
MXPA06002789A (es) 2003-09-12 2006-06-14 Pfizer Combinaciones que comprenden ligandos alfa-2-delta.
MXPA06003043A (es) 2003-09-17 2006-05-31 Xenoport Inc Tratamiento o prevencion del sindrome piernas inquietas utilizando prodrogas de analogos gaba.
WO2005037784A2 (en) 2003-10-14 2005-04-28 Xenoport, Inc. Crystalline form of gamma-aminobutyric acid analog
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
EP1811986B1 (en) 2004-11-04 2014-03-26 XenoPort, Inc. Gabapentin prodrug sustained release oral dosage forms
UA94979C2 (uk) 2006-12-22 2011-06-25 Рекордати Айеленд Лимитед КОМБІНОВАНА ТЕРАПІЯ ПОРУШЕНЬ НИЖНІХ СЕЧОВИВІДНИХ ШЛЯХІВ ЛІГАНДАМИ α2δ І НПЗП
CA2697254A1 (en) * 2007-08-23 2009-02-26 Novartis Ag Aminobenzyl-substituted cyclic sulfones useful as bace inhibitors
US7872046B2 (en) 2008-01-25 2011-01-18 Xenoport, Inc. Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
JP5563483B2 (ja) 2008-01-25 2014-07-30 ゼノポート,インコーポレイティド アシロキシアルキルカルバメートプロドラッグの合成に使用されるアシロキシアルキルチオカーボネートの鏡像異性的な分解
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
BRPI0919811B1 (pt) 2008-10-08 2022-04-19 Xgene Pharmaceutical Inc Conjugados de gaba e métodos de uso dos mesmos
WO2010084797A1 (ja) * 2009-01-21 2010-07-29 第一三共株式会社 含ヘテロ原子化合物
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
AU2014209028C1 (en) 2013-01-28 2019-08-29 Hector L. Lopez Methods of improving tolerability, pharmacodynamics, and efficacy of b-alanine and use therefor
AU2019271799B2 (en) 2018-05-14 2023-10-12 Xgene Pharmaceutical Inc. Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
WO1993001171A1 (fr) * 1991-07-09 1993-01-21 Nippon Soda Co., Ltd. Derive de cyclohexanedione heterocyclique, production de celui-ci, et herbicide
US5514801A (en) * 1992-12-29 1996-05-07 Monsanto Company Cyclic sulfone containing retroviral protease inhibitors
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
US5527194A (en) * 1994-02-02 1996-06-18 Brunswick Corporation Thrust sensor for marine drives
US5491152A (en) * 1994-03-23 1996-02-13 The Du Pont Merck Pharmaceutical Company Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
US5760006A (en) * 1997-06-23 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating psoriasis

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