|
US6001876A
(en)
|
1996-07-24 |
1999-12-14 |
Warner-Lambert Company |
Isobutylgaba and its derivatives for the treatment of pain
|
|
NZ502786A
(en)
*
|
1997-09-18 |
2002-05-31 |
Warner Lambert Co |
Preparation of gabapentin analogues comprised of adding cyclohexanone to sodium hydride and finally heating the formed lactam in HCl and dioxan
|
|
US6984659B2
(en)
|
1997-11-18 |
2006-01-10 |
Klinikum Der Albert-Ludwigs Universitaet |
2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
|
|
DE19751062A1
(de)
|
1997-11-18 |
1999-07-08 |
Univ Ludwigs Albert |
An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
|
|
KR20010033153A
(ko)
*
|
1997-12-16 |
2001-04-25 |
로즈 암스트롱, 크리스틴 에이. 트러트웨인 |
4(3)-치환-4(3)-아미노메틸-(티오)피란 또는 -피페리딘유도체(=가바펜틴 동족체), 그의 제법 및 신경 질환 치료용도
|
|
AU2001247762A1
(en)
*
|
2000-03-28 |
2001-10-08 |
Delorenzo, Robert, J |
Inhibition of a novel calcium injury current that forms in neurons during injury prevents neuronal cell death
|
|
AU2002211863A1
(en)
|
2000-10-06 |
2002-04-15 |
Xenoport, Inc. |
Bile-acid derived compounds for providing sustained systemic concentrations of drugs after oral administration
|
|
EP1361847A2
(en)
|
2000-10-06 |
2003-11-19 |
Xenoport, Inc. |
Bile-acid conjugates for providing sustained systemic concentrations of drugs
|
|
GB2368579A
(en)
*
|
2000-10-31 |
2002-05-08 |
Parke Davis & Co Ltd |
Azole pharmaceutical agents
|
|
US7420002B2
(en)
|
2001-06-11 |
2008-09-02 |
Xenoport |
Amino acid conjugates providing for sustained systemic concentrations of GABA analogues
|
|
US7232924B2
(en)
|
2001-06-11 |
2007-06-19 |
Xenoport, Inc. |
Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
|
|
US6818787B2
(en)
|
2001-06-11 |
2004-11-16 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
|
US7186855B2
(en)
|
2001-06-11 |
2007-03-06 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
|
MXPA03011566A
(es)
|
2001-06-11 |
2004-10-28 |
Xenoport Inc |
Formas de dosificacion de profarmacos de analogos de gaba administrados oralmente que tienen toxicidad reducida.
|
|
US8048917B2
(en)
|
2005-04-06 |
2011-11-01 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
|
US6927036B2
(en)
|
2002-02-19 |
2005-08-09 |
Xero Port, Inc. |
Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
|
|
US7026351B2
(en)
|
2002-03-20 |
2006-04-11 |
Xenoport, Inc. |
Cyclic 1-(acyloxy)-alkyl prodrugs of GABA analogs, compositions and uses thereof
|
|
AU2003243180A1
(en)
|
2002-05-17 |
2003-12-12 |
Xenoport, Inc. |
Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
|
|
US20040092498A1
(en)
*
|
2002-08-16 |
2004-05-13 |
David Blakemore |
Substituted glycine derivatives for use as medicaments
|
|
US7060727B2
(en)
|
2002-12-11 |
2006-06-13 |
Xenoport, Inc. |
Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
|
|
DE60332387D1
(de)
|
2002-12-13 |
2010-06-10 |
Warner Lambert Co |
Alpha-2-delta-ligand zur behandlung vonsymptomen der unteren harnwege
|
|
CA2451267A1
(en)
|
2002-12-13 |
2004-06-13 |
Warner-Lambert Company Llc |
Pharmaceutical uses for alpha2delta ligands
|
|
KR20060119971A
(ko)
|
2003-09-11 |
2006-11-24 |
제노포트 인코포레이티드 |
Ｇａｂａ 유사체의 전구약물을 이용한 요실금의 치료및/또는 예방
|
|
DE602004024317D1
(de)
|
2003-09-12 |
2010-01-07 |
Pfizer |
Kombinationen aus alpha-2-delta liganden und serotonin / noradrenalin-wiederaufnahmehemmern
|
|
WO2005027850A2
(en)
|
2003-09-17 |
2005-03-31 |
Xenoport, Inc. |
Treating or preventing restless legs syndrome using prodrugs of gaba analogs
|
|
MXPA06004088A
(es)
|
2003-10-14 |
2006-06-27 |
Xenoport Inc |
Forma cristalina de un analogo del acido gamma-aminobutirico.
|
|
WO2005060968A1
(en)
|
2003-12-11 |
2005-07-07 |
Sepracor Inc. |
Combination of a sedative and a neurotransmitter modulator, and methods for improving sleep quality and treating depression
|
|
EP1811986B1
(en)
|
2004-11-04 |
2014-03-26 |
XenoPort, Inc. |
Gabapentin prodrug sustained release oral dosage forms
|
|
ATE511860T1
(de)
|
2006-12-22 |
2011-06-15 |
Recordati Ireland Ltd |
Kombinationstherapie für erkrankungen der unteren harnwege mit 2 liganden und nsar
|
|
WO2009024615A1
(en)
*
|
2007-08-23 |
2009-02-26 |
Novartis Ag |
Aminobenzyl-substituted cyclic sulfones useful as bace inhibitors
|
|
EP2250143B1
(en)
|
2008-01-25 |
2016-04-20 |
XenoPort, Inc. |
Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
|
|
US7872046B2
(en)
|
2008-01-25 |
2011-01-18 |
Xenoport, Inc. |
Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
|
|
WO2009094577A2
(en)
|
2008-01-25 |
2009-07-30 |
Xenoport, Inc. |
Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
|
|
ES2589915T3
(es)
|
2008-10-08 |
2016-11-17 |
Xgene Pharmaceutical Inc |
Conjugados de GABA y métodos de utilización de los mismos
|
|
WO2010084797A1
(ja)
*
|
2009-01-21 |
2010-07-29 |
第一三共株式会社 |
含ヘテロ原子化合物
|
|
US9066853B2
(en)
|
2013-01-15 |
2015-06-30 |
Warsaw Orthopedic, Inc. |
Clonidine compounds in a biodegradable fiber
|
|
WO2014117176A1
(en)
|
2013-01-28 |
2014-07-31 |
Lopez Hector L |
Methods of improving tolerability, pharmacodynamics, and efficacy of b-alanine and use therefor
|
|
CA3099775A1
(en)
|
2018-05-14 |
2019-11-21 |
Xgene Pharmaceutical Inc. |
Process for making 1-(acyloxy)-alkyl-carabmate drug conjugates of naproxen and pregabalin
|