JP2000511877A5 - - Google Patents

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Publication number
JP2000511877A5
JP2000511877A5 JP1997528505A JP52850597A JP2000511877A5 JP 2000511877 A5 JP2000511877 A5 JP 2000511877A5 JP 1997528505 A JP1997528505 A JP 1997528505A JP 52850597 A JP52850597 A JP 52850597A JP 2000511877 A5 JP2000511877 A5 JP 2000511877A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
JP1997528505A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000511877A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/000255 external-priority patent/WO1997029101A1/en
Publication of JP2000511877A publication Critical patent/JP2000511877A/ja
Publication of JP2000511877A5 publication Critical patent/JP2000511877A5/ja
Abandoned legal-status Critical Current

Links

JP09528505A 1996-02-07 1997-01-02 医薬としての新規な環状アミノ酸 Abandoned JP2000511877A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1127896P 1996-02-07 1996-02-07
US60/011,278 1996-02-07
PCT/US1997/000255 WO1997029101A1 (en) 1996-02-07 1997-01-02 Novel cyclic amino acids as pharmaceutical agents

Publications (2)

Publication Number Publication Date
JP2000511877A JP2000511877A (ja) 2000-09-12
JP2000511877A5 true JP2000511877A5 (enExample) 2004-11-11

Family

ID=21749660

Family Applications (1)

Application Number Title Priority Date Filing Date
JP09528505A Abandoned JP2000511877A (ja) 1996-02-07 1997-01-02 医薬としての新規な環状アミノ酸

Country Status (22)

Country Link
US (1) US5929088A (enExample)
EP (1) EP0888325B1 (enExample)
JP (1) JP2000511877A (enExample)
KR (1) KR19990082349A (enExample)
AT (1) ATE218135T1 (enExample)
AU (1) AU720628B2 (enExample)
BR (1) BR9707366A (enExample)
CA (1) CA2244708A1 (enExample)
CZ (1) CZ296052B6 (enExample)
DE (1) DE69712877T2 (enExample)
DK (1) DK0888325T3 (enExample)
EA (1) EA001534B1 (enExample)
ES (1) ES2176668T3 (enExample)
HU (1) HUP9901074A3 (enExample)
IL (1) IL125562A (enExample)
NO (1) NO983612L (enExample)
NZ (1) NZ326669A (enExample)
PL (1) PL328432A1 (enExample)
PT (1) PT888325E (enExample)
SK (1) SK282665B6 (enExample)
WO (1) WO1997029101A1 (enExample)
ZA (1) ZA97991B (enExample)

Families Citing this family (38)

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ES2200184T7 (es) 1996-07-24 2015-02-10 Warner-Lambert Company Llc Isobutilgaba y sus derivados para el tratamiento del dolor
JP3878809B2 (ja) 1997-09-18 2007-02-07 ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー ガバペンチン類似体を製造するための新規な立体選択的方法
US6984659B2 (en) 1997-11-18 2006-01-10 Klinikum Der Albert-Ludwigs Universitaet 2-pyrrolidinone derivatives substituted at position 4 for reducing the extracellular glutamate level
DE19751062A1 (de) * 1997-11-18 1999-07-08 Univ Ludwigs Albert An 4-Stellung substituierte 2-Pyrrolidinon-Derivate zur Verringerung des extrazellulären Glutamat-Spiegels
HUP0100069A3 (en) * 1997-12-16 2002-04-29 Warner Lambert Co 4(3)substituted-4(3)-aminomethyl-pyran, or -thiopyran-piperidine derivatives, their preparation and their use in the treatment of neurological disorders
JP2003528148A (ja) * 2000-03-28 2003-09-24 デロレンゾ、ロバート・ジェイ 損傷に際して神経細胞中に形成される新規カルシウム損傷電流の阻害は神経細胞死を抑制する
EP1361847A2 (en) 2000-10-06 2003-11-19 Xenoport, Inc. Bile-acid conjugates for providing sustained systemic concentrations of drugs
EP1343805A4 (en) 2000-10-06 2005-07-20 Xenoport Inc COMPOUNDS DERIVED FROM GALLENIC ACIDS FOR THE PROVISION OF CONTINUING SYSTEMIC CONCENTRATIONS OF MEDICINAL PRODUCTS AFTER ORAL ADMINISTRATION
GB2368579A (en) * 2000-10-31 2002-05-08 Parke Davis & Co Ltd Azole pharmaceutical agents
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US6818787B2 (en) 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2002100344A2 (en) 2001-06-11 2002-12-19 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
EP1404324B2 (en) 2001-06-11 2011-04-06 XenoPort, Inc. Prodrugs of gaba analogs, compositions and uses thereof
AU2002316231A1 (en) 2002-02-19 2003-09-29 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
AU2003222033A1 (en) 2002-03-20 2003-10-08 Xenoport Cyclic 1-(acyloxy)-alkyl prodrugs of gaba analogs, compositions and uses thereof
AU2003243180A1 (en) 2002-05-17 2003-12-12 Xenoport, Inc. Amino acid conjugates providing for sustained systemic concentrations of gaba analogues
US20040092498A1 (en) * 2002-08-16 2004-05-13 David Blakemore Substituted glycine derivatives for use as medicaments
US7060727B2 (en) 2002-12-11 2006-06-13 Xenoport, Inc. Prodrugs of fused GABA analogs, pharmaceutical compositions and uses thereof
CA2451267A1 (en) 2002-12-13 2004-06-13 Warner-Lambert Company Llc Pharmaceutical uses for alpha2delta ligands
NZ539972A (en) 2002-12-13 2008-05-30 Warner Lambert Co Alpha-2-delta ligand to treat lower urinary tract symptoms
CA2537837A1 (en) 2003-09-11 2005-03-24 Xenoport, Inc. Treating and/or preventing urinary incontinence using prodrugs of gaba analogs
EP2156863A3 (en) 2003-09-12 2011-01-12 Pfizer Limited Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline reuptake inhibitors
CA2538802C (en) 2003-09-17 2015-01-27 Xenoport, Inc. Treating or preventing restless legs syndrome using prodrugs of gaba analogs
PT1677767E (pt) 2003-10-14 2011-10-13 Xenoport Inc Forma cristalina de análogo de ácido gama-aminobutírico
JP5646126B2 (ja) 2003-12-11 2014-12-24 サノビオン ファーマシューティカルズ インクSunovion Pharmaceuticals Inc. 鎮静剤と神経伝達物質調節剤の併用、および睡眠の質の向上方法および鬱の治療方法
WO2006050514A1 (en) 2004-11-04 2006-05-11 Xenoport, Inc. Gabapentin prodrug sustained release oral dosage forms
PL2125021T3 (pl) 2006-12-22 2011-10-31 Recordati Ireland Ltd Leczenie skojarzone zaburzeń w obrębie dolnych dróg moczowych z zastosowaniem ligandów α2δ i przeciwzapalnych leków niesterydowych (NSAIDs)
BRPI0815673A2 (pt) * 2007-08-23 2015-02-18 Novartis Ag Sulfonas cíclicas substituídas por aminobenzila úteis como inibidores de bace.
EP2250143B1 (en) 2008-01-25 2016-04-20 XenoPort, Inc. Method for the enzymatic kinetic resolution of acyloxyalkyl thiocarbonates used for the synthesis of acyloxyalkyl carbamates
US7872046B2 (en) 2008-01-25 2011-01-18 Xenoport, Inc. Crystalline form of a (3S)-aminomethyl-5-methyl-hexanoic acid prodrug and methods of use
WO2009094577A2 (en) 2008-01-25 2009-07-30 Xenoport, Inc. Mesophasic forms of (3s)-aminomethyl-5-methyl-hexanoic acid prodrugs and methods of use
EP3075722A1 (en) 2008-10-08 2016-10-05 Xgene Pharmaceutical Inc Gaba conjugates and methods of use thereof
WO2010084797A1 (ja) * 2009-01-21 2010-07-29 第一三共株式会社 含ヘテロ原子化合物
US9066853B2 (en) 2013-01-15 2015-06-30 Warsaw Orthopedic, Inc. Clonidine compounds in a biodegradable fiber
HUE047629T2 (hu) 2013-01-28 2020-05-28 Lopez Hector L Eljárások ß-alanin tolerancia, farmakodinamika és hatékonyság javítására és azok alkalmazása
US20210221768A1 (en) 2018-05-14 2021-07-22 Xgene Pharmaceutical Inc. Crystalline forms of 1-(acyloxy)-alkyl carbamate drug conjugates of naproxen and pregabalin

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4087544A (en) * 1974-12-21 1978-05-02 Warner-Lambert Company Treatment of cranial dysfunctions using novel cyclic amino acids
DE2460891C2 (de) * 1974-12-21 1982-09-23 Gödecke AG, 1000 Berlin 1-Aminomethyl-1-cycloalkanessigsäuren und deren Ester, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
US5270317A (en) * 1990-03-20 1993-12-14 Elf Sanofi N-substituted heterocyclic derivatives, their preparation and the pharmaceutical compositions in which they are present
WO1993001171A1 (fr) * 1991-07-09 1993-01-21 Nippon Soda Co., Ltd. Derive de cyclohexanedione heterocyclique, production de celui-ci, et herbicide
US5514801A (en) * 1992-12-29 1996-05-07 Monsanto Company Cyclic sulfone containing retroviral protease inhibitors
GB9314758D0 (en) * 1993-07-16 1993-08-25 Wyeth John & Brother Ltd Heterocyclic derivatives
US5527194A (en) * 1994-02-02 1996-06-18 Brunswick Corporation Thrust sensor for marine drives
US5491152A (en) * 1994-03-23 1996-02-13 The Du Pont Merck Pharmaceutical Company Derivatives of cyclic ethers and sulfides for the treatment of atherosclerosis
US5760006A (en) * 1997-06-23 1998-06-02 Ortho Pharmaceutical Corporation Anticonvulsant derivatives useful in treating psoriasis

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