JP2000513351A5 - - Google Patents

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Publication number
JP2000513351A5
JP2000513351A5 JP1998502558A JP50255898A JP2000513351A5 JP 2000513351 A5 JP2000513351 A5 JP 2000513351A5 JP 1998502558 A JP1998502558 A JP 1998502558A JP 50255898 A JP50255898 A JP 50255898A JP 2000513351 A5 JP2000513351 A5 JP 2000513351A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998502558A
Other languages
English (en)
Japanese (ja)
Other versions
JP2000513351A (ja
JP4162263B2 (ja
Filing date
Publication date
Priority claimed from GBGB9613182.6A external-priority patent/GB9613182D0/en
Application filed filed Critical
Publication of JP2000513351A publication Critical patent/JP2000513351A/ja
Publication of JP2000513351A5 publication Critical patent/JP2000513351A5/ja
Application granted granted Critical
Publication of JP4162263B2 publication Critical patent/JP4162263B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP50255898A 1996-06-24 1997-06-24 フリーラジカル―誘発状態を治療するためのキレート化剤およびその金属キレート Expired - Lifetime JP4162263B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9613182.6 1996-06-24
GBGB9613182.6A GB9613182D0 (en) 1996-06-24 1996-06-24 Method
PCT/GB1997/001722 WO1997049409A1 (en) 1996-06-24 1997-06-24 Chelating agents and their metal chelates for treating free radicals induced conditions

Publications (3)

Publication Number Publication Date
JP2000513351A JP2000513351A (ja) 2000-10-10
JP2000513351A5 true JP2000513351A5 (enExample) 2005-02-10
JP4162263B2 JP4162263B2 (ja) 2008-10-08

Family

ID=10795775

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50255898A Expired - Lifetime JP4162263B2 (ja) 1996-06-24 1997-06-24 フリーラジカル―誘発状態を治療するためのキレート化剤およびその金属キレート
JP50255798A Expired - Lifetime JP4359651B2 (ja) 1996-06-24 1997-06-24 マンガン化合物を用いた抗腫瘍剤の心臓毒性の減少

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP50255798A Expired - Lifetime JP4359651B2 (ja) 1996-06-24 1997-06-24 マンガン化合物を用いた抗腫瘍剤の心臓毒性の減少

Country Status (14)

Country Link
US (2) US6147094A (enExample)
EP (2) EP0936915B1 (enExample)
JP (2) JP4162263B2 (enExample)
CN (2) CN1228703A (enExample)
AT (2) ATE225178T1 (enExample)
AU (2) AU720621B2 (enExample)
BR (1) BR9709942A (enExample)
CA (2) CA2258299A1 (enExample)
DE (2) DE69717447T2 (enExample)
GB (1) GB9613182D0 (enExample)
IL (1) IL127733A0 (enExample)
NO (2) NO985916L (enExample)
NZ (2) NZ333357A (enExample)
WO (2) WO1997049409A1 (enExample)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9727224D0 (en) * 1997-12-23 1998-02-25 Nycomed Imaging As Method
JP2001527072A (ja) 1997-12-23 2001-12-25 ニユコメド・イメージング・アクシエセルカペト 一酸化窒素を放出するキレート化剤およびその治療上の使用
KR20110049875A (ko) 1999-10-01 2011-05-12 디엠아이 바이오사이언시스, 인크 금속 결합 화합물 및 그의 용도
US7632803B2 (en) 1999-10-01 2009-12-15 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
US7592304B2 (en) 1999-10-01 2009-09-22 Dmi Life Sciences, Inc. Metal-binding compounds and uses therefor
FR2823977B1 (fr) 2001-04-26 2006-12-01 Univ Rene Descartes Utilisation du mangafodipir dans le traitement des effets d'un stress oxydatif
GB0117645D0 (en) 2001-07-19 2001-09-12 Isis Innovation Therapeutic stratergies for prevention and treatment of alzheimers disease
US20040038904A1 (en) * 2002-05-21 2004-02-26 Angela Ogden Method of treating multiple sclerosis
FR2863892B1 (fr) * 2003-12-18 2007-05-11 Univ Paris Descartes Utilisation de mimetiques de la superoxyde dismutase et de la glutathion reductase comme anti-cancereux
EP1744764B1 (en) 2004-04-22 2012-05-30 Celator Pharmaceuticals, Inc. Liposomal formulations of anthracycline agents and cytidine analogs
TR200801337T1 (tr) 2005-08-31 2008-07-21 Abraxis Bioscience, Llc. Suda zayıf çözülebilen farmasötik ajanlar ve antimikrobiyal ajanlar içeren kompozisyonlar.
KR101678866B1 (ko) * 2007-12-14 2016-11-23 플레드파르마 에이비 암의 치료에 사용하기 위한 화합물들
ES2665305T3 (es) * 2009-07-06 2018-04-25 Pledpharma Ab Composiciones farmacéuticas y métodos terapéuticos que emplean una combinación de un compuesto complejo de manganeso y una forma compleja sin manganeso del compuesto
WO2012154861A2 (en) 2011-05-09 2012-11-15 Mayo Foundation For Medical Education And Research Cancer treatments
BR112014016497B1 (pt) 2012-01-05 2021-02-23 Pledpharma Ab complexos de metal misturados, composição farmacêutica compreendendo os mesmos, métodos de produção e uso
ES2899643T3 (es) 2012-10-01 2022-03-14 Mayo Found Medical Education & Res Tratamientos para el cáncer
WO2014068514A1 (en) 2012-11-02 2014-05-08 Pledpharma Ab Cancer treatment methods
JP6695286B2 (ja) 2014-06-13 2020-05-20 メイヨ・ファウンデーション・フォー・メディカル・エデュケーション・アンド・リサーチ リンパ腫の処置
WO2015195476A1 (en) 2014-06-16 2015-12-23 Mayo Foundation For Medical Education And Research Treating myelomas
US9446148B2 (en) 2014-10-06 2016-09-20 Mayo Foundation For Medical Education And Research Carrier-antibody compositions and methods of making and using the same
TW201707725A (zh) 2015-08-18 2017-03-01 美國馬友醫藥教育研究基金會 載體-抗體組合物及其製造及使用方法
TW201713360A (en) 2015-10-06 2017-04-16 Mayo Foundation Methods of treating cancer using compositions of antibodies and carrier proteins
EP3399861A4 (en) 2016-01-07 2019-08-07 Mayo Foundation for Medical Education and Research METHOD FOR THE TREATMENT OF CANCER WITH INTERFERON
EP3413874A4 (en) 2016-02-12 2020-01-22 Mayo Foundation for Medical Education and Research TREATMENTS FOR BLOOD CANCER
AU2017238118A1 (en) 2016-03-21 2018-10-11 Mayo Foundation For Medical Education And Research Methods for improving the therapeutic index for a chemotherapeutic drug
EP3432926A4 (en) * 2016-03-21 2019-11-20 Mayo Foundation for Medical Education and Research METHOD FOR REDUCING THE TOXICITY OF CHEMOTHERAPEUTICS
US10618969B2 (en) 2016-04-06 2020-04-14 Mayo Foundation For Medical Education And Research Carrier-binding agent compositions and methods of making and using the same
JP2019526579A (ja) 2016-09-01 2019-09-19 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチMayo Foundation For Medical Education And Research T細胞癌を標的とする為の方法及び組成物
KR20220151022A (ko) 2016-09-01 2022-11-11 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 암 치료용 담체-pd-l1 결합제 조성물
EP3509635A1 (en) 2016-09-06 2019-07-17 Vavotar Life Sciences LLC Methods of treating triple-negative breast cancer using compositions of antibodies and carrier proteins
RU2756892C2 (ru) 2016-09-06 2021-10-06 Мэйо Фаундейшн Фор Медикал Эдьюкейшн Энд Рисерч Композиции с паклитакселом, альбумином и связывающим средством и способы их применения и получения
JP2019526587A (ja) 2016-09-06 2019-09-19 マヨ ファウンデーション フォー メディカル エデュケーション アンド リサーチMayo Foundation For Medical Education And Research Pd−l1を発現する癌を処置する方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES444380A1 (es) * 1976-01-16 1977-06-16 Gosalvez Mario Un procedimiento para preparar derivados metalicos antraci- clinicos.
US4935518A (en) * 1987-05-08 1990-06-19 Salutar, Inc. Manganese(II), chelate contrast agents derived from N,N'-bis-(pyridoxal ethylene diamine-N,N')-diacetic acid and derivatives thereof
US5223243A (en) * 1987-05-08 1993-06-29 Salutar, Inc. Dipyridoxyl phosphate chelating compound intermediates useful as NMRI contrast agents
US4842845A (en) * 1987-05-08 1989-06-27 Salutar, Inc. Radioactive metal chelates for dipyridoxyl phosphate
US6204259B1 (en) * 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide

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