|
EP0897986A3
(en)
*
|
1997-08-21 |
2000-07-05 |
Smithkline Beecham Corporation |
Aspartic proteinase 5 (ASP5)
|
|
US6432690B1
(en)
*
|
1998-01-16 |
2002-08-13 |
Incyte Genomics, Inc. |
Human aspartic proteases
|
|
US6203979B1
(en)
|
1998-01-16 |
2001-03-20 |
Incyte Pharmaceuticals, Inc. |
Human protease molecules
|
|
US7045333B1
(en)
|
1998-01-16 |
2006-05-16 |
Incyte Corporation |
Human protease molecules
|
|
US7160679B1
(en)
|
1998-05-21 |
2007-01-09 |
Diadexus, Inc. |
Method of diagnosing, monitoring, and staging lung cancer
|
|
AU5213199A
(en)
*
|
1998-07-16 |
2000-02-07 |
Incyte Pharmaceuticals, Inc. |
Human aspartic proteases
|
|
EP1939297A1
(en)
|
1998-09-24 |
2008-07-02 |
Pharmacia & Upjohn Company LLC |
Alzheimer's disease secretase
|
|
US7456007B1
(en)
|
1998-12-31 |
2008-11-25 |
Elan Pharmaceuticals, Inc. |
β-secretase enzyme compositions and methods
|
|
US7115410B1
(en)
*
|
1999-02-10 |
2006-10-03 |
Elan Pharmaceuticals, Inc. |
β-secretase enzyme compositions and methods
|
|
HK1044545A1
(zh)
|
1999-02-10 |
2002-10-25 |
Elan Pharmaceuticals, Inc. |
贝他分泌酶组合物及其方法
|
|
US7514408B1
(en)
|
1999-12-02 |
2009-04-07 |
Elan Pharmaceuticals, Inc. |
β-secretase enzyme compositions and methods
|
|
JP2001172200A
(ja)
*
|
1999-12-17 |
2001-06-26 |
Meneki Seibutsu Kenkyusho:Kk |
ヒトナプシンａに対する抗体およびこれを用いる医薬
|
|
AU2001252958A1
(en)
|
2000-03-23 |
2001-10-03 |
Elan Pharmaceuticals, Inc. |
Compounds and methods to treat alzheimer's disease
|
|
AU2001267548A1
(en)
*
|
2000-06-26 |
2002-01-08 |
Bayer Aktiengesellschaft |
Regulation of human napsin-like aspartyl protease
|
|
DE60116313T2
(de)
|
2000-06-30 |
2006-08-31 |
Elan Pharmaceuticals, Inc., San Francisco |
Verbindungen zur behandlung der alzheimerischen krankheit
|
|
PE20020276A1
(es)
|
2000-06-30 |
2002-04-06 |
Elan Pharm Inc |
COMPUESTOS DE AMINA SUSTITUIDA COMO INHIBIDORES DE ß-SECRETASA PARA EL TRATAMIENTO DE ALZHEIMER
|
|
EP1666452A2
(en)
|
2000-06-30 |
2006-06-07 |
Elan Pharmaceuticals, Inc. |
Compounds to treat Alzheimer's disease
|
|
US6846813B2
(en)
|
2000-06-30 |
2005-01-25 |
Pharmacia & Upjohn Company |
Compounds to treat alzheimer's disease
|
|
EP1500663A1
(en)
*
|
2000-09-28 |
2005-01-26 |
Eli Lilly And Company |
Secreted proteins and their uses
|
|
US7217556B1
(en)
|
2000-12-23 |
2007-05-15 |
Pfizer Inc |
Crystallization and structure determination of glycosylated human beta secretase, an enzyme implicated in Alzheimer's disease
|
|
US7601528B1
(en)
|
2000-12-23 |
2009-10-13 |
Elan Pharmaceuticals, Inc. |
Crystallization and structure determination of glycosylated human beta secretase, an enzyme implicated in alzheimer's disease
|
|
US7806980B2
(en)
*
|
2000-12-23 |
2010-10-05 |
Elan Pharmaceuticals, Inc. |
Method for crystallizing human beta secretase in complex with an inhibitor
|
|
US7384773B1
(en)
|
2001-05-10 |
2008-06-10 |
Pfizer Inc |
Crystal of HIV protease-cleaved human beta secretase and method for crystallization thereof
|
|
US7524668B1
(en)
*
|
2001-05-10 |
2009-04-28 |
Elan Pharmaceuticals, Inc. |
Crystal of human beta secretase having monoclinic space group symmetry C2 and methods for crystallization thereof
|
|
MXPA03011046A
(es)
|
2001-06-01 |
2004-06-25 |
Elan Pharm Inc |
Hidroxialquilaminas.
|
|
US6906104B2
(en)
|
2001-06-13 |
2005-06-14 |
Pharmacia & Upjohn Company |
Aminediols for the treatment of Alzheimer's disease
|
|
WO2003002122A1
(en)
|
2001-06-27 |
2003-01-09 |
Elan Pharmaceuticals, Inc. |
Beta-hydroxyamine derivatives useful in treatment of alzheimer's disease
|
|
MXPA04000337A
(es)
|
2001-07-10 |
2004-07-23 |
Upjohn Co |
Amindioles para tratamiento de enfermedad de alzheimer.
|
|
WO2003006013A1
(en)
|
2001-07-10 |
2003-01-23 |
Elan Pharmaceuticals, Inc. |
Diaminediols for the treatment of alzheimer's disease
|
|
US7186539B1
(en)
|
2001-08-31 |
2007-03-06 |
Pharmacia & Upjohn Company |
Method for refolding enzymes
|
|
BR0213139A
(pt)
|
2001-10-04 |
2004-08-10 |
Elan Pharm Inc |
Composto, método de tratamento ou prevenção de doenças e de preparação de um composto, uso de um composto e composição farmacêutica
|
|
EP1453789A2
(en)
|
2001-11-08 |
2004-09-08 |
Elan Pharmaceuticals, Inc. |
N,n'-substituted-1,3-diamino-2-hydroxypropane derivatives
|
|
EP1572904B1
(en)
|
2002-02-21 |
2009-04-15 |
Pharmacia & Upjohn Company LLC |
Modified bace
|
|
WO2004058686A1
(en)
|
2002-04-30 |
2004-07-15 |
Elan Pharmaceuticals, Inc. |
Hydroxypropyl amides for the treatment of alzheimer’s disease
|
|
US7442537B1
(en)
|
2002-05-10 |
2008-10-28 |
Elan Pharmaceuticals, Inc. |
Crystals of unliganded beta secretase and/or beta secretase-like proteins and the use thereof
|
|
AU2003268023A1
(en)
*
|
2002-07-23 |
2004-02-09 |
Incyte Corporation |
Protein modification and maintenance molecules
|
|
WO2004050609A1
(en)
|
2002-11-27 |
2004-06-17 |
Elan Pharmaceutical, Inc. |
Substituted ureas and carbamates
|
|
CA2523232A1
(en)
|
2003-04-21 |
2004-11-04 |
Elan Pharmaceuticals, Inc. |
(hetero) arylamide 2-hydroxy-3-diaminoalkanes for use in the treatment of alzheimer's disease
|
|
EP1473362A1
(en)
|
2003-05-02 |
2004-11-03 |
Elan Pharmaceuticals, Inc. |
Glycosylation variants of BACE
|
|
WO2005044977A2
(en)
*
|
2003-06-25 |
2005-05-19 |
Diadexus, Inc. |
Compositions, splice variants and methods relating to lung specific genes and proteins
|
|
CA2558034A1
(en)
|
2004-03-09 |
2005-09-22 |
Elan Pharmaceuticals, Inc. |
Substituted hydroxyethylamine aspartyl protease inhibitors
|
|
US20070292346A1
(en)
*
|
2004-03-25 |
2007-12-20 |
Rong Fan |
Lng105 Antibody Composition and Methods of Use, and Use of Lng105 to Assess Lung Cancer Risk
|
|
US7385085B2
(en)
|
2004-07-09 |
2008-06-10 |
Elan Pharmaceuticals, Inc. |
Oxime derivative substituted hydroxyethylamine aspartyl protease inhibitors
|
|
WO2007047305A1
(en)
|
2005-10-12 |
2007-04-26 |
Elan Pharmaceuticals, Inc. |
Methods of treating amyloidosis using cyclopropyl derivative aspartyl protease inhibitors
|
|
WO2009007300A2
(en)
|
2007-07-06 |
2009-01-15 |
Boehringer Ingelheim International Gmbh |
Substituted amino-quinazolinones, medicaments comprising said compound, their use and their method of manufacture
|