|
US5739313A
(en)
|
1995-11-13 |
1998-04-14 |
Regents Of The University Of Minnesota |
Radionuclide labeling of vitamin B12 and coenzymes thereof
|
|
KR20020032421A
(ko)
*
|
1999-04-16 |
2002-05-03 |
메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 |
항암제로서 유용한 코발라민 컨쥬게이트
|
|
US6806363B1
(en)
*
|
1999-04-16 |
2004-10-19 |
Mayo Foundation For Medical Education & Research |
Cobalamin conjugates useful as antitumor agents
|
|
JP2003512338A
(ja)
*
|
1999-10-15 |
2003-04-02 |
メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ |
造影剤および抗腫瘍薬として有用なコバラミン結合体
|
|
WO2001028595A1
(en)
*
|
1999-10-15 |
2001-04-26 |
Mayo Foundation For Medical Education And Research |
Cobalamin conjugates useful as imaging and therapeutic agents
|
|
US7591995B2
(en)
*
|
1999-10-15 |
2009-09-22 |
Mayo Foundation For Medical Education And Research |
Cobalamin conjugates useful as imaging and therapeutic agents
|
|
US7067111B1
(en)
|
1999-10-25 |
2006-06-27 |
Board Of Regents, University Of Texas System |
Ethylenedicysteine (EC)-drug conjugates, compositions and methods for tissue specific disease imaging
|
|
US6797521B2
(en)
|
1999-10-26 |
2004-09-28 |
University Of Utah Research Foundation |
Fluorescent cobalamins and uses thereof
|
|
DE10012120A1
(de)
*
|
2000-03-13 |
2001-09-27 |
Ktb Tumorforschungs Gmbh |
Therapeutische und diagnostische Ligandensysteme mit Transportmolekülbindenden Eigenschaften und diese enthaltende Arzneimittel
|
|
AU6972901A
(en)
*
|
2000-05-31 |
2001-12-11 |
Mayo Foundation |
Cobalamin compounds useful as cardiovascular agents and as imaging agents
|
|
WO2001092288A2
(en)
*
|
2000-05-31 |
2001-12-06 |
Mayo Foundation For Medical Education And Research |
Cobalamin compounds useful as antibiotic agents and as imaging agents
|
|
ES2518926T3
(es)
|
2000-06-02 |
2014-11-05 |
Board Of Regents, The University Of Texas System |
Conjugados de etilendicisteína y un análogo de glucosa
|
|
EP1754712A3
(en)
*
|
2000-10-25 |
2009-01-14 |
Mayo Foundation For Medical Education And Research |
Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
|
|
CA2427146A1
(en)
|
2000-10-25 |
2002-07-18 |
Mayo Foundation For Medical Education And Research |
Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
|
|
MXPA03004546A
(es)
*
|
2000-11-22 |
2003-09-10 |
Rxkinetix Inc |
Tratamiento de mucositis.
|
|
US20030003114A1
(en)
*
|
2001-03-22 |
2003-01-02 |
Pan Xing Qing |
Enzyme-based anti-cancer compositions and methods
|
|
US6752986B2
(en)
*
|
2001-05-24 |
2004-06-22 |
The Cleveland Clinic Foundation |
Composition and methods for affecting metallocorrinoid uptake
|
|
US20030031627A1
(en)
*
|
2001-07-31 |
2003-02-13 |
Mallinckrodt Inc. |
Internal image antibodies for optical imaging and therapy
|
|
JP2005508332A
(ja)
*
|
2001-09-28 |
2005-03-31 |
メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ |
薬剤を送達するための、輸送タンパク質とコンジュゲートコバラミンとの同時投与
|
|
US6679827B2
(en)
|
2001-10-11 |
2004-01-20 |
Robert E. Sandstrom |
Magnetic field enhancement of tumor treatment
|
|
US9657294B2
(en)
|
2002-02-20 |
2017-05-23 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of gene expression using chemically modified short interfering nucleic acid (siNA)
|
|
US20040047917A1
(en)
*
|
2002-09-06 |
2004-03-11 |
Stephen Wilson |
Drug delivery and targeting with vitamin B12 conjugates
|
|
US7627373B2
(en)
|
2002-11-30 |
2009-12-01 |
Cardiac Pacemakers, Inc. |
Method and apparatus for cell and electrical therapy of living tissue
|
|
AU2004213029A1
(en)
*
|
2003-02-20 |
2004-09-02 |
The Cleveland Clinic Foundation |
Composition and methods for inhibiting cell survival
|
|
US7232805B2
(en)
|
2003-09-10 |
2007-06-19 |
Inflabloc Pharmaceuticals, Inc. |
Cobalamin conjugates for anti-tumor therapy
|
|
US7119065B2
(en)
*
|
2003-10-29 |
2006-10-10 |
Nagoya Industrial Science Research Institute |
Metal complex-protein composite and oxidation catalyst
|
|
US9050378B2
(en)
|
2003-12-10 |
2015-06-09 |
Board Of Regents, The University Of Texas System |
N2S2 chelate-targeting ligand conjugates
|
|
US7840263B2
(en)
|
2004-02-27 |
2010-11-23 |
Cardiac Pacemakers, Inc. |
Method and apparatus for device controlled gene expression
|
|
US7764995B2
(en)
|
2004-06-07 |
2010-07-27 |
Cardiac Pacemakers, Inc. |
Method and apparatus to modulate cellular regeneration post myocardial infarct
|
|
US7729761B2
(en)
*
|
2004-07-14 |
2010-06-01 |
Cardiac Pacemakers, Inc. |
Method and apparatus for controlled gene or protein delivery
|
|
JP5149620B2
(ja)
|
2004-07-23 |
2013-02-20 |
エンドサイト，インコーポレイテッド |
２価リンカーおよびその結合体
|
|
CA2623215A1
(en)
*
|
2004-09-23 |
2006-12-28 |
The Regents Of The University Of California |
Assay for vitamin b12 absorption and method of making labeled vitamin b12
|
|
US8060219B2
(en)
|
2004-12-20 |
2011-11-15 |
Cardiac Pacemakers, Inc. |
Epicardial patch including isolated extracellular matrix with pacing electrodes
|
|
US7981065B2
(en)
|
2004-12-20 |
2011-07-19 |
Cardiac Pacemakers, Inc. |
Lead electrode incorporating extracellular matrix
|
|
US8535750B2
(en)
*
|
2005-05-17 |
2013-09-17 |
Cargill, Incorporated |
Granular lecithins, granular lysolecithins, process for their production and compositions containing them
|
|
AU2006279304A1
(en)
*
|
2005-08-19 |
2007-02-22 |
Endocyte, Inc. |
Multi-drug ligand conjugates
|
|
US7774057B2
(en)
|
2005-09-06 |
2010-08-10 |
Cardiac Pacemakers, Inc. |
Method and apparatus for device controlled gene expression for cardiac protection
|
|
WO2007064755A2
(en)
*
|
2005-11-30 |
2007-06-07 |
Endo Pharmaceuticals Inc. |
Treatment of xerostomia with a sulfur-containing antioxidant
|
|
US10925977B2
(en)
|
2006-10-05 |
2021-02-23 |
Ceil>Point, LLC |
Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
|
|
WO2008101231A2
(en)
|
2007-02-16 |
2008-08-21 |
Endocyte, Inc. |
Methods and compositions for treating and diagnosing kidney disease
|
|
AU2008223431B2
(en)
|
2007-03-05 |
2013-06-13 |
Syracuse University |
A conjugate of insulin and vitamin B12 for oral delivery
|
|
CN104127878A
(zh)
|
2007-03-14 |
2014-11-05 |
恩多塞特公司 |
结合配体连接的微管溶素递药缀合物
|
|
US20080233135A1
(en)
*
|
2007-03-19 |
2008-09-25 |
Gebhard John R |
Cobalamin taxane bioconjugates
|
|
JP5634862B2
(ja)
|
2007-05-16 |
2014-12-03 |
カーテーベー トゥモーアフォルシュングス ゲゼルシャフト ミット ベシュレンクテル ハフツング |
低粘度アントラサイクリン製剤
|
|
BRPI0812970A2
(pt)
|
2007-06-25 |
2019-09-24 |
Endocyte Inc |
conjugados contendo espaçadores hidrofílicos
|
|
US9877965B2
(en)
|
2007-06-25 |
2018-01-30 |
Endocyte, Inc. |
Vitamin receptor drug delivery conjugates for treating inflammation
|
|
US8529426B2
(en)
*
|
2007-10-18 |
2013-09-10 |
The Invention Science Fund I Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
US8227204B2
(en)
*
|
2007-10-18 |
2012-07-24 |
The Invention Science Fund I, Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
US8684898B2
(en)
*
|
2007-10-18 |
2014-04-01 |
The Invention Science Fund I Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
US8164074B2
(en)
*
|
2007-10-18 |
2012-04-24 |
The Invention Science Fund I, Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
GB2453860B
(en)
|
2007-10-18 |
2011-03-16 |
Searete Llc |
Ionizing-radiation-responsive compositions,methods and systems
|
|
US9557635B2
(en)
|
2007-10-18 |
2017-01-31 |
Gearbox, Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
US20090104113A1
(en)
*
|
2007-10-18 |
2009-04-23 |
Searete Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
US8168958B2
(en)
*
|
2007-10-18 |
2012-05-01 |
The Invention Science Fund I, Llc |
Ionizing-radiation-responsive compositions, methods, and systems
|
|
US20090169484A1
(en)
|
2007-12-28 |
2009-07-02 |
Ihi Corporation |
Iron-salen complex
|
|
JP2009274962A
(ja)
*
|
2008-05-12 |
2009-11-26 |
Yoshihiro Ishikawa |
鉄サレン錯体、磁性を有する薬剤、薬剤の誘導システム、並びに磁気検出装置
|
|
WO2010011662A1
(en)
*
|
2008-07-21 |
2010-01-28 |
Inflabloc Pharmaceuticals, Inc. |
Taxane compounds for treating eye disease
|
|
JP5513405B2
(ja)
*
|
2008-11-20 |
2014-06-04 |
株式会社Ｉｈｉ |
自己磁性金属サレン錯体化合物
|
|
WO2011125331A1
(ja)
*
|
2010-04-06 |
2011-10-13 |
株式会社Ihi |
金属サレン錯体誘導体及びその製造方法
|
|
WO2011130716A2
(en)
|
2010-04-16 |
2011-10-20 |
Access Pharmaceuticals, Inc. |
A nanostructures containing vitamin b12 for facilitated delivery of drugs across biological barriers
|
|
KR20140026396A
(ko)
|
2011-03-08 |
2014-03-05 |
어섹스 팔마큐티칼스 인코포레이티드 |
생물학적 막을 가로질러 활성물질의 전달을 위한 표적화된 나노담체 시스템
|
|
US10080805B2
(en)
|
2012-02-24 |
2018-09-25 |
Purdue Research Foundation |
Cholecystokinin B receptor targeting for imaging and therapy
|
|
US20140080175A1
(en)
|
2012-03-29 |
2014-03-20 |
Endocyte, Inc. |
Processes for preparing tubulysin derivatives and conjugates thereof
|
|
EP2908818A4
(en)
|
2012-10-16 |
2016-07-13 |
Endocyte Inc |
CONJUGATES OF DRUG DELIVERY CONTAINING ARTIFICIAL AMINO ACIDS AND METHODS OF USE
|
|
US9352049B2
(en)
|
2013-03-14 |
2016-05-31 |
Albany Molecular Research, Inc. |
Ligand-therapeutic agent conjugates, silicon-based linkers, and methods for making and using them
|
|
CN105307663A
(zh)
*
|
2013-04-08 |
2016-02-03 |
北卡罗来纳大学教堂山分校 |
光响应化合物
|
|
TW201936624A
(zh)
*
|
2013-05-22 |
2019-09-16 |
美商阿尼拉製藥公司 |
絲胺酸蛋白酶抑制因子Ａ１ ｉＲＮＡ組成物及其使用方法
|
|
CN111437395A
(zh)
*
|
2013-08-29 |
2020-07-24 |
希望之城 |
细胞穿透缀合物及其使用方法
|
|
GR20130100654A
(el)
*
|
2013-11-22 |
2015-06-18 |
Χρηστος Γκολφινου Ταπεινος |
Επιφανειακως τροποποιημενα πολλαπλως αποκρινομενα σε ερεθισματα νανο/μικρο-δοχεια ως φορεις φαρμακων για στοχευμενη θεραπεια διαφορων μορφων καρκινου
|
|
WO2020113130A1
(en)
*
|
2018-11-29 |
2020-06-04 |
The Trustees Of Dartmouth College |
Tumor targeting vitamin b12 derivatives for x-ray activated chemotherapy
|
|
GB202018713D0
(en)
|
2020-11-27 |
2021-01-13 |
Quadram Inst Bioscience |
Methods and compositions utilising vitamin b12 binding
|