JP2001500986A - 微小画像結像システム - Google Patents

微小画像結像システム

Info

Publication number
JP2001500986A
JP2001500986A JP10514777A JP51477798A JP2001500986A JP 2001500986 A JP2001500986 A JP 2001500986A JP 10514777 A JP10514777 A JP 10514777A JP 51477798 A JP51477798 A JP 51477798A JP 2001500986 A JP2001500986 A JP 2001500986A
Authority
JP
Japan
Prior art keywords
detector
lens
light
sample
optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP10514777A
Other languages
English (en)
Japanese (ja)
Other versions
JP2001500986A5 (https=
Inventor
カイン，ロバート・シィ
Original Assignee
モレキュラー・ダイナミックス・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by モレキュラー・ダイナミックス・インコーポレイテッド filed Critical モレキュラー・ダイナミックス・インコーポレイテッド
Publication of JP2001500986A publication Critical patent/JP2001500986A/ja
Publication of JP2001500986A5 publication Critical patent/JP2001500986A5/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B21/00—Microscopes
    • G02B21/02—Objectives

Landscapes

  • Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Microscoopes, Condenser (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
JP10514777A 1996-09-19 1997-09-12 微小画像結像システム Pending JP2001500986A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/716,858 1996-09-19
US08/716,858 US5754291A (en) 1996-09-19 1996-09-19 Micro-imaging system
PCT/US1997/016224 WO1998012536A1 (en) 1996-09-19 1997-09-12 Micro-imaging system

Publications (2)

Publication Number Publication Date
JP2001500986A true JP2001500986A (ja) 2001-01-23
JP2001500986A5 JP2001500986A5 (https=) 2005-08-11

Family

ID=24879741

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10514777A Pending JP2001500986A (ja) 1996-09-19 1997-09-12 微小画像結像システム

Country Status (5)

Country Link
US (1) US5754291A (https=)
EP (1) EP1015869B1 (https=)
JP (1) JP2001500986A (https=)
DE (1) DE69728572T2 (https=)
WO (1) WO1998012536A1 (https=)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002168787A (ja) * 2000-12-04 2002-06-14 Fuji Photo Film Co Ltd 画像読み取り方法および装置
JP2004537053A (ja) * 2001-07-25 2004-12-09 アプレラ コーポレイション 電気泳動検出システムにおける時間遅延積分
JP2005517217A (ja) * 2002-02-06 2005-06-09 ケーエルエー−テンカー テクノロジィース コーポレイション 複数検出器顕微鏡検査システム
JP2007093390A (ja) * 2005-09-29 2007-04-12 Tochigi Nikon Corp テラヘルツ波イメージング装置
JP2008507719A (ja) * 2004-07-23 2008-03-13 ジーイー・ヘルスケア・ナイアガラ・インク 共焦点蛍光顕微鏡法及び装置
JP2008544226A (ja) * 2005-08-08 2008-12-04 エス アール ユー バイオシステムズ，インコーポレイテッド 生体分子センサーの標的領域の画像を形成させるための方法と装置
JP2010513968A (ja) * 2006-12-22 2010-04-30 アイシス イノベイシヨン リミテツド 焦点調整装置および焦点調整方法
JP2010515019A (ja) * 2006-12-21 2010-05-06 バイオ−ラッド ラボラトリーズ，インコーポレイティド 二次元配列画像化
JP2011039071A (ja) * 1998-05-16 2011-02-24 Applied Biosystems Llc Ｄｎａのポリメラーゼ連鎖反応をモニタする装置
JPWO2022004147A1 (https=) * 2020-07-02 2022-01-06
JP2022031290A (ja) * 2015-02-06 2022-02-18 ライフ テクノロジーズ コーポレーション 生体サンプルを評価するためのシステムおよび方法
JP2022524566A (ja) * 2019-03-19 2022-05-09 オメック オプティクス エルティーディー． 単位倍率顕微鏡

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US7498164B2 (en) 1998-05-16 2009-03-03 Applied Biosystems, Llc Instrument for monitoring nucleic acid sequence amplification reaction
JP2002537667A (ja) 1998-11-25 2002-11-05 フォーマックス コーポレイション デュアルヘッド蛍光体スクリーンスキャナ
US6246046B1 (en) * 1999-01-21 2001-06-12 University Of Pittsburgh Method and apparatus for electronically controlled scanning of micro-area devices
US8885913B2 (en) 1999-01-25 2014-11-11 Amnis Corporation Detection of circulating tumor cells using imaging flow cytometry
US6249341B1 (en) * 1999-01-25 2001-06-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US7057732B2 (en) * 1999-01-25 2006-06-06 Amnis Corporation Imaging platform for nanoparticle detection applied to SPR biomolecular interaction analysis
US6608682B2 (en) 1999-01-25 2003-08-19 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US6671044B2 (en) 1999-01-25 2003-12-30 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells in broad flat flow
US20060257884A1 (en) * 2004-05-20 2006-11-16 Amnis Corporation Methods for preparing and analyzing cells having chromosomal abnormalities
US8406498B2 (en) * 1999-01-25 2013-03-26 Amnis Corporation Blood and cell analysis using an imaging flow cytometer
US6707551B2 (en) * 2000-01-24 2004-03-16 Amnis Corporation Multipass cavity for illumination and excitation of moving objects
US7450229B2 (en) * 1999-01-25 2008-11-11 Amnis Corporation Methods for analyzing inter-cellular phenomena
US6975400B2 (en) * 1999-01-25 2005-12-13 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US8131053B2 (en) 1999-01-25 2012-03-06 Amnis Corporation Detection of circulating tumor cells using imaging flow cytometry
US6473176B2 (en) 1999-01-25 2002-10-29 Amnis Corporation Imaging and analyzing parameters of small moving objects such as cells
US8005314B2 (en) * 2005-12-09 2011-08-23 Amnis Corporation Extended depth of field imaging for high speed object analysis
EP1272822A4 (en) * 2000-01-24 2008-03-12 Amnis Corp PARAMETERS FOR IMAGING AND ANALYZING SMALL MOBILE OBJECTS SUCH AS CELLS
US7738688B2 (en) 2000-05-03 2010-06-15 Aperio Technologies, Inc. System and method for viewing virtual slides
US6711283B1 (en) 2000-05-03 2004-03-23 Aperio Technologies, Inc. Fully automatic rapid microscope slide scanner
US7668362B2 (en) 2000-05-03 2010-02-23 Aperio Technologies, Inc. System and method for assessing virtual slide image quality
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US6690467B1 (en) * 2000-05-05 2004-02-10 Pe Corporation Optical system and method for optically analyzing light from a sample
JP3818867B2 (ja) * 2000-05-12 2006-09-06 リオン株式会社 光散乱式粒子検出器
DE10029680B4 (de) * 2000-06-23 2016-06-16 Leica Microsystems Cms Gmbh Mikroskop-Aufbau
US6875973B2 (en) * 2000-08-25 2005-04-05 Amnis Corporation Auto focus for a flow imaging system
US6608680B2 (en) 2000-08-25 2003-08-19 Amnis Corporation TDI imaging system for kinetic studies
US6583865B2 (en) * 2000-08-25 2003-06-24 Amnis Corporation Alternative detector configuration and mode of operation of a time delay integration particle analyzer
US6934408B2 (en) * 2000-08-25 2005-08-23 Amnis Corporation Method and apparatus for reading reporter labeled beads
US6778263B2 (en) * 2000-08-25 2004-08-17 Amnis Corporation Methods of calibrating an imaging system using calibration beads
AU2001290568A1 (en) 2000-08-25 2002-03-04 Amnis Corporation Measuring the velocity of small moving objects such as cells
US7009651B2 (en) 2000-10-12 2006-03-07 Amnis Corporation System and method for high numeric aperture imaging systems
US20020146734A1 (en) * 2001-02-21 2002-10-10 Amnis Corporation Method and apparatus for labeling and analyzing cellular components
AU2002308693A1 (en) * 2001-04-25 2002-11-05 Amnis Corporation Method and apparatus for correcting crosstalk and spatial resolution for multichannel imaging
US6716683B1 (en) * 2001-06-22 2004-04-06 Advanced Mircor Devices, Inc. Optical analysis for SOI integrated circuits
US7190832B2 (en) 2001-07-17 2007-03-13 Amnis Corporation Computational methods for the segmentation of images of objects from background in a flow imaging instrument
US7280207B2 (en) 2001-07-25 2007-10-09 Applera Corporation Time-delay integration in a flow cytometry system
US7265833B2 (en) * 2001-07-25 2007-09-04 Applera Corporation Electrophoretic system with multi-notch filter and laser excitation source
US6943572B2 (en) * 2002-09-03 2005-09-13 Credence Systems Corporation Apparatus and method for detecting photon emissions from transistors
US6891363B2 (en) * 2002-09-03 2005-05-10 Credence Systems Corporation Apparatus and method for detecting photon emissions from transistors
DE10246521B4 (de) * 2002-10-05 2005-11-10 Karl Storz Gmbh & Co. Kg Endoskop
WO2004065544A2 (en) * 2003-01-15 2004-08-05 Amnis Corporation Cell suspension rotating fluidic pump
WO2004102627A2 (en) * 2003-05-08 2004-11-25 Alara, Inc. Method and apparatus for radiation image erasure
US20040259270A1 (en) * 2003-06-19 2004-12-23 Wolf David E. System, device and method for exciting a sensor and detecting analyte
DE102004012161B3 (de) * 2004-03-12 2005-11-03 Nanofilm Technologie Gmbh Abbildendes Ellipsometer mit synchronisiertem Probenvorschub und ellipsometrisches Messverfahren
WO2005090945A1 (en) 2004-03-16 2005-09-29 Amnis Corporation Method for imaging and differential analysis of cells
US8953866B2 (en) 2004-03-16 2015-02-10 Amnis Corporation Method for imaging and differential analysis of cells
CA2598602A1 (en) 2004-03-16 2005-10-20 Amnis Corporation Image based quantitation of molecular translocation
WO2005119575A2 (en) * 2004-05-27 2005-12-15 Aperio Technologies, Inc Systems and methods for creating and viewing three dimensional virtual slides
US7768638B2 (en) * 2005-03-18 2010-08-03 Illumina, Inc. Systems for and methods of facilitating focusing an optical scanner
US8164622B2 (en) 2005-07-01 2012-04-24 Aperio Technologies, Inc. System and method for single optical axis multi-detector microscope slide scanner
US7329860B2 (en) * 2005-11-23 2008-02-12 Illumina, Inc. Confocal imaging methods and apparatus
US7791013B2 (en) * 2006-11-21 2010-09-07 Illumina, Inc. Biological microarray line scanning method and system
US7813013B2 (en) * 2006-11-21 2010-10-12 Illumina, Inc. Hexagonal site line scanning method and system
US8179526B2 (en) * 2007-01-25 2012-05-15 Renishaw Plc Spectroscopic apparatus with dispersive device for collecting sample data in synchronism with relative movement of a focus
GB0708582D0 (en) * 2007-05-03 2007-06-13 Renishaw Plc Spectroscope apparatus and methods
WO2009123767A1 (en) 2008-04-04 2009-10-08 Life Technologies Corporation Scanning system and method for imaging and sequencing
WO2010048584A2 (en) 2008-10-24 2010-04-29 Aperio Technologies, Inc. Whole slide fluorescence scanner
US8570370B2 (en) * 2009-08-31 2013-10-29 Bio-Rad Laboratories, Inc. Compact automated cell counter
US8451524B2 (en) * 2009-09-29 2013-05-28 Amnis Corporation Modifying the output of a laser to achieve a flat top in the laser's Gaussian beam intensity profile
US9280726B2 (en) 2009-12-18 2016-03-08 Fpinnovation On-line macrocontaminant analyser and method
US8817115B1 (en) 2010-05-05 2014-08-26 Amnis Corporation Spatial alignment of image data from a multichannel detector using a reference image
US9029103B2 (en) 2010-08-27 2015-05-12 Illumina Cambridge Limited Methods for sequencing polynucleotides
US8575071B2 (en) 2010-11-03 2013-11-05 Illumina, Inc. Reducing adapter dimer formation
DE102011055294B4 (de) 2011-11-11 2013-11-07 Leica Microsystems Cms Gmbh Mikroskopische Einrichtung und Verfahren zur dreidimensionalen Lokalisierung von punktförmigen Objekten in einer Probe
DE102011087454A1 (de) * 2011-11-30 2013-06-06 Leica Microsystems (Schweiz) Ag Optische Vorrichtung zum Einsatz in der Medizintechnik
WO2013117595A2 (en) 2012-02-07 2013-08-15 Illumina Cambridge Limited Targeted enrichment and amplification of nucleic acids on a support
WO2015103225A1 (en) 2013-12-31 2015-07-09 Illumina, Inc. Addressable flow cell using patterned electrodes
US10766242B2 (en) * 2017-08-24 2020-09-08 General Electric Company System and methods for fabricating a component using a consolidating device
JP7542444B2 (ja) 2018-12-14 2024-08-30 イルミナ ケンブリッジ リミテッド 配列決定の間のアンラベル化ヌクレオチドによるフェージング減少
ES3032918T3 (en) 2018-12-17 2025-07-28 Illumina Cambridge Ltd Method of polynucleotide sequencing
CN112654714B (zh) 2018-12-17 2024-10-11 伊卢米纳剑桥有限公司 用于测序的引物寡核苷酸
US12480157B2 (en) 2021-09-30 2025-11-25 Illumina, Inc. Polynucleotide sequencing
US20250215491A1 (en) 2023-12-28 2025-07-03 Illumina, Inc. Sequencing with single-stranded binding proteins

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JPH03221912A (ja) * 1990-01-29 1991-09-30 Fuji Photo Film Co Ltd 走査型顕微鏡における撮像方法
JPH08152404A (ja) * 1994-11-29 1996-06-11 Toray Ind Inc 光学定数測定方法およびその装置
JPH08160306A (ja) * 1994-12-02 1996-06-21 Keyence Corp 光学顕微鏡

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JPH08152404A (ja) * 1994-11-29 1996-06-11 Toray Ind Inc 光学定数測定方法およびその装置
JPH08160306A (ja) * 1994-12-02 1996-06-21 Keyence Corp 光学顕微鏡

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011039071A (ja) * 1998-05-16 2011-02-24 Applied Biosystems Llc Ｄｎａのポリメラーゼ連鎖反応をモニタする装置
JP2002168787A (ja) * 2000-12-04 2002-06-14 Fuji Photo Film Co Ltd 画像読み取り方法および装置
JP2004537053A (ja) * 2001-07-25 2004-12-09 アプレラ コーポレイション 電気泳動検出システムにおける時間遅延積分
JP2005517217A (ja) * 2002-02-06 2005-06-09 ケーエルエー−テンカー テクノロジィース コーポレイション 複数検出器顕微鏡検査システム
JP2008507719A (ja) * 2004-07-23 2008-03-13 ジーイー・ヘルスケア・ナイアガラ・インク 共焦点蛍光顕微鏡法及び装置
JP4866903B2 (ja) * 2005-08-08 2012-02-01 エス アール ユー バイオシステムズ，インコーポレイテッド 生体分子センサーの標的領域の画像を形成させるための方法と装置
JP2008544226A (ja) * 2005-08-08 2008-12-04 エス アール ユー バイオシステムズ，インコーポレイテッド 生体分子センサーの標的領域の画像を形成させるための方法と装置
JP2007093390A (ja) * 2005-09-29 2007-04-12 Tochigi Nikon Corp テラヘルツ波イメージング装置
JP2010515019A (ja) * 2006-12-21 2010-05-06 バイオ−ラッド ラボラトリーズ，インコーポレイティド 二次元配列画像化
JP2013061688A (ja) * 2006-12-22 2013-04-04 Isis Innovation Ltd 焦点調整装置および焦点調整方法
JP2014095908A (ja) * 2006-12-22 2014-05-22 Isis Innovation Ltd 焦点調整装置および焦点調整方法
US9638909B2 (en) 2006-12-22 2017-05-02 Isis Innovation Limited Focusing apparatus and method
JP2010513968A (ja) * 2006-12-22 2010-04-30 アイシス イノベイシヨン リミテツド 焦点調整装置および焦点調整方法
JP2023099589A (ja) * 2015-02-06 2023-07-13 ライフ テクノロジーズ コーポレーション 生体サンプルを評価するためのシステムおよび方法
JP7641319B2 (ja) 2015-02-06 2025-03-06 ライフ テクノロジーズ コーポレーション 生体サンプルを評価するためのシステムおよび方法
JP2022031290A (ja) * 2015-02-06 2022-02-18 ライフ テクノロジーズ コーポレーション 生体サンプルを評価するためのシステムおよび方法
JP7389095B2 (ja) 2015-02-06 2023-11-29 ライフ テクノロジーズ コーポレーション 生体サンプルを評価するためのシステムおよび方法
JP7432946B2 (ja) 2019-03-19 2024-02-19 オメック オプティクス エルティーディー． 単位倍率顕微鏡
JP2022524566A (ja) * 2019-03-19 2022-05-09 オメック オプティクス エルティーディー． 単位倍率顕微鏡
WO2022004147A1 (ja) * 2020-07-02 2022-01-06 コニカミノルタ株式会社 光学特性測定光学系および光学特性測定装置
JPWO2022004147A1 (https=) * 2020-07-02 2022-01-06
JP2025063237A (ja) * 2020-07-02 2025-04-15 コニカミノルタ株式会社 光学特性測定光学系および光学特性測定装置
JP7708341B2 (ja) 2020-07-02 2025-07-15 コニカミノルタ株式会社 光学特性測定光学系および光学特性測定装置

Also Published As

Publication number Publication date
EP1015869B1 (en) 2004-04-07
US5754291A (en) 1998-05-19
WO1998012536A1 (en) 1998-03-26
DE69728572D1 (de) 2004-05-13
DE69728572T2 (de) 2005-03-03
EP1015869A4 (en) 2000-07-05
EP1015869A1 (en) 2000-07-05

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