|
TW530054B
(en)
|
1997-09-24 |
2003-05-01 |
Duphar Int Res |
New piperazine and piperidine compounds
|
|
CO5011067A1
(es)
*
|
1997-11-03 |
2001-02-28 |
Novartis Ag |
Derivados de bifenilo como productos farmaceuticos, su pre- paracion y composiciones farmaceuticas que los contienen
|
|
USRE46117E1
(en)
|
1999-12-22 |
2016-08-23 |
Teva Pharmaceuticals International Gmbh |
Modulators of dopamine neurotransmission
|
|
SE9904724D0
(sv)
*
|
1999-12-22 |
1999-12-22 |
Carlsson A Research Ab |
New modulators of dopamine neurotransmission I
|
|
SE9904723D0
(sv)
*
|
1999-12-22 |
1999-12-22 |
Carlsson A Research Ab |
New modulators of dopamine neurotransmission II
|
|
EP1333832B1
(en)
*
|
2000-11-14 |
2007-11-28 |
MERCK PATENT GmbH |
Novel uses of combined 5-ht1a agonists and serotonin reuptake inhibitors
|
|
KR100394086B1
(ko)
*
|
2000-12-04 |
2003-08-06 |
한국과학기술연구원 |
도파민 ｄ3 및 ｄ4 수용체의 선택적 활성을 지닌 신규이소옥사졸릴알킬피페라진 유도체와, 이의 제조방법
|
|
KR100394083B1
(ko)
*
|
2000-12-04 |
2003-08-06 |
학교법인 성신학원 |
도파민 ｄ3 및 ｄ4 수용체의 선택적 활성을 지닌 신규4,5-디히드로이소옥사졸릴알킬피페라진 유도체와, 이의제조방법
|
|
EP1935885A3
(en)
*
|
2001-05-22 |
2008-10-15 |
Neurogen Corporation |
Melanin concentrating hormone receptor ligands : substituted 1-benzyl-4-aryl piperazine analogues.
|
|
IL158941A0
(en)
|
2001-05-22 |
2004-05-12 |
Neurogen Corp |
Melanin concentrating hormone receptor ligands: substituted 1-benzyl-4-aryl piperazine analogues
|
|
US6432957B1
(en)
*
|
2001-06-29 |
2002-08-13 |
Kowa Co., Ltd. |
Piperazine derivative
|
|
US6552188B2
(en)
*
|
2001-06-29 |
2003-04-22 |
Kowa Co., Ltd. |
Unsymmetrical cyclic diamine compound
|
|
US6509329B1
(en)
*
|
2001-06-29 |
2003-01-21 |
Kowa Co., Ltd. |
Cyclic diamine compound with 6-membered ring groups
|
|
CN1172919C
(zh)
|
2002-06-03 |
2004-10-27 |
上海医药工业研究院 |
芳烷醇哌嗪衍生物及其在制备抗抑郁症药物中的应用
|
|
CA2517081A1
(en)
*
|
2003-03-07 |
2004-09-16 |
Astellas Pharma Inc. |
Nitrogen-containing heterocyclic derivatives having 2-6, disubtituted styryl
|
|
JP4596792B2
(ja)
*
|
2004-02-24 |
2010-12-15 |
あすか製薬株式会社 |
５−ｈｔ１ａ作動作用と５−ｈｔ３拮抗作用を併有する薬剤
|
|
JP2008501749A
(ja)
|
2004-06-08 |
2008-01-24 |
ニューロサーチ スウェーデン アクチボラゲット |
ドーパミン及びセロトニン神経伝達のモジュレーターとしての新規なジ置換フェニルピペリジン
|
|
SE0401465D0
(sv)
|
2004-06-08 |
2004-06-08 |
Carlsson A Research Ab |
New substituted piperdines as modulators of dopamine neurotransmission
|
|
DE602005021641D1
(de)
|
2004-06-08 |
2010-07-15 |
Nsab, Filial Af Neurosearch Sweden Ab |
Neue disubstituierte phenylpiperidine und piperazine als modulatoren der dopamin-neurotransmission
|
|
US7851629B2
(en)
|
2004-06-08 |
2010-12-14 |
Nsab, Filial Af Neurosearch Sweden Ab, Sverige |
Disubstituted phenylpiperidines as modulators of dopamine and serotonin neurotransmission
|
|
CA2584831C
(en)
|
2004-10-13 |
2013-09-17 |
Neurosearch Sweden Ab |
Process for the synthesis of 4-(3-methanesulfonylphenyl)-1-n-propyl-piperidine
|
|
EP1695971A1
(en)
*
|
2004-12-30 |
2006-08-30 |
Laboratorios Del Dr. Esteve, S.A. |
Substituted phenyl-piperazine compounds, their preparation and use in medicaments
|
|
SE529246C2
(sv)
|
2005-10-13 |
2007-06-12 |
Neurosearch Sweden Ab |
Nya disubstituerade fenyl-piperidiner som modulatorer för dopaminneurotransmission
|
|
WO2008047839A1
(en)
*
|
2006-10-19 |
2008-04-24 |
Dainippon Sumitomo Pharma Co., Ltd. |
5-ht1a receptor agonist
|
|
JO2857B1
(en)
*
|
2008-06-16 |
2015-03-15 |
سانوفي أفينتس |
Vinyl pipers with modified activity of tumor-resistant TNF
|
|
US8673920B2
(en)
|
2009-05-06 |
2014-03-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US8609672B2
(en)
|
2010-08-27 |
2013-12-17 |
University Of The Pacific |
Piperazinylpyrimidine analogues as protein kinase inhibitors
|
|
WO2012058116A1
(en)
|
2010-10-27 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2632464B1
(en)
|
2010-10-29 |
2015-04-29 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
RU2448962C1
(ru)
*
|
2011-02-08 |
2012-04-27 |
Государственное образовательное учреждение высшего профессионального образования "Ярославский государственный университет им. П.Г. Демидова" |
Способ получения 1,4-бис(2-амино-4-(трифторметил)фенил)пиперазина
|
|
AU2012299227A1
(en)
|
2011-08-19 |
2014-02-20 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2013039802A1
(en)
|
2011-09-16 |
2013-03-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US8999990B2
(en)
|
2011-10-25 |
2015-04-07 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2771004B1
(en)
|
2011-10-25 |
2016-05-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2013066714A1
(en)
|
2011-10-31 |
2013-05-10 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2773206B1
(en)
|
2011-10-31 |
2018-02-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2773351B1
(en)
|
2011-10-31 |
2017-08-23 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
MX347209B
(es)
|
2011-12-08 |
2017-04-19 |
Teva Pharmaceuticals Int Gmbh |
La sal de bromhidrato de pridopidina.
|
|
EP2790511B1
(en)
|
2011-12-16 |
2016-09-14 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
HK1206297A1
(en)
|
2012-04-04 |
2016-01-08 |
Teva Pharmaceuticals International Gmbh |
Pharmaceutical compositions for combination therapy
|
|
WO2013161643A1
(ja)
|
2012-04-27 |
2013-10-31 |
吉野石膏株式会社 |
石膏系鋳造用埋没材組成物
|
|
US9718121B2
(en)
|
2012-06-18 |
2017-08-01 |
Yoshino Gypsum Co., Ltd. |
Casting investment composition and casting process using same
|
|
AR092031A1
(es)
|
2012-07-26 |
2015-03-18 |
Merck Sharp & Dohme |
Inhibidores del canal de potasio medular externo renal
|
|
EP2925322B1
(en)
|
2012-11-29 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
US9573961B2
(en)
|
2012-12-19 |
2017-02-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
RU2505536C1
(ru)
*
|
2012-12-29 |
2014-01-27 |
Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Ярославский государственный технический университет" |
4-(1-гидрокси-1-метил-2-морфолиноэтил)бензойная и 4-(1-гидрокси-2-морфолиноциклогексил)бензойная кислоты, их фармацевтически приемлемые соли, сложные эфиры, обладающие анксиолитической активностью, и способ их получения
|
|
US8883796B2
(en)
*
|
2013-02-08 |
2014-11-11 |
Korea Institute Of Science And Technology |
Biphenyl derivatives, pharmaceutical composition comprising the same, and preparation method thereof
|
|
WO2014126944A2
(en)
|
2013-02-18 |
2014-08-21 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP2968288B1
(en)
|
2013-03-15 |
2018-07-04 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
EP3027625B1
(en)
|
2013-07-31 |
2018-05-30 |
Merck Sharp & Dohme Corp. |
Spiro-fused derivatives of piperidine useful for the treatment of inter alia hypertension and acute or chronic heart failure
|
|
WO2015065866A1
(en)
|
2013-10-31 |
2015-05-07 |
Merck Sharp & Dohme Corp. |
Inhibitors of the renal outer medullary potassium channel
|
|
WO2016127358A1
(en)
|
2015-02-12 |
2016-08-18 |
Merck Sharp & Dohme Corp. |
Inhibitors of renal outer medullary potassium channel
|
|
WO2018089493A1
(en)
*
|
2016-11-08 |
2018-05-17 |
Navitor Pharmaceuticals, Inc. |
PYRROLE mTORC INHIBITORS AND USES THEREOF
|