JP2001253808A - Hair growing cosmetic - Google Patents

Abstract

PROBLEM TO BE SOLVED: To obtain a hair growing cosmetic which exhibits excellent hair growing effect and depilation prophylactic effect. SOLUTION: This hair growing cosmetic features including an extract extracted from fruits of acerola and at least one kind of substances selected from the group consisting of swertia herb extract, ginseng extract, capsicum tincture, hinokitiol, vitamin E and its derivatives, pantothenic acid derivatives, nicotinic acid derivatives, glycyrrhezinic acid and its derivatives or glycrrhetinic acid and its derivatives.

Description

DETAILED DESCRIPTION OF THE INVENTION

[0001]

BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates to a hair nourishing cosmetic having an excellent hair-growth effect and an effect of preventing hair loss.

[0002]

2. Description of the Related Art Conventionally, hair restoration cosmetics containing a blood circulation promoting substance such as pepper tincture and nicotinic acid derivative, and amino acids and vitamins which are nutrients of hair are known. Have been.
Further, many medical hair restorers and cosmetics containing a component having an effect of preventing sebaceous gland hypertrophy and a component having an androgenic inhibitory effect have been proposed.

[0003] However, conventionally used blood circulation promoting substances are highly irritating to the skin, and the amount thereof is limited,
The disadvantage is that the duration of blood circulation promotion is short. In addition, there is also a problem that the hair nutrient has low permeability to the skin at a low concentration, and its effect is not sufficiently exhibited by itself.

[0004] By the way, androgenetic alopecia is said to be one of the causes of the excessive action of male hormones. Phenomena such as poor circulation, decreased activity of hair matrix cells, enlargement of sebaceous glands, fibrosis of the scalp, and the like are considered. It is presumed that it is caused by complicated intertwining.

[0005] However, even if an anti-androgen agent is simply used as a hair restorer to suppress hair matrix cell activity reduction and sebaceous gland hypertrophy, which are said to be caused by excessive action of androgen, the hair growth effect is exhibited. At present it does not reach. In addition, good results cannot be obtained even when the hair matrix activator or the blood circulation promoter is used alone.

As a means for solving the above-mentioned problems, a hair restorer composition containing fatty acids and alcohols having an odd carbon number, hydroxypropyl alcohol and a lower alcohol disclosed in JP-A-5-58850 is disclosed. Numerous hair growth and hair growth, such as a hair growth agent containing certain carboxybetaines in JP-A-5-139936 and a hair growth cosmetic containing an acid mucopolysaccharide and a hop extract in JP-A-5-170625. Agents have been proposed, but using a substance that promotes peripheral blood flow and activates hair matrix cells alone has not found any remarkable hair-growth effect, and has a satisfactory effect in the composition. In fact, there was room for improvement in the hair growth effect and the hair loss prevention effect.

[0007]

Means for Solving the Problems In view of such circumstances, the present inventors have conducted intensive studies on substances that promote peripheral blood flow of the scalp and activate hair matrix cells.
Extracts extracted from the fruits of acerola, and extracts from the group consisting of assembly extract, Korean ginseng extract, pepper tincture, hinokitiol, vitamin E and its derivatives, pantothenic acid derivatives, nicotinic acid derivatives, glycyrrhizic acid and its derivatives, glycyrrhetinic acid and its derivatives The present inventors have found that a hair-growing cosmetic containing at least one or more selected substances exhibits excellent hair-growth effects and hair-loss-preventing effects, which are the objects of the present invention, due to the synergistic effect of each component, and completed the present invention.

[0008] More specifically, an extract extracted from the fruit of acerola, an assembly extract, a Korean ginseng extract, a red pepper tincture, hinokitiol, vitamin E and its derivatives, pantothenic acid derivatives, nicotinic acid derivatives, glycyrrhizic acid and its derivatives, glycyrrhetinic acid and its The object of the present invention is achieved by a hair growth cosmetic containing at least one substance selected from the group consisting of derivatives.

[0009]

Embodiments of the present invention will be described below in detail.

[0010] Acerola (Malpighia glabra Linne) is an evergreen shrub native to Latin America that bears small red berries similar to cherries. This fruit contains a large amount of L-ascorbic acid and is used as a food material.

[0011] The extract extracted from the fruit of acerola used in the present invention is produced by the method disclosed in Japanese Patent Application Laid-Open No. 2-200610 and the like, and in addition to L-ascorbic acid, amino acids, organic acids, sugars, It also contains useful substances such as pectin. It is well known that an extract extracted from this acerola fruit is incorporated into cosmetics (Japanese Patent Laid-Open No. 2-2 / 1990).
No. 6010). However, the effect on hair growth cosmetics is not known at present.

The following is an example of a method for extracting an extract from the fruit of acerola. <Extraction Example 1> Acerola fruits are washed with water and pressed to obtain a pressed juice. The precipitate is removed by filtration, decantation or the like, and concentrated under reduced pressure as necessary. Thereafter, if necessary, ethanol, propylene glycol and the like are added, and the mixture is allowed to stand at a low temperature. Thereafter, the formed precipitate is removed by filtration again, and if necessary, an extract is obtained by filtration using a membrane filter having a pore size of 0.22 μm.

<Extraction Example 2> Acerola fruit is finely pulverized, and glycerin, 1,3-butylene glycol, propylene glycol, ethanol, water, etc. are used alone or as a mixture as an extraction solvent. Extract by immersion. The extract is concentrated under reduced pressure as necessary, filtered,
The extract is clarified by decantation or the like, and if necessary, filtered using a membrane filter having a pore size of 0.22 μm to obtain an extract.

<Extraction Example 3> The extract obtained in Extraction Example 1 or 2 is re-extracted with another solvent. Thereafter, if necessary, the extract is obtained by filtration using a membrane filter having a pore size of 0.22 μm. By selecting a solvent, it is possible to remove some components, and it is possible to obtain an extract suitable for blending into a hair nourishing cosmetic.

The scope of the present invention, which shows a hair-growth effect and a hair-loss preventing effect, was examined. As a result, the blending amount of the extract extracted from the fruit of the acerola according to the present invention obtained by the above method was 0.001% of the hair restoration cosmetic when the mass ratio of the fruit used for the extraction and the obtained extract was 1. It is sufficient if it is -20 mass% (hereinafter abbreviated as wt%), and more preferably 0.01-10 wt%.

Vitamin E and its derivatives used in the present invention are known compounds, and vitamin E, vitamin E acetate and vitamin E nicotinate are particularly preferred, but are not limited thereto.

The pantothenic acid derivative used in the present invention is a known compound, and pantothenyl alcohol and calcium pantothenate can be mentioned as particularly preferable ones, but are not limited thereto.

The nicotinic acid derivative used in the present invention is a known compound, and benzyl nicotinate and nicotinamide can be mentioned as particularly preferable ones, but are not limited thereto.

Glycyrrhizic acid and its derivatives used in the present invention are known compounds, and glycyrrhizic acid, dipotassium glycyrrhizinate and monoammonium glycyrrhizinate can be mentioned as particularly preferable ones, but are not limited thereto.

Glycyrrhetinic acid and its derivatives used in the present invention are known compounds, and glycyrrhetinic acid and stearyl glycyrrhetinate can be mentioned as particularly preferable ones, but not limited thereto.

The object of the present invention is assembling extract and Korean ginseng extract, pepper tincture, hinokitiol, vitamin E and its derivatives, pantothenic acid derivative, nicotinic acid derivative, glycyrrhizic acid and its derivatives, and glycyrrhetinic acid and its derivatives. Hair growth effect,
As a result of examining the range showing the hair loss preventing effect, the amount is preferably 0.001 to 20.0% by weight, more preferably 0.01 to 5.0% by weight, based on the total amount of the hair restoration cosmetic.

The hair nourishing cosmetic composition according to the present invention is manufactured in a usual manner into a dosage form such as a hair tonic, a hair lotion, a hair cream, a hair conditioner, a shampoo, a rinse, a hair gel, a hair mist, a hair foam, etc. It is possible to use.

The hair-growing cosmetic composition of the present invention is applied or sprayed to a topical area (scalp) in accordance with the dosage form for the purpose of hair-growing, hair-growth and / or hair loss prevention.

The hair nourishing cosmetic composition according to the present invention includes a pigment, a fragrance, a bactericide, a preservative, a surfactant, a pigment, a keratolytic agent, an antiandrogen agent and the like within a range that achieves the object of the present invention. They can be appropriately blended.

[0025]

The present invention will be described in detail below with reference to examples and comparative examples, but the present invention is not limited to these examples. The test method used in the present invention is as follows.

Practical Test Method Twice in the morning and evening, 6 consecutive times on the head of 20 male pattern baldness patients
The effect after applying the sample for a month was evaluated. The test results are for hair growth and hair loss prevention.
The number of respondents who answered, "Regrowth of the raw hair or increase of the bristle" and "Reduction of hair loss", respectively, are shown.

Examples 1 to 10 and Comparative Examples 1 to 12 (Heart Tonic) Hair tonics were prepared by mixing active ingredients as shown in Table 2 in the raw material compositions shown in Table 1, and the above test was carried out.

The method of preparing an extract extracted from the fruit of acerola blended in the following Examples and Comparative Examples corresponds to Extraction Example 1 described above, and is specifically shown below.

Preparation Method of Extract from Acerola Fruit (Extraction Method) Acerola fruit (10 kg) was pressed to obtain a pressed juice.
This was concentrated under reduced pressure and filtered to obtain a filtrate (about 2 kg).
A 30 wt% aqueous solution of propylene glycol (18 k
g) was added, and the mixture was allowed to stand in a cool place for 7 days. Thereafter, the mixture was filtered to obtain an extract (about 20 kg).

[0030]

[Table 1]

(1) Preparation Method After dissolving the component (B) shown in Table 1 in the component (A), the component (C) was added, mixed, stirred and dispersed, and filled in a container.

(2) Characteristics

[0033]

[Table 2]

Table 2 shows the results of the tests for each hair tonic. As shown in Table 2, the hair restoration cosmetics according to the present invention of Examples 1 to 10 showed good results in practical tests, and the extracts extracted from the fruits of acerola showed the promotion of the hair growth effect and the hair loss prevention effect. Was. On the other hand, in Comparative Examples 1 to 12, the results of the practical test were not good.

In addition, when the hair-growth cosmetic of any of the examples is used, no inflammation and other symptoms considered to be side effects occur in humans, and the hair-growth cosmetic according to the present invention is also excellent in safety. It was clear.

[0036]

EFFECTS OF THE INVENTION The hair restoration cosmetic according to the present invention has an activity of activating hair matrix cells and is excellent in hair growth effect, hair loss prevention effect and safety.

Claims (1)

[Claims] 1. An extract extracted from the fruit of acerola,
Assembly extract, Korean ginseng extract, red pepper tincture, hinokitiol, vitamin E and its derivatives, pantothenic acid derivatives, nicotinic acid derivatives, glycyrrhizic acid and its derivatives, containing at least one or more substances selected from the group consisting of glycyrrhetinic acid and its derivatives Hair restoration cosmetics characterized by doing.