JP2000516459A5 - - Google Patents

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Publication number
JP2000516459A5
JP2000516459A5 JP1998508844A JP50884498A JP2000516459A5 JP 2000516459 A5 JP2000516459 A5 JP 2000516459A5 JP 1998508844 A JP1998508844 A JP 1998508844A JP 50884498 A JP50884498 A JP 50884498A JP 2000516459 A5 JP2000516459 A5 JP 2000516459A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1998508844A
Other languages
English (en)
Japanese (ja)
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JP2000516459A (ja
JP4475683B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US1997/012203 external-priority patent/WO1998004727A1/en
Publication of JP2000516459A publication Critical patent/JP2000516459A/ja
Publication of JP2000516459A5 publication Critical patent/JP2000516459A5/ja
Application granted granted Critical
Publication of JP4475683B2 publication Critical patent/JP4475683B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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JP50884498A 1996-07-25 1997-07-15 腫瘍関連抗原に対する免疫のための組換えポックス・ウイルス Expired - Lifetime JP4475683B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US68628096A 1996-07-25 1996-07-25
US08/686,280 1996-07-25
PCT/US1997/012203 WO1998004727A1 (en) 1996-07-25 1997-07-15 Recombinant pox virus for immunization against tumor-associated antigens

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009171254A Division JP2009278997A (ja) 1996-07-25 2009-07-22 腫瘍関連抗原に対する免疫のための組換えポックス・ウイルス

Publications (3)

Publication Number Publication Date
JP2000516459A JP2000516459A (ja) 2000-12-12
JP2000516459A5 true JP2000516459A5 (enExample) 2005-03-10
JP4475683B2 JP4475683B2 (ja) 2010-06-09

Family

ID=24755674

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50884498A Expired - Lifetime JP4475683B2 (ja) 1996-07-25 1997-07-15 腫瘍関連抗原に対する免疫のための組換えポックス・ウイルス
JP2009171254A Pending JP2009278997A (ja) 1996-07-25 2009-07-22 腫瘍関連抗原に対する免疫のための組換えポックス・ウイルス

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009171254A Pending JP2009278997A (ja) 1996-07-25 2009-07-22 腫瘍関連抗原に対する免疫のための組換えポックス・ウイルス

Country Status (6)

Country Link
US (1) US7410644B2 (enExample)
EP (2) EP0954593A1 (enExample)
JP (2) JP4475683B2 (enExample)
AU (1) AU731860B2 (enExample)
CA (1) CA2261989C (enExample)
WO (1) WO1998004727A1 (enExample)

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US20010036928A1 (en) * 1996-04-22 2001-11-01 Chamberlain Ronald S. Heterologous boosting immunizations
US6969609B1 (en) 1998-12-09 2005-11-29 The United States Of America As Represented By The Department Of Health And Human Serivces Recombinant vector expressing multiple costimulatory molecules and uses thereof
US7148035B1 (en) 1998-11-18 2006-12-12 Oxford Biomedica (Uk) Limited Polypeptide
CN1298851C (zh) * 1998-11-18 2007-02-07 牛津生物医学(英国)有限公司 多肽
JP4409097B2 (ja) * 1998-12-09 2010-02-03 アメリカ合衆国 複数の共刺激分子を発現する組換えベクターおよびその利用
EP1865065A1 (en) * 1998-12-09 2007-12-12 The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services A recombinant vector expressing multiple costimulatory molecules and uses thereof
PT1496939E (pt) * 2002-04-09 2007-11-22 Sanofi Pasteur Ltd ''ácido nucleico de cea modificado e vectores de expressão''
CA2536317A1 (en) * 2003-08-21 2005-03-03 Virax Development Pty Ltd Poxvirus vector encoding prostate specific antigens for treatment of prostate cancer
DE602004032365D1 (de) * 2003-10-08 2011-06-01 Sanofi Pasteur Inc Modifizierter cea/b7-vektor
EP1687322B1 (en) 2003-11-12 2017-02-08 The Government of the United States of America, represented by the Secretary, Department of Health and Human Services Custom vectors for treating and preventing pancreatic cancer
JP4995575B2 (ja) * 2003-11-12 2012-08-08 アメリカ合衆国 乳癌を処置および予防するためのシステム
US20110287089A1 (en) 2009-01-13 2011-11-24 Karola Rittner Use of a saccharomyces cerevisiae mitochondrial nucleic acids fraction for immune stimulation
PT2382474E (pt) 2009-01-20 2015-06-03 Transgene Sa Icam-1 solúvel como biomarcador para a previsão de uma resposta terapêutica
AU2010227611B2 (en) 2009-03-24 2014-05-29 Transgene Sa Biomarker for monitoring patients
AU2010237215B2 (en) 2009-04-17 2014-05-01 Transgene Sa Biomarker for monitoring patients
US9261512B2 (en) 2009-07-10 2016-02-16 Transgene, S.A. Biomarker for treating cancer patients
US9804163B2 (en) 2010-08-06 2017-10-31 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Biomarkers for prostate cancer and methods for their detection
US9725494B2 (en) * 2013-05-17 2017-08-08 United States Of America, As Represented By The Secretary, Department Of Health And Human Services Soluble CD27 (sCD27) and the use thereof
EP3065770B1 (en) * 2013-11-05 2020-10-28 Bavarian Nordic A/S Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and an antagonist of an immune checkpoint inhibitor
EP3142689B1 (en) 2014-05-13 2020-11-11 Bavarian Nordic A/S Combination therapy for treating cancer with a poxvirus expressing a tumor antigen and a monoclonal antibody against tim-3
AU2015289081B2 (en) 2014-07-16 2020-02-06 Transgene Sa Combination of oncolytic virus with immune checkpoint modulators
CN107949397A (zh) 2015-02-13 2018-04-20 特兰斯吉恩股份有限公司 免疫治疗疫苗和抗体组合治疗
IL256869B (en) 2015-07-31 2022-07-01 Bavarian Nordic As promoters for increased expression in poxviruses
EP3400009A2 (en) 2016-01-05 2018-11-14 The U.S.A. As Represented By The Secretary, Department Of Health And Human Services Combination of histone deacetylase inhibitor and immunotherapy
ES2924741T3 (es) 2016-01-28 2022-10-10 Inst Nat Sante Rech Med Métodos para incrementar la potencia de los inhibidores del punto de control inmunitario
WO2017136342A1 (en) 2016-02-02 2017-08-10 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Fulvestrant for inducing immune-mediated cytotoxic lysis of cancer cells
CA3023022A1 (en) 2016-05-04 2017-11-09 Transgene Sa Combination therapy with cpg tlr9 ligand
WO2018060368A2 (en) 2016-09-28 2018-04-05 Bavarian Nordic A/S Compositions and methods for enhancing the stability of transgenes in poxviruses
US20190328869A1 (en) 2016-10-10 2019-10-31 Transgene Sa Immunotherapeutic product and mdsc modulator combination therapy
WO2018091680A1 (en) 2016-11-18 2018-05-24 Transgene Sa Cowpox-based oncolytic vectors
AU2017387549B2 (en) 2016-12-28 2023-07-06 Transgene Sa Oncolytic viruses and therapeutic molecules
CA3058966A1 (en) 2017-04-14 2018-10-18 Tollnine, Inc. Immunomodulating polynucleotides, antibody conjugates thereof, and methods of their use
JP2020519666A (ja) 2017-05-15 2020-07-02 ヤンセン ファッシンズ アンド プリベンション ベーフェーJanssen Vaccines & Prevention B.V. 安定性のウイルス含有組成物
EP3624845A1 (en) 2017-05-15 2020-03-25 Janssen Vaccines & Prevention B.V. Stable virus-containing composition
WO2019020543A1 (en) 2017-07-28 2019-01-31 Transgene Sa ONCOLYTIC VIRUSES EXPRESSING AGENTS TARGETING METABOLIC IMMUNE MODULATORS
MX2020001856A (es) 2017-08-24 2020-07-13 Bavarian Nordic As Terapia de combinacion para tratar el cancer con administracion intravenosa de un virus vaccinia ankara modificado (mva) recombinante y un anticuerpo.
MX2020009262A (es) 2018-03-07 2021-01-08 Transgene Vectores de parapoxvirus.
WO2020011754A1 (en) 2018-07-09 2020-01-16 Transgene Chimeric vaccinia viruses
EP3847246A1 (en) 2018-09-06 2021-07-14 Bavarian Nordic A/S Storage improved poxvirus compositions
US20220233607A1 (en) 2019-05-29 2022-07-28 Université De Tours Toxoplasma platform for treating cancer
AU2021226023A1 (en) 2020-02-28 2022-09-15 Tallac Therapeutics, Inc. Transglutaminase-mediated conjugation
MX2022011071A (es) 2020-03-12 2022-09-23 Bavarian Nordic As Composiciones que mejoran la estabilidad del poxvirus.
WO2024038175A1 (en) 2022-08-18 2024-02-22 Transgene Chimeric poxviruses

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US5093258A (en) 1988-08-26 1992-03-03 Therion Biologics Corporation Recombinant fowlpox virus and recombination vector
WO1991019803A1 (en) 1990-06-19 1991-12-26 Applied Biotechnology, Incorporated Self assembled, defective, nonself-propagating viral particles
DK0584266T3 (da) * 1991-05-06 2003-12-29 Us Gov Health & Human Serv Rekombinant virus udtrykkende carcinoembryonalt antigen og fremgangsmåder til anvendelse heraf
US5445953A (en) 1991-08-26 1995-08-29 Immuno Aktiengesellschaft Direct molecular cloning of a modified poxvirus genome
US5382425A (en) 1992-01-13 1995-01-17 Syntro Corporation Recombinant swinepox virus
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DE69519521T2 (de) * 1994-10-03 2001-06-28 The Government Of The United States Of America, As Represented By The Secretary National Institute Of Health Zusammensetzung enthaltend ein antigen exprimierendes rekombinantes virus und ein immunstimulierendes molekül exprimierendes rekombinantes virus
US6001349A (en) * 1995-02-22 1999-12-14 Therion Biologics Corporation Generation of human cytotoxic T-cells specific for carcinoma self-associated antigens and uses thereof
US6165460A (en) * 1995-07-10 2000-12-26 Therion Biologics Corporation Generation of immune responses to prostate-specific antigen (PSA)

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