|
US5869270A
(en)
|
1996-01-31 |
1999-02-09 |
Sunol Molecular Corporation |
Single chain MHC complexes and uses thereof
|
|
CA2250166A1
(en)
*
|
1996-03-28 |
1997-10-02 |
The Johns Hopkins University |
Soluble divalent and multivalent heterodimeric analogs of proteins
|
|
US6458354B1
(en)
|
1996-03-28 |
2002-10-01 |
The Johns Hopkins University |
Molecular complexes which modify immune responses
|
|
US6211342B1
(en)
*
|
1996-07-18 |
2001-04-03 |
Children's Hospital Medical Center |
Multivalent MHC complex peptide fusion protein complex for stimulating specific T cell function
|
|
US6268411B1
(en)
*
|
1997-09-11 |
2001-07-31 |
The Johns Hopkins University |
Use of multivalent chimeric peptide-loaded, MHC/ig molecules to detect, activate or suppress antigen-specific T cell-dependent immune responses
|
|
ATE423789T1
(de)
*
|
1997-09-16 |
2009-03-15 |
Univ Oregon Health & Science |
Rekombinante mhc-moleküle welche nützlich sind für die manipulation von antigen-spezifischen t- zellen
|
|
US20030007978A1
(en)
*
|
1997-09-16 |
2003-01-09 |
Burrows Gregory G. |
Recombinant MHC molecules useful for manipulation of antigen-specific T-cells
|
|
US6232445B1
(en)
*
|
1997-10-29 |
2001-05-15 |
Sunol Molecular Corporation |
Soluble MHC complexes and methods of use thereof
|
|
GB2339782A
(en)
*
|
1998-06-05 |
2000-02-09 |
Philip Michael Savage |
Chimeric protein complexes comprising HLA class I antigens
|
|
CN1348332A
(zh)
*
|
1999-03-03 |
2002-05-08 |
宾夕法尼亚大学理事会 |
疫苗和基因治疗组合物以及其制备和使用方法
|
|
HK1041312B
(en)
*
|
1999-04-16 |
2006-09-29 |
Ortho-Mcneil Pharmaceutical, Inc. |
Method for the detection of antigen specific t-cells
|
|
KR100873157B1
(ko)
*
|
1999-05-06 |
2008-12-10 |
웨이크 포리스트 유니버시티 |
면역 반응을 유발하는 항원을 동정하기 위한 조성물과 방법
|
|
FR2796953B1
(fr)
*
|
1999-07-29 |
2003-10-10 |
Centre Nat Rech Scient |
Proteines recombinantes, et complexes moleculaires derives de ces proteines, analogues a des molecules impliquees dans les reponses immunitaires
|
|
US6995237B1
(en)
*
|
1999-10-27 |
2006-02-07 |
Cel-Sci Corporation |
Preparation and composition of peptides useful for treatment of autoimmune and transplant related graft versus host conditions
|
|
US6316256B1
(en)
*
|
2000-01-03 |
2001-11-13 |
Tr Associates, L.L.C. |
Method for protein transfer
|
|
US7541184B2
(en)
*
|
2000-02-24 |
2009-06-02 |
Invitrogen Corporation |
Activation and expansion of cells
|
|
US7572631B2
(en)
|
2000-02-24 |
2009-08-11 |
Invitrogen Corporation |
Activation and expansion of T cells
|
|
US20040191260A1
(en)
|
2003-03-26 |
2004-09-30 |
Technion Research & Development Foundation Ltd. |
Compositions capable of specifically binding particular human antigen presenting molecule/pathogen-derived antigen complexes and uses thereof
|
|
JP2004503213A
(ja)
*
|
2000-03-27 |
2004-02-05 |
テクニオン リサーチ アンド ディベロップメント ファウンデーション リミテッド |
１本鎖クラスｉ主要組織適合性複合体、それをコードする構築物およびそれを生成する方法
|
|
AU2001253812A1
(en)
*
|
2000-04-28 |
2001-11-12 |
Genzyme Corporation |
In vivo loading of mhc
|
|
JP2004501364A
(ja)
*
|
2000-05-25 |
2004-01-15 |
スノル・モレキュラー・コーポレーション |
Ｔ−細胞レセプター相互作用のモジュレーション
|
|
GB0110547D0
(en)
*
|
2001-04-30 |
2001-06-20 |
Avidex Ltd |
Method
|
|
US6811785B2
(en)
*
|
2001-05-07 |
2004-11-02 |
Mount Sinai School Of Medicine Of New York University |
Multivalent MHC class II—peptide chimeras
|
|
CA2487779C
(en)
|
2001-06-05 |
2012-10-02 |
Altor Bioscience Corporation |
P53 binding t cell receptor molecules and uses thereof
|
|
US8022190B2
(en)
*
|
2001-06-19 |
2011-09-20 |
Technion Research & Development Foundation Ltd. |
Immuno-molecules containing viral proteins, compositions thereof and methods of using
|
|
US20030017134A1
(en)
*
|
2001-06-19 |
2003-01-23 |
Technion Research And Development Foundation Ltd. |
Methods and pharmaceutical compositions for immune deception, particularly useful in the treatment of cancer
|
|
US20040265272A1
(en)
*
|
2001-09-28 |
2004-12-30 |
Aikichi Iwamoto |
Mammalian cell-infecting virus vector encoding epitope-bound beta2m and utilization thereof
|
|
JP2005527490A
(ja)
*
|
2002-01-18 |
2005-09-15 |
イノヴィオ アーエス |
筋肉内投与のための二重特異性抗体ｄｎａ構築物
|
|
US20030199024A1
(en)
*
|
2002-04-19 |
2003-10-23 |
Hansen Ted H. |
Single chain trimers of class I MHC molecules
|
|
US20050084967A1
(en)
*
|
2002-06-28 |
2005-04-21 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
JP2006506987A
(ja)
*
|
2002-06-28 |
2006-03-02 |
エクサイト セラピーズ インコーポレーティッド |
自己免疫および臓器または造血幹細胞移植に関連する免疫学的欠損を有する患者における免疫レパートリー回復のための組成物および方法
|
|
US20040175373A1
(en)
*
|
2002-06-28 |
2004-09-09 |
Xcyte Therapies, Inc. |
Compositions and methods for eliminating undesired subpopulations of T cells in patients with immunological defects related to autoimmunity and organ or hematopoietic stem cell transplantation
|
|
WO2004006951A1
(en)
*
|
2002-07-12 |
2004-01-22 |
The Johns Hopkins University |
Reagents and methods for engaging unique clonotypic lymphocyte receptors
|
|
CA2492200A1
(en)
*
|
2002-07-12 |
2004-01-22 |
Dana-Farber Cancer Institute, Inc. |
Novel compositions and methods for the generation of mhc class ii compounds by peptide exchange
|
|
EP1559780A1
(en)
*
|
2002-10-01 |
2005-08-03 |
Dnavec Research Inc. |
Method of strengthening foreign epitope presentation by mhc class i by inhibiting tap activity
|
|
CA2957200C
(en)
*
|
2002-10-16 |
2020-05-26 |
Gen-Probe Incorporated |
Compositions and methods for detecting west nile virus
|
|
US7927840B2
(en)
*
|
2006-09-11 |
2011-04-19 |
Gen Probe Incorporated |
Method for detecting West Nile Virus nucleic acids in the 3′ non-coding region
|
|
DK1625148T3
(da)
|
2003-05-21 |
2013-01-14 |
Biotech Tools Sa |
Peptidkompleks
|
|
EP2316844A3
(en)
*
|
2003-05-21 |
2011-07-20 |
Biotech Tools S.A. |
Peptide complex
|
|
WO2005044982A2
(en)
|
2003-09-05 |
2005-05-19 |
Oregon Health & Science University |
Monomeric recombinant mhc molecules useful for manipulation of antigen-specific t cells
|
|
KR101131297B1
(ko)
|
2003-11-10 |
2012-03-30 |
알토 바이오사이언스 코포레이션 |
가용성 티씨알 분자 및 이용 방법
|
|
US20050227351A1
(en)
*
|
2004-04-08 |
2005-10-13 |
Awdalla Essam T |
Methods and compound protein molecules used for inducing cytotoxic cell-mediated immune response in a mammal against a pathogenic cell
|
|
DE102004019803A1
(de)
*
|
2004-04-23 |
2005-11-10 |
Imusyn Gmbh & Co.Kg |
Verfahren zur Herstellung löslicher MHC-Proteine
|
|
GB2422834B8
(en)
*
|
2005-02-04 |
2007-01-04 |
Proimmune Ltd |
MHC oligomer and method of making the same
|
|
US20090061478A1
(en)
*
|
2006-01-30 |
2009-03-05 |
Lene Have Poulsen |
High-Speed Quantification of Antigen Specific T-Cells in Whole Blood by Flow Cytometry
|
|
US8518697B2
(en)
*
|
2006-04-04 |
2013-08-27 |
Washington University |
Single chain trimers and uses therefor
|
|
EA200870555A1
(ru)
*
|
2006-05-19 |
2009-04-28 |
Тева Фармасьютикал Индастриз, Лтд. |
Слитые белки, их применение и способы их получения
|
|
EP2361930A3
(en)
|
2007-03-26 |
2011-10-26 |
Dako Denmark A/S |
Multimers of MHC-peptide complexes and uses thereof in Borrelia infectious diseases
|
|
EP3620465B1
(en)
*
|
2007-07-03 |
2025-02-19 |
Dako Denmark A/S |
Improved methods for generation, labeling and use of mhc multimers
|
|
EP2197908A2
(en)
|
2007-09-27 |
2010-06-23 |
Dako Denmark A/S |
Mhc multimers in tuberculosis diagnostics, vaccine and therapeutics
|
|
US10968269B1
(en)
|
2008-02-28 |
2021-04-06 |
Agilent Technologies, Inc. |
MHC multimers in borrelia diagnostics and disease
|
|
US10722562B2
(en)
*
|
2008-07-23 |
2020-07-28 |
Immudex Aps |
Combinatorial analysis and repair
|
|
GB0817244D0
(en)
*
|
2008-09-20 |
2008-10-29 |
Univ Cardiff |
Use of a protein kinase inhibitor to detect immune cells, such as T cells
|
|
US11992518B2
(en)
|
2008-10-02 |
2024-05-28 |
Agilent Technologies, Inc. |
Molecular vaccines for infectious disease
|
|
US10369204B2
(en)
|
2008-10-02 |
2019-08-06 |
Dako Denmark A/S |
Molecular vaccines for infectious disease
|
|
US20110124019A1
(en)
*
|
2009-11-25 |
2011-05-26 |
The Charlotte-Mecklenburg Hospital Authority |
Method of using carbonic anhydrase to detect hemolysis
|
|
JP5665021B2
(ja)
*
|
2010-03-08 |
2015-02-04 |
国立大学法人東京農工大学 |
融合ｍｈｃ分子連結磁気微粒子、抗原ペプチドのスクリーニング方法、組換えベクター、及び磁性細菌の形質転換体
|
|
WO2011147894A1
(en)
|
2010-05-25 |
2011-12-01 |
Forschungsverbund Berlin E.V. |
Chimeric mhc class ii proteinpeptide
|
|
GB201013767D0
(en)
*
|
2010-08-17 |
2010-09-29 |
Isis Innovation |
Identification of ligands and their use
|
|
EP2699593B2
(en)
|
2011-04-20 |
2020-11-04 |
University of Washington Through Its Center for Commercialization |
Beta-2 microglobulin-deficient cells
|
|
US8753309B2
(en)
|
2011-06-24 |
2014-06-17 |
The Invention Science Fund I, Llc |
Device, system, and method including micro-patterned cell treatment array
|
|
CN106940268B
(zh)
|
2012-02-23 |
2021-09-21 |
朱诺治疗有限公司 |
细胞和其它复杂生物材料的色谱分离
|
|
US10274499B2
(en)
|
2012-03-27 |
2019-04-30 |
The University Of Western Ontario |
SH2 domain variants
|
|
CA3085032A1
(en)
*
|
2012-04-17 |
2013-10-24 |
University Of Washington Through Its Center For Commercialization |
Hla class ii deficient cells, hla class i deficient cells capable of expressing hla class ii proteins, and uses thereof
|
|
AU2013259598B2
(en)
*
|
2012-05-08 |
2018-10-04 |
Western University Of Health Sciences |
Standardized ex vivo platforms for the antigen-specific expansion of CD4+ T cell populations
|
|
EP3640375A3
(en)
|
2012-12-11 |
2020-07-29 |
Albert Einstein College of Medicine |
Methods for high throughput receptor/ligand identification
|
|
US9975944B2
(en)
|
2013-03-12 |
2018-05-22 |
Tel Hashomer Medical Research Infrastructure And Services Ltd. |
Synthetic peptides for the treatment of autoimmune diseases
|
|
GB201313352D0
(en)
|
2013-07-26 |
2013-09-11 |
Isis Innovation |
Identification of peptide ligands
|
|
AU2015277460B2
(en)
*
|
2014-06-18 |
2020-10-08 |
Albert Einstein College Of Medicine, Inc. |
Syntac polypeptides and uses thereof
|
|
KR20170083534A
(ko)
|
2014-09-19 |
2017-07-18 |
리제너론 파마슈티칼스 인코포레이티드 |
키메라 항원 수용체
|
|
MA45489A
(fr)
|
2015-10-22 |
2018-08-29 |
Juno Therapeutics Gmbh |
Procédés de culture de cellules, kits et appareil associés
|
|
RU2761555C2
(ru)
|
2015-10-22 |
2021-12-09 |
Джуно Терапьютикс Гмбх |
Способы, наборы, средства и устройства для трансдукции
|
|
AU2017266905B2
(en)
|
2016-05-18 |
2022-12-15 |
Albert Einstein College Of Medicine, Inc. |
Variant PD-L1 polypeptides, T-cell modulatory multimeric polypeptides, and methods of use thereof
|
|
KR20190019068A
(ko)
|
2016-05-18 |
2019-02-26 |
큐 바이오파마, 인크. |
T-세포 조절 다량체 폴리펩타이드 및 이의 사용 방법
|
|
US11583575B2
(en)
|
2016-09-06 |
2023-02-21 |
Roche Sequencing Solutions, Inc. |
MHC-bound peptide arrays and methods of use thereof
|
|
WO2018170168A1
(en)
|
2017-03-15 |
2018-09-20 |
Cue Biopharma, Inc. |
Methods for modulating an immune response
|
|
JP7339160B2
(ja)
|
2017-04-27 |
2023-09-05 |
ジュノ セラピューティクス ゲーエムベーハー |
オリゴマー粒子試薬およびその使用方法
|
|
WO2019139896A1
(en)
|
2018-01-09 |
2019-07-18 |
Cue Biopharma, Inc. |
Multimeric t-cell modulatory polypeptides and methods of use thereof
|
|
AU2019370705B2
(en)
|
2018-10-31 |
2026-01-22 |
Juno Therapeutics Gmbh |
Methods for selection and stimulation of cells and apparatus for same
|
|
US12258373B2
(en)
|
2018-12-17 |
2025-03-25 |
Immudex Aps |
Panel comprising Borrelia MHC multimers
|
|
WO2020142750A2
(en)
*
|
2019-01-03 |
2020-07-09 |
Regents Of The University Of Minnesota |
Genetically modified cells, tissues, and organs for treating disease
|
|
TWI852977B
(zh)
|
2019-01-10 |
2024-08-21 |
美商健生生物科技公司 |
前列腺新抗原及其用途
|
|
TW202144389A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在多發性骨髓瘤中表現之新抗原及其用途
|
|
TW202144388A
(zh)
|
2020-02-14 |
2021-12-01 |
美商健生生物科技公司 |
在卵巢癌中表現之新抗原及其用途
|
|
CN116096405A
(zh)
|
2020-05-12 |
2023-05-09 |
Cue生物制药股份有限公司 |
多聚体t细胞调节多肽及其使用方法
|
|
EP4175664A2
(en)
|
2020-07-06 |
2023-05-10 |
Janssen Biotech, Inc. |
Prostate neoantigens and their uses
|
|
WO2022056014A1
(en)
|
2020-09-09 |
2022-03-17 |
Cue Biopharma, Inc. |
Mhc class ii t-cell modulatory multimeric polypeptides for treating type 1 diabetes mellitus (t1d) and methods of use thereof
|
|
US11926667B2
(en)
|
2020-10-13 |
2024-03-12 |
Janssen Biotech, Inc. |
Bioengineered T cell mediated immunity, materials and other methods for modulating cluster of differentiation IV and/or VIII
|