JP2000513805A5 - - Google Patents
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- Publication number
- JP2000513805A5 JP2000513805A5 JP1997529635A JP52963597A JP2000513805A5 JP 2000513805 A5 JP2000513805 A5 JP 2000513805A5 JP 1997529635 A JP1997529635 A JP 1997529635A JP 52963597 A JP52963597 A JP 52963597A JP 2000513805 A5 JP2000513805 A5 JP 2000513805A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Description
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9609521.1A GB9609521D0 (en) | 1996-05-08 | 1996-05-08 | Substances and their therapeutic use |
GB9609521.1 | 1996-05-08 | ||
GBGB9621314.5A GB9621314D0 (en) | 1996-10-09 | 1996-10-09 | Substances and their therapeutic use |
GB9621314.5 | 1996-10-09 | ||
PCT/GB1997/001250 WO1997042222A1 (en) | 1996-05-08 | 1997-05-08 | Methods and means for inhibition of cdk4 activity |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2000513805A JP2000513805A (ja) | 2000-10-17 |
JP2000513805A5 true JP2000513805A5 (ja) | 2005-01-13 |
JP4205165B2 JP4205165B2 (ja) | 2009-01-07 |
Family
ID=26309279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52963597A Expired - Fee Related JP4205165B2 (ja) | 1996-05-08 | 1997-05-08 | Cdk4活性の阻害のための方法と手段 |
Country Status (7)
Country | Link |
---|---|
US (3) | US6962792B1 (ja) |
EP (1) | EP0898580B9 (ja) |
JP (1) | JP4205165B2 (ja) |
AT (1) | ATE333465T1 (ja) |
AU (1) | AU2707797A (ja) |
DE (2) | DE69736351T4 (ja) |
WO (1) | WO1997042222A1 (ja) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0898580B9 (en) | 1996-05-08 | 2009-08-12 | Cyclacel Limited | Methods and means for inhibition of cdk4 activity |
GB9727277D0 (en) * | 1997-12-23 | 1998-02-25 | Medical Res Council | Assay |
DE69907152D1 (de) * | 1998-02-18 | 2003-05-28 | Theryte Ltd | Krebsbehandlung |
AU3103599A (en) * | 1998-03-23 | 1999-10-18 | E.I. Du Pont De Nemours And Company | Plant cell cyclin genes |
EP1338652A3 (en) * | 1998-03-23 | 2004-05-19 | E.I.Du pont de nemours and company | Plant cell cyclin genes |
CA2367385A1 (en) * | 1999-04-07 | 2000-10-12 | E.I. Du Pont De Nemours And Company | Cell cycle in plants |
US20050153894A1 (en) * | 1999-11-30 | 2005-07-14 | Cyclacel Limited | p21 peptides |
US7449544B2 (en) | 1999-11-30 | 2008-11-11 | Cyclacel Limited | p21 peptides |
GB2369823B (en) * | 1999-11-30 | 2003-06-04 | Cyclacel Ltd | Assays for cyclin-interacting compounds |
GB9928323D0 (en) * | 1999-11-30 | 2000-01-26 | Cyclacel Ltd | Peptides |
GB0012528D0 (en) * | 2000-05-23 | 2000-07-12 | Univ Palackeho | Triterpenoid derivatives |
GB0030378D0 (en) | 2000-12-13 | 2001-01-24 | Cyclacel Ltd | Compound |
JP2005534334A (ja) * | 2002-08-07 | 2005-11-17 | エクセリクシス, インク. | p21経路のモディファイヤーとしてのCSNK1GSおよび使用方法 |
GB0229151D0 (en) | 2002-12-13 | 2003-01-15 | St Georges Entpr Ltd | Product and method |
EP1687331A1 (en) * | 2003-10-20 | 2006-08-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Tyrosine phosphorylation of cdk inhibitor proteins of the cip/kip family |
CA2542880A1 (en) * | 2003-10-21 | 2005-05-12 | Cyclacel Limited | Pyrimidin-4-yl-3, 4-thione compounds and their use in therapy |
GB0402653D0 (en) * | 2004-02-06 | 2004-03-10 | Cyclacel Ltd | Compounds |
GB0411791D0 (en) * | 2004-05-26 | 2004-06-30 | Cyclacel Ltd | Compounds |
PL1799230T3 (pl) | 2004-08-27 | 2013-05-31 | Cyclacel Ltd | Purynowe i pirymidynowe inhibitory CDK i ich zastosowanie do leczenia chorób autoimmunologicznych |
US20090286738A1 (en) * | 2005-06-29 | 2009-11-19 | St. George's Enterprises Limited | Gene Regulation |
US9539327B2 (en) * | 2007-11-26 | 2017-01-10 | The Research Foundation For The State University Of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
US9040046B2 (en) | 2011-01-31 | 2015-05-26 | Kai Xu | Sodium pump antibody agonists and methods of treating heart disease using the same |
WO2020055758A1 (en) | 2018-09-10 | 2020-03-19 | Mirati Therapeutics, Inc. | Combination therapies |
CN118324906A (zh) * | 2024-06-14 | 2024-07-12 | 上海交通大学医学院附属上海儿童医学中心 | p21特异性修饰的抗体及制备方法和应用 |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2759164A1 (de) | 1977-12-31 | 1979-07-12 | Basf Ag | Photopolymerisierbare ueberzugs- und aufzeichnungsmaterialien, enthaltend einen photoinitiator und eine organische halogenverbindung |
US5229018A (en) | 1986-02-24 | 1993-07-20 | Forrest Gabriel T | Completion and workover fluid for oil and gas wells comprising ground peanut hulls |
FR2662698A1 (fr) | 1990-06-05 | 1991-12-06 | Centre Nat Rech Scient | Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite. |
US5302706A (en) | 1991-12-16 | 1994-04-12 | Baylor College Of Medicine | Senescent cell derived inhibitors of DNA synthesis |
US5596079A (en) | 1991-12-16 | 1997-01-21 | Smith; James R. | Mimetics of senescent cell derived inhibitors of DNA synthesis |
JP3485186B2 (ja) | 1992-10-16 | 2004-01-13 | コールド・スプリング・ハーバー・ラボラトリー | サイクリン複合体の転位およびそれに関連する使用 |
GB9305448D0 (en) | 1993-03-17 | 1993-05-05 | British Tech Group | Semiconductor structure and method of manufacturing same |
JP3822232B2 (ja) | 1993-08-30 | 2006-09-13 | ベイラー・カレッジ・オブ・メディシン | 老化細胞由来dna合成阻害因子 |
WO1995013375A1 (en) | 1993-11-10 | 1995-05-18 | The Johns Hopkins University | Tumor suppressor waf1 |
WO1995031995A1 (en) | 1994-05-24 | 1995-11-30 | Baylor College Of Medicine | Mimetics of senescent cell derived inhibitors of dna synthesis |
GB9422175D0 (en) | 1994-11-03 | 1994-12-21 | Univ Dundee | Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof |
GB9509557D0 (en) | 1995-05-11 | 1995-07-05 | Univ Dundee | PCNA binding substance |
WO1997003681A1 (en) | 1995-07-20 | 1997-02-06 | Worcester Foundation For Biomedical Research, Inc. | Methods for selectively killing or inhibiting the growth of cells expressing the waf1 gene |
US5672508A (en) | 1996-01-23 | 1997-09-30 | Mitotix, Inc. | Inhibitors of cell-cycle progression, and uses related thereto |
EP0898580B9 (en) | 1996-05-08 | 2009-08-12 | Cyclacel Limited | Methods and means for inhibition of cdk4 activity |
-
1997
- 1997-05-08 EP EP97920857A patent/EP0898580B9/en not_active Expired - Lifetime
- 1997-05-08 DE DE69736351T patent/DE69736351T4/de not_active Expired - Lifetime
- 1997-05-08 DE DE69736351A patent/DE69736351D1/de not_active Expired - Fee Related
- 1997-05-08 US US09/180,269 patent/US6962792B1/en not_active Expired - Fee Related
- 1997-05-08 JP JP52963597A patent/JP4205165B2/ja not_active Expired - Fee Related
- 1997-05-08 WO PCT/GB1997/001250 patent/WO1997042222A1/en active IP Right Grant
- 1997-05-08 AT AT97920857T patent/ATE333465T1/de not_active IP Right Cessation
- 1997-05-08 AU AU27077/97A patent/AU2707797A/en not_active Abandoned
-
2003
- 2003-08-22 US US10/646,267 patent/US20040214765A1/en not_active Abandoned
-
2008
- 2008-06-04 US US12/133,242 patent/US20080249025A1/en not_active Abandoned