JP2000513805A5 - - Google Patents
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- Publication number
- JP2000513805A5 JP2000513805A5 JP1997529635A JP52963597A JP2000513805A5 JP 2000513805 A5 JP2000513805 A5 JP 2000513805A5 JP 1997529635 A JP1997529635 A JP 1997529635A JP 52963597 A JP52963597 A JP 52963597A JP 2000513805 A5 JP2000513805 A5 JP 2000513805A5
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9609521.1A GB9609521D0 (en) | 1996-05-08 | 1996-05-08 | Substances and their therapeutic use |
| GB9609521.1 | 1996-10-09 | ||
| GB9621314.5 | 1996-10-09 | ||
| GBGB9621314.5A GB9621314D0 (en) | 1996-10-09 | 1996-10-09 | Substances and their therapeutic use |
| PCT/GB1997/001250 WO1997042222A1 (en) | 1996-05-08 | 1997-05-08 | Methods and means for inhibition of cdk4 activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2000513805A JP2000513805A (ja) | 2000-10-17 |
| JP2000513805A5 true JP2000513805A5 (Direct) | 2005-01-13 |
| JP4205165B2 JP4205165B2 (ja) | 2009-01-07 |
Family
ID=26309279
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP52963597A Expired - Fee Related JP4205165B2 (ja) | 1996-05-08 | 1997-05-08 | Ｃｄｋ４活性の阻害のための方法と手段 |
Country Status (7)
| Country | Link |
|---|---|
| US (3) | US6962792B1 (Direct) |
| EP (1) | EP0898580B9 (Direct) |
| JP (1) | JP4205165B2 (Direct) |
| AT (1) | ATE333465T1 (Direct) |
| AU (1) | AU2707797A (Direct) |
| DE (2) | DE69736351T4 (Direct) |
| WO (1) | WO1997042222A1 (Direct) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997042222A1 (en) | 1996-05-08 | 1997-11-13 | Cyclacel Limited | Methods and means for inhibition of cdk4 activity |
| GB9727277D0 (en) * | 1997-12-23 | 1998-02-25 | Medical Res Council | Assay |
| DE69907151D1 (de) * | 1998-02-18 | 2003-05-28 | Theryte Ltd | Krebsbehandlung |
| BR9907965A (pt) * | 1998-03-23 | 2000-12-12 | Du Pont | Fragmento de ácido nucléico isolado, gene quimérico, célula hospedeira transformada, polipetìdios, processo de alteração do nìvel de expressão de uma proteìna ciclina em uma célula hospedeira, método de obtenção de um fragmento de ácido nucleìco, produto e método de avaliação de pelo menos um composto quanto à sua capacidade de inibir a atividade de uma proteìna ciclina |
| EP1338652A3 (en) * | 1998-03-23 | 2004-05-19 | E.I.Du pont de nemours and company | Plant cell cyclin genes |
| WO2000038733A1 (en) * | 1998-12-24 | 2000-07-06 | Ucb S.A. | Peptidic product, process and composition |
| CA2367385A1 (en) * | 1999-04-07 | 2000-10-12 | E.I. Du Pont De Nemours And Company | Cell cycle in plants |
| GB9928323D0 (en) * | 1999-11-30 | 2000-01-26 | Cyclacel Ltd | Peptides |
| GB2369823B (en) * | 1999-11-30 | 2003-06-04 | Cyclacel Ltd | Assays for cyclin-interacting compounds |
| US7449544B2 (en) | 1999-11-30 | 2008-11-11 | Cyclacel Limited | p21 peptides |
| US20050153894A1 (en) * | 1999-11-30 | 2005-07-14 | Cyclacel Limited | p21 peptides |
| GB0012528D0 (en) * | 2000-05-23 | 2000-07-12 | Univ Palackeho | Triterpenoid derivatives |
| GB0030378D0 (en) | 2000-12-13 | 2001-01-24 | Cyclacel Ltd | Compound |
| WO2004015073A2 (en) * | 2002-08-07 | 2004-02-19 | Exelixis, Inc. | MP21S AS MODIFIERS OF THE p21 PATHWAY AND METHODS OF USE |
| GB0229151D0 (en) | 2002-12-13 | 2003-01-15 | St Georges Entpr Ltd | Product and method |
| WO2005040207A1 (en) * | 2003-10-20 | 2005-05-06 | F. Hoffmann-La Roche Ag | Tyrosine phosphorylation of cdk inhibitor proteins of the cip/kip family |
| AU2004285745A1 (en) * | 2003-10-21 | 2005-05-12 | Cyclacel Limited | Pyrimidin-4-YL-3, 4-thione compounds and their use in therapy |
| GB0402653D0 (en) * | 2004-02-06 | 2004-03-10 | Cyclacel Ltd | Compounds |
| GB0411791D0 (en) * | 2004-05-26 | 2004-06-30 | Cyclacel Ltd | Compounds |
| ES2403558T3 (es) | 2004-08-27 | 2013-05-20 | Cyclacel Limited | Inhibidores purínicos y pirimidínicos de CDK y su uso para el tratamiento de enfermedades autoinmunitarias |
| JP2009500314A (ja) * | 2005-06-29 | 2009-01-08 | セント ジョージス エンタープライシス リミテッド | 遺伝子調節 |
| WO2009070650A1 (en) * | 2007-11-26 | 2009-06-04 | The Research Foundation Of State University Of New York | Small molecule cancer treatments that cause necrosis in cancer cells but do not affect normal cells |
| US9040046B2 (en) | 2011-01-31 | 2015-05-26 | Kai Xu | Sodium pump antibody agonists and methods of treating heart disease using the same |
| AU2019247554A1 (en) | 2018-04-06 | 2020-11-26 | Oncolyze, Inc. | Compositions for use in lysis of selective cancer cells |
| SI3849537T1 (sl) | 2018-09-10 | 2025-03-31 | Mirati Therapeutics, Inc. | Kombinirane terapije |
| CN118324906A (zh) * | 2024-06-14 | 2024-07-12 | 上海交通大学医学院附属上海儿童医学中心 | p21特异性修饰的抗体及制备方法和应用 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2759164A1 (de) | 1977-12-31 | 1979-07-12 | Basf Ag | Photopolymerisierbare ueberzugs- und aufzeichnungsmaterialien, enthaltend einen photoinitiator und eine organische halogenverbindung |
| US5229018A (en) | 1986-02-24 | 1993-07-20 | Forrest Gabriel T | Completion and workover fluid for oil and gas wells comprising ground peanut hulls |
| FR2662698A1 (fr) * | 1990-06-05 | 1991-12-06 | Centre Nat Rech Scient | Nouveaux facteurs de croissance neurotropes comprenant un peptide homeoboite. |
| US5596079A (en) | 1991-12-16 | 1997-01-21 | Smith; James R. | Mimetics of senescent cell derived inhibitors of DNA synthesis |
| US5302706A (en) | 1991-12-16 | 1994-04-12 | Baylor College Of Medicine | Senescent cell derived inhibitors of DNA synthesis |
| ATE242806T1 (de) | 1992-10-16 | 2003-06-15 | Cold Spring Harbor Lab | Umlagerung des cyclin komlexes und seine darauf bezogenen anwendungen |
| GB9305448D0 (en) | 1993-03-17 | 1993-05-05 | British Tech Group | Semiconductor structure and method of manufacturing same |
| AU692794B2 (en) | 1993-08-30 | 1998-06-18 | Baylor College Of Medicine | Senescent cell-derived inhibitors of DNA synthesis |
| WO1995013375A1 (en) | 1993-11-10 | 1995-05-18 | The Johns Hopkins University | Tumor suppressor waf1 |
| WO1995031995A1 (en) | 1994-05-24 | 1995-11-30 | Baylor College Of Medicine | Mimetics of senescent cell derived inhibitors of dna synthesis |
| GB9422175D0 (en) | 1994-11-03 | 1994-12-21 | Univ Dundee | Indentification of the p21 waf1-pcna interaction site and therapeutic applications thereof |
| GB9509557D0 (en) | 1995-05-11 | 1995-07-05 | Univ Dundee | PCNA binding substance |
| AU6548396A (en) | 1995-07-20 | 1997-02-18 | Worcester Foundation For Biomedical Research, Inc. | Methods for selectively killing or inhibiting the growth of cells expressing the waf1 gene |
| US5672508A (en) | 1996-01-23 | 1997-09-30 | Mitotix, Inc. | Inhibitors of cell-cycle progression, and uses related thereto |
| WO1997042222A1 (en) | 1996-05-08 | 1997-11-13 | Cyclacel Limited | Methods and means for inhibition of cdk4 activity |
-
1997
- 1997-05-08 WO PCT/GB1997/001250 patent/WO1997042222A1/en not_active Ceased
- 1997-05-08 DE DE69736351T patent/DE69736351T4/de not_active Expired - Lifetime
- 1997-05-08 JP JP52963597A patent/JP4205165B2/ja not_active Expired - Fee Related
- 1997-05-08 US US09/180,269 patent/US6962792B1/en not_active Expired - Fee Related
- 1997-05-08 AU AU27077/97A patent/AU2707797A/en not_active Abandoned
- 1997-05-08 DE DE69736351A patent/DE69736351D1/de not_active Expired - Fee Related
- 1997-05-08 EP EP97920857A patent/EP0898580B9/en not_active Expired - Lifetime
- 1997-05-08 AT AT97920857T patent/ATE333465T1/de not_active IP Right Cessation
-
2003
- 2003-08-22 US US10/646,267 patent/US20040214765A1/en not_active Abandoned
-
2008
- 2008-06-04 US US12/133,242 patent/US20080249025A1/en not_active Abandoned