|
DE19624659A1
(de)
|
1996-06-20 |
1998-01-08 |
Klinge Co Chem Pharm Fab |
Neue Pyridylalken- und Pyridylalkinsäureamide
|
|
US6451816B1
(en)
|
1997-06-20 |
2002-09-17 |
Klinge Pharma Gmbh |
Use of pyridyl alkane, pyridyl alkene and/or pyridyl alkine acid amides in the treatment of tumors or for immunosuppression
|
|
JPH10338658A
(ja)
*
|
1997-04-08 |
1998-12-22 |
Hoechst Marion Roussel Kk |
レチノイド作用調節剤
|
|
US6903118B1
(en)
|
1997-12-17 |
2005-06-07 |
Klinge Pharma Gmbh |
Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides
|
|
DE19756212A1
(de)
|
1997-12-17 |
1999-07-01 |
Klinge Co Chem Pharm Fab |
Neue, mit einem cyclischen Imid substituierte Pyridylalkan-, alken- und -alkincarbonsäureamide
|
|
DE19756235A1
(de)
|
1997-12-17 |
1999-07-01 |
Klinge Co Chem Pharm Fab |
Neue piperidinylsubstituierte Pyridylalkan- alken- und -alkincarbonsäureamide
|
|
DE19756261A1
(de)
|
1997-12-17 |
1999-07-01 |
Klinge Co Chem Pharm Fab |
Neue arylsubstituierte Pyridylalkan-, alken- und alkincarbonsäureamide
|
|
DE19818044A1
(de)
*
|
1998-04-22 |
1999-10-28 |
Klinge Co Chem Pharm Fab |
Verwendung von Vitamin-PP-Verbindungen
|
|
JP2002522499A
(ja)
*
|
1998-08-12 |
2002-07-23 |
スミスクライン・ビーチャム・コーポレイション |
カルシウム分解化合物
|
|
EP1031564A1
(en)
|
1999-02-26 |
2000-08-30 |
Klinge Pharma GmbH |
Inhibitors of cellular nicotinamide mononucleotide formation and their use in cancer therapy
|
|
DE19908483A1
(de)
*
|
1999-02-26 |
2000-10-05 |
Klinge Co Chem Pharm Fab |
Inhibitoren der zellulären Niacinamidmononucleotid-Bildung
|
|
ATE278421T1
(de)
|
2000-08-11 |
2004-10-15 |
Wyeth Corp |
Verfahren zur behandlung eines östrogenrezeptor positives karzinoms
|
|
HUP0302302A2
(hu)
|
2000-09-29 |
2003-12-29 |
Glaxo Group Limited |
Morfolin-acetamid-származékok gyulladásos betegségek kezelésére, eljárás az előállításukra és ezeket tartalmazó gyógyszerkészítmények
|
|
EP1348434A1
(en)
*
|
2002-03-27 |
2003-10-01 |
Fujisawa Deutschland GmbH |
Use of pyridyl amides as inhibitors of angiogenesis
|
|
GB0207445D0
(en)
*
|
2002-03-28 |
2002-05-08 |
Glaxo Group Ltd |
Novel compounds
|
|
US7977049B2
(en)
|
2002-08-09 |
2011-07-12 |
President And Fellows Of Harvard College |
Methods and compositions for extending the life span and increasing the stress resistance of cells and organisms
|
|
KR100927915B1
(ko)
*
|
2005-03-17 |
2009-11-19 |
화이자 인코포레이티드 |
통증 치료에 유용한 ｎ-(ｎ-설폰일아미노메틸)사이클로프로판카복사마이드 유도체
|
|
PE20071159A1
(es)
|
2005-10-31 |
2007-11-30 |
Schering Corp |
Derivados de tropano 3-monosustituido como ligandos de receptores de nociceptina
|
|
US8067415B2
(en)
|
2005-11-01 |
2011-11-29 |
Millennium Pharmaceuticals, Inc. |
Compounds useful as antagonists of CCR2
|
|
WO2007053498A1
(en)
|
2005-11-01 |
2007-05-10 |
Millennium Pharmaceuticals, Inc. |
Compounds useful as antagonists of ccr2
|
|
HUP0600809A3
(en)
*
|
2006-10-27 |
2008-09-29 |
Richter Gedeon Nyrt |
New phenylsulfamoyl-benzamide derivatives as bradykinin antagonists, process and intermediates for their preparation and pharmaceutical compositions containing them
|
|
EP2098231A1
(en)
|
2008-03-05 |
2009-09-09 |
Topotarget Switzerland SA |
Use of NAD formation inhibitors for the treatment of ischemia-reperfusion injury
|
|
US9006426B2
(en)
|
2008-06-24 |
2015-04-14 |
Topotarget A/S |
Squaric acid derivatives as inhibitors of the nicotinamide
|
|
RU2011111728A
(ru)
|
2008-08-29 |
2012-10-10 |
Топотаргет А/С (Dk) |
Новые производные мочевины и тиомочевины
|
|
CA2768338A1
(en)
|
2009-07-17 |
2011-01-20 |
Topotarget A/S |
Method for predicting the utility of administering nicotinic acid or a precursor or prodrug thereof to reduce the severity of side-effects of cancer treatment with nicotinamide phosphoribosyltransferase inhibitors
|
|
WO2011121055A1
(en)
|
2010-03-31 |
2011-10-06 |
Topotarget A/S |
Pyridinyl derivatives comprising a cyanoguanidine or squaric acid moiety
|
|
SG188367A1
(en)
|
2010-09-03 |
2013-04-30 |
Forma Tm Llc |
Novel compounds and compositions for the inhibition of nampt
|
|
TW201217359A
(en)
|
2010-09-03 |
2012-05-01 |
Forma Therapeutics Inc |
Novel compounds and compositions for the inhibition of NAMPT
|
|
JP5881705B2
(ja)
|
2010-09-03 |
2016-03-09 |
フォーマ ティーエム， エルエルシー． |
Ｎａｍｐｔの阻害のための新規化合物及び組成物
|
|
BR112013006030B1
(pt)
*
|
2010-09-29 |
2020-03-17 |
Intervet International B.V. |
Composto e sais ou n-óxidos farmaceuticamente aceitáveis, e, uso do composto
|
|
EP2640704A1
(en)
|
2010-11-15 |
2013-09-25 |
Abbvie Inc. |
Nampt inhibitors
|
|
UY33726A
(es)
|
2010-11-15 |
2012-06-29 |
Abbott Lab |
Inhibidores de nampt y rock
|
|
KR20140027366A
(ko)
|
2011-05-04 |
2014-03-06 |
포르마 티엠, 엘엘씨. |
Nampt의 억제를 위한 신규 화합물 및 조성물
|
|
AR082889A1
(es)
|
2011-05-09 |
2013-01-16 |
Forma Therapeutics Inc |
Compuestos y composiciones para la inhibicion de nampt
|
|
CA2873097A1
(en)
|
2012-05-11 |
2013-11-14 |
Todd M. Hansen |
Pyridazine and pyridine derivatives as nampt inhibitors
|
|
CA2873075A1
(en)
|
2012-05-11 |
2013-07-14 |
Abbvie Inc. |
Nampt inhibitors
|
|
WO2013170118A1
(en)
|
2012-05-11 |
2013-11-14 |
Abbvie Inc. |
Thiazolecarboxamide derivatives for use as nampt inhibitors
|
|
HK1208221A1
(en)
|
2012-05-11 |
2016-02-26 |
Abbvie Inc. |
Nampt inhibitors
|
|
EP2925750A1
(en)
|
2012-11-29 |
2015-10-07 |
Karyopharm Therapeutics, Inc. |
Substituted 2,3-dihydrobenzofuranyl compounds and uses thereof
|
|
WO2015003166A1
(en)
|
2013-07-03 |
2015-01-08 |
Karyopharm Therapeutics Inc. |
Substituted benzofuranyl and benzoxazolyl compounds and uses thereof
|
|
US9994558B2
(en)
|
2013-09-20 |
2018-06-12 |
Karyopharm Therapeutics Inc. |
Multicyclic compounds and methods of using same
|
|
MA42655A
(fr)
|
2015-08-18 |
2021-04-07 |
Karyopharm Therapeutics Inc |
Acrylamide de (s,e)-3-(6-aminopyridin-3-yl)-n-((5-(4-(3-fluoro-3-méthylpyrrolidine-1-carbonyl)phényl)-7-(4-fluorophényl)benzofuran-2-yl)méthyl) pour le traitement du cancer
|
|
US10858347B2
(en)
|
2015-12-31 |
2020-12-08 |
Karyopharm Therapeutics Inc. |
Multicyclic compounds and uses thereof
|
|
KR20190074292A
(ko)
|
2016-10-18 |
2019-06-27 |
시애틀 지네틱스, 인크. |
니코틴아미드 아데닌 디뉴클레오티드의 구제 경로 저해제의 표적화된 전달
|
|
WO2018086703A1
(en)
|
2016-11-11 |
2018-05-17 |
Bayer Pharma Aktiengesellschaft |
Dihydropyridazinones substituted with phenylureas
|
|
CN110799217A
(zh)
|
2017-04-27 |
2020-02-14 |
西雅图基因公司 |
季铵化烟酰胺腺嘌呤二核苷酸补救途径抑制剂缀合物
|
|
CA3089754A1
(en)
|
2018-01-31 |
2019-08-08 |
Bayer Aktiengesellschaft |
Antibody drug conjugates (adcs) with nampt inhibitors
|
|
WO2021013693A1
(en)
|
2019-07-23 |
2021-01-28 |
Bayer Pharma Aktiengesellschaft |
Antibody drug conjugates (adcs) with nampt inhibitors
|
|
US20230023124A1
(en)
|
2019-11-06 |
2023-01-26 |
Remedy Plan, Inc. |
Cancer treatments targeting cancer stem cells
|
|
EP4337639A1
(en)
|
2021-05-13 |
2024-03-20 |
Remedy Plan, Inc. |
Nampt inhibitors and uses thereof
|